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Joint Optimization of Routing and Resource Allocation in Decentralized UAV Networks Based on DDQN and GNN
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作者 Nawaf Q.H.Othman YANG Qinghai JIANG Xinpei 《电讯技术》 北大核心 2026年第1期1-10,共10页
Optimizing routing and resource allocation in decentralized unmanned aerial vehicle(UAV)networks remains challenging due to interference and rapidly changing topologies.The authors introduce a novel framework combinin... Optimizing routing and resource allocation in decentralized unmanned aerial vehicle(UAV)networks remains challenging due to interference and rapidly changing topologies.The authors introduce a novel framework combining double deep Q-networks(DDQNs)and graph neural networks(GNNs)for joint routing and resource allocation.The framework uses GNNs to model the network topology and DDQNs to adaptively control routing and resource allocation,addressing interference and improving network performance.Simulation results show that the proposed approach outperforms traditional methods such as Closest-to-Destination(c2Dst),Max-SINR(mSINR),and Multi-Layer Perceptron(MLP)-based models,achieving approximately 23.5% improvement in throughput,50% increase in connection probability,and 17.6% reduction in number of hops,demonstrating its effectiveness in dynamic UAV networks. 展开更多
关键词 decentralized UAV network resource allocation routing algorithm GNN DDQN DRL
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Exploring the material basis and mechanisms of the action of Hibiscus mutabilis L. for its anti-inflammatory effects based on network pharmacology and cell experiments
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作者 Wenyuan Chen Xiaolan Chen +2 位作者 Jing Wan Qin Deng Yong Gao 《日用化学工业(中英文)》 北大核心 2026年第1期55-64,共10页
To explore the material basis and mechanisms of the anti-inflammatory effects of Hibiscus mutabilis L..The active ingredients and potential targets of Hibiscus mutabilis L.were obtained through the literature review a... To explore the material basis and mechanisms of the anti-inflammatory effects of Hibiscus mutabilis L..The active ingredients and potential targets of Hibiscus mutabilis L.were obtained through the literature review and SwissADME platform.Genes related to the inflammation were collected using Genecards and OMIM databases,and the intersection genes were submitted on STRING and DAVID websites.Then,the protein interaction network(PPI),gene ontology(GO)and pathway(KEGG)were analyzed.Cytoscape 3.7.2 software was used to construct the“Hibiscus mutabilis L.-active ingredient-target-inflammation”network diagram,and AutoDockTools-1.5.6 software was used for the molecular docking verification.The antiinflammatory effect of Hibiscus mutabilis L.active ingredient was verified by the RAW264.7 inflammatory cell model.The results showed that 11 active components and 94 potential targets,1029 inflammatory targets and 24 intersection targets were obtained from Hibiscus mutabilis L..The key anti-inflammatory active ingredients of Hibiscus mutabilis L.are quercetin,apigenin and luteolin.Its action pathway is mainly related to NF-κB,cancer pathway and TNF signaling pathway.Cell experiments showed that total flavonoids of Hibiscus mutabilis L.could effectively inhibit the expression of tumor necrosis factor(TNF-α),interleukin 8(IL-8)and epidermal growth factor receptor(EGFR)in LPS-induced RAW 264.7 inflammatory cells.It also downregulates the phosphorylation of human nuclear factor ĸB inhibitory protein α(IĸBα)and NF-κB p65 subunit protein(p65).Overall,the anti-inflammatory effect of Hibiscus mutabilis L.is related to many active components,many signal pathways and targets,which provides a theoretical basis for its further development and application. 展开更多
关键词 Hibiscus mutabilis L. INFLAMMATION network pharmacology molecular docking cell validation
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Multi-responsive Hydrogel Featuring Synergistic Regulation of AIE and Mechanical Behaviors via Dynamic Hydrogen Bonding Network
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作者 ZHANG Yangdaiyi SHAO Yan JIANG Shimei 《高等学校化学学报》 北大核心 2026年第4期141-152,共12页
A multi-stimuli-responsive hydrogel,P(VI-co-MAAC-NE),was successfully constructed by covalently integrating the aggregation-induced emission(AIE)moiety(Z)-N-(4-(1-cyano-2-(4-(diethylamino)phenyl)vinyl)-phenyl)methacry... A multi-stimuli-responsive hydrogel,P(VI-co-MAAC-NE),was successfully constructed by covalently integrating the aggregation-induced emission(AIE)moiety(Z)-N-(4-(1-cyano-2-(4-(diethylamino)phenyl)vinyl)-phenyl)methacrylamide(NE)into a dynamic hydrogen-bonding network composed of 1-vinylimidazole(VI)and methacrylic acid(MAAC)groups.The dense hydrogen-bonding network not only provides enhanced mechanical robustness,but also significantly enhances the AIE effect of NE by restricting its molecular motion.Under various external stimuli,the hydrogen bonds within the hydrogel network undergo reversible dissociation and reformation,thus enabling synergistic modulation of the hydrogel’s mechanical properties and luminescence behavior.Specifically,organic solvents disrupt the hydrogen-bonding network and the