摘要
目的输血是救治患者生命的一种重要治疗方法,本研究分析2014-2018年沈阳地区无偿献血者血液检测情况,为本地区采供血工作提供科学依据。方法选择2014-01-01-2018-12-31沈阳地区无偿献血者为研究对象,共计869723人次采用两种不同试剂对其血液标本进行传染病检测,对检测结果进行统计分析。结果2014-2018年沈阳地区无偿献血者血液检测总体不合格率为1.35%,其中梅毒螺旋体(TP)和丙氨酸氨基转移酶(ALT)是主要不合格项,不合格率分别为0.36%和0.56%;乙型肝炎表面抗原(HBsAg)为0.17%,丙型肝炎病毒(HCV)为0.10%,人类免疫缺陷病毒(HIV)为0.07%。不同年份的ALT(χ2=598.05,P<0.01)、HBsAg(χ2=101.95,P<0.01)、HCV(χ2=586.35,P<0.01)、HIV(χ2=148.36,P<0.01)和TP(χ2=304.34,P<0.01)检测不合格率比较,差异有统计学意义。双试剂阳性检出率TP最高,达到0.25%,不同年份HBsAg(χ2=75.97,P<0.01)、HCV(χ2=136.84,P<0.01)、HIV(χ2=49.12,P<0.01)和TP(χ2=258.94,P<0.01)双阳检出率比较,差异有统计学意义。结论TP和ALT是沈阳地区无偿献血者主要不合格项目,HCV不合格率和双阳检出率处于较低水平。应加强对初次献血者的问询、对重复献血者的历史记录查询,增加ALT和TP项目的献血前快速筛查,降低血液报废率,提高血液质量,确保用血安全。
Objective Blood transfusion is an important treatment method to save the lives of patients.This study analyzed the blood testing of unpaid blood donors in Shenyang from 2014 to 2018,and provided a scientific strategy for blood collection and supply in this area.Methods A total of 869723 unpaid blood donors in Shenyang from January 1,2014 to December 31,2018 were selected as the research subjects.Two different manufacturers’reagents were used to detect infectious diseases on their blood samples,and the test results were statistically analyzed.Results The overall unqualified rate of blood test for unpaid blood donors in Shenyang from 2014 to 2018 was 1.35%.Treponema pallidum(TP)and alanine aminotransferase(ALT)were the main unqualified items,and the unqualified rates were 0.36%and 0.56%.Hepatitis B surface antigen(HBsAg)was 0.17%,hepatitis C virus(HCV)was 0.10%,and human immunodeficiency virus(HIV)was 0.07%.Compared with the unqualified rate of ALT(χ2=598.05,P<0.01),HBsAg(χ2=101.95,P<0.01),HCV(χ2=586.35,P<0.01),HIV(χ2=148.36,P<0.01)and TP(χ2=304.34,P<0.01)in different years,the difference was statistically significant.The double-reagent positive detection rate TP was the highest,reaching0.25%.Compared with the detection rate of double positive of HBsAg(χ2=75.97,P<0.01),HCV(χ2=136.84,P<0.01),HIV(χ2=49.12,P<0.01)and TP(χ2=258.94,P<0.01)in different years,the difference was statistically significant.Conclusions TP and ALT are the main unqualified items of unpaid blood donors in shenyang,and the unqualified rate of HCV and the detection rate of shuangyang are at a low level.It is necessary to strengthen the inquiry of first-time blood donors and the historical records of repeat blood donors,increase the rapid screening of ALT and TP items before blood donation,reduce blood rejection rate,improve blood quality,and ensure blood safety.
作者
隋丽红
王芳
SUI Li-hong;WANG Fang(Department of Laboratory,Liaoning Provincial Blood Center,Shenyang110044,China)
出处
《社区医学杂志》
CAS
2021年第1期14-16,20,共4页
Journal Of Community Medicine
关键词
无偿献血
血液检测
传染病
梅毒螺旋体
丙氨酸氨基转移酶
unpaid blood donation
blood test
infectious disease
treponema pallidum
alanine aminotransferase
作者简介
通信作者:隋丽红,女,内蒙古赤峰人,副主任检验师,主要从事血液传染病检测方面的研究工作。E-mail:15309884462@189.cn
