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IL-6抑制剂在全身型幼年特发性关节炎治疗中的应用进展 被引量:9

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摘要 全身型幼年特发性关节炎(systemic juvenile idiopathic arthritis,sJIA)是一种自身免疫性疾病,以发热、皮疹、肝脾肿大、淋巴结肿大以及浆膜炎为主要临床表现,细胞因子分泌水平升高是sJIA的典型特征。IL-6在sJIA的发病机制和临床表现中发挥重要作用,为该病的治疗提供了新思路。目前,有关IL-6抑制剂的临床试验已经展开,其具有一定的安全性和有效性。文章重点介绍IL-6抑制剂在sJIA临床治疗中的研究现状。
出处 《现代免疫学》 CAS CSCD 北大核心 2020年第2期174-178,共4页 Current Immunology
基金 南京医科大学面上项目(2016NJMV087).
作者简介 桂珍(1988-),女,硕士,初级检验师,主要从事临床免疫与生化检验工作;通信作者:陈小洁,(E-mail:457923189@qq.com)
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