摘要
目的观察阶梯式呼吸训练联合穴位贴敷治疗职业性煤工尘肺病(CWP)的临床疗效。方法采用方便抽样方法,选择80例男性职业性CWP患者为研究对象;采用随机数表法分为对照组和治疗组,每组各40例。对照组患者予常规对症治疗,治疗组在对照组治疗的基础上予阶梯式呼吸训练联合穴位贴敷治疗12周。观察2组患者治疗前后临床疗效、肺功能、免疫功能、《慢性阻塞性肺疾病评估测试(CAT)问卷》总分和6 min步行试验距离(6MWD)的变化。结果治疗前,2组患者用力肺活量(FVC)、FVC与第1秒末用力呼气容积(FEV1)比值(FEV1/FVC)、淋巴细胞分化抗原(CD)4+/CD8+比值、自然杀伤细胞(NK)百分比、CAT总分、6MWD分别比较,差异均无统计学意义(P>0.05)。治疗后,与对照组比较,治疗组患者FVC、FEV1/FVC和淋巴细胞CD4+/CD8+比值均升高(中位数:78.3%vs 80.7%,68.7%vs 72.5%,1.16 vs 2.00,P<0.01),6MWD升高[(430.6±45.9)vs(494.8±58.7)m,P<0.01],CAT总分下降[(18.1±5.6)vs(15.5±5.3)分,P<0.01]。2组患者淋巴细胞NK百分比比较,差异无统计学意义(P>0.05)。治疗组患者治疗总有效率高于对照组(90.0%vs 57.5%,P<0.01)。结论阶梯式呼吸训练联合穴位贴敷治疗可改善CWP患者的咳嗽、气短等临床症状,改善肺功能,调节免疫功能,提高运动耐力。
Objective To observe the clinical effect of multistep breathing training combined with acupoint plastering on the treatment of patients with occupational coal worker’s pneumoconiosis(CWP).Methods Eighty cases of male occupational CWP patients were selected as the research subject using convenient sampling method.They were divided into control group(40 cases)and treatment group(40 cases)according to random number table method.The control group was given conventional treatment,while the treatment group received multistep respiratory training combined with acupoint plastering for 12 weeks based on conventional symptomatic treatment.Before and after treatment,clinical curative effect,pulmonary function,immune function,the total score of Chronic Obstructive Pulmonary Disease Assessment Test(CAT)Questionnaire and 6 minutes walk distance(6 MWDS)in two groups were observed.Results Before treatment,there was no statistical difference on forced vital capacity(FVC),ratio of forced expiratory volume in one second(FEV1)/FVC,lymphocyte cluster of differentiation(CD)4+/CD8+ratio,percentage of natural killer cells(NK),total CAT scores and 6 MWD(P>0.05).After treatment,the FVC,FEV1/FVC ratio and lymphocyte CD4+/CD8+ratio increased[median:78.3%vs 80.7%,68.7%vs 72.5%,1.16 vs 2.00,P<0.01],6 MWD was increased[(430.6±45.9)vs(494.8±58.7)m,P<0.01],and CAT total score was decreased[(18.1±5.6)vs(15.5±5.3)points,P<0.01]in the treatment group compared with the control group.There was no significant difference in NK cell percentage between the two groups(P>0.05).Conclusion Multistep respiratory training combined with acupoint plastering can alleviate the clinical symptoms such as cough,and shortness of breath of patients with CWP,improve their lung function,regulate the function of immunity,as well as improve sports endurance.
作者
王慧娟
赵凤玲
李洁雅
许雪春
王永杰
WANG Huijuan;ZHAO Fengling;LI Jieya;XU Xuechun;WANG Yongjie(Henan Institute of Occupational Medicine(Henan Occupational Disease Hospital),Zhengzhou,Henan 450052,China)
出处
《中国职业医学》
CAS
北大核心
2020年第3期334-338,共5页
China Occupational Medicine
基金
河南省中医药科学研究专项课题(2018ZY1003)
关键词
呼吸训练
穴位贴敷
煤工尘肺
肺功能
免疫功能
治疗
临床效果
Breathing training
Acupoint plastering
Coal worker′s pneumoconiosis
Lung function
Immunity function
Treatment
Clinical effect
作者简介
王慧娟(1983—),女,中医内科学硕士,主治医师,主要从事职业病的中西医治疗。;通信作者:赵凤玲,主任医师,E-mail:zzzfl1626@126.com
