柑橘作为世界上重要经济作物之一,随着生产规模的扩大,病虫害日益成为制约其发展的瓶颈。在为害柑橘的众多害虫中,柑橘木虱Diaphorina citri Kuwayama为害最为严重,其成虫和若虫不仅能直接刺吸为害柑橘、柠檬等芸香科植物,还是传播柑橘...柑橘作为世界上重要经济作物之一,随着生产规模的扩大,病虫害日益成为制约其发展的瓶颈。在为害柑橘的众多害虫中,柑橘木虱Diaphorina citri Kuwayama为害最为严重,其成虫和若虫不仅能直接刺吸为害柑橘、柠檬等芸香科植物,还是传播柑橘黄龙病(Huanglongbing,HLB)的重要媒介。“Push-Pull”策略作为害虫生态调控(Ecological regulation and management of pests,ERMP)中的一项重要技术,具有“经济、简便、有效、绿色”等优点。通过推广普及“Push-Pull”技术,将有助于控制柑橘木虱的为害,推动我国柑橘产业绿色发展。本文以综述“Push-Pull”策略为例,分别介绍了“Push”和“Pull”两个组分的研究进展,展望“Push-Pull”策略在防治柑橘木虱的发展应用,希望能为柑橘生产过程中经济、简便、有效地治理柑橘木虱提供理论参考和技术支撑,推动我国柑橘产业健康可持续发展。展开更多
Energetic compounds bearing the trinitromethyl group are garnering broad attraction as potential candidates for a new generation of high energy dense oxidizers.In this work,an effective dual modulation strategy involv...Energetic compounds bearing the trinitromethyl group are garnering broad attraction as potential candidates for a new generation of high energy dense oxidizers.In this work,an effective dual modulation strategy involving both molecular isomerization and crystal morphology control was employed to design and optimize trinitromethyl-oxadiazole with improved comprehensive performance.Utilizing this dual strategy,3,5-bis(trinitromethyl)-1,2,4-oxadiazole(3)was synthesized,resulting in the formation of two distinct crystal morphologies(needle and sheet)corresponding to two crystal forms(3-a and3-b).Encouragingly,while maintaining ultra-high oxygen balance(21.73%),3 achieves impressive densities(1.97-1.98 g/cm^(3)).To our knowledge,the density of 1.98 g/cm^(3)for 3-a sets a new record among that of nitrogen-rich monocyclic compounds.Notably,practical crystal morphology prediction was creatively introduced to guide the experimental crystallization conditions of 3,increasing the impact sensitivity and friction sensitivity from 1 J to 80 N(3-a)to 10 J and 240 N(3-b),respectively.Additionally,the crystal structural analyses and theoretical calculations were conducted to elucidate the reasons of differences between 3-a and 3-b in density and stability.This work provides an efficient strategy to enhance performance of trinitromethyl derivatives,broadening the path and expanding the toolbox for energetic materials.展开更多
In low Earth orbit(LEO)satellite networks,on-board energy resources of each satellite are extremely limited.And with the increase of the node number and the traffic transmis-sion pressure,the energy consumption in the...In low Earth orbit(LEO)satellite networks,on-board energy resources of each satellite are extremely limited.And with the increase of the node number and the traffic transmis-sion pressure,the energy consumption in the networks presents uneven distribution.To achieve energy balance in networks,an energy consumption balancing optimization algorithm of LEO networks based on distance energy factor(DEF)is proposed.The DEF is defined as the function of the inter-satellite link dis-tance and the cumulative network energy consumption ratio.According to the minimum sum of DEF on inter-satellite links,an energy consumption balancing algorithm based on DEF is pro-posed,which can realize dynamic traffic transmission optimiza-tion of multiple traffic services.It can effectively reduce the energy consumption pressure of core nodes with high energy consumption in the network,make full use of idle nodes with low energy consumption,and optimize the energy consumption dis-tribution of the whole network according to the continuous itera-tions of each traffic service flow.Simulation results show that,compared with the traditional shortest path algorithm,the pro-posed method can improve the balancing performance of nodes by 75%under certain traffic pressure,and realize the optimiza-tion of energy consumption balancing of the whole network.展开更多
The size of impeller reflux holes for centrifugal pump has influence on the pressure distribution of front and rear shrouds and rear pump chamber, as well as energy characteristics of whole pump and axial force. Low s...The size of impeller reflux holes for centrifugal pump has influence on the pressure distribution of front and rear shrouds and rear pump chamber, as well as energy characteristics of whole pump and axial force. Low specific-speed centrifugal pump with Q=12.5 m3/h, H=60 m, n=2950 r/min was selected to be designed with eight axial reflux balance holes with 4.5 mm in diameter. The simulated Q-H curve and net positive suction head(NPSH) were in good agreement with experimental results, which illustrated that centrifugal pump with axial reflux balance holes was superior in the cavitation characteristic; however, it showed to little superiority