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Spatial-temporal Patterns of Land-use Change in Typical Transect Area Along China National Highway 106 During 1996-2008
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作者 LIU Yu LIU Yansui +1 位作者 GUO Liying LU Shasha 《Journal of Northeast Agricultural University(English Edition)》 CAS 2011年第3期39-46,共8页
Based on land-use database updated with the survey of 1996, 2000, 2004 and 2008, this paper analyzed the land-use changes in the typical transect area along National Highway 106 with the aid of GIS technology and quan... Based on land-use database updated with the survey of 1996, 2000, 2004 and 2008, this paper analyzed the land-use changes in the typical transect area along National Highway 106 with the aid of GIS technology and quantitative models. The results showed that arable land had been continuously decreased from 1996 to 2008, with a loss of 65.85× 10^3 hm2 and an average decrement of 5.49×10^3 hm^2 per year, and the loss in northern areas was larger; garden land and woodland were gradually centralized to the predominance area with an increment of 25.73×10^3 hm2 and 22.37×10^3 hm2, respectively; residential and industrial land increased year after year, and the transportation land showed the equalized developing spatial pattern; the increment of construction land and encroachment on arable land in the area were deeply influenced by the national macroscopic land-use policies, the rapid advance of urbanization and the development level of the regional economy. Through this case study, it is suggested that differential land- use policies should be adopted to create good environmental conditions to guarantee food security and to promote the economic development. 展开更多
关键词 land-use change mechanism analysis transect area along China National Highway 106
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Predicting Hepatocellular Carcinoma Using Brightness Change Curves Derived From Contrast-enhanced Ultrasound Images
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作者 CHEN Ying-Ying JIANG Shang-Lin +3 位作者 HUANG Liang-Hui ZENG Ya-Guang WANG Xue-Hua ZHENG Wei 《生物化学与生物物理进展》 北大核心 2025年第8期2163-2172,共10页
Objective Primary liver cancer,predominantly hepatocellular carcinoma(HCC),is a significant global health issue,ranking as the sixth most diagnosed cancer and the third leading cause of cancer-related mortality.Accura... Objective Primary liver cancer,predominantly hepatocellular carcinoma(HCC),is a significant global health issue,ranking as the sixth most diagnosed cancer and the third leading cause of cancer-related mortality.Accurate and early diagnosis of HCC is crucial for effective treatment,as HCC and non-HCC malignancies like intrahepatic cholangiocarcinoma(ICC)exhibit different prognoses and treatment responses.Traditional diagnostic methods,including liver biopsy and contrast-enhanced ultrasound(CEUS),face limitations in applicability and objectivity.The primary objective of this study was to develop an advanced,lightweighted classification network capable of distinguishing HCC from other non-HCC malignancies by leveraging the automatic analysis of brightness changes in CEUS images.The ultimate goal was to create a user-friendly and cost-efficient computer-aided diagnostic tool that could assist radiologists in making more accurate and efficient clinical decisions.Methods This retrospective study encompassed a total of 161 patients,comprising 131 diagnosed with HCC and 30 with non-HCC malignancies.To achieve accurate tumor detection,the YOLOX network was employed to identify the region of interest(ROI)on both B-mode ultrasound and CEUS images.A custom-developed algorithm was then utilized to extract brightness change curves from the tumor and adjacent liver parenchyma regions within the CEUS images.These curves provided critical data for the subsequent analysis and classification process.To analyze the extracted brightness change curves and classify the malignancies,we developed and compared several models.These included one-dimensional convolutional neural networks(1D-ResNet,1D-ConvNeXt,and 1D-CNN),as well as traditional machine-learning methods such as support vector machine(SVM),ensemble learning(EL),k-nearest neighbor(KNN),and decision tree(DT).The diagnostic performance of each method in distinguishing HCC from non-HCC malignancies was rigorously evaluated using four key metrics:area under the receiver