A high bioactive flavonol veronicafolin was obtained from a Tibetan medicine Chrysosplenium nudicaule Bunge . The supermolecular solubilization of β cyclodextrin( β CD) and hydroxypropyl β cyclodextrin (HP β CD) o...A high bioactive flavonol veronicafolin was obtained from a Tibetan medicine Chrysosplenium nudicaule Bunge . The supermolecular solubilization of β cyclodextrin( β CD) and hydroxypropyl β cyclodextrin (HP β CD) on the flavonol has been investigated by a phase solubility method. The results revealed the formation of 1∶1 inclusion complex between flavonol and HP β CD dramatically increased the solubility of the flavonol, whereas β CD decreased its solublility. The complex constant K f for HP β CD and flavonol is 4 5×10 6 L/mol.展开更多
文摘A high bioactive flavonol veronicafolin was obtained from a Tibetan medicine Chrysosplenium nudicaule Bunge . The supermolecular solubilization of β cyclodextrin( β CD) and hydroxypropyl β cyclodextrin (HP β CD) on the flavonol has been investigated by a phase solubility method. The results revealed the formation of 1∶1 inclusion complex between flavonol and HP β CD dramatically increased the solubility of the flavonol, whereas β CD decreased its solublility. The complex constant K f for HP β CD and flavonol is 4 5×10 6 L/mol.
