摘要
Shortly after its outbreak,coronavirus disease 2019(COVID-19)has very rapidly spread to become a global epidemic.Early clinical findings mainly included typical symptoms such as fever and cough with a very high transmission rate.Recent findings have demonstrated neurological manifestations of atypical symptoms,which is associated with poor prognosis.In this paper,we describe the neurological aspects of COVID-19 pneumonia in terms of relevant neurons,virus-associated receptors,and olfactory and neurological clinical manifestations and offer insights on treatment.
基金
supported by Beijing Darwin Emergency Fund for Basic Research(No.2020-B-01)
Zhejiang Science and Technology Development Foundation[2017]No.185(GF18H09008)
Zhejiang Health Development Foundation[2018]No.52(2019ZD058)
Shao City Science and Education Office[2015]No.15(2016KYB315)
Zhejiang Science and Education Office[2015]No.24(2015ZA209)
作者简介
Chao He,graduated from the Department of Clinical Medicine of Wenzhou Medical University,China,in July 2004.Now he is a neurosurgeon in Zhuji Affiliated Hospital of Wenzhou Medical University.In 2017,he was selected as the rookie of the medical field in Zhejiang Province.He has published many high-quality papers in Chinese and international journals,and has a number of patented technologies.He is a member of IANR.His research focuses on moyamoya disease,cerebral hemorrhage,and traumatic brain injuries.E-mail:zj.hechao@163.com,These authors contributed equally to this work;Ling He,received her Master’s degree in traditional Chinese medicine from Harbin University of Commerce,China,in 2011.Now she works in Beijing Darwin Cell Biotechnology Co.,Ltd.She has published a number of papers in Chinese core journals and participated in the research of national projects and emergency research projects.At present,she is mainly engaged in the clinical translational research of stem cell related products.E-mail:he86ling@163.com,These authors contributed equally to this work;Corresponding author:Lin Chen,received his Doctor’s degree in surgery from the School of Medicine of Tsinghua University in 2014.He served as an Editorial Director of Brain Science Advances,Associate Chief Physician of Neurosurgery Center of Tsinghua University Yuquan Hospital.Now he is the Director of Neurosurgery Department,Dongzhimen Hospital,Beijing University of Chinese Medicine.He has published many high-quality papers in Chinese and international journals,and has a number of patented technologies.His current researches focus on facial spasm,trigeminal neuralgia,Parkinsonʹs disease,cerebral infarction and other nervous system diseases.E-mail:chenlin_china@163.com,These authors contributed equally to this work;Corresponding author:Wei Wang,received her B.S.degree from the Wenzhou Medical College in July 2004.Now she is a clinician of intensive care unit in Zhuji People’s Hospital,Zhejiang,China.Her research focuses on emergency aid and treatment.E-mail:constance5@126.com,These authors contributed equally to this work