operating characteristic(AUC),accuracy(ACC),sensitivity(SE),and specificity(SP).Results The evaluation of the machine-learning methods revealed AUC values of 0.70 for SVM,0.56 for ensemble learning,0.63 for KNN,and 0.72 for the decision tree.These results indicated moderate to fair performance in classifying the malignancies based on the brightness change curves.In contrast,the deep learning models demonstrated significantly higher AUCs,with 1D-ResNet achieving an AUC of 0.72,1D-ConvNeXt reaching 0.82,and 1D-CNN obtaining the highest AUC of 0.84.Moreover,under the five-fold cross-validation scheme,the 1D-CNN model outperformed other models in both accuracy and specificity.Specifically,it achieved accuracy improvements of 3.8%to 10.0%and specificity enhancements of 6.6%to 43.3%over competing approaches.The superior performance of the 1D-CNN model highlighted its potential as a powerful tool for accurate classification.Conclusion The 1D-CNN model proved to be the most effective in differentiating HCC from non-HCC malignancies,surpassing both traditional machine-learning methods and other deep learning models.This study successfully developed a user-friendly and cost-efficient computer-aided diagnostic solution that would significantly enhances radiologists’diagnostic capabilities.By improving the accuracy and efficiency of clinical decision-making,this tool has the potential to positively impact patient care and outcomes.Future work may focus on further refining the model and exploring its integration with multimodal ultrasound data to maximize its accuracy and applicability. 展开更多
关键词 computer-aided diagnostic deep learning hepatocellular carcinoma contrast-enhanced ultrasound brightness change curve
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Impacts of climate change on cotton production and advancements in genomic approaches for stress resilience enhancement
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作者 KHAN Muhammad Aamir ANWAR Saeed +5 位作者 ABBAS Mubashir ANEEQ Muhammad DE JONG Fokke AYAZ Muhammad WEI Yunxiao ZHANG Rui 《Journal of Cotton Research》 2025年第2期270-289,共20页
Cotton is an essential agricultural commodity,but its global yield is greatly affected by climate change,which poses a serious threat to the agriculture sector.This review aims to provide an overview of the impact of ... Cotton is an essential agricultural commodity,but its global yield is greatly affected by climate change,which poses a serious threat to the agriculture sector.This review aims to provide an overview of the impact of climate change on cotton production and the use of genomic approaches to increase stress tolerance in cotton.This paper discusses the effects of rising temperatures,changing precipitation patterns,and extreme weather events on cotton yield.It then explores various genomic strategies,such as genomic selection and marker-assisted selection,which can be used to develop stress-tolerant cotton varieties.The review emphasizes the need for interdisciplinary research efforts and policy interventions to mitigate the adverse effects of climate change on cotton production.Furthermore,this paper presents advanced prospects,including genomic selection,gene editing,multi-omics integration,highthroughput phenotyping,genomic data sharing,climate-informed breeding,and phenomics-assisted genomic selection,for enhancing stress resilience in cotton.Those innovative approaches can assist cotton researchers and breeders in developing highly resilient cotton varieties capable of withstanding the challenges posed by climate change,ensuring the sustainable and prosperous future of cotton production. 展开更多
关键词 COTTON Climate change Stress tolerance Genomic selection Gene editing QTLS Fiber
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饱和压实黄土的Duncan-Chang损伤本构模型研究
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作者 杨皓铭 黄强兵 +3 位作者 解庆禹 崔磊 康孝森 王作辰 《水文地质工程地质》 北大核心 2025年第3期79-90,共12页
黄土地区高铁路基瞬时沉降与饱和压实黄土的力学特性密切相关,饱和压实黄土的本构关系是表征其力学特性的重要途径。由于Duncan-Chang本构模型难以准确描述压实黄土破坏后的应变软化特性,为了提高其适用性,引入统计损伤理论,建立了饱和... 黄土地区高铁路基瞬时沉降与饱和压实黄土的力学特性密切相关,饱和压实黄土的本构关系是表征其力学特性的重要途径。由于Duncan-Chang本构模型难以准确描述压实黄土破坏后的应变软化特性,为了提高其适用性,引入统计损伤理论,建立了饱和压实黄土的Duncan-Chang损伤本构模型。选取西延高铁填方区Qp3黄土,开展了不同压实度的固结不排水三轴试验,编写vumat子程序进行验证,实现了饱和压实黄土三轴试验及不同压实度、不同填方坡度下路基沉降的有限元数值模拟分析。结果表明:(1)填方区压实黄土受剪破坏时呈应变软化特性,峰值强度与初始变形模量随压实度的增加而增加,但峰值强度增幅随压实度增加递减,而初始变形模量增幅随压实度的增加递增;(2)基于统计损伤的DuncanChang本构模型所编写的vumat子程序,对填方压实黄土三轴试验的剪切强度进行了验证,结果基本一致,能够较好地反映填方区压实黄土应变软化的力学特性;(3)通过vumat计算得出,填方路基的沉降量随压实度的增加而减少,随填方坡度的增加而增加。研究结果可为黄土地区填方路基瞬时沉降计算与分析提供参考。 展开更多