in head and efficiency. The pressure in rear pump chamber at 0.6 times rate flow is 29.36% of pressure difference between outlet and inlet, which reduces to 29.10% at rate flow and 28.33% at 1.4 times rate flow. As the whole, the pressure distribution on front and rear shrouds from simulation results is not a standard parabola, and axial force decreases as flow rate increases. Radical reflux balance holes chosen to be 5.2 mm and 5.9 mm in diameter were further designed with other hydraulic parts unchanged. With structural grids adopted for total flow field, contrast numerical simulation on internal flow characteristics was conducted based on momentum equations and standard turbulence model(κ-ε). It is found that axial force of pump with radical reflux balance holes of5.2 mm and 5.9 mm in diameter is significantly less than that with radical reflux balance holes of 4.5 mm in diameter. Better axial force balance is obtained as the ratio of area of reflux balance holes and area of sealing ring exceeds 6.展开更多
The Qaidam Basin,located in the northern margin of the Qinghai-Tibet Plateau,is a large Mesozoic -Cenozoic basin,and bears huge thick Cenozoic strata.The geologic events of the Indian-Eurasian plate-plate collision si...The Qaidam Basin,located in the northern margin of the Qinghai-Tibet Plateau,is a large Mesozoic -Cenozoic basin,and bears huge thick Cenozoic strata.The geologic events of the Indian-Eurasian plate-plate collision since～55 Ma have been well recorded.Based on the latest progress in high-resolution stratigraphy,a technique of balanced section was applied to six pieces of northeast-southwest geologic seismic profiles in the central and eastern of the Qaidam Basin to reconstruct the crustal shortening deformation history during the Cenozoic collision. The results show that the Qaidam Basin began展开更多
To improve the energy utilization efficiency of internal combustion （IC） engine, exergy analysis was conducted on a passenger car gasoline engine. According to the thermodynamic theory of IC engine, in-cylinder exer...To improve the energy utilization efficiency of internal combustion （IC） engine, exergy analysis was conducted on a passenger car gasoline engine. According to the thermodynamic theory of IC engine, in-cylinder exergy balance model was built. The working processes of gasoline engine were simulated by using the GT-power. In this way, the required parameters were calculated and then gasoline engine exergy balance was obtained by programming on computer. On this basis, the influences of various parameters on exergy balance were analyzed. Results show that, the proportions of various forms of exergy in gasoline engine from high to low are irreversible loss, effective work, exhaust gas exergy and heat transfer exergy. Effective exergy proportion fluctuates with cylinder volumetric efficiency at full load, while it always increases with break mean effective pressure （BMEP） at part load. Exhaust gas exergy proportion is more sensitive to speed, and it increases with speed increasing except at the highest speed. The lower proportion of heat transfer exergy appears at high speed and high load. Irreversible loss is mainly influenced by load. At part load, higher BMEP results in lower proportion of irreversible loss; at full load, the proportion of irreversible loss changes little except at the highest speed.展开更多
Geological studies indicate that Qinghai\|Tibet plateau crust has shortened at least 2500km and the thickness was increased to 60～70km in the past 45Ma. Different researchers advocate different views to explain the s...Geological studies indicate that Qinghai\|Tibet plateau crust has shortened at least 2500km and the thickness was increased to 60～70km in the past 45Ma. Different researchers advocate different views to explain the shortening according to their studies.( Tapponnier,1977;Chang et al,1986;England et al,1986;Murphy,1997;Y.Pan,1999),however it is still unresolved on how much shortening in upper crustal especially in Qiangtang terrain.Qiangtang terrain is located in the center of Qinghai\|Tibet plateau, the tectonic deformation has been resulted from intracontinental convergence and collision of India plate with Eurasian plate.The deformation style of Qiangtang terrain shows east\|west\|trending folds and thrusts which formed in the shallow tectonic level during collisional\|intracontinental period. The folds type is characterized by nonpenetrative\|foliation parallel fold, the hinges have the same trend with the thrusts. These traits are favourable for restoring the balanced cross\|section and measuring the shortening. The balanced reconstruction is based on line balancing on three different stratigraphic sections (A,B and C)across the Northern Qiangtang basin in the area between 85°E and 87°E.The sections are all north\|south\|trending in accordance with the moving direction of thrusts.展开更多
