摘要
目的通过对2009-2020年日照市东港区报告的手足口病流行病学特征进行分析,了解手足口病的流行现状及其发病规律,为今后科学、精准防治手足口病提供参考。方法采用描述性流行病学方法对2009-2020年日照市东港区报告的手足口病资料进行统计分析。结果2009-2020年日照市东港区累计报告手足口病19568例,重症257例,死亡1例,年均报告发病率为174.98/10万。报告发病率最高为2010年,报告发病率为548.61/10万;最低为2020年,报告发病率为3.49/10万,不同年份报告发病率差异有统计学意义(P<0.01),总体发病呈下降趋势(P<0.01)。实验室诊断675例,其中肠道病毒71型(EV71)、柯萨奇病毒A组16型(CoxA16)和其他肠道病毒分别为278、138和259例。19568例手足口病病例中,重症病例257例,占1.31%;轻症病例19311例,占98.69%。全年各月均有发病,发病有季节性高峰,5-8月为发病高峰时间。城区发病高于乡镇,差异有统计学意义,P<0.01。<5岁年龄组发病为主,发病18142例,发病率达2483.17/10万,占发病总数的92.71%。散居儿童和托幼儿童发病18876例,占发病总数的96.46%。男性发病率高于女性,P<0.01。结论2009-2020年日照市东港区手足口病发病率呈逐年下降趋势,发病呈季节性高峰。城区和<5岁儿童为手足口病防控的重点地区和重点人群,病原学以其他肠道病毒和EV71型病毒为主。
Objective To analyze the epidemiological characteristics of hand-foot-mouth disease(HFMD)in Donggang District of Rizhao,so as to provide reference for better prevention and control HFMD.Methods Descriptive epidemiology methods were used to analyze the data of HFMD reported in Donggang District of Rizhao City from 2009 to 2020.Results Totally 15968 cases of HFMD were reported from 2009 to 2020,including 257 severe cases and 1 death.The average annual incidence rate was 174.98/100000.The highest incidence rate was reported in 2010,and the incidence rate was 548.61/100000.The lowest incidence was 2020,the reported incidence rate was 3.49/100000,and the incidence rate of reported diseases in different years was statistically significant(P<0.01).The overall incidence showed a downward trend(P<0.01).675 cases were diagnosed in the laboratory,including 278 cases of human enterovirus 71(EV71),138 cases of coxsackie virus A16(CoxA16)and 259 cases of other enteroviruses,respectively.Among 19568 cases of HFMD,257 cases were severe cases,accounting for 1.31%;there were 19311 mild cases,accounting for 98.69%.The disease occurs in every month of the year,with a seasonal peak,and the peak time is from May to August.The incidence in urban areas was higher than that in rural areas(P<0.01).The incidence rate of age group was below 5 years old,with a total number of 18142 cases.The incidence rate was 2483.17/100000,accounting for 92.71%of the total number of diseases.There were 18876 scattered children and nursery children,accounting for 96.46%of the total incidence.The incidence rate of male was higher than that of female(P<0.01).Conclusions The incidence rate of HFMD in Donggang District of Rizhao City has been decreasing year by year,and the incidence is seasonal peak in 2009-2020 years.Urban areas and children under 5 years old are the key areas and populations for the prevention and control of HFMD,and the etiology is mainly other enteroviruses and EV71 viruses.
作者
贺玉芬
王伟光
何娜
尚明风
HE Yu-fen;WANG Wei-guang;HE Na;SHANG Ming-feng(Department of Infectious Disease Control,Rizhao Donggang Center for Disease Control and Prevention,Rizhao 276800,China;Department of Infectious Disease Control,Rizhao City for Disease Control and Prevention,Rizhao 276800,China)
出处
《社区医学杂志》
CAS
2022年第11期591-595,共5页
Journal Of Community Medicine
关键词
手足口病
肠道病毒
流行特征
日照市
hand-food-mouth disease
enterovirus
epidemiology characteristics
Rizhao City
作者简介
通信作者:贺玉芬,女,山东日照人,副主任医师,主要从事传染性疾病流行病学的研究工作。E-mail:870096005@qq.com