关键词 饱和压实黄土 Duncan-chang损伤模型 高铁路基沉降 剪切特性 数值模拟
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Numerical simulation of dynamic Coulomb stress changes induced by M6.5 earthquake in Wuding, Yunnan and its relationship with aftershocks 被引量:6
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作者 虎雄林 吴小平 +3 位作者 杨润海 付虹 胡家富 黄雍 《地震学报》 CSCD 北大核心 2008年第1期26-35,共10页
Based on the discrete wavenumber method, we calculate the fields of dynamic Coulomb rupture stress changes and static stress changes caused by M6.5 earthquake in Wuding, and study their relationship with the subsequen... Based on the discrete wavenumber method, we calculate the fields of dynamic Coulomb rupture stress changes and static stress changes caused by M6.5 earthquake in Wuding, and study their relationship with the subsequent after- shocks. The results show that the spatial distribution patterns of the positive region of dynamic stress peak value and static stress peak value are similarly asymmetric, which are basically identical with distribution features of aftershock. The dynamic stress peak value and the static stress in the positive region are more than 0.1 MPa and 0.01 MPa of the triggering threshold, respectively, which indicates that the dynamic and static stresses are helpful for the occurrence of aftershock. This suggests that both influences of dynamic and static stresses should be con- sidered other than only either of them when studying aftershock triggering in near field. 展开更多
关键词 武定地震 动态库仑破裂应力变化 余震 动态应力触发
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Potential role of ecto-5'-nucleotidase in morphine-induced uridine release and neurobehavioral changes 被引量:1
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作者 CHE Xiao-hang LIU Ping +8 位作者 WU Chun-fu SONG Wu AN Ni-na YU Li-sha BAI Yi-jun XING Zheng CAI Jia-ling WANG Xiao-min YANG Jing-yu 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2018年第9期722-722,共1页
OBJECTIVE There is growing evidence that uridine may act as an endogenous neuromodulator with a potential signaling role in the central nervous system in addition to its function in pyrimidine metabolism.We previously... OBJECTIVE There is growing evidence that uridine may act as an endogenous neuromodulator with a potential signaling role in the central nervous system in addition to its function in pyrimidine metabolism.We previously found that acute morphine treatment significantly increased uridine release in the dorsal striatum of mice,while the mechanism involved in morphine-induced uridine release and the role of uridine in morphine-induced neurobehavioral changes have not been understood.METHODS Uridine release in the dorsal striatum of mice was assessed by in vivo microdialysis coupled with high performance liquid chromatography(HPLC) after morphine treatment.Western blotting and immunofluorescence were used to evaluate the expression of uridine-related proteins.Morphine-induced neurobehavioral changes were assessed by locomotor activity,behavioral sensitization and conditioned place preference(CPP)test.The expression of NT5E,an extracellular enzyme involved in formation of nucleosides,including uridine,was specifically knocked down in the dorsal striatum of mice using adeno-associated virus(AAV)-mediated short hairpin RNA(shRNA).RESULTS Both acute and chronic morphine administration significantly increased uridine release in the dorsal striatum,and this was associated with upregulation of NT5E but not other uridine-related proteins.Inhibition of NT5E with APCP or shRNA markedly inhibited morphine-induced uridine release in the dorsal striatum and related neurobehavioral changes,including hyperlocomotor activity,behavioral sensitization and CPP.CONCLUSION The present study increases our understanding of the contribution of NT5E in regulating morphine-induced neurobehavioral changes,at least as related to uridine,and suggests that NT5E may be a novel therapeutic target to manage morphine abuse. 展开更多
关键词 ecto-5'-nucleotidases URIDINE MORPHINE NEUROBEHAVIORAL changes
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Property changes of anchor grout calcined ginger nuts admixed with fly ash and quartz sand after accelerated ageing tests 被引量:4
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作者 ZHANG Jing-ke ZHANG Li-xiang +3 位作者 ZHAO Lin-yi LIU Dun GUO Qing-lin PEI Qiang-qiang 《Journal of Central South University》 SCIE EI CAS CSCD 2019年第11期3114-3125,共12页