OBJECTIVE Atherosclerosis(AS)is a chronic inflammatory disease characterized by the accumulation of lipids,vascular fibrosis,and inflammation.Paeonol(Pae)is a natural phenolic compounds isolated from a traditional Chi...OBJECTIVE Atherosclerosis(AS)is a chronic inflammatory disease characterized by the accumulation of lipids,vascular fibrosis,and inflammation.Paeonol(Pae)is a natural phenolic compounds isolated from a traditional Chinese medicine,Cortex Moutan,which exhibits anti-AS effects.Our previous work demonstrated that gut microbiota plays an important role during AS treatment as it affects the efficacy of Pae.However,the mechanism of Pae in protecting against vascular fibrosis as related to gut microbiota has yet to be elucidated.To investigate the anti-fibrosis effect of Pae on AS mice and demonstrate the underlying gut microbiota-dependent mechanism.METHODS ApoE-/-mice were fed with high-fat-diet(HFD)to replicate the AS model.HE and Masson staining were used to observe the plaque formation and collagen deposition.Gut microbiota alteration and short-chain fatty acids(SCFAs)production were analyzed through 16S rRNA sequencing and LC-MS/MS.The frequency of immune cells in spleen were phenotyped by flow cytometry.The mRNA expression of aortic inflammatory cytokines were detected by qRT-PCR.The protein expression of LOX and fibrosis related indicators were examined by Western blotting.RESULTS Pae restricted the development of AS and collagen deposition.Notably,the anti-fibrosis effect of Pae was achieved by regulating the gut microbiota.16S rRNA sequencing and LC-MS/MS data indicated that the relative abundance of SCFAs-producing bacteria and SCFAs production was increased.Additionally,Pae administration selectively up-regulated the frequency of regulatory T(Treg)cells as well as down-regulated the ratio of T helper type 17(Th17)cells in the spleen of AS mice,improving the Treg/Th17 balance.In addition,as expected,Pae intervention significantly down-regulate the mRNA expression levels of pro-inflammatory cytokines IL^(-1)β,IL-6,TNF-αand IL^(-1)7 in the aorta tissue,up-regulate the levels of anti-inflammatory factor IL^(-1)0,a marker of Treg cells.Finally,Pae′s intervention in the gut microbiota resulted in the restoration of the balance of Treg/Th17,which indirectly down-regulated the protein expression level of LOX and fibrosis-related indicators(MMP-2/9 and collagenⅠ/Ⅲ).CONCLUSION Pae attenuates vascular fibrosis in a gut microbiota-dependent manner.The underlying protective mechanism is associated with the improved Treg/Th17 balance in spleen mediated through the increased microbiota-derived SCFAs production.展开更多
Cantilever casting concrete arch bridge using form traveller has a broad application prospect.However,it is difficult to obtain reasonable initial cable force in construction stage.In this study,stress balance and inf...Cantilever casting concrete arch bridge using form traveller has a broad application prospect.However,it is difficult to obtain reasonable initial cable force in construction stage.In this study,stress balance and influence matrix methods were developed to determine the initial cable force of cantilever casting concrete arch bridge.The stress balance equation and influence matrix of arch rib critical section were established,and the buckle cable force range was determined by the allowable stress of arch rib critical section.Then a group of buckle cable forces were selected and substituted into the stress balance equation,and the reasonable initial buckle cable force was determined through iteration.Based on the principle of force balance,the initial anchor cable force was determined.In an engineering application example,it is shown that the stress balance and influence matrix methods for the determination of initial cable force are feasible and reliable.The initial cable forces of arch rib segments only need to be adjusted once in the corresponding construction process,which improves the working efficiency and reduces the construction risk.It is found that the methods have great advantages for determining initial cable force in cantilever casting construction process of concrete arch bridge.展开更多
