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持续性低效率血液透析滤过治疗顽固性心力衰竭合并肾功能不全患者的疗效

Effect of Sustained Low-Efficiency Hemodialfiltration in the Treatment of Patients with Refractory Heart Failure Combined with Renal Insufficiency
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摘要 目的探究持续性低效率血液透析滤过治疗顽固性心力衰竭合并肾功能不全患者的临床效果。方法选取2020年12月-2021年12月我院接收的60例顽固性心力衰竭合并肾功能不全患者,采取双盲法将其随机分为实验组和对照组,每组各30例。实验组采用持续性低效率血液透析滤过治疗,对照组采用连续性静脉-静脉血液滤过治疗,观察两组患者的治疗效果。结果实验组单次治疗时间和总治疗时间均小于对照组(P<0.001),治疗后两组患者左心室射血分数、心排出量、尿素氮和肌酐差别具有统计学意义(P<0.001),治疗后两组患者并发出血情况差异具有统计学意义(X2=13.080,P<0.001)。结论对于顽固性心力衰竭合并肾功能不全患者行持续性低效率血液透析滤过治疗效果更加显著,并发出血发生率更低,更为安全可靠。 Objective:To explore the clinical effect of sustained low-efficiency hemodialfiltration in the treatment of patients with refractory heart failure combined with renal insufficiency.Methods:From December 2020 to December 202160 patients with refractory heart failure and renal insufficiency who were admitted to our hospital were selected,and were randomly divided into the experimental group and the control group in a double-blind method,with 30 cases in each group.The experimental group was treated with sustained low-efficiency hemodialfiltration,and the control group was treated with continuous venous-venous hemofiltration.The therapeutic effects of the two groups were observed.Results:The duration of single treatment and the total treatment time in the experimental group were much shorter than those in the control group(P<0.001).The left ventricular ejection fraction,cardiac output,urea nitrogen and creatinine in the two groups were significantly different after treatment(P<0.001).The bleeding status of patients in the two groups after treatment was significantly different(X2=13.080,P<0.001).Conclusion:The sustained low-efficiency hemodiafiltration has more significant effect on patients with refractory heart failure and renal insufficiency,and the incidence of bleeding is lower,which is more safe and reliable.
作者 叶文兵 YE Wen-bing(Pengze County People's Hospital,Jiujiang Jiangxi 332700,China)
机构地区 彭泽县人民医院
出处 《透析与人工器官》 2023年第1期34-37,共4页 Chinese Journal of Dialysis and Artificial Organs
关键词 顽固性心力衰竭 肾功能不全 血液透析滤过 refractory heart failure renal insufficiency hemodiafiltration
作者简介 通讯作者:叶文兵
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