Calcined ginger nuts admixed by fly ash and quartz sand(CGN-(F+S))has been validated to be basically compatible to earthen sites as an anchor grout.Accelerated ageing tests including water stability test,temperature a... Calcined ginger nuts admixed by fly ash and quartz sand(CGN-(F+S))has been validated to be basically compatible to earthen sites as an anchor grout.Accelerated ageing tests including water stability test,temperature and humidity cycling test,soundness test and alkali resistance test are conducted with the objective to further research the property changes of CGN-(F+S)grout.Density,surface hardness,water penetration capacity,water permeability capacity,soluble salt,scanning electron microscopy(SEM)images and energy dispersive spectrometry(EDS)spectrum of these samples have been tested after accelerated ageing tests.The results show that densities of samples decrease,surface hardness,water penetration capacity and water permeability capacity of samples increase generally.Besides,soluble salt analysis,SEM and EDS results well corroborate the changes.Based on the results it can be concluded that property changes are most serious after temperature and humidity cycling test,followed by water stability,soundness and alkali resistance test in sequence.But in general,CGN-(F+S)still has good durability. 展开更多
关键词 CGN-(F+S)grout accelerated ageing tests physical property change chemical property change scanning electron microscopy energy dispersive spectrometry
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ChangeSpider:一个自适应的网页信息跟踪系统 被引量:1
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作者 刘凡 陈康 郑纬民 《计算机工程与应用》 CSCD 北大核心 2003年第34期160-164,共5页
网页信息的更新是网络一个非常重要的性质。同网络的其他应用类似,随着WWW信息内容更新的不断加快,如何有效地跟踪特定网站和页面的更新情况日渐成为人们关心的课题。论文讨论一个自适应的网页信息跟踪系统ChangeSpider,研究其体系结构... 网页信息的更新是网络一个非常重要的性质。同网络的其他应用类似,随着WWW信息内容更新的不断加快,如何有效地跟踪特定网站和页面的更新情况日渐成为人们关心的课题。论文讨论一个自适应的网页信息跟踪系统ChangeSpider,研究其体系结构、关键技术等方面的内容。实验表明ChangeSpider能够有效地跟踪网页的信息变化,及时地将变化的内容提交给用户。 展开更多
关键词 信息更新 更新频率信息采集 信息分发
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Detecting spatio-temporal urban surface changes using identified temporary coherent scatterers 被引量:1
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作者 HU Fengming WU Jicang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2021年第6期1304-1317,共14页
Synthetic aperture radar(SAR) is able to detect surface changes in urban areas with a short revisit time, showing its capability in disaster assessment and urbanization monitoring.Most presented change detection metho... Synthetic aperture radar(SAR) is able to detect surface changes in urban areas with a short revisit time, showing its capability in disaster assessment and urbanization monitoring.Most presented change detection methods are conducted using couples of SAR amplitude images. However, a prior date of surface change is required to select a feasible image pair. We propose an automatic spatio-temporal change detection method by identifying the temporary coherent scatterers. Based on amplitude time series, χ^(2)-test and iterative single pixel change detection are proposed to identify all step-times: the moments of the surface change. Then the parameters, e.g., deformation velocity and relative height, are estimated and corresponding coherent periods are identified by using interferometric phase time series. With identified temporary coherent scatterers, different types of temporal surface changes can be classified using the location of the coherent periods and spatial significant changes are identified combining point density and F values. The main advantage of our method is automatically detecting spatio-temporal surface changes without prior information. Experimental results by the proposed method show that both appearing and disappearing buildings with their step-times are successfully identified and results by ascending and descending SAR images show a good agreement. 展开更多
关键词 change detection temporary coherent scatterer multi-temporal interferometric synthetic aperture radar(InSAR) amplitude analysis
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Investigation of Kiashahr-Dastak Coastline(SW Caspian Sea) Changes Using GIS
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作者 Hossein Bagheri Saeed Khodabakhsh 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期115-115,共1页