The discrete element method (DEM) was used to simulate the flow characteristic and strength characteristic of the conditioned sands in the earth pressure balance (EPB) tunneling. In the laboratory the conditioned sand...The discrete element method (DEM) was used to simulate the flow characteristic and strength characteristic of the conditioned sands in the earth pressure balance (EPB) tunneling. In the laboratory the conditioned sands were reproduced and the slump test and the direct shear test of the conditioned sands were implemented. A DEM equivalent model that can simulate the macro mechanical characteristic of the conditioned sands was proposed,and the corresponding numerical models of the slump test and the shear test were established. By selecting proper DEM model parameters,the errors of the slump values between the simulation results and the test results are in the range of 10.3%-14.3%,and the error of the curves between the shear displacement and the shear stress calculated with the DEM simulation is 4.68%-16.5% compared with that of the laboratory direct shear test. This illustrates that the proposed DEM equivalent model can approximately simulate the mechanical characteristics of the conditioned sands,which provides the basis for further simulation of the interaction between the conditioned soil and the chamber pressure system of the EPB machine.展开更多
In order to exactly provide scientific basis for pressure dynamic balance control of working chamber of earth pressure balance shield (EPBS),study on optimal arrangement of pressure measurement points in working chamb...In order to exactly provide scientific basis for pressure dynamic balance control of working chamber of earth pressure balance shield (EPBS),study on optimal arrangement of pressure measurement points in working chamber was conducted. Based on mathematical description of optimal arrangement for pressure measurement points,fuzzy clustering analysis and discriminant analysis were used to divide pressure regions of nodes on bulkhead. Finally,the selection method of optimal measurement points was proposed,and by selecting d6.28 m EPBS as study object,the case study was conducted. By contrast,based on optimal arrangement scheme of pressure measurement points,through adopting weighted algorithm,the absolute error mean of equivalent pressure of working chamber is the smallest. In addition,pressure curve of optimal arrangement points presents parabola,and it can show the state of pressure distribution on bulkhead truly. It is concluded that the optimal arrangement method of pressure measurement points in working chamber is effective and feasible,and the method can provide basis for realizing high precision pressure control of EPBS.展开更多
文摘柑橘作为世界上重要经济作物之一,随着生产规模的扩大,病虫害日益成为制约其发展的瓶颈。在为害柑橘的众多害虫中,柑橘木虱Diaphorina citri Kuwayama为害最为严重,其成虫和若虫不仅能直接刺吸为害柑橘、柠檬等芸香科植物,还是传播柑橘黄龙病(Huanglongbing,HLB)的重要媒介。“Push-Pull”策略作为害虫生态调控(Ecological regulation and management of pests,ERMP)中的一项重要技术,具有“经济、简便、有效、绿色”等优点。通过推广普及“Push-Pull”技术,将有助于控制柑橘木虱的为害,推动我国柑橘产业绿色发展。本文以综述“Push-Pull”策略为例,分别介绍了“Push”和“Pull”两个组分的研究进展,展望“Push-Pull”策略在防治柑橘木虱的发展应用,希望能为柑橘生产过程中经济、简便、有效地治理柑橘木虱提供理论参考和技术支撑,推动我国柑橘产业健康可持续发展。
基金supported by the National Natural Science Foundation of China(No.22375021,22235003,22261132516&22205021)the BIT Research and Innovation 265 Promoting Project(Grant No.2023YCXZ017)。
文摘Energetic compounds bearing the trinitromethyl group are garnering broad attraction as potential candidates for a new generation of high energy dense oxidizers.In this work,an effective dual modulation strategy involving both molecular isomerization and crystal morphology control was employed to design and optimize trinitromethyl-oxadiazole with improved comprehensive performance.Utilizing this dual strategy,3,5-bis(trinitromethyl)-1,2,4-oxadiazole(3)was synthesized,resulting in the formation of two distinct crystal morphologies(needle and sheet)corresponding to two crystal forms(3-a and3-b).Encouragingly,while maintaining ultra-high oxygen balance(21.73%),3 achieves impressive densities(1.97-1.98 g/cm^(3)).To our knowledge,the density of 1.98 g/cm^(3)for 3-a sets a new record among that of nitrogen-rich monocyclic compounds.Notably,practical crystal morphology prediction was creatively introduced to guide the experimental crystallization conditions of 3,increasing the impact sensitivity and friction sensitivity from 1 J to 80 N(3-a)to 10 J and 240 N(3-b),respectively.Additionally,the crystal structural analyses and theoretical calculations were conducted to elucidate the reasons of differences between 3-a and 3-b in density and stability.This work provides an efficient strategy to enhance performance of trinitromethyl derivatives,broadening the path and expanding the toolbox for energetic materials.
