Heat shock protein 90 (Hsp90) is a major heatshock protein whose functions are necessary for livingorganisms, including both procaryotes and eucaryotes.Human Hsp90 consists of two forms, Hsp90α andHsp90β. Expression...Heat shock protein 90 (Hsp90) is a major heatshock protein whose functions are necessary for livingorganisms, including both procaryotes and eucaryotes.Human Hsp90 consists of two forms, Hsp90α andHsp90β. Expression of Hsp90α appears to be inducible bydifferent stimuli. Adenovirus EIA gene products andtransformation with the H-ras oncogene can induce aselective overexpression of Hsp90α. Hsp90α was展开更多
The reform of the housing system in Shanghai has unexpectedly given rise to a self-governed property owners’ collective supervisory system, primarily in the form of Property Owners’ Supervisory Council (POSC), which...The reform of the housing system in Shanghai has unexpectedly given rise to a self-governed property owners’ collective supervisory system, primarily in the form of Property Owners’ Supervisory Council (POSC), which has picked up some of the government’s administrative functions. Although this new, institutionalized management model has theoretically made democratic managerial participation at the grassroots level possible, it has brought about endless problems, overt and covert, shortly after its appearance, some of which are even alarming. A comprehensive analysis of the data collected over a long period of time has led to the conclusion that this system is a failure, attributable to the overt factor related to skills in reality and the covert “priori” factor that is masked by the former. The existence of such “priori” factor once again demonstrates the deep-rooted, traditional managerial logic: Positive operations is society need only to depend upon individuals’ unstable self-disciplined morality rather than to build a system. The current paper points out that any change in the socioeconomic structure that has long been subject to the power of politics is to inevitably incur a corresponding global structural accommodation, including politics itself. To respond to the two factors for the failure, system building in the two overlapping areas is a must.展开更多
A novel conditional cell transmission model （CCTM） is a potential simulation tool because it accommodates all traffic conditions from light condition to oversaturated condition. To test the performance of the CCTM, ...A novel conditional cell transmission model （CCTM） is a potential simulation tool because it accommodates all traffic conditions from light condition to oversaturated condition. To test the performance of the CCTM, a series of experiments for sensitivity analysis were designed and performed for a multilane, two-way, three-signal sample network. Experiment 1 shows that the model is performed in a logical and expected manner with variations in traffic demand with time and direction. Experiment 2 shows when the possibility of the occurrence of a useful gap increases to 60% and 100%, the delays in left rams decrease by 5% and 15%, respectively. In Experiment 3, comparing the possibility of a conditional cell of 0 with 100%, delay of left turn and delay of the entire network were underestimated by 58% and 11%, respectively. Hence, sensitivity analysis demonstrates that by reflecting local drivers＇ behaviors properly, the CCTM provides an accurate representation of traffic flow in simulating oversaturated traffic conditions.展开更多
Double-skin facades(DSF)are a technique developed for colder climates,so few people think about whether or not it can also be used for hot-summer and cold-winter zones in China.After analyzing the problems of using DS...Double-skin facades(DSF)are a technique developed for colder climates,so few people think about whether or not it can also be used for hot-summer and cold-winter zones in China.After analyzing the problems of using DSF for hot-summer zones,this paper explored on the possibility of applying DSF in hot-summer and cold-winter zones in China.The main existing research methods for DSF were also collected and commented.If properly managed,the ventilated DSF with controlled shading devices can be used even in hot summer in China.展开更多
We report a very rare case of mitral valve dissection and aorticleft ventricular tunnel caused by possible autoimmune vasculitis.We suspected Behcet’s disease in this patient.There was no obvious clinical evidence of...We report a very rare case of mitral valve dissection and aorticleft ventricular tunnel caused by possible autoimmune vasculitis.We suspected Behcet’s disease in this patient.There was no obvious clinical evidence of infective endocarditis.Echocardiography is the diagnostic tool of choice to recognize valvular dysfunction,related pathology and possible complications.The patient may require immunosuppressive therapy due to the high likelihood of recurrence perioperation period.展开更多