In this research,geological and hydrodynamic induced changes in the Kiashahr-Dastak coastal zone (SW Caspian Sea)were investigated based on aerial photographs(1967 and 1993)and ETM satellite images(2002)of the region ... In this research,geological and hydrodynamic induced changes in the Kiashahr-Dastak coastal zone (SW Caspian Sea)were investigated based on aerial photographs(1967 and 1993)and ETM satellite images(2002)of the region utilizing GIS based softwares.The results were represented as erosional and sedimenttation maps during this time spam.GIS based studies and field investigations show that 展开更多
关键词 Caspian SEA level changes EROSION and SEDIMENTATION Kiashahr-Dastak
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Assessment on Temperature Changes of China During the Past 2000 Years
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作者 Zhixin Hao,Quansheng Ge,Jingyun Zheng,Xuemei Shao Institute of Geographic Sciences and Natural Resources Research,Chinese Academy of Sciences,Beijing 100029,China. 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期98-99,共2页
The Fourth Assessment Report of IPCC(IPCC AR4)concluded that average Northern Hemisphere temperatures during the second half of the 20th century were very likely higher than that of any other 50-year period in the las... The Fourth Assessment Report of IPCC(IPCC AR4)concluded that average Northern Hemisphere temperatures during the second half of the 20th century were very likely higher than that of any other 50-year period in the last 500 years and likely the highest in at least the past 1300 years.However,after evaluating Global or Northern Hemisphere temperature change series derived from ice cores,tree rings, 展开更多
关键词 CLIMATE changE China PAST 2000 YEARS MULTI-PROXY data
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Impact of Global Climatic and Environmental Changes on Agricultural Research Challenges and Wheat Productivity in Pakistan
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作者 Ijaz Rasool Noorka Muhammad Afzal 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期100-100,共1页
Food security is a human right,within a global context by aligning the opportunities to eliminate poverty,to attain the peace,the rational and implications of sustainable use and judicious management of natural resour... Food security is a human right,within a global context by aligning the opportunities to eliminate poverty,to attain the peace,the rational and implications of sustainable use and judicious management of natural resources,are the road map,to combat the disasters.The prevailing International tension with respect to climate change suggests that the food security can be achieved by penetrating,in depth,the agricultural research.Pakistan is under threat to 展开更多
关键词 FOOD security POVERTY judicious management SUSTAINABLE CLIMATE change
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Dynamic Changes of Microbial Community for Degradation of Lignocellulose
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作者 LI Wenzhe LIU Shuang WANG Chunying ZHENG Guoxiang 《Journal of Northeast Agricultural University(English Edition)》 CAS 2010年第4期60-65,共6页
Dynamic changes of a microbial community for lignocellulose degradation were explored in details. Community composition and development were investigated by the means of denaturing gradient gel electrophoresis (DGGE... Dynamic changes of a microbial community for lignocellulose degradation were explored in details. Community composition and development were investigated by the means of denaturing gradient gel electrophoresis (DGGE), and results showed that the microbial community was constituted of 14 kinds of bacteria and presented the fluctuation in some degrees with fermentation. Furthmore, the result of cluster analysis of DGGE pattern was accordant with growth curve, and the degradation process was divided into three stages: initial stage (0-12 h), intermediate stage (24-144 h) and end stage (144-216 h). 展开更多
关键词 LIGNOCELLULOSE microbial community dynamic change
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Interlinkage Between Global Environmental Changes,Water Resources Availability and Quality in the East African Rift:Preliminary Analyses and Some Cases:The MaWARi Project(Kenya,Ethiopia,Djibouti,France)
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作者 Kebede Seifu 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期36-37,共2页
