摘要
目的分析新疆26例新冠肺炎患者临床特征及流行病学特点。方法回顾性分析2020年1月20日-3月01日新疆某地区26例新型冠状病毒肺炎患者一般资料,分析其流行病学特征、临床表现、实验室检查和影像学检查特点。结果26例2019-nCoV感染患者中,男性12例,女性14例;平均年龄为46.4±13.6岁。患者中9例(34.6%)聚集性发病、余17例(65.4%)均密切或间接接触确诊患者后的输入性病例。临床分型:19例普通型,7例重型,其中1死亡病例。临床症状包括发热23例(88.5%)、咳嗽咳痰21例(80.7%)、乏力6例(23.1%)、腹泻6例(23.1%);较不少见的症状是咽痛3例(11.5%)、肌肉痛或关节痛3例(11.5%)。重症患者淋巴细胞计数(0.86<1.0×10^(9)/L)平均值较非重症患者(1.97<1.0×10^(9)/L)明显减低;重症患者白蛋白计数(36.11 g/L)平均值较非重症患者(44.73 g/L)明显减低;重症患者乳酸脱氢酶值(170.21U/L)平均值较非重症患者(89.49U/L)明显升高;重症患者D二聚体值(4.49 mg/L)平均值较非重症患者(0.81 mg/L),明显升高;以上比较差异均具有统计学意义。治疗中并发症包括急性呼吸窘迫综合征4例(15.8%)、消化道出血1例(3.8%),尚未发现有明显肝肾功能损伤和其他感染情况发生。结论新疆某地区新型冠状病毒肺炎病例主要以输入性病例和聚集性病例为主。临床表现以发热、乏力、咳嗽为主。危/重症患者出现血淋巴计数及白蛋白水平降低、二聚体及血乳酸水平升高的比例升高。
Objective To analyze the clinical and epidemiological characteristics of 26 patients with COVID-19 in Xinjiang.Methods To retrospectively analyze the general data of 26 patients with COVID-19 in a certain area in Xinjiang from January 20 to March 1,2020,and analyze their epidemiological characteristics,clinical manifestations,laboratory examinations and imaging examination characteristics.Results Among the 26 patients with 2019-nCoV infection,12 were males and 14 were females;the average age was46.4±13.6 years.Among the patients,9 cases(34.6%)had cluster disease,and the remaining 17 cases(65.4%)were imported cases after close or indirect contact with the confirmed patients.Clinical classification:19 cases of general type,7 cases of severe type,including1 death case.Clinical symptoms included fever in 23 cases(88.5%),cough and sputum in 21 cases(80.7%),fatigue in 6 cases(23.1%),diarrhea in 6 cases(23.1%);Less common symptoms were sore throat in 3 cases(11.5%)and Muscle pain or arthralgia in 3 cases(11.5%).The average lymphocyte count of severe patients(0.86<1.0×109/L)was significantly lower than that of non-severe patients(1.97<1.0×109/L);the average albumin count of severe patients(36.11 g/L)was significantly lower than that of non-severe patients(44.73 g/L);the average value of lactate dehydrogenase in severe patients(170.21 U/L)was significantly higher than that of non-severe patients(89.49 U/L);the value of D dimer in severe patients(4.49 mg/L)The average value was significantly higher than that of non-severe patients(0.81 mg/L);the differences above are statistically significant.Complications during treatment included 4 cases of acute respiratory distress syndrome(15.8%)and 1 case of gastrointestinal hemorrhage(3.8%).No obvious liver and kidney function damage and other infections had been found.Conclusion The main cases of COVID-19 in a certain area of Xinjiang are mainly imported cases and cluster cases.The clinical manifestations were mainly fever,fatigue,and cough.Critical/severe patients have decreased of hemolymph counts and albumin levels,and increased levels of dimers and blood lactate.
作者
张洁
曾圣涛
张韬
郑嵘炅
努力比亚·阿不都克尤
鲁晓擘
ZHANG Jie;ZENG Shengtao;ZHANG Tao;ZHENG Rongjiong;Nulibiya Abudukeyou;LU Xiaobo(Infectious Liver Disease Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;Xinhua Hospital of Yili Kazak Autonomous State,Yili 835000,Xinjiang,China)
出处
《新疆医学》
2021年第7期766-770,共5页
Xinjiang Medical Journal
基金
国家自然科学基金(项目编号:81660333)
关键词
2019新型冠状病毒
临床表现
流行病学
治疗
2019 Novel Coronavirus disease(COVID-19)
clinical features
epidemiology
treatment
作者简介
张洁,女,硕士,住院医师,研究方向:传染病、肝衰竭诊治;通信作者:鲁晓擘,男,博士,主任医师,研究方向:传染病及肝病诊治,E-mail:xjykdluxiaobo@126.com。