基金supported by the National Key Research and Development Program(2021YFB2900604).
文摘In low Earth orbit(LEO)satellite networks,on-board energy resources of each satellite are extremely limited.And with the increase of the node number and the traffic transmis-sion pressure,the energy consumption in the networks presents uneven distribution.To achieve energy balance in networks,an energy consumption balancing optimization algorithm of LEO networks based on distance energy factor(DEF)is proposed.The DEF is defined as the function of the inter-satellite link dis-tance and the cumulative network energy consumption ratio.According to the minimum sum of DEF on inter-satellite links,an energy consumption balancing algorithm based on DEF is pro-posed,which can realize dynamic traffic transmission optimiza-tion of multiple traffic services.It can effectively reduce the energy consumption pressure of core nodes with high energy consumption in the network,make full use of idle nodes with low energy consumption,and optimize the energy consumption dis-tribution of the whole network according to the continuous itera-tions of each traffic service flow.Simulation results show that,compared with the traditional shortest path algorithm,the pro-posed method can improve the balancing performance of nodes by 75%under certain traffic pressure,and realize the optimiza-tion of energy consumption balancing of the whole network.
基金Project(51179075)supported by the National Natural Science Foundation of ChinaProject(BK20131256)supported by the Natural Science Funds of Jiangsu Province,ChinaProject supported by the Priority Academic Program Development of Jiangsu High Education Institutions,China
文摘The size of impeller reflux holes for centrifugal pump has influence on the pressure distribution of front and rear shrouds and rear pump chamber, as well as energy characteristics of whole pump and axial force. Low specific-speed centrifugal pump with Q=12.5 m3/h, H=60 m, n=2950 r/min was selected to be designed with eight axial reflux balance holes with 4.5 mm in diameter. The simulated Q-H curve and net positive suction head(NPSH) were in good agreement with experimental results, which illustrated that centrifugal pump with axial reflux balance holes was superior in the cavitation characteristic; however, it showed to little superiority in head and efficiency. The pressure in rear pump chamber at 0.6 times rate flow is 29.36% of pressure difference between outlet and inlet, which reduces to 29.10% at rate flow and 28.33% at 1.4 times rate flow. As the whole, the pressure distribution on front and rear shrouds from simulation results is not a standard parabola, and axial force decreases as flow rate increases. Radical reflux balance holes chosen to be 5.2 mm and 5.9 mm in diameter were further designed with other hydraulic parts unchanged. With structural grids adopted for total flow field, contrast numerical simulation on internal flow characteristics was conducted based on momentum equations and standard turbulence model(κ-ε). It is found that axial force of pump with radical reflux balance holes of5.2 mm and 5.9 mm in diameter is significantly less than that with radical reflux balance holes of 4.5 mm in diameter. Better axial force balance is obtained as the ratio of area of reflux balance holes and area of sealing ring exceeds 6.
