摘要
目的 探讨优质护理干预对肺癌化疗患者癌性疲乏、睡眠质量的影响。方法 选取2017年12月—2018年11月河南科技大学第一附属医院收治的100例肺癌化疗患者作为研究对象,按照非盲随机数字表法分为观察组和对照组,每组50例。对照组接受常规护理,观察组在此基础上接受优质护理,3个月后对比两组患者Piper疲乏自评修正量表(piper Fatigue self rating correction scale,RPFS)、匹兹堡睡眠质量指数(pittsburgh sleep quality index,PSQI)、癌胚抗原(carcinoembryonic antigen,CEA)、糖类抗原72-4 (carbohydrate antigen 72-4,CA72-4)、糖类抗原19-9 (carbohydrate antigen 19-9,CA19-9)变化,记录护理期间不良反应。结果 与护理前比较,两组患者的情感、躯体、行为、认知及总分均降低,且观察组上述各项指标评分均低于对照组,差异有统计学意义(P<0.05);护理后,两组患者睡眠质量、入睡时间、睡眠效率、睡眠障碍、安眠药物等各项指标评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05);护理后,两组患者的血清肿瘤标志物CEA、CA72-4、CA19-9水平均降低,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组不良反应总发生率为12.00%,明显低于对照组(30.00%),差异有统计学意义(P<0.05)。结论 优质护理干预肺癌化疗患者,可改善患者癌性疲乏程度,提高睡眠质量,降低肿瘤标志物水平,减少不良反应。
Objective This study explored the effects of a high-quality nursing intervention on cancer-related fatigue and sleep quality in patients undergoing lung cancer chemotherapy. Methods A total of 100 patients undergoing lung cancer chemotherapy, admitted to the First Affiliated Hospital of Henan University of Science and Technology between December 2017 and November 2018, were selected and divided into observation and control groups according to the randomized number table method, with 50 patients per group.The control group received routine care, and the observation group received quality care. After 3 months, the Piper Self-assessment Correction Scale(RPFS), Pittsburgh Sleep Quality Index(PSQI), cancer embryonic antigen(CEA), glucose antigen 72-4(CA72-4), and glucose antigen 19-9(CA19-9) were recorded. Results The emotional, physical, behavioral, cognitive, and total scores of the two groups of patients decreased after nursing, and the scores of the above indicators in the observation group were lower than those in the control group(all P<0.05). After nursing, the scores of sleep quality, time to fall asleep,sleep efficiency, sleep disorders, use of sleeping drugs, and other indicators decreased in both groups, and the values were lower in the observation group than the control group(P<0.05). After nursing, the serum tumor markers CEA, CA72-4, andCA19-9 decreased, and the values were lower in the observation group than the control group(P<0.05). The total incidence of adverse reactions in the observation group was(12.00%),a value lower than in the control group(30.00%)(P<0.05). Conclusion A high-quality nursing intervention for patients undergoing lung cancer chemotherapy can decrease cancer-related fatigue, improve sleep quality, anddecrease the levels of tumor markers and adverse reactions.
作者
李倩
LI Qian(The First Affiliated Hospital of Henan University of Science and Technology,Luoyang,471000,China)
出处
《慢性病学杂志》
2022年第3期388-392,共5页
Chronic Pathematology Journal
关键词
肺癌
化疗
优质护理
癌性疲乏
睡眠质量
不良反应
Lung cancer
Chemotherapy
Quality care
Cancer fatigue
Sleep quality
Adverse reactions
作者简介
通讯作者:李倩,大学本科,护师,研究方向:护理,E-mail:liy9851@163.com