摘要
目的观察整脊通督方案联合小剂量氟哌啶醇对小儿多发性抽动症(TS)合并寰枢关节错位眨眼症状的影响。方法选择在浙江省中医院推拿科门诊就诊、以眨眼为主诉的TS合并寰枢关节错位患儿54例,随机分为对照组26例和治疗组28例。对照组给予氟哌啶醇0.5 mg/次,2次/d,其后依据病情酌情增量,但每日总量不超过6 mg;治疗组采用理筋、寰枢椎整复及辨证手法组成的整脊通督方案联合氟哌啶醇0.25 mg/次,1次/d。2组均以45 d为1个治疗周期,分别于治疗第15,30,45天,对试验方案进行疗效评价。结果2组治疗第15,30,45天,眨眼次数、频率、强度得分均有所下降,与同组治疗前比较,差异有统计学意义(P<0.05);治疗后第15天,治疗组眨眼次数、频率、强度得分与对照组比较,差异无统计学意义(P>0.05);第30,45天,治疗组上述观察指标均优于对照组,差异有统计学意义(P<0.05)。2组治疗第15,30,45天,改良耶鲁综合抽动严重程度量表(YGTSS)总积分均较同组治疗前下降,但差异无统计学意义(P>0.05);第30,45天,治疗组明显优于对照组,差异有统计学意义(P<0.05)。对照组不良反应发生率为61.54%,明显高于治疗组的21.42%,2组比较,差异有统计学意义(P<0.01)。结论整脊通督方案联合小剂量氟哌啶醇能有效改善TS合并寰枢关节错位患儿的眨眼症状,减少不良反应的发生。
Objective To observe the influence on Tourette syndrome(TS)complicated with atlantoaxial joint dislocation and blinking in children treated with chiropractic and dredging governor vessel therapy.Methods 54 cases of TS complicated with atlantoaxial dislocation that blinking as the chief complaint were randomly divided into 26 cases in the control group and 28 in the treatment group,which were treated in the department of massage in Zhejiang hospital of traditional Chinese medicine.The control group was given 0.5 mg haloperidol,2 times a day,and then increased as appropriate according to the condition,but the total daily dose did not exceed 6 mg.The treatment group was treated with chiropractic and dredging governor vessel therapy composed of tendon-regulation,atlantoaxial reconstruction and differentiation treatment,combined with haloperidol 0.25 mg every time,1 times a day.Both groups were treated with 45 days as a treatment cycle,and the curative effects were evaluated on the 15 th,30 th and45 th days of treatment.Results On the 15 th,30 th and 45 th days of the 2 groups,the number,frequency,and intensity of eyelid blinking were all reduced,compared with before treatment,the difference was statistically significant(P<0.05);on the 15 th day after treatment,there was no significant difference in the number,frequency and intensity of blinks between the treatment group and the control group(P>0.05);on the 30 th and 45 th day,those above observations in treatment group were better than that in the control group,and the difference was statistically significant(P<0.05).On the 15 th,30 th and 45 th days of the 2 groups of treatment,the total score of the modified Yale Global Tie Severity Scale(YGTSS)was lower than that of the same group before treatment,but the difference was not statistically significant(P>0.05);on the 30 th and 45 th days,treatment group was significantly better than the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the control group was 61.54%,which was significantly higher than that in the treatment group(21.42%),there was a statistically significant difference between the two groups(P<0.01).Conclusion Chiropractic and dredging governor vessel therapy combined with low dosage haloperidol can effectively improve the blink symptoms and reduce the incidence of adverse reactions of TS complicated with atlantoaxial malposition in children.
作者
金昕
叶树良
JIN Xin;YE Shuliang(Massage Department,Zhejiang Hospital of Traditional Chinese Medicine,Hangzhou,Zhejiang,310006,China)
出处
《中医儿科杂志》
2018年第4期55-59,共5页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
多发性抽动症
眨眼
整脊通督方案
氟哌啶醇
临床观察
Tourette syndrome
blink
chiropractic and dredging governor vessel therapy
haloperidol
clinical observation
作者简介
金昕(1989-),男,住院医师,医学硕士,主要从事脊柱相关疾病的推拿治疗工作。
