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青藏高原地下水研究现状及主要科学问题
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作者 郭华明 高志鹏 +4 位作者 胡雅璐 邢世平 李遥 蒋小伟 彭建兵 《地学前缘》 北大核心 2026年第1期328-341,共14页
作为“亚洲水塔”的青藏高原,其地下水对于维持长江、黄河、雅鲁藏布江、怒江、澜沧江等亚洲大江大河的流量稳定、保障区域生态系统健康、确保数亿人口用水安全具有不可替代的作用。然而,相对于地表水和冰川冻土,青藏高原地下水研究十... 作为“亚洲水塔”的青藏高原,其地下水对于维持长江、黄河、雅鲁藏布江、怒江、澜沧江等亚洲大江大河的流量稳定、保障区域生态系统健康、确保数亿人口用水安全具有不可替代的作用。然而,相对于地表水和冰川冻土,青藏高原地下水研究十分薄弱。少数研究利用GRACE卫星数据反演,量化了地下水储量变化的发展趋势;部分研究揭示了冻融条件下局部区域地下水动态特征及生态环境效应。本文在对相关文献进行系统梳理的基础上,总结了青藏高原地下水类型及分布和地下水利用现状,粗略估算了地下水储量和地下水资源量,揭示了冰川冻土特殊环境下地下水地表水相互作用规律。最后,提出了青藏高原地下水研究存在的主要科学问题,包括浅表固态液态水转化通量和机制、青藏高原地下水循环深度、青藏高原地下水储量及其变化机制。这些科学问题的解决将提升对特殊气象水文、剧烈起伏地形地貌、复杂地质构造和水文地质条件下地下水赋存规律、循环特征及水热耦合过程等理论认识,进一步丰富水文地质学的理论体系。 展开更多
关键词 冰川 冻土 水资源 含水层 构造运动 地热
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Correlation between movement of tectonicblocks and earthquakes in groups 被引量:12
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作者 范俊喜 马瑾 +1 位作者 刁桂苓 单新建 《地震学报》 CSCD 北大核心 2001年第5期514-522,共9页
The Chinese mainland is divided into some tectonic blocks by nearly NE- and EW-orientated faults. Meanwhile strong earthquakes in the Chinese mainland usually cluster in time and space. We call earthquakes in groups. ... The Chinese mainland is divided into some tectonic blocks by nearly NE- and EW-orientated faults. Meanwhile strong earthquakes in the Chinese mainland usually cluster in time and space. We call earthquakes in groups. Tectonic blocks separated by faults and earthquakes in groups are prominent features of the tectonics of the Chi-nese mainland. Correlation between movement of tectonic blocks and groups of earthquakes is discussed in this paper. The results show that earthquakes in groups often occurred at one or several block boundary faults. The released elastic strain energy is built up in the same periods and around blocks. It means that strong earthquakes in groups are mainly caused by movement of blocks. Four types of block movement are identified based ongroup earthquakes: movement along a single boundary of a block (or a combined blocks), movement of a single block, movement of multi-blocks, and movement in block interiors. If we consider distribution of all strong earthquakes occurred in the Chinese mainland, the movement along a single boundary of a block is more popular one inducing strong earthquakes. But if we only consider earthquakes in groups rather than single earthquakesthe movement of a block dominates among four modes. Statistics with respect to group earthquakes show that the Taihangshan mountain and the North China block are much active in the eastern part of Chinese mainland, and in western part of Chinese mainland the active blocks are Sichuan-Yunnan and the Kunlun-Songpan ones. 展开更多
关键词 成组地震 地块活动方式 中国大陆 地震构造 地震活动 断层
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Eye Movements, Cognitive Processes, and Reading 被引量:6
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作者 Keith Rayner 《心理与行为研究》 2004年第3期482-488,共7页
关键词 eye movements perceptual SPAN INTEGRATION ACROSS SACCADES eye movement control.