The East African Rift extending across Djibouti, Ethiopia and Kenya is characterized by low level of economic development,high level of poverty,increasing population,scarce natural resources(land,water, and environmen... The East African Rift extending across Djibouti, Ethiopia and Kenya is characterized by low level of economic development,high level of poverty,increasing population,scarce natural resources(land,water, and environment),complex and rich ecosystems, increasing desertification and degrading biodiversity, underdeveloped regional trade and market,water resources mainly stored in groundwater and 展开更多
关键词 East AFRICAN RIFT groundwater resources water AVAILABILITY global environmental change impacts SCIENTIFIC regional cooperation
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Analysis of Temporal Changes in Botanical Composition of a Long-term Grazing Experiment in Nixinasuno, Japan
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作者 YIRu-han MASAEShiyomi +1 位作者 SHIGEOTakahashi TADAKATSUOkubo 《Journal of Northeast Agricultural University(English Edition)》 CAS 2004年第1期47-51,共5页
In order to understand the temporal changes of botanical composition in grassland ecosystem, and to clarify the relation between these changes and environmental impacts, such as climatic factors and artificial disturb... In order to understand the temporal changes of botanical composition in grassland ecosystem, and to clarify the relation between these changes and environmental impacts, such as climatic factors and artificial disturbance, a grazing trail was carried out during a 21-year period from 1974 at a sown grassland of the National Grassland Research Institute, located in Nishinasuno, the central area of Japan. The data sets of biomass for each mouth(from April to November)of the 21 year period were analyzed in this paper. The botanical composition of aboveground biomass varied greatly with both season and year. The biomass ratio of improved herbage species to invaded native plants gradually decreased each year. This may have been owing to meteorological factors, such as low air-temperature in winter, dry and hot summers, grassland management(including grazing intensity and fertilizer application), and inter-specific competition between native and introduced herbage plants. 展开更多
关键词 botanical composition grazing intensity grazing pasture temporal change nitrogen application
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基于统计损伤修正的冻结砂—黏混合土改进Duncan-Chang模型
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作者 滕振超 李正巍 +7 位作者 刘佳琳 周亚东 李波 刘彦峰 池林林 张圣童 刘博 计静 《东北石油大学学报》 CAS 北大核心 2024年第2期116-124,I0008,共10页
为描述冻结砂—黏混合土的偏应力—应变关系,进行不同含砂量冻结砂—黏混合土的冻土三轴压缩试验。基于改进的Duncan-Chang模型(D-C模型),引入统计损伤理论,拟合三轴压缩试验结果,分别建立以Mises强度准则和应变发展为微元强度变量的统... 为描述冻结砂—黏混合土的偏应力—应变关系,进行不同含砂量冻结砂—黏混合土的冻土三轴压缩试验。基于改进的Duncan-Chang模型(D-C模型),引入统计损伤理论,拟合三轴压缩试验结果,分别建立以Mises强度准则和应变发展为微元强度变量的统计损伤修正模型,对比计算结果与试验数据。结果表明:冻结砂—黏混合土偏应力峰值随含砂量的增加而增加,偏应力—应变曲线由应变硬化型逐渐过渡到应变软化型的临界含砂量为50%。当含砂量介于20%~60%时,基于统计损伤理论的修正改进D-C模型能有效拟合应变硬化型曲线和具有轻微应变软化现象的偏应力—应变曲线。当含砂量为90%时,基于应变发展的统计损伤修正模型的偏应力峰值与试验结果相差3%,具有较强适用性。该结果为不同微元强度变量的统计损伤修正模型提供参考。 展开更多
关键词 冻结砂—黏混合土 三轴压缩试验 改进Duncan-chang模型 统计损伤理论 应变软化模型
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Two new approaches for image registration based onspatial-temporal relationship
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作者 DengZhipeng YangJie LiuXiaojun 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2005年第2期284-289,共6页
How to improve the probability of registration and precision of localization is a hard problem, which is desiderated to solve. The two basic approaches (normalized cross-correlation and phase correlation) for image re... How to improve the probability of registration and precision of localization is a hard problem, which is desiderated to solve. The two basic approaches (normalized cross-correlation and phase correlation) for image registration are analysed, two improved approaches based on spatial-temporal relationship are presented. This method adds the correlation matrix according to the displacements in x- cirection and y- directions, and the registration pose is searched in the added matrix. The method overcomes the shortcoming that the probability of registration decreasing with area increasing owing to geometric distortion, improves the probability and the robustness of registration. 展开更多
关键词 image registration phase correlation normalized cross-correlation spatial-temporal relationship.
