Objective:Vascular dilation dysfunction has been linked with risk of cardiovascular disease.This study was undertaken to investigate the relationship between physical activity and vascular dilation function in healthy...Objective:Vascular dilation dysfunction has been linked with risk of cardiovascular disease.This study was undertaken to investigate the relationship between physical activity and vascular dilation function in healthy middle-aged adults to help explaining the effect of physical activity on preventing cardiovascular disease.Method:We recruited 91 healthy middle-aged adults to complete a self-report 7-day physical activity recall questionnaire and an exam of brachial artery flow-mediated dilation(FMD) and Nitroglycerin-mediated dilation(NMD) detected by ultrasound.The relationship between physical activity level(PAL) and FMD and NMD were explored.Result:Physical activity showed a significant and positive relationship with the brachial artery FMD,even after adjustment for possible confounding factors(r=0.363,P<0.01).The group of high physical activity level had the highest FMD.The means of FMD(%) in low,moderate and high PAL groups were respectively 8.70%±3.93%,9.01%±3.22% and 12.38±5.67% with significant difference between individuals of low and high PAL and between moderate and high PAL group(P<0.01).The means of NMD(%) is 25.13%±6.52%,24.38%±5.44% and 29.50%±7.25% respectively(P> 0.05) and there was no significant difference among three groups.There was no positive relation between PAL and FMD in premenopausal females but in men and postmenopausal females.Although individuals of high PAL have the best FMD,the moderate PAL can also retard FMD decrease with ageing.Conclusion:Maintaining high physical activity level can enhance endothelial-dependent vascular dilation,and moderate or high physical activity level can prevent endothelial-dependent vascular dilation declining with aging,which may contribute to decrease risk of cardiovascular disease in healthy middle-aged adults.展开更多
Porous carbons are extensively applied in gas separation, water purification, catalytic reaction, and electrochemical processing, attributing to their high specific surface area, large pore volume, chemical inertness,...Porous carbons are extensively applied in gas separation, water purification, catalytic reaction, and electrochemical processing, attributing to their high specific surface area, large pore volume, chemical inertness, and good mechanical and thermal stability. The templating method is widely used to synthesize porous carbons with the controlled pore structure. Among them, preparation of diatomite-templated carbons attracts increasing attention because the obtained carbon has unique developed macropores and exhibits the promising application in adsorption and support of large-sized molecules. Macroporous diatomite-templated carbons are prepared by using additive or inherent solid acid sites of diatomite as the catalyst. The obtained carbons showed tubular and pillared macroporous structures, and had a few mesopores and micropores. However, the carbons possessed the small specific surface area and micropore volume, and thus showed the low adsorption capacity of small-sized molecules, such as methylene blue (MB). In this case, enhancement of porosity, especially microporosity, is necessary.展开更多
目的本研究旨在分析身体活动和肌少症的研究热点与演化。方法基于Web of Science核心合集数据库,检索了1995—2022年身体活动和肌少症相关的文献,借助Citespace软件对检索数据进行发文量、合作分析、学科领域、关键词及共被引等可视化...目的本研究旨在分析身体活动和肌少症的研究热点与演化。方法基于Web of Science核心合集数据库,检索了1995—2022年身体活动和肌少症相关的文献,借助Citespace软件对检索数据进行发文量、合作分析、学科领域、关键词及共被引等可视化分析。结果共1834篇文献纳入研究。中国总发文量位于第3位,发文量为173篇,BCD为0.06。发文最多的国家和机构是美国(431/0.54)与美国国立衰老研究所(36/0.12)。老年学和老年病学、公共卫生、康复与其他学科联系较为紧密。当前抗阻运动、有氧运动等身体活动是肌少症干预的热点研究领域,联合多运动形式与生活方式改变成为老龄化背景下防治肌少症的重要应用领域。结论本文研究结果定量显示了身体活动与肌少症研究的发展、热点分布和应用情况,为相关研究人员把握领域发展趋势及挖掘新的研究生长点提供了参考。展开更多
文摘Objective:Vascular dilation dysfunction has been linked with risk of cardiovascular disease.This study was undertaken to investigate the relationship between physical activity and vascular dilation function in healthy middle-aged adults to help explaining the effect of physical activity on preventing cardiovascular disease.Method:We recruited 91 healthy middle-aged adults to complete a self-report 7-day physical activity recall questionnaire and an exam of brachial artery flow-mediated dilation(FMD) and Nitroglycerin-mediated dilation(NMD) detected by ultrasound.The relationship between physical activity level(PAL) and FMD and NMD were explored.Result:Physical activity showed a significant and positive relationship with the brachial artery FMD,even after adjustment for possible confounding factors(r=0.363,P<0.01).The group of high physical activity level had the highest FMD.The means of FMD(%) in low,moderate and high PAL groups were respectively 8.70%±3.93%,9.01%±3.22% and 12.38±5.67% with significant difference between individuals of low and high PAL and between moderate and high PAL group(P<0.01).The means of NMD(%) is 25.13%±6.52%,24.38%±5.44% and 29.50%±7.25% respectively(P> 0.05) and there was no significant difference among three groups.There was no positive relation between PAL and FMD in premenopausal females but in men and postmenopausal females.Although individuals of high PAL have the best FMD,the moderate PAL can also retard FMD decrease with ageing.Conclusion:Maintaining high physical activity level can enhance endothelial-dependent vascular dilation,and moderate or high physical activity level can prevent endothelial-dependent vascular dilation declining with aging,which may contribute to decrease risk of cardiovascular disease in healthy middle-aged adults.
文摘Porous carbons are extensively applied in gas separation, water purification, catalytic reaction, and electrochemical processing, attributing to their high specific surface area, large pore volume, chemical inertness, and good mechanical and thermal stability. The templating method is widely used to synthesize porous carbons with the controlled pore structure. Among them, preparation of diatomite-templated carbons attracts increasing attention because the obtained carbon has unique developed macropores and exhibits the promising application in adsorption and support of large-sized molecules. Macroporous diatomite-templated carbons are prepared by using additive or inherent solid acid sites of diatomite as the catalyst. The obtained carbons showed tubular and pillared macroporous structures, and had a few mesopores and micropores. However, the carbons possessed the small specific surface area and micropore volume, and thus showed the low adsorption capacity of small-sized molecules, such as methylene blue (MB). In this case, enhancement of porosity, especially microporosity, is necessary.
文摘目的本研究旨在分析身体活动和肌少症的研究热点与演化。方法基于Web of Science核心合集数据库,检索了1995—2022年身体活动和肌少症相关的文献,借助Citespace软件对检索数据进行发文量、合作分析、学科领域、关键词及共被引等可视化分析。结果共1834篇文献纳入研究。中国总发文量位于第3位,发文量为173篇,BCD为0.06。发文最多的国家和机构是美国(431/0.54)与美国国立衰老研究所(36/0.12)。老年学和老年病学、公共卫生、康复与其他学科联系较为紧密。当前抗阻运动、有氧运动等身体活动是肌少症干预的热点研究领域,联合多运动形式与生活方式改变成为老龄化背景下防治肌少症的重要应用领域。结论本文研究结果定量显示了身体活动与肌少症研究的发展、热点分布和应用情况,为相关研究人员把握领域发展趋势及挖掘新的研究生长点提供了参考。