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抑郁在老年胃肠肿瘤患者睡眠与术前衰弱间的中介效应 被引量:4

Mediating effect of depression on sleep and preoperative frailty in elderly patients with gastrointestinal cancer
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摘要 目的探讨抑郁在老年胃肠肿瘤患者睡眠与术前衰弱间的中介作用。方法采用便利抽样法选取219例老年胃肠肿瘤患者,采用一般资料问卷、匹兹堡睡眠质量指数、患者健康问卷抑郁量表及Tilburg衰弱量表调查抑郁、睡眠与术前衰弱的关系。结果抑郁和睡眠对术前衰弱有显著正影响(β=0.326、0.179,t=3.905、1.977,P<0.05)。抑郁在睡眠与术前衰弱间起部分中介作用(β=0.179,VAF=47.97%,P=0.043)。结论抑郁、睡眠与术前衰弱关系密切,睡眠可直接或通过抑郁间接影响术前衰弱的发生。医护人员应重视老年患者术前睡眠及抑郁状态,对术前睡眠质量差且无法改善的患者,可以通过缓解患者术前抑郁情绪来降低术前衰弱的发生率。 Objective To investigate the mediating role of depression in sleep and preoperative frailtyin elderly patients with gastrointestinal cancer.Methods A total of 219 elderly patients with gastrointestinal cancer were selected by convenience sampling method.The general information questionnaire,Pittsburgh Sleep Quality Index,Patient Health Questionnaire-9 and Tilburg Frailty Indicator were used to investigate the correlations between depression as well as sleep and preoperative frailty.Results Sleep and depression had direct positive effects on preoperative frailty in elderly patients with gastrointestinal cancer(β=0.326,0.179,t=3.905,1.977,P<0.05);depression partially mediated in sleep and preoperative frailty(β=0.179,VAF=47.97%,P=0.043).Conclusion Depression and sleep are closely related to preoperative frailty,and the latter can directly affect preoperative frailty,or indirectly affect the occurrence of preoperative frailty through depression.Medical staff should pay attention to the evaluation and treatment of sleep quality and depression of elderly patients before operation.For patients with poor preoperative sleep quality and difficulty in improvement,we can alleviate the preoperative depression to reduce the incidence of preoperative frailty.
作者 郤丽娟 王道荣 方方 袁海娟 XI Lijuan;WANG Daorong;FANG Fang;YUAN Haijuan(School of Nursing of Yangzhou University,Yangzhou,Jiangsu,225009;Clinical Medical College of Yangzhou University,Yangzhou,Jiangsu,225001;Yangzhou University-General Surgery Institute of Yangzhou,Yangzhou,Jiangsu,225001;Northern Jiangsu People's Hospital of Jiangsu Province,Yangzhou,Jiangsu,225001)
出处 《实用临床医药杂志》 CAS 2021年第5期50-54,共5页 Journal of Clinical Medicine in Practice
基金 国家自然科学基金资助项目(81972269)
关键词 睡眠 抑郁 术前衰弱 中介作用 sleep depression preoperative frailty mediating effect
作者简介 通信作者:王道荣,wdaorong666@sina.com
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