摘要
目的:探讨子午流注针刺法联合关节腔注射臭氧治疗膝骨性关节炎的临床疗效及对关节功能和凝血机制的影响。方法:选取2016年1月~2021年1月安徽中医药大学第二附属医院收治的100例膝骨关节炎患者为研究对象,随机数字表法分为观察组和对照组,各50例。对照组仅给予关节腔注射臭氧治疗,观察组在对照组基础上增加子午流注针刺法治疗。比较两组患者的临床疗效、中医证候评分、膝关节功能、凝血指标和不良反应发生率。结果:观察组临床治疗总有效率为92.00%(46/50),高于对照组患者的74.00%(37/50)(P<0.05);治疗后观察组患者的中医证候积分均低于对照组(P<0.05);治疗后观察组膝关节HSS功能量表评分均高于对照组(P<0.05);治疗后观察组患者的凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)均高于对照组,纤维蛋白原(FIB)低于对照组(P<0.05);治疗期间两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:子午流注针刺法联合关节腔注射臭氧治疗膝骨性关节炎的疗效显著,能够改善患者的中医证候,提高患者的膝关节活动功能,改善患者的凝血功能异常状态,且安全性较好。
Objective:To study the clinical efficacy of acupuncture based on Midnight-Noon Cycle of Qi combined with intra-articular ozone injection in the treatment of knee osteoarthritis and its influence on joint function and coagulation mechanism.Methods:100 patients with knee osteoarthritis in our hospital from January 2016 to January 2021 were selected and divided into observation group and control group by random number table method,50 cases in each group.The control group was treated with intra-articular injection of ozone,while the observation group was treated with acupuncture based on Midnight-Noon Cycle of Qi on the basis of the control group.The clinical efficacy,TCM symptom score,knee function,coagulation index and incidence of adverse reactions of the two groups were evaluated and compared.Results:the total effective rate of the observation group was 92.00%(46/50),which was higher than 74.00%(37/50)of the control group(P<0.05).After treatment,the scores of TCM symptoms including swelling,pain,stiffness and claudication in the observation group were lower than those in the control group(P<0.05).After treatment,the HSS function scale of knee joint in the observation group including pain,function,range of motion,muscle strength,deformity and stability were higher than those in the control group(P<0.05).After treatment,the prothrombin time(PT),thrombin time(TT)and activated partial thromboplastin time(APTT)of the observation group were higher than those of the control group,and the fibrinogen(FIB)of the observation group was lower than that of the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups during the treatment period(P>0.05).Conclusion:acupuncture based on Midnight-Noon Cycle of Qi combined with intra-articular ozone injection has significant effect in the treatment of knee osteoarthritis,which can improve the symptoms of traditional Chinese medicine and the activity function of knee joint,improve the abnormal state of coagulation function,and has good safety.
作者
魏迎辰
杨玲玲
周忠良
WEI Yingchen;YANG Lingling;ZHOU Zhongliang(Department of orthopedics,Second Affiliated Hospital of Anhui University of traditional Chinese medicine,Hefei Anhui 230061,China)
出处
《四川中医》
2023年第4期184-187,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
国家中医药管理局中医药标准化项目[项目编号SATCM-2015-BZ(101)]
关键词
膝骨关节炎
臭氧关节腔注射
子午流注针刺法
关节功能
凝血机制
Knee osteoarthritis
Ozone intra-articular injection
acupuncture based on Midnight-Noon Cycle of Qi
Joint function
Coagulation mechanism
作者简介
魏迎辰,硕士,主治医师,主要从事骨伤疾病,骨关节研究,E-mail:414291005@qq.com。