Previous reports indicated that the difference ofMHC-Ⅰ and Ⅱ between donor and recipient was criticalfor the occurrence of allogenic rejection or graft versushost reaction (GVHR). This study aimed at looking forthe ...Previous reports indicated that the difference ofMHC-Ⅰ and Ⅱ between donor and recipient was criticalfor the occurrence of allogenic rejection or graft versushost reaction (GVHR). This study aimed at looking forthe possibility of reducing the risk of immunologicalrejection through transplantation tolerance induced bytransduction of MHC gene. In the present study, wetransferred donor mice MHC class I gene (H-2k^b gene)展开更多
Four Patients with tuberculous mediastinal lymphadenitis resembling leiomyoma of the oesophagus are presented. The differential diagnosis between this disease and leiomyoma of the oesophagus is discussed. In any adult...Four Patients with tuberculous mediastinal lymphadenitis resembling leiomyoma of the oesophagus are presented. The differential diagnosis between this disease and leiomyoma of the oesophagus is discussed. In any adult patient, especially young females with dysphagia and filling defects along the middle third of the oesophagus, the possibility of tuberculous mediastinal lymphadenitis should be considered in the differential diagnosis. The material here presented is based upon conventional radiologic methods which are also available in the developing countries.展开更多
The clinical and pathological records of eighty-one cases of pheochrcn ocytoma admitted to our hospital between 1960 and 1986, were reexamined. Six cases died of acute cardiac or cerebral vascular complications were a...The clinical and pathological records of eighty-one cases of pheochrcn ocytoma admitted to our hospital between 1960 and 1986, were reexamined. Six cases died of acute cardiac or cerebral vascular complications were analized and to be reported in this paper.展开更多
Antisense oligonucleotides have been shown to beunique drugs that achieve their effect by targetingmRNA with which they can hybridize and specificallyblock gene expression, offering the possibility ofspecific, rationa...Antisense oligonucleotides have been shown to beunique drugs that achieve their effect by targetingmRNA with which they can hybridize and specificallyblock gene expression, offering the possibility ofspecific, rational drug design. However, there havebeen many concerns that have limited enthusiasm forthe development of these drugs from the preclinical展开更多
Mutations are possibly the only source ofcreating heritable variability in all biologicalsystem and,many useful mutants in plants havebeen released for commercial cultivation acrossthe world.To-date throughout the wor...Mutations are possibly the only source ofcreating heritable variability in all biologicalsystem and,many useful mutants in plants havebeen released for commercial cultivation acrossthe world.To-date throughout the world about2252 mutants have been officially registered inthe FAO/IAEA mutant varieties data展开更多
Endothelial dysfunction,caused by declining impact of endothelium-derived relaxing factors and/or exaggerated production and activity of endothelium-derived contracting factors in the vascular wall,is the common conse...Endothelial dysfunction,caused by declining impact of endothelium-derived relaxing factors and/or exaggerated production and activity of endothelium-derived contracting factors in the vascular wall,is the common consequence of diabetes and hypertension.The degree of endothelial dysfunction predicts future cardiovascular outcomes.We have examined the cellular mechanisms involved in展开更多
Objective To investigate the survival of different subgroups of pulmonary hypertension due to left heart disease(PH-LHD)in heart failure patients with reduced ejection fraction(HFrEF)and to detect possible hemodynamic...Objective To investigate the survival of different subgroups of pulmonary hypertension due to left heart disease(PH-LHD)in heart failure patients with reduced ejection fraction(HFrEF)and to detect possible hemodynamic variables associated with the prognosis of these patients.展开更多
We had investigated about the situation about garden-making of Changzhou City twice where soil was serious saline and alkaline. We had also investigated the natural environment of the city. Based on these cases, we di...We had investigated about the situation about garden-making of Changzhou City twice where soil was serious saline and alkaline. We had also investigated the natural environment of the city. Based on these cases, we discussed the possible measurements about landscaping project under these conditions, so that we can give out the possible project measurements for the same area.展开更多