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Experimental study on movement of particles in centrifugal impeller 被引量:4
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作者 GU Lei NI Fusheng +1 位作者 XU Liqun LIU Mingxing 《排灌机械工程学报》 EI CSCD 北大核心 2018年第3期191-196,共6页
The slurry pump is the key component of a dredger. Solid particles have strong influence on the performance of a slurry pump. The movement of solid particles in a centrifugal impeller was studied using particle image ... The slurry pump is the key component of a dredger. Solid particles have strong influence on the performance of a slurry pump. The movement of solid particles in a centrifugal impeller was studied using particle image velocimetry(PIV) measurement. The experiments were conducted in a dredging pump model at Hohai University. Some transparent glass spheres with diameter of 0. 2-0. 4 mm were used as solid particles. The concentration and relative velocities of the particles were analyzed to investigate the particle trajectory. The results show that the concentration of the particles on the pressure surfaces of the blades is higher than on the suction surfaces,and the particles tend to move towards the suction surfaces. Moreover,the particles have faster relative velocities than the liquid phase through the flow channels of the impeller. 展开更多
关键词 CENTRIFUGAL IMPELLER movement of PARTICLES concentration relative VELOCITIES particle image velocimetry(PIV)
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Future Directions for Eye Movement Research 被引量:10
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作者 Keith Rayner 《心理与行为研究》 2004年第3期489-496,共8页
It is argued that research on eye movements has now entered a fourth general era. Each of the four eras is briefly reviewed, and research findings related to eye movements during reading, scene perception, and visual ... It is argued that research on eye movements has now entered a fourth general era. Each of the four eras is briefly reviewed, and research findings related to eye movements during reading, scene perception, and visual search are discussed. Future directions for research in each of these areas and research in other domains involving eye movements are also discussed. 展开更多
关键词 eye movements READING SCENE PERCEPTION VISUAL SEARCH information processing tasks.
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Research and application of mechanical models for the whole process of 110 mining method roof structural movement 被引量:12
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作者 BIAN Wen-hui YANG Jun +2 位作者 HE Man-chao ZHU Chun XU Dong-ming 《Journal of Central South University》 SCIE EI CAS CSCD 2022年第9期3106-3124,共19页
For the 110 mining method,it is challenging to accurately calculate the support resistance of the roadway due to the lack of understanding of the dynamic movement of the overlying strata in this method.The consequenti... For the 110 mining method,it is challenging to accurately calculate the support resistance of the roadway due to the lack of understanding of the dynamic movement of the overlying strata in this method.The consequential excessive support results in a significant increase in the cost of roadway support.The authors explored the overlying strata movement and roadway deformation of the gob-entry retaining in the 110 mining method to solve this problem.First,the typical stages of the roof-cutting gob-side entry were defined.Second,the mechanical model and calculation formula of the support resistance on the roof were explored.Then,using numerical simulation software,the starting ranges of the specific supports at different stages were verified and the feasibility of the support scheme was examined.Finally,combined with the field measurement data,the stress and the deformation of the gob roadway at different stages under the influence of two mining processes in the 110 mining method were obtained.The numerical simulation results obtained are consistent with the field test results,providing a theoretical basis for precision support at different stages by the 110 mining method. 展开更多
关键词 110 mining method gob-side entry retaining roof structure movement mechanical model
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Ground movement mechanism in tectonic stress metal mines with steep structure planes 被引量:4
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作者 夏开宗 陈从新 +2 位作者 刘秀敏 郑元 付华 《Journal of Central South University》 SCIE EI CAS CSCD 2017年第9期2092-2104,共13页
When mining metal mines with steep structure planes by the caving method,there is a mechanical model in which the horizontal stress on the rock mass is simplified as a column before surface subsidence.The model is use... When mining metal mines with steep structure planes by the caving method,there is a mechanical model in which the horizontal stress on the rock mass is simplified as a column before surface subsidence.The model is used to deduce critical support load and limiting column length for a given horizontal stress and support pressure.Considering the impact of the column effect,a method is proposed to determine the movement of the ground and caving area in a mine.After surface subsidence,the horizontal stress on a surrounding rock mass can be simplified to a cantilever beam mechanical model.Expressions for its bending fracture length are deduced,and a method is given to determine its stability.On this basis,an explanation for the large ground movement and subsidence scope was given.A case study shows that the damage effect of column and cantilever beam is significant for ground movement in metal-ore mine,and an appropriate correction value should be applied when designing for its angle of ground movements. 展开更多