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Immunological Changes of Chicks Immunized with March's Disease Vaccines and Challenged with Virulent MD Virus
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作者 Liu Zhonggui Gao Rong +4 位作者 Li Qingzhang Zheng Shimin Liu Yun Yang Liping(Northeast Agricultural University, Harbin 1 50030, P R C) 《Journal of Northeast Agricultural University(English Edition)》 CAS 1995年第1期45-54,共10页
The experiment was conducted to inoculate one-day old chicks with March's disease (MD) trivalent and herpesvirus of turkey (HVT) vaccines separately, and then to challenge them with virulent MD virus (vMDV) at the... The experiment was conducted to inoculate one-day old chicks with March's disease (MD) trivalent and herpesvirus of turkey (HVT) vaccines separately, and then to challenge them with virulent MD virus (vMDV) at the age of 15 days. and 5, 25, 45 and 75 days after the challenge with vMDV, comparing with the control-challenged chicks without immunization, to detect the immunoprotetive efficacy and dynamic changes of the inductive activity of interleukin-2(IL-2), expression of IL-2 receptor and proliferative function of T cells in thymus and spleen; the number of ANAE+T, AP+T cells and IgG, IgM, IgA antibody-producing cells in Bursa Fabricius, spleen,thymus, cecal tonsil and Harder gland; as the amount of T cells and IgG, IgM, IgA in peripheral blood as well as the content of IgG, IgM and IgA in the tear, trachea washings, bile and intestinal fluids of the experimental chicks. The experimental results firstly demonstrate that the immunorcgulation of IL-2, and IL-2 receptor, the cellualr and humoral immune responses were significantly enhanced in the central and peripheral immune organs; the local mucosal immune function were markedly amplified in the respiratory and digestive tracts of the immunized-challenged,chicks, which were closely correlated with the immunoprotection against MD; the immune response and immunoprotective effect of the trivalent vaccine-immunized chicks were much better than those of HVT vaccine-immunized chicks: 展开更多
关键词 CHICKS Tnoculation with March's disease vaceines challenge with virulent MD virus immunological changes
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Effect of volume changes on complete deformation behavior of rocks
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作者 赵衡 曹文贵 +1 位作者 李翔 张玲 《Journal of Central South University》 SCIE EI CAS 2010年第2期394-399,共6页
For the purpose of describing the deformation characteristics of rocks,the effect of volume changes on mechanical properties of rocks should be taken into account with relation to the development of constitutive model... For the purpose of describing the deformation characteristics of rocks,the effect of volume changes on mechanical properties of rocks should be taken into account with relation to the development of constitutive model.Firstly,rocks are divided into three parts,i.e.,voids,a damaged part and an undamaged part in the course of loading.The void ratio was applied to describing the changes of voids or pores during the deformation process.Then,using statistical damage theory,a constitutive model was developed for rocks to describe their strain softening and hardening on the basis of investigating the relationship between the net stress and apparent stress,in which the influence of volume changes on rock behavior was correctly taken into account,such as the initial phase of compaction and the latter stage of dilation.Thirdly,a method of determining model parameters was also presented.Finally,this model was used to compare the theoretical results with those observed from experiments under conventional triaxial loading conditions. 展开更多
关键词 rock mechanics constitutive model statistical damage theory volume change void ratio
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Changes and Development of Home and Community Based Elderly Care Service Policies in China
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作者 Wu Li 《学术界》 CSSCI 北大核心 2020年第8期226-233,共8页
This paper analyzes the current situation of the development of home and community based elderly care service in China,points out the existing problems,and puts forward improvement measures,aiming to deepen the unders... This paper analyzes the current situation of the development of home and community based elderly care service in China,points out the existing problems,and puts forward improvement measures,aiming to deepen the understanding of HCBS and promote the theoretical research and practice of community home-based elderly care service. 展开更多
关键词 home and community based elderly care service policy change DEVELOPMENT
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