Let P=(po, p1,..., pn-1 ) and Q=(qo,q1..., qm-1) be two arbitrary convex polygonsin plane. In this paper, the author studies the problems of how to quickly determine their possiblecollision range and movable range. In...Let P=(po, p1,..., pn-1 ) and Q=(qo,q1..., qm-1) be two arbitrary convex polygonsin plane. In this paper, the author studies the problems of how to quickly determine their possiblecollision range and movable range. In the paper, a new sufficient and necessary condition for decidingpossible collision is proposed,and the basic characters of the oblique supporting lines are investigated,and on these grounds the problem to determine the possible collision range is transformed into thatof searching the supporting points on the sets of convex polygon vertexs. Using the strategy ofsearching simultaneously the sets of vertexes of P and Q, the author constructs the fast algorithmfor finding the supporting points, the time-complexity of which is O(log2(m + n)). Based on theseresults, the algorithms to quickly determine the range are given, which possess the time-complexityof O(log2(m+n)).展开更多
We live in the Age of Extinctions-the call for naming our time＂Anthropocene＂is no more than hubris and escapism from this colossal sin.Although the6thmass extinction has possibly already started（Barnosky et al.,201...We live in the Age of Extinctions-the call for naming our time＂Anthropocene＂is no more than hubris and escapism from this colossal sin.Although the6thmass extinction has possibly already started（Barnosky et al.,2011）,and it may prove the largest so far to be endured by life on Earth,efforts are needed not to turn this into the Age of Loneliness,when humans may find themselves Masters of the Earthbut alone（Wilson,2014）.展开更多
文摘Heat shock protein 90 (Hsp90) is a major heatshock protein whose functions are necessary for livingorganisms, including both procaryotes and eucaryotes.Human Hsp90 consists of two forms, Hsp90α andHsp90β. Expression of Hsp90α appears to be inducible bydifferent stimuli. Adenovirus EIA gene products andtransformation with the H-ras oncogene can induce aselective overexpression of Hsp90α. Hsp90α was
文摘The reform of the housing system in Shanghai has unexpectedly given rise to a self-governed property owners’ collective supervisory system, primarily in the form of Property Owners’ Supervisory Council (POSC), which has picked up some of the government’s administrative functions. Although this new, institutionalized management model has theoretically made democratic managerial participation at the grassroots level possible, it has brought about endless problems, overt and covert, shortly after its appearance, some of which are even alarming. A comprehensive analysis of the data collected over a long period of time has led to the conclusion that this system is a failure, attributable to the overt factor related to skills in reality and the covert “priori” factor that is masked by the former. The existence of such “priori” factor once again demonstrates the deep-rooted, traditional managerial logic: Positive operations is society need only to depend upon individuals’ unstable self-disciplined morality rather than to build a system. The current paper points out that any change in the socioeconomic structure that has long been subject to the power of politics is to inevitably incur a corresponding global structural accommodation, including politics itself. To respond to the two factors for the failure, system building in the two overlapping areas is a must.
基金Project(51108343)supported by the National Natural Science Foundation of ChinaProject(06121)supported by University of Transportation Center for Alabama,USA
文摘A novel conditional cell transmission model （CCTM） is a potential simulation tool because it accommodates all traffic conditions from light condition to oversaturated condition. To test the performance of the CCTM, a series of experiments for sensitivity analysis were designed and performed for a multilane, two-way, three-signal sample network. Experiment 1 shows that the model is performed in a logical and expected manner with variations in traffic demand with time and direction. Experiment 2 shows when the possibility of the occurrence of a useful gap increases to 60% and 100%, the delays in left rams decrease by 5% and 15%, respectively. In Experiment 3, comparing the possibility of a conditional cell of 0 with 100%, delay of left turn and delay of the entire network were underestimated by 58% and 11%, respectively. Hence, sensitivity analysis demonstrates that by reflecting local drivers＇ behaviors properly, the CCTM provides an accurate representation of traffic flow in simulating oversaturated traffic conditions.
文摘Double-skin facades(DSF)are a technique developed for colder climates,so few people think about whether or not it can also be used for hot-summer and cold-winter zones in China.After analyzing the problems of using DSF for hot-summer zones,this paper explored on the possibility of applying DSF in hot-summer and cold-winter zones in China.The main existing research methods for DSF were also collected and commented.If properly managed,the ventilated DSF with controlled shading devices can be used even in hot summer in China.