关键词 mining engineering underground mining ground movement horizontal stress COLUMN cantilever pillar
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Identification of abnormal movement state and avoidance strategy for mobile robots 被引量:2
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作者 蔡自兴 段琢华 +1 位作者 章慧团 于金霞 《Journal of Central South University of Technology》 EI 2006年第6期683-688,共6页
Abnormal movement states for a mobile robot were identified by four multi-layer perceptron. In the presence ot abnormality, avoidance strategies were designed to guarantee the safety of the robot. Firstly, the kinemat... Abnormal movement states for a mobile robot were identified by four multi-layer perceptron. In the presence ot abnormality, avoidance strategies were designed to guarantee the safety of the robot. Firstly, the kinematics of the normal and abnormal movement states were exploited, 8 kinds of features were extracted. Secondly, 4 multi-layer pereeptrons were employed to classify the features for four 4-driving wheels into 4 kinds of states, i.e. normal, blocked, deadly blocked, and slipping. Finally, avoidance strategies were designed based on this. Experiment results show that the methods can identify most abnormal movement states and avoid the abnormality correctly and timely. 展开更多
关键词 mobile robot abnormal movement state avoidance strategy
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What Eye Movements Tell About Identifying Compound Words in Reading and Top-Down Effects in Reading Long Texts 被引量:1
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作者 Jukka Hyn 《心理与行为研究》 2004年第3期497-504,共8页
Two lines of research on eye movements in reading are summarized. One line of research examines how adult readers identify compound words during reading. The other line of research deals with how a specific reading go... Two lines of research on eye movements in reading are summarized. One line of research examines how adult readers identify compound words during reading. The other line of research deals with how a specific reading goal influences the way long expository texts are read. Both lines of research are conducted using Finnish as the source language. With respect to the first research question, it is demonstrated that compound words are recognized either holistically or via their components, depending on the length of the compound word. Readers begin to process whatever information is readily available in the foveal vision(i.e., either the whole-word form or the initial component). The second line of research demonstrates that(1)a specific reading goal is capable of exerting an early effect on readers’ eye fixation patterns,(2)time course analyses based on eye movement patterns can reveal interesting individual differences, and(3)working memory capacity is linked to the efficiency to strategically allocate attention as well as to encode information to and retrieve it from the long-term memory. It is concluded that the eye-tracking technique is an excellent research tool to tap into the workings of the human mind during the comprehension of written texts. 展开更多
关键词 eye movements word recognition COMPOUND WORDS text COMPREHENSION working memory capacity.
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Relay movement control for maintaining connectivity in aeronautical ad hoc networks 被引量:2
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作者 李杰 孙志强 +2 位作者 师博浩 宫二玲 谢红卫 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第4期850-858,共9页
As a new sort of mobile ad hoc network(MANET), aeronautical ad hoc network(AANET) has fleet-moving airborne nodes(ANs) and suffers from frequent network partitioning due to the rapid-changing topology. In this work, t... As a new sort of mobile ad hoc network(MANET), aeronautical ad hoc network(AANET) has fleet-moving airborne nodes(ANs) and suffers from frequent network partitioning due to the rapid-changing topology. In this work, the additional relay nodes(RNs) is employed to repair the network and maintain connectivity in AANET. As ANs move, RNs need to move as well in order to re-establish the topology as quickly as possible. The network model and problem definition are firstly given, and then an online approach for RNs' movement control is presented to make ANs achieve certain connectivity requirement during run time. By defining the minimum cost feasible moving matrix(MCFM), a fast algorithm is proposed for RNs' movement control problem. Simulations demonstrate that the proposed algorithm outperforms other control approaches in the highly-dynamic environment and is of great potential to be applied in AANET. 展开更多
关键词 aeronautical ad hoc network (AANET) mobile ad hoc networks topology control network connectivity movement control
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Comparing the rhythm and frequency of heart,breathing and knee movement in Tai Chi Chuan
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作者 魏珊珊 刘宇 李立 《医用生物力学》 EI CAS CSCD 2009年第S1期150-151,共2页
Background:The basic exercise involved in TCC is a series of individual movements that are linked together in a continuous manner and that flow smoothly from one movement to another.Deep breathing and mental concentra... Background:The basic exercise involved in TCC is a series of individual movements that are linked together in a continuous manner and that flow smoothly from one movement to another.Deep breathing and mental concentration are also required to achieve harmony 展开更多
