乳铁蛋白(Lactoferrin,Lf)是分子量大小约为80 k Da的铁离子结合糖蛋白,是转铁蛋白(Transferrin,Tf)家族的成员之一。其理化性质独特,具有抑菌、抗病毒、抗癌、免疫调节、调节铁离子的吸收等诸多生物学功能。获得高产且有生物活性的重...乳铁蛋白(Lactoferrin,Lf)是分子量大小约为80 k Da的铁离子结合糖蛋白,是转铁蛋白(Transferrin,Tf)家族的成员之一。其理化性质独特,具有抑菌、抗病毒、抗癌、免疫调节、调节铁离子的吸收等诸多生物学功能。获得高产且有生物活性的重组乳铁蛋白,并用于临床治疗,一直是研究热点。随着基因工程技术的发展,已获得多个可表达重组乳铁蛋白的表达系统。本文对乳铁蛋白的理化性质、生物学活性、临床研究以及目前的重组表达系统进行综述,以期为乳铁蛋白的临床应用提供参考。展开更多
In order to understand the physiological and biochemical reasons of leafcolor transformation in Loropetalum chinense var. rubrum,three types of L. chinense var. rubrum, Zihei (black purple), Zihong(red purple)and Hong...In order to understand the physiological and biochemical reasons of leafcolor transformation in Loropetalum chinense var. rubrum,three types of L. chinense var. rubrum, Zihei (black purple), Zihong(red purple)and Hongzhe(red_ochre), and L. chinense were taken as materials. The contents of chlorophyll, carotenoid and soluble sugar, and activity of phenylalanine ammonialyase (PLA) in the leaves were measured from early March to June. The results showed that the contents of chlorophyll, carotenoid and soluble sugar increased gradually during the leafcolor changing from red to green, but there were obviously differences among types of Zihei, Zihong and Hongzhe. Anthocyanins contents in Zihe and Zihong leaves maintained high level, so their leaves still kept red when they got mature in early June. Phenylalanine ammonialyase (PLA) activity decreased, and had positive relationship with anthocyanin contents. Some measures such as shading or watering to lower air temperature could be taken to maintain leaves of L. chinense var. rubrum fresh red during summer.展开更多
文摘乳铁蛋白(Lactoferrin,Lf)是分子量大小约为80 k Da的铁离子结合糖蛋白,是转铁蛋白(Transferrin,Tf)家族的成员之一。其理化性质独特,具有抑菌、抗病毒、抗癌、免疫调节、调节铁离子的吸收等诸多生物学功能。获得高产且有生物活性的重组乳铁蛋白,并用于临床治疗,一直是研究热点。随着基因工程技术的发展,已获得多个可表达重组乳铁蛋白的表达系统。本文对乳铁蛋白的理化性质、生物学活性、临床研究以及目前的重组表达系统进行综述,以期为乳铁蛋白的临床应用提供参考。
文摘In order to understand the physiological and biochemical reasons of leafcolor transformation in Loropetalum chinense var. rubrum,three types of L. chinense var. rubrum, Zihei (black purple), Zihong(red purple)and Hongzhe(red_ochre), and L. chinense were taken as materials. The contents of chlorophyll, carotenoid and soluble sugar, and activity of phenylalanine ammonialyase (PLA) in the leaves were measured from early March to June. The results showed that the contents of chlorophyll, carotenoid and soluble sugar increased gradually during the leafcolor changing from red to green, but there were obviously differences among types of Zihei, Zihong and Hongzhe. Anthocyanins contents in Zihe and Zihong leaves maintained high level, so their leaves still kept red when they got mature in early June. Phenylalanine ammonialyase (PLA) activity decreased, and had positive relationship with anthocyanin contents. Some measures such as shading or watering to lower air temperature could be taken to maintain leaves of L. chinense var. rubrum fresh red during summer.
基金supported by grants from Tianjin Natural Scientific Foundation(14JCZDJC32800)National Basic Research Program of China(2015CB553905)+1 种基金Hi-Tech Research and Development Program of China(2014AA020903)The National Natural Science Foundation of China(81372186)~~
