According to the hypothesis of "Maintaining normal configuration", the polymers with the structure of sulfo-ammonium inner salt would be nonthrombogenic. In this paper, a series of polymers of 3-N,N-dimethyl...According to the hypothesis of "Maintaining normal configuration", the polymers with the structure of sulfo-ammonium inner salt would be nonthrombogenic. In this paper, a series of polymers of 3-N,N-dimethyl-3-N-methacryloyloxyethyl ammonium propanesulfonate(DMAPS) and its copolymers with polyethyleneglycol monomethylether methacrylate were prepared by using different concentrations of monomers and crosslinking agent. Their blood compatibilities were evaluated by platelet adhesion method. The results show that PDMAPS is of excellent platelet adhesion resistance.展开更多
A kind of sulfobetaine, N,N-dimethyl-N-(3- sulfopropyl )-4-ethen yl-benzenemethanaminium inner salt was synthesized from tertiary amine and propanesultone and characterized by IR a nd 1 H NMR . The blood compatibiliti...A kind of sulfobetaine, N,N-dimethyl-N-(3- sulfopropyl )-4-ethen yl-benzenemethanaminium inner salt was synthesized from tertiary amine and propanesultone and characterized by IR a nd 1 H NMR . The blood compatibilities of the polymers were evaluate d by platelet adhesion method. No platelet adhesion in platelet rich plasma(PRP) was observed for two hours.展开更多
文摘According to the hypothesis of "Maintaining normal configuration", the polymers with the structure of sulfo-ammonium inner salt would be nonthrombogenic. In this paper, a series of polymers of 3-N,N-dimethyl-3-N-methacryloyloxyethyl ammonium propanesulfonate(DMAPS) and its copolymers with polyethyleneglycol monomethylether methacrylate were prepared by using different concentrations of monomers and crosslinking agent. Their blood compatibilities were evaluated by platelet adhesion method. The results show that PDMAPS is of excellent platelet adhesion resistance.
文摘A kind of sulfobetaine, N,N-dimethyl-N-(3- sulfopropyl )-4-ethen yl-benzenemethanaminium inner salt was synthesized from tertiary amine and propanesultone and characterized by IR a nd 1 H NMR . The blood compatibilities of the polymers were evaluate d by platelet adhesion method. No platelet adhesion in platelet rich plasma(PRP) was observed for two hours.