文摘The Qaidam Basin,located in the northern margin of the Qinghai-Tibet Plateau,is a large Mesozoic -Cenozoic basin,and bears huge thick Cenozoic strata.The geologic events of the Indian-Eurasian plate-plate collision since～55 Ma have been well recorded.Based on the latest progress in high-resolution stratigraphy,a technique of balanced section was applied to six pieces of northeast-southwest geologic seismic profiles in the central and eastern of the Qaidam Basin to reconstruct the crustal shortening deformation history during the Cenozoic collision. The results show that the Qaidam Basin began
基金Foundation item： Project（2011CB707201） supported by the National Basic Research Program of China Project（10JJ5058） supported by the Natural Science Foundation of Hunan Province, China
文摘To improve the energy utilization efficiency of internal combustion （IC） engine, exergy analysis was conducted on a passenger car gasoline engine. According to the thermodynamic theory of IC engine, in-cylinder exergy balance model was built. The working processes of gasoline engine were simulated by using the GT-power. In this way, the required parameters were calculated and then gasoline engine exergy balance was obtained by programming on computer. On this basis, the influences of various parameters on exergy balance were analyzed. Results show that, the proportions of various forms of exergy in gasoline engine from high to low are irreversible loss, effective work, exhaust gas exergy and heat transfer exergy. Effective exergy proportion fluctuates with cylinder volumetric efficiency at full load, while it always increases with break mean effective pressure （BMEP） at part load. Exhaust gas exergy proportion is more sensitive to speed, and it increases with speed increasing except at the highest speed. The lower proportion of heat transfer exergy appears at high speed and high load. Irreversible loss is mainly influenced by load. At part load, higher BMEP results in lower proportion of irreversible loss; at full load, the proportion of irreversible loss changes little except at the highest speed.
文摘Geological studies indicate that Qinghai\|Tibet plateau crust has shortened at least 2500km and the thickness was increased to 60～70km in the past 45Ma. Different researchers advocate different views to explain the shortening according to their studies.( Tapponnier,1977;Chang et al,1986;England et al,1986;Murphy,1997;Y.Pan,1999),however it is still unresolved on how much shortening in upper crustal especially in Qiangtang terrain.Qiangtang terrain is located in the center of Qinghai\|Tibet plateau, the tectonic deformation has been resulted from intracontinental convergence and collision of India plate with Eurasian plate.The deformation style of Qiangtang terrain shows east\|west\|trending folds and thrusts which formed in the shallow tectonic level during collisional\|intracontinental period. The folds type is characterized by nonpenetrative\|foliation parallel fold, the hinges have the same trend with the thrusts. These traits are favourable for restoring the balanced cross\|section and measuring the shortening. The balanced reconstruction is based on line balancing on three different stratigraphic sections (A,B and C)across the Northern Qiangtang basin in the area between 85°E and 87°E.The sections are all north\|south\|trending in accordance with the moving direction of thrusts.
基金National Natural Science Foundation of China(81773937)。
文摘OBJECTIVE Atherosclerosis(AS)is a chronic inflammatory disease characterized by the accumulation of lipids,vascular fibrosis,and inflammation.Paeonol(Pae)is a natural phenolic compounds isolated from a traditional Chinese medicine,Cortex Moutan,which exhibits anti-AS effects.Our previous work demonstrated that gut microbiota plays an important role during AS treatment as it affects the efficacy of Pae.However,the mechanism of Pae in protecting against vascular fibrosis as related to gut microbiota has yet to be elucidated.To investigate the anti-fibrosis effect of Pae on AS mice and demonstrate the underlying gut microbiota-dependent mechanism.METHODS ApoE-/-mice were fed with high-fat-diet(HFD)to replicate the AS model.HE and Masson staining were used to observe the plaque formation and collagen deposition.Gut microbiota alteration and short-chain fatty acids(SCFAs)production were analyzed through 16S rRNA sequencing and LC-MS/MS.The frequency of immune cells in spleen were phenotyped by flow cytometry.The mRNA expression of aortic inflammatory cytokines were detected by qRT-PCR.The protein expression of LOX and fibrosis related indicators were examined by Western blotting.RESULTS Pae restricted the development of AS and collagen deposition.Notably,the anti-fibrosis effect of Pae was achieved by regulating the gut microbiota.16S rRNA sequencing and LC-MS/MS data indicated that the relative abundance of SCFAs-producing bacteria and SCFAs production was increased.Additionally,Pae administration selectively up-regulated the frequency of regulatory T(Treg)cells as well as down-regulated the ratio of T helper type 17(Th17)cells in the spleen of AS mice,improving the Treg/Th17 balance.In addition,as expected,Pae intervention significantly down-regulate the mRNA expression levels of pro-inflammatory cytokines IL^(-1)β,IL-6,TNF-αand IL^(-1)7 in the aorta tissue,up-regulate the levels of anti-inflammatory factor IL^(-1)0,a marker of Treg cells.Finally,Pae′s intervention in the gut microbiota resulted in the restoration of the balance of Treg/Th17,which indirectly down-regulated the protein expression level of LOX and fibrosis-related indicators(MMP-2/9 and collagenⅠ/Ⅲ).CONCLUSION Pae attenuates vascular fibrosis in a gut microbiota-dependent manner.The underlying protective mechanism is associated with the improved Treg/Th17 balance in spleen mediated through the increased microbiota-derived SCFAs production.
