摘要
缺血性脑卒中具有高发病率、高致残率和高死亡率的特点,目前缺乏有效的治疗方法,因此降低缺血性脑卒中的发病风险具有重要意义。研究表明维生素C能预防动脉粥样硬化,降低缺血性脑卒中的发病风险,但由于研究对象差异、维生素C含量评价方法不一致、混杂因素影响等,这一结论仍存在争议。本文从动物实验研究、临床研究和队列研究三个方面对维生素C降低缺血性脑卒中发病风险的研究结果进行综述,为后续研究提供参考。
Ischemic stroke is characterized by high morbidity,disability and mortality.At present,there is a lack of effective treatment for ischemic stroke,so it is of great significance to reduce the incidence risk of ischemic stroke.Studies show that vitamin C can prevent atherosclerosis,thus reduce the incidence risk of ischemic stroke.However,this point is controversial due to the differences of study population,inconsistent evaluation methods of vitamin C content and the influence of various confounding factors.This paper reviews the related animal experiments,clinical trials and cohort studies,in order to provide reference for subsequent studies on reducing the incidence risk of ischemic stroke.
作者
严倩倩(综述)
段世伟(综述)
蒙家嘉(综述)
韩丽媛(审校)
YAN Qianqian;DUAN Shiwei;MENG Jiajia;HAN Liyuan(Medical Genetics Center,School of Medicine,Ningbo University,Ningbo,Zhejiang 315211,China;不详)
出处
《预防医学》
2021年第7期685-688,共4页
CHINA PREVENTIVE MEDICINE JOURNAL
基金
国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项(2018YFC1315305)
作者简介
严倩倩,硕士在读;通信作者:韩丽媛,E-mail:hanliyuan@ucas.ac.cn
