Atherosclerosis is a chronic inflammatory disease in arteries. Nuclear factor-kappa B (NF-κB),a redox-sensitive transcription factor,has been indicated to play a critical role in both initiation and expansion of athe...Atherosclerosis is a chronic inflammatory disease in arteries. Nuclear factor-kappa B (NF-κB),a redox-sensitive transcription factor,has been indicated to play a critical role in both initiation and expansion of atherosclerosis. Activation of NF-κB activates a variety of target genes that promote inflammation,such as leukocyte adhesion molecules,cytokines,and chemokines,as well as genes that regulate cell proliferation and differentiation. Multiple risk factors relevant to atherosclerosis including hypertension,diabetes mellitus,smoking and lipoprotein disorders also activate NF-κB. Thus the activation of NF-κB may be linked to the onset of atherosclerosis.展开更多
以石墨烯-壳聚糖复合膜修饰玻碳电极,并在此复合膜上电沉积纳米铜,用于葡萄糖的无酶检测。以扫描电镜、傅立叶红外光谱及电化学交流阻抗谱对该复合膜微观形态进行表征,以循环伏安法、计时电流法对该电极的电化学行为进行研究。实验结果...以石墨烯-壳聚糖复合膜修饰玻碳电极,并在此复合膜上电沉积纳米铜,用于葡萄糖的无酶检测。以扫描电镜、傅立叶红外光谱及电化学交流阻抗谱对该复合膜微观形态进行表征,以循环伏安法、计时电流法对该电极的电化学行为进行研究。实验结果表明,在0.1 mol/L Na OH溶液中修饰电极对葡萄糖具有良好的催化氧化作用,该电极对葡萄糖的检测线性范围为5.6×10-5~1.2×10-3mol/L,检出限(S/N=3)为2.3×10-5mol/L。该修饰电极对样品的检测具有良好的稳定性、重现性。展开更多
文摘Atherosclerosis is a chronic inflammatory disease in arteries. Nuclear factor-kappa B (NF-κB),a redox-sensitive transcription factor,has been indicated to play a critical role in both initiation and expansion of atherosclerosis. Activation of NF-κB activates a variety of target genes that promote inflammation,such as leukocyte adhesion molecules,cytokines,and chemokines,as well as genes that regulate cell proliferation and differentiation. Multiple risk factors relevant to atherosclerosis including hypertension,diabetes mellitus,smoking and lipoprotein disorders also activate NF-κB. Thus the activation of NF-κB may be linked to the onset of atherosclerosis.
文摘以石墨烯-壳聚糖复合膜修饰玻碳电极,并在此复合膜上电沉积纳米铜,用于葡萄糖的无酶检测。以扫描电镜、傅立叶红外光谱及电化学交流阻抗谱对该复合膜微观形态进行表征,以循环伏安法、计时电流法对该电极的电化学行为进行研究。实验结果表明,在0.1 mol/L Na OH溶液中修饰电极对葡萄糖具有良好的催化氧化作用,该电极对葡萄糖的检测线性范围为5.6×10-5~1.2×10-3mol/L,检出限(S/N=3)为2.3×10-5mol/L。该修饰电极对样品的检测具有良好的稳定性、重现性。