aggregation of the AIE moiety NE,resulting in macroscopic swelling and fluorescence quenching of the hydrogel.In strongly acidic conditions,protonation of NE molecules suppresses the intramolecular charge transfer(ICT)process,yielding a blue-shifted emission band accompanied by intense blue fluorescence;in highly alkaline environments,deprotonation of carboxyl groups induces hydrogel swelling and disperses NE aggregates,leading to pronounced fluorescence quenching.Moreover,the system exhibits thermally activated shape-memory behavior:heating above the glass transition temperature(T_(g):ca.62℃)softens the hydrogel to allow programmable reshaping,and subsequent hydrogen bond reformation at ambient conditions locks in the resultant geometries without sacrificing the hydrogel’s fluorescence performance.By capitalizing on these multi-stimuli-responsive characteristics and shape-memory behavior,the potential of hydrogel P(VI-co-MAAC-NE)for advanced information encryption and anti-counterfeiting applications is demonstrated.This work not only provides a versatile material platform for sensing and information storage,but also offers new insights into the design of intelligent soft materials integrating AIE features with dynamically regulated supramolecular network structures. 展开更多
关键词 Aggregation-induced emission(AIE) Multi-responsive hydrogel Mechanical properties Hydrogen bonds network
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Underwater Image Enhancement Based on Depthwise Separable Convolution-Based Generative Adversarial Network
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作者 ZENG Jun-yang SI Zhan-jun 《印刷与数字媒体技术研究》 北大核心 2026年第1期60-66,共7页
The existence of absorption and reflection of light underwater leads to problems such as color distortion and blue-green bias in underwater images.In this study,a depthwise separable convolution-based generative adver... The existence of absorption and reflection of light underwater leads to problems such as color distortion and blue-green bias in underwater images.In this study,a depthwise separable convolution-based generative adversarial network(GAN)algorithm was proposed.Taking GAN as the basic framework,it combined a depthwise separable convolution module,attention mechanism,and reconstructed convolution module to realize the enhancement of underwater degraded images.Multi-scale features were captured by the depthwise separable convolution module,and the attention mechanism was utilized to enhance attention to important features.The reconstructed convolution module further extracts and fuses local and global features.Experimental results showed that the algorithm performs well in improving the color bias and blurring of underwater images,with PSNR reaching 27.835,SSIM reaching 0.883,UIQM reaching 3.205,and UCIQE reaching 0.713.The enhanced image outperforms the comparison algorithm in both subjective and objective metrics. 展开更多
关键词 Underwater image enhancement Generating adversarial network Depthwise separable convolution
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Analysis of DC Aging Characteristics of Stable ZnO Varistors Based on Voronoi Network and Finite Element Simulation Model
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作者 ZHANG Ping LU Mingtai +1 位作者 LU Tiantian YUE Yinghu 《材料导报》 北大核心 2026年第2期20-28,共9页
In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results i... In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results in increased leakage current,decreased breakdown voltage,and lower nonlinearity,ultimately compromising their protective performance.To investigate the evolution in electrical properties during DC aging,this work developed a finite element model based on Voronoi networks and conducted accelerated aging tests on commercial varistors.Throughout the aging process,current-voltage characteristics and Schottky barrier parameters were measured and analyzed.The results indicate that when subjected to constant voltage,current flows through regions with larger grain sizes,forming discharge channels.As aging progresses,the current focus increases on these channels,leading to a decline in the varistor’s overall performance.Furthermore,analysis of the Schottky barrier parameters shows that the changes in electrical performance during aging are non-monotonic.These findings offer theoretical support for understanding the aging mechanisms and condition assessment of modern stable ZnO varistors. 展开更多
关键词 ZnO varistors Voronoi network DC aging finite element method(FEM) current distribution double Schottky barrier theory
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Bioinformatics and Network Pharmacology Confirmed that Red Mulberry Water Extract Can Improve Diabetes
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作者 LIU Jiaqi ZANG Yanqing 《食品工业科技》 北大核心 2026年第8期456-469,共14页
