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66例普通型新型冠状病毒肺炎恢复期患者中医临床特征分析 被引量:50

Analysis on TCM clinical characteristics of 66 COVID-19 cases in the recovery period
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摘要 目的分析上海地区普通型新型冠状病毒肺炎恢复期患者的中医证候分布特点。方法纳入曾于上海市公共卫生临床中心救治的普通型新型冠状病毒肺炎恢复期患者66例,于患者出院后24 h内完成数据收集,包括基本特征(性别、年龄、既往史、吸烟史、流行病学资料、住院期间的用药情况)、中医证候信息、舌象特征、病程,并依据《新型冠状病毒肺炎诊疗方案(试行第六版)》进行分析辨证。结果①普通型新型冠状病毒肺炎恢复期患者的主要症状为小便短黄、口渴、汗出、口苦、乏力、胸闷气短;舌象特征以红舌与黯红舌为主(77.3%),腻苔多见(53.0%);气阴两虚型患者占比81.8%,肺脾气虚型患者占比18.2%。②气阴两虚型患者中夹湿热证者20例(占比37.0%),肺脾气虚型患者中夹痰湿证者10例(占比83.3%),肺脾气虚型患者夹湿证发生率高于气阴两虚型患者(P<0.05)。③气阴两虚型患者病程长于肺脾气虚型(P<0.05),而是否兼夹湿证与患者的病程无明显相关(P>0.05)。结论气阴两虚为普通型新型冠状病毒肺炎恢复期的主要证型且病程较长,肺脾气虚型患者更易夹湿。 Objective To analyze the distribution characteristics of TCM syndromes in convalescent patients with coronavirus disease 2019(COVID-19)in Shanghai.Methods Sixty-six convalescent patients with COVID-19 who had been treated in Shanghai Public Health Clinical Center were included.Data collection was completed within 24 hours after the patient was discharged from hospital,including basic information(gender,age,past medical history,smoking history,epidemiological data and medication during hospitalization),TCM syndrome information,tongue image characteristics and course of disease,and analysis and differentiation were carried out according to the"COVID-19 Diagnosis and Treatment Program(Trial Implementation of the Sixth Edition)".Results①The main symptoms of convalescent patients with COVID-19 were short yellow urine,thirst,sweating,bitter mouth,fatigue,chest tightness and shortness of breath with red or dark red tongue(77.3%)and greasy coating(53.0%);The proportion of patients with dual deficiency of qi and yin was 81.8%,and that of patients with deficiency of lung and spleen qi was 18.2%.②There were 20 cases(37.0%)with damp-heat syndrome in patients with dual deficiency of qi and yin and 10 cases(83.3%)with phlegm-dampness syndrome in patients with lung and spleen qi deficiency(P<0.05).The incidence rate of dampness syndrome in patients with lung and spleen qi deficiency was higher than that in patients with dual deficiency of qi and yin(P<0.05).③The disease course in patients with dual deficiency of qi and yin was longer than that in patients with lung and spleen qi deficiency(P<0.05),but there was no significant correlation between the course of disease and whether the dampness syndrome was combined(P>0.05).Conclusion Dual deficiency of qi and yin is the main syndrome of patients with COVID-19 in the recovery period with a longer course of disease.Patients with deficiency of lung and spleen qi are more prone to be complicated with dampness syndrome.
作者 薛鸿浩 张惠勇 鹿振辉 陆城华 郭晓燕 张晔敏 毕蓉蓉 徐向前 孙朔 XUE Honghao;ZHANG Huiyong;LU Zhenhui;LU Chenghua;GUO Xiaoyan;ZHANG Yemin;BI Rongrong;XU Xiangqian;SUN Shuo(Department of Pulmonary Diseases,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)
出处 《上海中医药杂志》 2020年第5期46-49,共4页 Shanghai Journal of Traditional Chinese Medicine
基金 国家“十三五”传染病重大专项课题(2017ZX10305501-002) 上海市中医药管理局中医药防治新型冠状病毒肺炎应急专项(2020NCP001) 上海市科委科研计划项目(18495810600)
关键词 新型冠状病毒肺炎 新型冠状病毒 普通型 恢复期 中医证候 气阴两虚 肺脾气虚 COVID-19 SARS-CoV-2 moderate type recovery period TCM syndrome dual deficiency of qi and yin lung and spleen qi deficiency
作者简介 薛鸿浩,男,副主任医师,主要从事中医药治疗肺系疾病的临床与研究工作。;通信作者:孙朔,副主任医师。E-mail:18601692315@163.com
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