基金Projects(51478049,51778068)supported by the National Natural Science Foundation of ChinaProject(14JJ2075,2019JJ40301)supported by the Hunan Natural Science Foundation of China+1 种基金Project(17A010)supported by the Scientific Research Fund of Hunan Provincial Education Department of ChinaProject(2017GK4034)supported by the Major Technological Achievements Transformation Program of Hunan Strategic Emerging Industries of China
文摘Cantilever casting concrete arch bridge using form traveller has a broad application prospect.However,it is difficult to obtain reasonable initial cable force in construction stage.In this study,stress balance and influence matrix methods were developed to determine the initial cable force of cantilever casting concrete arch bridge.The stress balance equation and influence matrix of arch rib critical section were established,and the buckle cable force range was determined by the allowable stress of arch rib critical section.Then a group of buckle cable forces were selected and substituted into the stress balance equation,and the reasonable initial buckle cable force was determined through iteration.Based on the principle of force balance,the initial anchor cable force was determined.In an engineering application example,it is shown that the stress balance and influence matrix methods for the determination of initial cable force are feasible and reliable.The initial cable forces of arch rib segments only need to be adjusted once in the corresponding construction process,which improves the working efficiency and reduces the construction risk.It is found that the methods have great advantages for determining initial cable force in cantilever casting construction process of concrete arch bridge.
基金Project (2007CB714006) supported by the National Basic Research Program of China
文摘The discrete element method (DEM) was used to simulate the flow characteristic and strength characteristic of the conditioned sands in the earth pressure balance (EPB) tunneling. In the laboratory the conditioned sands were reproduced and the slump test and the direct shear test of the conditioned sands were implemented. A DEM equivalent model that can simulate the macro mechanical characteristic of the conditioned sands was proposed,and the corresponding numerical models of the slump test and the shear test were established. By selecting proper DEM model parameters,the errors of the slump values between the simulation results and the test results are in the range of 10.3%-14.3%,and the error of the curves between the shear displacement and the shear stress calculated with the DEM simulation is 4.68%-16.5% compared with that of the laboratory direct shear test. This illustrates that the proposed DEM equivalent model can approximately simulate the mechanical characteristics of the conditioned sands,which provides the basis for further simulation of the interaction between the conditioned soil and the chamber pressure system of the EPB machine.
基金Project(2007CB714006) supported by the National Basic Research Program of China
文摘In order to exactly provide scientific basis for pressure dynamic balance control of working chamber of earth pressure balance shield (EPBS),study on optimal arrangement of pressure measurement points in working chamber was conducted. Based on mathematical description of optimal arrangement for pressure measurement points,fuzzy clustering analysis and discriminant analysis were used to divide pressure regions of nodes on bulkhead. Finally,the selection method of optimal measurement points was proposed,and by selecting d6.28 m EPBS as study object,the case study was conducted. By contrast,based on optimal arrangement scheme of pressure measurement points,through adopting weighted algorithm,the absolute error mean of equivalent pressure of working chamber is the smallest. In addition,pressure curve of optimal arrangement points presents parabola,and it can show the state of pressure distribution on bulkhead truly. It is concluded that the optimal arrangement method of pressure measurement points in working chamber is effective and feasible,and the method can provide basis for realizing high precision pressure control of EPBS.