Type 2 diabetes mellitus(T2DM)was identified as the most prevalent form of diabetes.This study employed an integrated strategy combining network pharmacology,metabolomics,and experimental validation to elucidate the t... Type 2 diabetes mellitus(T2DM)was identified as the most prevalent form of diabetes.This study employed an integrated strategy combining network pharmacology,metabolomics,and experimental validation to elucidate the therapeutic mechanisms of red mulberry water extract(RMW)in T2DM.Systematic analysis identified six bioactive constituents,with four key components(cyanidin,quercetin,morin,andβ-carotene)demonstrating significant interactions with diabetes-related targets.Network pharmacology revealed these compounds modulate critical pathways including AMPK(P=2.3×10^(−5)),PI3K-Akt(P=1.8×10^(−4)),and PPAR signaling(P=3.1×10^(−3)).In diabetic mice,treatment significantly improved glycemic control(32.5%reduction in fasting glucose,P<0.01),lipid profiles(36.7%lower TG,P<0.05),antioxidant activity(2.1-fold increased SOD,P<0.05),and inflammation(42%reduced TNF-α,P<0.05).Metabolomic analysis further confirmed alterations in catecholamine and lipid metabolism pathways.These findings collectively demonstrate mulberry's multi-target therapeutic potential through synergistic regulation of glucose metabolism,lipid homeostasis,oxidative stress,and inflammatory responses in diabetes. 展开更多
关键词 MULBERRY type 2 diabetes mellitus(T2DM) network pharmacology bioactive compounds insulin resistance PPAR signaling oxidative stress
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ReacNetwork: A method for large-scale reaction network analysis of energetic materials
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作者 Zhonghui Chen Chengjie Tong +5 位作者 Qiang Gan Jie Li Yuhang Tao Gen Li Yajun Wang Changgen Feng 《Defence Technology(防务技术)》 2026年第3期202-216,共15页
The combustion and detonation processes of energetic materials exhibit remarkable complexity and ultra-fast transient characteristics.While reactive molecular dynamics has been extensively employed to investigate the ... The combustion and detonation processes of energetic materials exhibit remarkable complexity and ultra-fast transient characteristics.While reactive molecular dynamics has been extensively employed to investigate the reaction dynamics of energetic materials,its utility is often constrained to capturing only fundamental reaction events and species information,thereby limiting mechanistic investigations of complex reaction pathways.To elucidate the topological features of energetic material reaction networks and identify critical reaction pathways with high fidelity,this study presents ReacNetwork-an advanced large-scale reaction network analysis methodology that synergistically integrates complex network theory with molecular simulation techniques.Specifically,we have developed a multi-dimensional feature screening protocol based on node centrality metrics and K-shell decomposition algorithms.Takingα-Hexahydro-1,3,5-trinitro-1,3,5-triazine(α-RDX)as the subject,we successfully constructed a comprehensive high-temperature thermal decomposition reaction network consisting of 1,134 distinct chemical species and 3,626 elementary reactions.Through systematic application of community detection algorithms and global topological feature extraction techniques,we achieved effective dimensionality reduction and successfully identified the dominant reaction pathway within theα-RDX thermal decomposition network.The computational results not only validate the well-established initial reaction mechanism dominated by N-NO2 homolytic bond cleavage,but also provide unprecedented visualization ofα-RDX framework ring-opening dynamics and subsequent radical chain propagation networks. 展开更多
关键词 Energetic materials RDX reaction network Multi-dimensional feature screening network dimensionality reduction and analysis
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Model construction and topology analysis of logistics equipment system-of-systems heterogeneous network
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作者 YANG Fanghua JIN Cong +2 位作者 ZHAO Zihan LU Yanjing LI Pei 《Journal of Systems Engineering and Electronics》 2026年第2期594-603,共10页
With the improvement of the informatization and intelligence level of logistics equipment,the interactive and collaborative relationships between equipment entities become complex,and the uncertainty problems emerge i... With the improvement of the informatization and intelligence level of logistics equipment,the interactive and collaborative relationships between equipment entities become complex,and the uncertainty problems emerge in the equipment system-of-systems.Herein,a heterogeneous network model is built to describe logistics equipment system-of-systems,which considers the heterogeneity and complex connections of different logistics equipment nodes.Next,the topological structure properties of this model are analyzed.On this basis,the experiments on the logistics equipment system-of-systems under attack strategies including degree attacks,betweenness centrality attacks and random attacks are taken to assess the changes of structural invulnerability.Results show that the logistics equipment system-of-systems heterogeneous network has similar topological structure characteristics of typical complex networks,namely small-world effect and scale-free characteristics,indicating that the flow,sharing,and synchronization between logistics equipment entities in the network are relatively easy.Meantime,the key logistics equipment nodes with large values such as degree,closeness centrality,and betweenness centrality should be protected in the logistics equipment system-ofsystems heterogeneous network against deliberate attacks.The current work provides a perspective for demonstration and affords the theoretical support for development and decisionmaking of logistics equipment system-of-systems. 展开更多
