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CT定位微创治疗联合羚角钩藤汤对高血压脑出血疗效及GCS评分、Barthel指数变化研究 被引量:15

Study on Curative Effect and Changes of GCS Score and Barthel Index of CT Positioning Minimally Invasive Treatment Combined with Lingjiao Gouteng Decoction(羚角钩藤汤)for Hypertensive Cerebral Hemorrhage
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摘要 目的研究CT定位微创治疗联合羚角钩藤汤对高血压脑出血疗效及格拉斯哥昏迷评分(GCS)、Barthel指数变化。方法选择2019年5月—2020年9月医院收治的高血压脑出血患者116例为研究对象,按照随机数字表法分成观察组和对照组、各58例,对照组采用脱水、降颅压常规处理及CT定位微创治疗,观察组在对照组基础上采用羚角钩藤汤治疗。比较两组患者的疗效,血肿总体积变化,GCS评分,Barthel指数,并发症。结果观察组愈显率为67.2%(39/58),显著高于对照组的48.3%(28/58),组间差异有统计学意义(P<0.05),观察组治疗总有效率为98.3%(57/58),略高于对照组的94.8%(55/58),但组间差异无统计学意义(P>0.05)。治疗前两组CT影像检查显示血肿总体积差异无统计学意义(P>0.05),治疗后均显著降低(P<0.05),但组间差异仍无统计学意义(P>0.05)。治疗前两组GCS评分差异无统计学意义(P>0.05),治疗后均显著升高(P<0.05),并且观察组显著高于对照组(P<0.05)。治疗前两组Barthel指数差异无统计学意义(P>0.05),治疗后均显著升高(P<0.05),并且观察组显著高于对照组(P<0.05)。观察组、对照组并发症发生率分别为6.9%(4/58)、8.6%(5/58),观察组略低于对照组,差异无统计学意义(P>0.05)。结论CT定位微创治疗联合羚角钩藤汤对高血压脑出血疗效满意,能够在保证疗效、安全性的基础上,更好地改善患者的意识状态及日常生活能力,值得推广。 Objective To study the curative effect and changes of GCS score and Barthel index of CT positioning minimally invasive treatment combined with Lingjiao Gouteng Decoction(羚角钩藤汤)for hypertensive cerebral hemorrhage.Methods A total of 116 patients with hypertensive cerebral hemorrhage admitted to the hospital from May 2019 to September 2020 were selected as the research objects.The patients were divided into observation group and control group according to the random number table method,58 cases in each group.The control group used dehydration and intracranial pressure reduction routine treatment and CT positioning minimally invasive treatment.The observation group was treated with Lingjiao Gouteng Decoction on the basis of the control group.The curative effect,total hematoma volume change,Glasgow coma score(GCS),Barthel index and complications were compared between two groups.Results The cure rate of the observation group was 67.2%(38/58)which was significantly higher than 48.3%(28/58)of the control group.The difference between two groups was statistically significant(P<0.05).The total effective rate of observation group was 98.3%(57/58)which was slightly higher than 94.8%(55/58)of control group.There was no statistical significance difference(P>0.05).The CT imaging examination of two groups before treatment showed no significant difference in total hematoma volume(P>0.05)and they were significantly reduced after treatment(P<0.05),but the difference between two groups was still not statistically significant(P>0.05).There was no significant difference in GCS scores between two groups before treatment(P>0.05)and they were significantly increased after treatment(P<0.05).The GCS score of the observation group was significantly higher than that of the control group(P<0.05).There was no significant difference in Barthel index between two groups before treatment(P>0.05),and they were significantly increased after treatment(P<0.05).The Barthel index of the observation group was significantly higher than that of the control group(P<0.05).The incidences of complications in the observation group and control group were 6.9%(4/58)and 8.6%(5/58),respectively.The incidence of the observation group was slightly lower than that of the control group and the difference was not statistically significant(P>0.05).Conclusion CT positioning minimally invasive treatment combined with Lingjiao Gouteng Decoction is satisfactory for hypertensive intracerebral hemorrhage.On the basis of ensuring the efficacy and safety,it can better improve the patients'consciousness and ability of daily living and so it is worthy of promotion.
作者 贾西中 崔群建 冯涛 孙杰 柳德学 胡成旺 潘瑞华 邓倩 王博 JIA Xizhong;CUI Qunjian;FENG Tao;SUN Jie;LIU Dexue;HU Chengwang;PAN Ruihua;DENG Qian;WANG Bo(First Affiliated Hospital of Nanyang Medical College,Nanyang 473058,Henan,China)
出处 《中华中医药学刊》 CAS 北大核心 2022年第5期206-208,共3页 Chinese Archives of Traditional Chinese Medicine
基金 河南省医学教育研究项目(wjlx2019292)
关键词 高血压 脑出血 CT定位 微创治疗 羚角钩藤汤 疗效 hypertension cerebral hemorrhage CT localization minimally invasive treatment Lingjiao Gouteng Decoction(羚角钩藤汤) effect
作者简介 贾西中(1971-),男,河南南阳人,副主任医师,学士,研究方向:医学影像诊断。
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