摘要
目的分析探讨在小儿呼吸道感染中血清炎症因子、免疫球蛋白诊断价值。方法研究对象为2019年1月至2020年1月在我院治疗的120例小儿呼吸道感染作为观察组,同时选取同期的120例健康的体检者作为对照组,测定两组研究对象的血清炎症因子、免疫球蛋白情况,以判断血清炎症因子、免疫球蛋白对该疾病诊断价值。结果经检测后发现,观察组患者入院时以及治疗一周后的IgG、IgM以及IgA值均显著低于对照组的,差异具有统计学意义(P<0.05);观察组患者治疗一周后的IgG、IgM以及IgA值均显著高于观察组患者入院时的值,差异具有统计学意义(P<0.05);观察组患者入院时以及治疗一周后的TNF-ɑ、IL-1β以及IL-10值均显著高于对照组的,差异具有统计学意义(P<0.05);观察组患者治疗一周后的TNF-ɑ、IL-1β以及IL-10值均显著低于观察组患者入院时的值,差异具有统计学意义(P<0.05);经Pearson相关性分析得出,疾病康复程度与炎症因子水平呈正相关,与TNF-ɑ、IL-1β、IL-10对应的r值分别为0.864、0.899、0.811,差异具有统计学意义(P<0.05);疾病康复与免疫球蛋白水平成负相关,与IgG、IgM、IgA对应的r值分别为-0.780、-0.804、-0.709,差异具有统计学意义(P<0.05)。结论在小儿呼吸道感染中血清炎症因子、免疫球蛋白值的变化情况对疾病发生以及疾病治疗情况有较高的应用价值,有助于对患者病情和治疗效果进行判断,值得临床上大力推广使用。
Objective To analyze the diagnostic value of serum inflammatory factors and immunoglobulins in children with respiratory tract infection.Methods 120 children with respiratory tract infection treated in our hospital from January 2019 to January 2020 were selected as the observation group,and 120 healthy physical examinees were selected as the control group at the same time.The serum inflammatory factors and immunoglobulins of the two groups were measured to determine the diagnostic value of serum inflammatory factors and immunoglobulins for the disease.Results It was found that the values of IgG,IgM and IgA in the observation group were significantly lower than those in the control group(P<0.05),and the values of IgG,IgM and IgA in the observation group were significantly higher than those in the observation group(P<0.05)The TNF-α,IL-1βand IL-10 in the observation group were significantly higher than those in the control group(P The R values of TNF-α,IL-1βand IL-10 were 0.864,0.899 and 0.811),respectively,and the difference was statistically significant(P<0.05);the R values of disease rehabilitation and immunoglobulin were negatively correlated,and the R values of IgG,IgM and IgA were-0.780,-0.804 and-0.709,respectively,and the difference was statistically significant(P<0.05).Conclusion The changes of serum inflammatory factors and immunoglobulin values in children with respiratory tract infection have high application value for disease occurrence and disease treatment,help to judge the patient’s condition and treatment effect,and are worth popularizing in clinic.
作者
田慧舒
乔志坤
颉雅苹
TIAN Hui-shu;QIAO Zhi-kun;JIE Ya-ping(Guangzhou women and children medical center,Guangzhou,Guangdong 510623)
出处
《智慧健康》
2020年第16期97-99,共3页
Smart Healthcare
关键词
血清炎症因子
小儿呼吸道感染
免疫球蛋白
诊断价值
Serum inflammatory factors
Children’s respiratory tract infection
Immunoglobulin
Diagnostic value