关键词 logistics equipment system-of-systems heterogeneous network topology analysis equipment demonstration
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Bio-inspired offset array design for enhanced range in underwater active electrosensing with neural network-based localization
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作者 Meijiang Hou Jiegang Peng +2 位作者 Minan Yang Taoyu Jiang Yang Chen 《Defence Technology(防务技术)》 2026年第3期217-245,共29页
Addressing the critical detection range limitation in active electrosensing(AES)for underwater sensing,this study proposes an enhanced AES system via novel array optimization.While AES offers advantages like interfere... Addressing the critical detection range limitation in active electrosensing(AES)for underwater sensing,this study proposes an enhanced AES system via novel array optimization.While AES offers advantages like interference immunity,acoustic stealth detection,and low cost,its short range restricts applicability.A target perturbation model under differential signal acquisition reveals that signal strength increases with local electric field intensity,target size,differential channel spacing,and conductivity contrast,but decreases with target-electrode distance.To extend detection,novel array configurations were explored.Simulations demonstrate that both rectangular and offset arrays significantly outperform the traditional collinear layout.Specifically,an offset array(with 8 m transmitting–receiving spacing)achieved an effective detection range enhancement exceeding 83%under the same distortion threshold while maintaining simplified electrode structure.Experimental validation confirmed a 100%increase in maximum detection distance to 5 m under identical noise thresholds compared to the collinear array.Furthermore,a fully connected neural network-based localization model achieved a mean positioning error of 14.12 cm at 3.15 m in static scenarios.In dynamic scenarios within 1–3 m,mean errors were controlled between 13.19 cm and 27.56 cm.Mechanistic analysis indicates that increasing the array baseline enhances the signal-to-noise ratio by simultaneously suppressing near-field environmental noise and amplifying far-field signal reception.Structural innovations in array design enabled this study to significantly expand the detection range of AES systems without compromising cost efficiency.These advancements directly promote the engineering application of AES technology,offering critical technical support for underwater defense security monitoring,long-range early warning systems,and maritime rights protection. 展开更多
关键词 Active electrical sensing Target perturbation model Array optimization Detection range Fuly connected neural network
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Real-time decision support for bolter recovery safety:Long short-term memory network-driven aircraft sequencing
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作者 Wei Han Changjiu Li +4 位作者 Xichao Su Yong Zhang Fang Guo Tongtong Yu Xuan Li 《Defence Technology(防务技术)》 2026年第2期184-205,共22页
The highly dynamic nature,strong uncertainty,and coupled multiple safety constraints inherent in carrier aircraft recovery operations pose severe challenges for real-time decision-making.Addressing bolter scenarios,th... The highly dynamic nature,strong uncertainty,and coupled multiple safety constraints inherent in carrier aircraft recovery operations pose severe challenges for real-time decision-making.Addressing bolter scenarios,this study proposes an intelligent decision-making framework based on a deep long short-term memory Q-network.This framework transforms the real-time sequencing for bolter recovery problem into a partially observable Markov decision process.It employs a stacked long shortterm memory network to accurately capture the long-range temporal dependencies of bolter event chains and fuel consumption.Furthermore,it integrates a prioritized experience replay training mechanism to construct a safe and adaptive scheduling system capable of millisecond-level real-time decision-making.Experimental demonstrates that,within large-scale mass recovery scenarios,the framework achieves zero safety violations in static environments and maintains a fuel safety violation rate below 10%in dynamic scenarios,with single-step decision times at the millisecond level.The model exhibits strong generalization capability,effectively responding to unforeseen emergent situations—such as multiple bolters and fuel emergencies—without requiring retraining.This provides robust support for efficient carrier-based aircraft recovery operations. 展开更多
关键词 Carrier-based aircraft Recovery scheduling Deep reinforcement learning Long short-term memory networks Dynamic real-time decision-making
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Cascading failure modeling and survivability analysis of weak-communication underwater unmanned swarm networks
