摘要
2型糖尿病是由遗传和环境因素共同引起慢性血糖升高的一种代谢性疾病,可表现为多饮、多食、多尿和体重减轻,目前并不能彻底根治。如果患者血糖长期得不到控制,将引起严重并发症。肠道菌群是人体内最大的微生态系统,对人体的物质和能量代谢有着重要影响。研究发现,肠道菌群是影响2型糖尿病发生发展的重要因素。已有大量的研究证明,T2DM患者与健康人的肠道菌群的结构与多样性有所差异,中医药可以通过改善T2DM患者的菌群失调情况,从而治疗2型糖尿病。传统的中医药疗法具有多种方式且各具特色,中药效果温和且不良反应少,针灸推拿依从性好,中医食疗具有独特的饮食理论优势。随着科技的发展,益生菌发酵中药也走上舞台,其扬长避短,具有很大的发掘价值。由此可见,中医药通过肠道菌群治疗2型糖尿病还有很大的研究空间,具有广阔的发展前景。
Type 2 diabetes mellitus is a metabolic disease caused by a combination of genetic and environmental factors that causes chronic hyperglycemia,which can manifest as polydipsia,polyphagia,polyuria and weight loss.At present,it cannot be completely cured.If the patient's blood sugar is not controlled for a long time,it will cause serious complications.The intestinal flora is the largest microecosystem in the human body and has an important influence on the body's material and energy metabolism.Studies have found that the intestinal flora is an important factor affecting the occurrence and development of Type 2 diabetes mellitus.A large number of studies have proved that the structure and diversity of the intestinal flora of T2DM patients and healthy people are different.Traditional Chinese medicine can treat type 2 diabetes by improving the dysbacteriosis in T2DM patients.Traditional Chinese medicine therapy has a variety of methods and each has its own characteristics.Chinese medicine has mild effects and few adverse reactions.Acupuncture and massage compliance is good.Chinese medicine diet has a unique dietary theory advantage.With the development of science and technology,probiotic fermented traditional Chinese medicine has also entered the stage.It promotes strengths and avoids weaknesses and has great exploration value.It can be seen that there is still a lot of research space for traditional Chinese medicine to treat type 2 diabetes through intestinal flora,and it has broad development prospects.
作者
宋雪梅
金小琴
秦合伟
李彦杰
牛雨晴
王梦楠
Song Xuemei;Jin Xiaoqin;Qin Hewei;Li Yanjie;Niu Yuqing;Wang Mengnan(School of Rehabilitation Medicine,Henan University of Chinese Medicine,Zhengzhou 450046,China;The Second Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450002,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2023年第4期1199-1204,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
河南省科技厅自然基金项目青年基金(212300410191):参苓白术散通过SGLT1通路发挥降糖作用的机制研究,负责人:金小琴
关键词
2型糖尿病
肠道菌群
血糖
中医药疗法
Type 2 diabetes mellitus
Intestinal flora
Blood Sugar
Traditional Chinese medicine therapy
作者简介
通讯作者:金小琴,讲师,主要研究方向:糖尿病的中医药治疗。
