摘要
磁共振动脉自旋标记技术(ASL)是一种非侵入性的影像学技术,无需造影剂即可定量分析组织的血流灌注情况,可重复性高,对血流动力学相关指标敏感。本文主要介绍ASL在缺血性眼病及脑病中的应用,并与眼部、脑部其他常用的血管造影等检查进行比较。ASL能够对脑部血流状态变化进行监测,可预测脑部缺血性事件的发生,目前已广泛应用于缺血性脑病的研究。研究表明ASL能够直接反映脉络膜视网膜组织的供血状况,可作为定量眼部血流灌注的可靠方法,同时对脉络膜视网膜疾病的病理生理研究具有一定意义,可对缺血性眼病进行早期诊断。目前ASL在眼部的应用尚少,尚需进一步研究以明确ASL在缺血性眼病中的效用。
Arterial spin labeling(ASL)is a non-invasive imaging technique that permits the quantitative analysis of tissue perfusion without contrast agents,and it has been widely used in ischemic disease research.This paper introduces the application of ASL in the assessment of ischemic ophthalmopathy and encephalopathy and compares it with other common examination techniques of the eye and brain.ASL can be used to monitor changes in cerebral blood flow and predict ischemic events,and it has been widely used in the study of ischemic encephalopathy.It can directly reflect the dynamics of blood flow through the chorioretinal vasculature,and it can be used as a reliable method for quantifying ocular blood perfusion.ASL is also relevant for the pathophysiological studies of chorioretinal diseases,which may contribute to the early diagnosis of ischemic ophthalmopathies.Currently,the application of ASL in ophthalmology is still limited,and further studies are needed to establish the utility of ASL in assessing ischemic ophthalmopathy.
作者
周卓华(综述)
李红阳(审校)
黄映湘(审校)
王艳玲(审校)
ZHOU Zhuohua;LI Hongyang;HUANG Yingxiang;WANG Yanling(Department of Ophthalmology,Beijing Friendship Hospital affiliated to Capital Medical University,Beijing 100050,China)
出处
《山东大学耳鼻喉眼学报》
CAS
2020年第4期16-22,共7页
Journal of Otolaryngology and Ophthalmology of Shandong University
基金
国家自然科学基金资助(81870686)
首都卫生发展科研专项资助(首发2018-1-2021)
关键词
缺血性眼病
磁共振动脉自旋标记
缺血性脑病
诊断
磁共振成像
Ischemic ophthalmopathy
Arterial spin labeling
Ischemic encephalopathy
Diagnosis
Magnetic resonance imaging
作者简介
通信作者:黄映湘。E-mail:bshuang@163.com