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作者 Yifan Yuan Xiaohong Shen +3 位作者 Lin Sun Ke He Yongsheng Yan Haiyan Wang 《Defence Technology(防务技术)》 2026年第2期66-82,共17页
Cascading failures pose a serious threat to the survivability of underwater unmanned swarm networks(UUSNs),significantly limiting their service ability in collaborative missions such as military reconnaissance and env... Cascading failures pose a serious threat to the survivability of underwater unmanned swarm networks(UUSNs),significantly limiting their service ability in collaborative missions such as military reconnaissance and environmental monitoring.Existing failure models primarily focus on power grids and traffic systems,and don't address the unique challenges of weak-communication UUSNs.In UUSNs,cascading failure present a complex and dynamic process driven by the coupling of unstable acoustic channels,passive node drift,adversarial attacks,and network heterogeneity.To address these challenges,a directed weighted graph model of UUSNs is first developed,in which node positions are updated according to ocean-current-driven drift and link weights reflect the probability of successful acoustic transmission.Building on this UUSNs graph model,a cascading failure model is proposed that integrates a normal-failure-recovery state-cycle mechanism,multiple attack strategies,and routingbased load redistribution.Finally,under a five-level connectivity UUSNs scheme,simulations are conducted to analyze how dynamic topology,network load,node recovery delay,and attack modes jointly affect network survivability.The main findings are:(1)moderate node drift can improve survivability by activating weak links;(2)based-energy routing(BER)outperform based-depth routing(BDR)in harsh conditions;(3)node self-recovery time is critical to network survivability;(4)traditional degree-based critical node metrics are inadequate for weak-communication UUSNs.These results provide a theoretical foundation for designing robust survivability mechanisms in weak-communication UUSNs. 展开更多
关键词 Weak communication Underwater unmanned swarm networks(UUSNs) Link success probability Cascading failure Node self-recovery Survivability analysis
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Performance improvement method of new R&D institutions considering Bayesian network
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作者 ZHU Jianjun JIANG Lin 《Journal of Systems Engineering and Electronics》 2026年第1期257-271,共15页
A performance improvement model of research and development(R&D)institutions based on evolutionary game and Bayesian network is proposed.First,the nature and performance factors of new R&D institutions are sys... A performance improvement model of research and development(R&D)institutions based on evolutionary game and Bayesian network is proposed.First,the nature and performance factors of new R&D institutions are systematically analyzed,the appropriate factor model is found,and the sharing of performance benefits between institutions and employees,the change in distribution proportion,and the risk of institutional improvement and employee cooperation are considered.Second,based on the mechanism improvement and employee cooperation,the payment matrix is given and evolutionary game analysis is carried out to obtain a stable and balanced institutional improvement probability and employee cooperation probability.These two probability values are substituted into the Bayesian network model of performance improvement of new R&D institutions,and the posterior probability of performance improvement is predicted by Bayesian network reasoning and diagnosis to find effective improvement measures.Finally,practical case analysis is given to verify the effectiveness and practicability of the proposed method. 展开更多
关键词 new research and development(R&D)institution performance improvement evolutionary game Bayesian network conditional probability
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Satellite handover strategies based on minimum routing hops for mega LEO satellite networks
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作者 ZHU Hongtao WANG Xinyu +2 位作者 WANG Zhenyong LI Dezhi GUO Qing 《Journal of Systems Engineering and Electronics》 2026年第1期64-74,共11页
Mega low Earth orbit(LEO)satellite networks serve as effective complements to terrestrial networks.However,the dual mobility of users and LEO satellites makes inter-satellite handovers more frequent for users.Moreover... Mega low Earth orbit(LEO)satellite networks serve as effective complements to terrestrial networks.However,the dual mobility of users and LEO satellites makes inter-satellite handovers more frequent for users.Moreover,there are both ascending and descending segments in widely deployed walker-delta constellations.Even if the locations of users do not change,when the access satellites of the communicating parties are not in the same ascending or descending segment,the end-to-end latency between them will increase.To address this challenge,the self-decision handover(SDH)strategy and the joint decision handover(JDH)strategy are proposed,and they both incorporate the routing hops as a crucial handover criterion to minimize the end-to-end latency.In addition,the shortest route hop-count algorithm is designed to assist in the handover decision-making process.Simulations demonstrate that the proposed handover strategies outperform the traditional handover strategies in terms of the number of handovers and end-to-end latency. 展开更多
