摘要
目的评价针刺治疗女性不孕症系统评价的方法学质量和结局指标的可靠程度。方法通过检索Cochrane Library、Pubmed、Web of science、中国知网、中国生物医学文献库、维普网和万方数据库,收集针刺治疗女性不孕症的系统评价/Meta分析。采用AMSTAR 2量表评价纳入研究的方法学质量,运用GRADE系统评价结局指标的质量分级。结果共纳入13篇系统评价,AMSTAR 2评定结果仅1篇方法学质量为中等级,5篇低等级,7篇极低等级。GRADE评级结果显示,中等质量结局指标5个,低质量15个,极低质量15个。结论目前针刺治疗女性不孕症与空白对照或假/安慰针刺和西药促排相比可提高临床妊娠率,尤其在取卵日前后或ET(Embryo-transfer)日及前后可以增加临床妊娠率,而对其他指标没有体现明显优势,但其方法学质量和结局指标的可靠程度相对较低,期待未来有更多高质量的研究提供可靠的临床证据。
Objective To evaluate the methodological quality and reliability of outcome indicators of systematic evaluation of acupuncture treatment for female infertility.Method Cochrane Library,Pubmed,Web of science,CNKI.CBM,VIP and Wanfang databases were searched by computer to collect systematic evaluation/meta-analysis of acupuncture treatment for female infertility.AMSTAR 2 scale was used to evaluate the methodological quality of the study,and GRADE system was used to classify the outcome indicators.Result A total of 13 systematic reviews were included.AMSTAR 2 scores showed that the quality of one research methodology was of medium grade,5 were of low grade and 7 were of very low grade.GRADE rating results showed that there were 5 medium quality outcome indicators,15 low quality indicators and 15 very low quality indicators.Conclusion Currently,acupuncture treatment of female infertility can improve the clinical pregnancy rate by comparing with blank control,sham/placebo acupuncture and western medicine prophylaxis.In particular,it can increase the clinical pregnancy rate before and after the day of oocyte retrieval or embryo transfer,while it has no obvious advantage over other indicators,but the reliability of systematic evaluation in methodological quality and outcome indicators is relatively low,and more high-quality studies are expected to provide reliable clinical evidence in the future.
作者
侯廷惠
郑倩华
封秀梅
石云舟
刘颖
李瑛
Hou Tinghui;Zheng Qianhua;Feng Xiumei;Shi Yunzhou;Liu Ying;Li Ying(School of Acupuncture and Massage,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Graduate School of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2020年第8期2780-2789,共10页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家科学技术部支撑计划项目(2012BAI24B01):针灸治疗围绝经期综合征与功能性便秘等国际多中心随机对照临床试验,负责人:李瑛
作者简介
通讯作者:李瑛,教授,博士生导师,主要研究方向:循证医学与针灸临床疗效评价。