文摘We report a very rare case of mitral valve dissection and aorticleft ventricular tunnel caused by possible autoimmune vasculitis.We suspected Behcet’s disease in this patient.There was no obvious clinical evidence of infective endocarditis.Echocardiography is the diagnostic tool of choice to recognize valvular dysfunction,related pathology and possible complications.The patient may require immunosuppressive therapy due to the high likelihood of recurrence perioperation period.
文摘Previous reports indicated that the difference ofMHC-Ⅰ and Ⅱ between donor and recipient was criticalfor the occurrence of allogenic rejection or graft versushost reaction (GVHR). This study aimed at looking forthe possibility of reducing the risk of immunologicalrejection through transplantation tolerance induced bytransduction of MHC gene. In the present study, wetransferred donor mice MHC class I gene (H-2k^b gene)
文摘Four Patients with tuberculous mediastinal lymphadenitis resembling leiomyoma of the oesophagus are presented. The differential diagnosis between this disease and leiomyoma of the oesophagus is discussed. In any adult patient, especially young females with dysphagia and filling defects along the middle third of the oesophagus, the possibility of tuberculous mediastinal lymphadenitis should be considered in the differential diagnosis. The material here presented is based upon conventional radiologic methods which are also available in the developing countries.
文摘The clinical and pathological records of eighty-one cases of pheochrcn ocytoma admitted to our hospital between 1960 and 1986, were reexamined. Six cases died of acute cardiac or cerebral vascular complications were analized and to be reported in this paper.
文摘Antisense oligonucleotides have been shown to beunique drugs that achieve their effect by targetingmRNA with which they can hybridize and specificallyblock gene expression, offering the possibility ofspecific, rational drug design. However, there havebeen many concerns that have limited enthusiasm forthe development of these drugs from the preclinical
文摘Mutations are possibly the only source ofcreating heritable variability in all biologicalsystem and,many useful mutants in plants havebeen released for commercial cultivation acrossthe world.To-date throughout the world about2252 mutants have been officially registered inthe FAO/IAEA mutant varieties data
文摘Endothelial dysfunction,caused by declining impact of endothelium-derived relaxing factors and/or exaggerated production and activity of endothelium-derived contracting factors in the vascular wall,is the common consequence of diabetes and hypertension.The degree of endothelial dysfunction predicts future cardiovascular outcomes.We have examined the cellular mechanisms involved in
文摘Objective To investigate the survival of different subgroups of pulmonary hypertension due to left heart disease(PH-LHD)in heart failure patients with reduced ejection fraction(HFrEF)and to detect possible hemodynamic variables associated with the prognosis of these patients.
文摘We had investigated about the situation about garden-making of Changzhou City twice where soil was serious saline and alkaline. We had also investigated the natural environment of the city. Based on these cases, we discussed the possible measurements about landscaping project under these conditions, so that we can give out the possible project measurements for the same area.
文摘Let P=(po, p1,..., pn-1 ) and Q=(qo,q1..., qm-1) be two arbitrary convex polygonsin plane. In this paper, the author studies the problems of how to quickly determine their possiblecollision range and movable range. In the paper, a new sufficient and necessary condition for decidingpossible collision is proposed,and the basic characters of the oblique supporting lines are investigated,and on these grounds the problem to determine the possible collision range is transformed into thatof searching the supporting points on the sets of convex polygon vertexs. Using the strategy ofsearching simultaneously the sets of vertexes of P and Q, the author constructs the fast algorithmfor finding the supporting points, the time-complexity of which is O(log2(m + n)). Based on theseresults, the algorithms to quickly determine the range are given, which possess the time-complexityof O(log2(m+n)).
文摘We live in the Age of Extinctions-the call for naming our time＂Anthropocene＂is no more than hubris and escapism from this colossal sin.Although the6thmass extinction has possibly already started（Barnosky et al.,2011）,and it may prove the largest so far to be endured by life on Earth,efforts are needed not to turn this into the Age of Loneliness,when humans may find themselves Masters of the Earthbut alone（Wilson,2014）.