关键词 mega low Earth orbit(LEO)satellite network walker-delta constellation self-decision handover joint decision handover minimum routing hop
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Embedded RF fingerprint interpretation:multi-channel complex residual networks with adaptive sphere space decision boundaries
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作者 DUAN Yongsheng ZHANG Junning +1 位作者 XUE Lei XU Ying 《Journal of Systems Engineering and Electronics》 2026年第1期137-147,共11页
Despite the superior advantages of specific emitter identification in extracting emitter features from in-phase and quadrature(I/Q)signals,challenges persist due to signal-type confusion and background noise interfere... Despite the superior advantages of specific emitter identification in extracting emitter features from in-phase and quadrature(I/Q)signals,challenges persist due to signal-type confusion and background noise interference.To address those limitations,this paper proposes a multi-channel contrast prediction coding and complex-valued residuals network(MCPC-MCVResNet)framework.This model employs contrast prediction techniques to directly extract discriminative features from electromagnetic signal sequences,effectively capturing both amplitude and phase information within I/Q data.A core innovation of this approach is the sphere space softmax(SS-softmax)loss,which optimizes intra-class clustering density of while establishing well-defined boundaries between distinct emitters.The SS-softmax mechanism significantly enhances the model's capacity to discern subtle variations among radiation emitters.Experimental results demonstrate superior identification accuracy,rapid convergence,and exceptional robustness in low signal-to-noise ratio environments. 展开更多
关键词 specific emitter identification(SEI) multi-channel complex-valued residual network(MCVResNet) sphere spacesoftmax(SS-softmax)
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改进Deep Q Networks的交通信号均衡调度算法
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作者 贺道坤 《机械设计与制造》 北大核心 2025年第4期135-140,共6页
为进一步缓解城市道路高峰时段十字路口的交通拥堵现象,实现路口各道路车流均衡通过,基于改进Deep Q Networks提出了一种的交通信号均衡调度算法。提取十字路口与交通信号调度最相关的特征,分别建立单向十字路口交通信号模型和线性双向... 为进一步缓解城市道路高峰时段十字路口的交通拥堵现象,实现路口各道路车流均衡通过,基于改进Deep Q Networks提出了一种的交通信号均衡调度算法。提取十字路口与交通信号调度最相关的特征,分别建立单向十字路口交通信号模型和线性双向十字路口交通信号模型,并基于此构建交通信号调度优化模型;针对Deep Q Networks算法在交通信号调度问题应用中所存在的收敛性、过估计等不足,对Deep Q Networks进行竞争网络改进、双网络改进以及梯度更新策略改进,提出相适应的均衡调度算法。通过与经典Deep Q Networks仿真比对,验证论文算法对交通信号调度问题的适用性和优越性。基于城市道路数据,分别针对两种场景进行仿真计算,仿真结果表明该算法能够有效缩减十字路口车辆排队长度,均衡各路口车流通行量,缓解高峰出行方向的道路拥堵现象,有利于十字路口交通信号调度效益的提升。 展开更多
关键词 交通信号调度 十字路口 Deep Q networks 深度强化学习 智能交通
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rTMS Improves Cognitive Function and Brain Network Connectivity in Patients With Alzheimer’s Disease 被引量:1
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作者 XU Gui-Zhi LIU Lin +4 位作者 GUO Miao-Miao WANG Tian GAO Jiao-Jiao JI Yong WANG Pan 《生物化学与生物物理进展》 北大核心 2025年第8期2131-2145,共15页
Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,n... Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,neural oscillatory dynamics,and brain network reorganization remain unclear.This investigation seeks to systematically evaluate the therapeutic potential of rTMS as a non-invasive neuromodulatory intervention through a multimodal framework integrating clinical assessments,molecular profiling,and neurophysiological monitoring.Methods In this prospective double-blind trial,12 AD patients underwent a 14-day protocol of 20 Hz rTMS,with comprehensive multimodal assessments performed pre-and postintervention.Cognitive functioning was quantified using the mini-mental state examination(MMSE)and Montreal cognitive assessment(MOCA),while daily living capacities and neuropsychiatric profiles were respectively evaluated through the activities of daily living(ADL)scale and combined neuropsychiatric inventory(NPI)-Hamilton depression rating scale(HAMD).Peripheral blood biomarkers,specifically Aβ1-40 and phosphorylated tau(p-tau181),were analyzed to investigate the effects of rTMS on molecular metabolism.Spectral power analysis was employed to investigate rTMS-induced modulations of neural rhythms in AD patients,while brain network analyses incorporating topological properties were conducted to examine stimulus-driven network reorganization.Furthermore,systematic assessment of correlations between cognitive scale scores,blood biomarkers,and network characteristics was performed to elucidate cross-modal therapeutic associations.Results Clinically,MMSE and MOCA scores improved significantly(P<0.05).Biomarker showed that Aβ1-40 level increased(P<0.05),contrasting with p-tau181 reduction.Moreover,the levels of Aβ1-40 were positively correlated with MMSE and MOCA scores.Post-intervention analyses revealed significant modulations in oscillatory power,characterized by pronounced reductions in delta(P<0.05)and theta bands(P<0.05),while