摘要
艾灸作为传统中医外治法之一,具有药物作用及温热作用,可以温经散寒、活血行气。核因子-κB(NF-κB)作为一种核转录因子,参与人体内多种疾病的病理过程,可调节炎症反应、免疫应答、应激反应等,影响多种细胞因子的表达。近年来研究发现,艾灸可多靶点、多层面调控NF-κB通路,发挥治疗作用。查阅近年来研究艾灸对NF-κB通路影响的实验,对艾灸调控NF-κB通路的作用机制进行总结分析,为今后开展艾灸对不同疾病中NF-κB通路的机制研究提供参考。
As one of the external treatment methods of traditional Chinese medicine,moxibustion has the effect of medicine and warming heat at the same time,it can warm channel and dissipate cold,activate blood circulation and activate qi.Nuclear factor-kappa B(NF-κB),as a nuclear transcription factor,participates in the pathological process of many diseases in human body,regulates inflammatory response,immune response,stress response and so on,and affects the expression of many kinds of cytokines.In recent years,studies have found that moxibustion can regulate NF-κB pathway at multiple targets and levels,and play a therapeutic role.Refer to the experiments on the effect of moxibustion on NF-κB pathway in recent years,summarize and analyze the mechanism of moxibustion regulating NF-κB pathway,in order to provide reference for the future research on the mechanism of moxibustion on NF-κB pathway in different diseases.
作者
尚娅男
陆文婷
张淋麟
罗小超
钟玉梅
周海燕
Shang Yanan;Lu Wenting;Zhang Linlin;Luo Xiaochao;Zhong Yumei;Zhou Haiyan(College of Acupuncture and Tuina/Third Affiliated Hospital,Chengdu University of Traditional Chinese Medicine,Chengdu 610000,China)
出处
《亚太传统医药》
2020年第12期202-205,共4页
Asia-Pacific Traditional Medicine
基金
国家重点研发计划(2019YFC1709001)
国家自然科学基金(81973959,81674068,81403480)
四川省中医药管理局基础性研究项目(2018JC007)
成都中医药大学基金(QNXZ2018034)
关键词
艾灸
NF-ΚB
作用机制
Moxibustion
NF-kappa B
Mechanism of Action
作者简介
尚娅男(1996-),女,成都中医药大学硕士研究生,研究方向为针灸治疗类风湿性关节炎的基础研究和经穴效应研究。E-mail:840794173@qq.com;通讯作者:周海燕(1979-),女,博士,成都中医药大学副教授,硕士生导师,研究方向为针灸治疗类风湿性关节炎的基础研究和经穴效应研究。E-mail:5014296@qq.com
