摘要
A high bioactive flavonol veronicafolin was obtained from a Tibetan medicine Chrysosplenium nudicaule Bunge . The supermolecular solubilization of β cyclodextrin( β CD) and hydroxypropyl β cyclodextrin (HP β CD) on the flavonol has been investigated by a phase solubility method. The results revealed the formation of 1∶1 inclusion complex between flavonol and HP β CD dramatically increased the solubility of the flavonol, whereas β CD decreased its solublility. The complex constant K f for HP β CD and flavonol is 4 5×10 6 L/mol.
A high bioactive flavonol veronicafolin was obtained from a Tibetan medicine Chrysosplenium nudicaule Bunge . The supermolecular solubilization of β cyclodextrin( β CD) and hydroxypropyl β cyclodextrin (HP β CD) on the flavonol has been investigated by a phase solubility method. The results revealed the formation of 1∶1 inclusion complex between flavonol and HP β CD dramatically increased the solubility of the flavonol, whereas β CD decreased its solublility. The complex constant K f for HP β CD and flavono...
出处
《应用化学》
CAS
CSCD
北大核心
2004年第11期1190-1192,共3页
Chinese Journal of Applied Chemistry
关键词
黄酮醇
Β-环糊精
羟丙基β-环糊精
相溶解度
flavonol Veronicafolin
β-cyclodextrin
hydroxypropyl β-cyclodextrin
phase solubility