concurrent enhancements were observed in alpha,beta,and gamma band activities(all P<0.05).Network analysis revealed frequency-specific reorganization:clustering coefficients were significantly decreased in delta,theta,and alpha bands(P<0.05),while global efficiency improvement was exclusively detected in the delta band(P<0.05).The alpha band demonstrated concurrent increases in average nodal degree(P<0.05)and characteristic path length reduction(P<0.05).Further research findings indicate that the changes in the clinical scale HAMD scores before and after rTMS stimulation are negatively correlated with the changes in the blood biomarkers Aβ1-40 and p-tau181.Additionally,the changes in the clinical scales MMSE and MoCA scores were negatively correlated with the changes in the node degree of the alpha frequency band and negatively correlated with the clustering coefficient of the delta frequency band.However,the changes in MMSE scores are positively correlated with the changes in global efficiency of both the delta and alpha frequency bands.Conclusion 20 Hz rTMS targeting dorsolateral prefrontal cortex(DLPFC)significantly improves cognitive function and enhances the metabolic clearance ofβ-amyloid and tau proteins in AD patients.This neurotherapeutic effect is mechanistically associated with rTMS-mediated frequency-selective neuromodulation,which enhances the connectivity of oscillatory networks through improved neuronal synchronization and optimized topological organization of functional brain networks.These findings not only support the efficacy of rTMS as an adjunctive therapy for AD but also underscore the importance of employing multiple assessment methods—including clinical scales,blood biomarkers,and EEG——in understanding and monitoring the progression of AD.This research provides a significant theoretical foundation and empirical evidence for further exploration of rTMS applications in AD treatment. 展开更多
关键词 transcranial magnetic stimulation Alzheimer’s disease power spectral density ELECTROENCEPHALOGRAM brain functional network
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Hypersonic glide vehicle trajectory prediction based on frequency enhanced channel attention and light sampling-oriented MLP network 被引量:2
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作者 Yuepeng Cai Xuebin Zhuang 《Defence Technology(防务技术)》 2025年第4期199-212,共14页
Hypersonic Glide Vehicles(HGVs)are advanced aircraft that can achieve extremely high speeds(generally over 5 Mach)and maneuverability within the Earth's atmosphere.HGV trajectory prediction is crucial for effectiv... Hypersonic Glide Vehicles(HGVs)are advanced aircraft that can achieve extremely high speeds(generally over 5 Mach)and maneuverability within the Earth's atmosphere.HGV trajectory prediction is crucial for effective defense planning and interception strategies.In recent years,HGV trajectory prediction methods based on deep learning have the great potential to significantly enhance prediction accuracy and efficiency.However,it's still challenging to strike a balance between improving prediction performance and reducing computation costs of the deep learning trajectory prediction models.To solve this problem,we propose a new deep learning framework(FECA-LSMN)for efficient HGV trajectory prediction.The model first uses a Frequency Enhanced Channel Attention(FECA)module to facilitate the fusion of different HGV trajectory features,and then subsequently employs a Light Sampling-oriented Multi-Layer Perceptron Network(LSMN)based on simple MLP-based structures to extract long/shortterm HGV trajectory features for accurate trajectory prediction.Also,we employ a new data normalization method called reversible instance normalization(RevIN)to enhance the prediction accuracy and training stability of the network.Compared to other popular trajectory prediction models based on LSTM,GRU and Transformer,our FECA-LSMN model achieves leading or comparable performance in terms of RMSE,MAE and MAPE metrics while demonstrating notably faster computation time.The ablation experiments show that the incorporation of the FECA module significantly improves the prediction performance of the network.The RevIN data normalization technique outperforms traditional min-max normalization as well. 展开更多
关键词 Hypersonic glide vehicle Trajectory prediction Frequency enhanced channel attention Light sampling-oriented MLP network
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An efficient and accurate numerical method for simulating close-range blast loads of cylindrical charges based on neural network 被引量:1
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作者 Ting Liu Changhai Chen +2 位作者 Han Li Yaowen Yu Yuansheng Cheng 《Defence Technology(防务技术)》 2025年第2期257-271,共15页
To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based sim... To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based simulation(NNS)method with higher accuracy and better efficiency was proposed.The NNS method consisted of three main steps.First,the parameters of blast loads,including the peak pressures and impulses of cylindrical charges with different aspect ratios(L/D)at different stand-off distances and incident angles were obtained by two-dimensional numerical simulations.Subsequently,incident shape factors of cylindrical charges with arbitrary aspect ratios were predicted by a neural network.Finally,reflected shape factors were derived and implemented into the subroutine of the ABAQUS code to modify the CONWEP model,including modifications of impulse and overpressure.The reliability of the proposed NNS method was verified by related experimental results.Remarkable accuracy improvement was acquired by the proposed NNS method compared with the unmodified CONWEP model.Moreover,huge efficiency superiority was obtained by the proposed NNS method compared with the CEL method.The proposed NNS method showed good accuracy when the scaled distance was greater than 0.2 m/kg^(1/3).It should be noted that there is no need to generate a new dataset again since the blast loads satisfy the similarity law,and the proposed NNS method can be directly used to simulate the blast loads generated by different cylindrical charges.The proposed NNS method with high efficiency and accuracy can be used as an effective method to analyze the dynamic response of structures under blast loads,and it has significant application prospects in designing protective structures. 展开更多
关键词 Close-range air blast load Cylindrical charge Numerical method Neural network CEL method CONWEP model
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Multi-QoS routing algorithm based on reinforcement learning for LEO satellite networks 被引量:1
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作者 ZHANG Yifan DONG Tao +1 位作者 LIU Zhihui JIN Shichao 《Journal of Systems Engineering and Electronics》 2025年第1期37-47,共11页
Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To sa... Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To satisfy quality of service(QoS)requirements of various users,it is critical to research efficient routing strategies to fully utilize satellite resources.This paper proposes a multi-QoS information optimized routing algorithm based on reinforcement learning for LEO satellite networks,which guarantees high level assurance demand services to be prioritized under limited satellite resources while considering the load balancing performance of the satellite networks for low level assurance demand services to ensure the full and effective utilization of satellite resources.An auxiliary path search algorithm is proposed to accelerate the convergence of satellite routing algorithm.Simulation results show that the generated routing strategy can timely process and fully meet the QoS demands of high assurance services while effectively improving the load balancing performance of the link. 展开更多
关键词 low Earth orbit(LEO)satellite network reinforcement learning multi-quality of service(QoS) routing algorithm
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Lightweight deep network and projection loss for eye semantic segmentation
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作者 Qinjie Wang Tengfei Wang +1 位作者 Lizhuang Yang Hai Li 《中国科学技术大学学报》 北大核心 2025年第7期59-68,58,I0002,共12页
Semantic segmentation of eye images is a complex task with important applications in human–computer interaction,cognitive science,and neuroscience.Achieving real-time,accurate,and robust segmentation algorithms is cr... Semantic segmentation of eye images is a complex task with important applications in human–computer interaction,cognitive science,and neuroscience.Achieving real-time,accurate,and robust segmentation algorithms is crucial for computationally limited portable devices such as augmented reality and virtual reality.With the rapid advancements in deep learning,many network models have been developed specifically for eye image segmentation.Some methods divide the segmentation process into multiple stages to achieve model parameter miniaturization while enhancing output through post processing techniques to improve segmentation accuracy.These approaches significantly increase the inference time.Other networks adopt more complex encoding and decoding modules to achieve end-to-end output,which requires substantial computation.Therefore,balancing the model’s size,accuracy,and computational complexity is essential.To address these challenges,we propose a lightweight asymmetric UNet architecture and a projection loss function.We utilize ResNet-3 layer blocks to enhance feature extraction efficiency in the encoding stage.In the decoding stage,we employ regular convolutions and skip connections to upscale the feature maps from the latent space to the original image size,balancing the model size and segmentation accuracy.In addition,we leverage the geometric features of the eye region and design a projection loss function to further improve the segmentation accuracy without adding any additional inference computational cost.We validate our approach on the OpenEDS2019 dataset for virtual reality and achieve state-of-the-art performance with 95.33%mean intersection over union(mIoU).Our model has only 0.63M parameters and 350 FPS,which are 68%and 200%of the state-of-the-art model RITNet,respectively. 展开更多
关键词 lightweight deep network projection loss real-time semantic segmentation convolutional neural networks END-TO-END
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