关键词 Comparing the rhythm and frequency of heart breathing and knee movement in Tai Chi Chuan
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Smoke movement in a tunnel of a running metro train on fire 被引量:4
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作者 周丹 田红旗 +1 位作者 郑晋丽 颜鑫 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第1期208-213,共6页
Research on the distribution of smoke in tunnels is significant for the fire emergency rescue after an operating metro train catches fire. A dynamic grid technique was adopted to research the law of smoke flow diffusi... Research on the distribution of smoke in tunnels is significant for the fire emergency rescue after an operating metro train catches fire. A dynamic grid technique was adopted to research the law of smoke flow diffusion inside the tunnel when the bottom of a metro train was on fire and to compare the effect of longitudinal ventilation modes on the smoke motion when the burning train stopped. Research results show that the slipstream curves around the train obtained by numerical simulation are consistent with experimental data. When the train decelerates, the smoke flow first extends to the tail of the train. With the decrease of the train's speed, the smoke flow diffuses to the head of the train. After the train stops, the slipstream around the train formed in the process of train operation plays a leading role in the smoke diffusion in the tunnel. The smoke flow quickly diffuses to the domain in front of the train. After forward mechanical ventilation is provided, the smoke flow inside the tunnel continues to diffuse downstream. When reverse mechanical ventilation operates, the smoke in front of the train flows back rapidly and diffuses to the rear of the train. 展开更多
关键词 subway tunnel train catching fire moving fire source smoke movement ventilation control
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MASS MOVEMENT AND LANDSLIDE HAZARD, MURREE AREA, NORTH PAKISTAN
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作者 Iftikhar Ahmed Abbasi, M. Asif Khan,Shams ul Hadi(Department and NCE in Geology, University of Peshawar, Pakistan) 《地学前缘》 EI CAS CSCD 2000年第S1期443-443,共1页
The summer resort of Murree and adjoining areas is characterized by high degree of erosivity and erodibility due to both natural and man induced factors. This area is part of a young orogenic belt that is experiencing... The summer resort of Murree and adjoining areas is characterized by high degree of erosivity and erodibility due to both natural and man induced factors. This area is part of a young orogenic belt that is experiencing one of the world’s most rapid uplift rates, and is located in near vicinity of major thrust faults. Shear zones associated with still active faults, such as Murree Thrust and also the folding generated due to thrusting induce an inherited weakness and natural instability potential in the rocks of the Murree Hills. Ever increasing population pressure, deforestation, large\|scale construction works including a new township and a road network have further aggravated the problem. In order to study the landslides and other mass movement related problems in Murree, an area around the main town is selected for detailed analysis of the problem as it has been focus of major development and road construction work. This study is an attempt to prepare a preliminary hazard/landslide map along major road network, around Murree town to identify the unstable areas. Data collection during the fieldwork and its analysis were carried out on Geographic Information System (GIS) based on ILWIS format of the ITC, the Netherlands. Detailed study of a few selected landslides has also been conducted to understand the mechanism of failure and extent of damage. 展开更多
关键词 MASS movement LANDSLIDE HAZARD Murree Area NORTH Pakistan
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THE EXTENSIONAL MOVEMENT AND ACTION IN THE SOUTHERN TIBET SINCE HERCYNIAN
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作者 Wang Genhou,Gao Jinhan,Liang Dingyi(China University of Geosciences, Beijing 100083,China) 《地学前缘》 EI CAS CSCD 2000年第S1期60-61,共2页
Based on the study of the location of extensional action in the tectonic background and the state of regional tectonic stress, the extensional action can be distinguished into active and passive types. The active exte... Based on the study of the location of extensional action in the tectonic background and the state of regional tectonic stress, the extensional action can be distinguished into active and passive types. The active extensional movement is mainly composed of a set of deposition formed under extensional stress and syntectonic and syndepositional deformational structure. The passive extentional movement is expressed as regional extensional action induced under the compressional elevation. Extensional movement and action are well\|developed in the Tibet\|Tethys domain. By the analysis of tectonic deformation, extensional unconformity, depositional facies and paleogeographical rebuilding in the South Tibet, it is recognized that the extensional movement consists of active extension of Hercynian, Indo\|China and Early Yanshan epochs, and the passive extension of Late Yanshan and Himalayan epochs. Some of the characteristics of extensional movement and structures are discussed in this paper(Table.1). 展开更多
关键词 Southern Tibet EXTENSIONAL movement EXTENSIONAL UNCONFORMITY Hercynian—Early Yanshan EPOCH
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STAGES OF THE NEOTECTONIC MOVEMENT IN THE MENYUAN BASIN, QINGHAI PROVINCE
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作者 Ma Baoqi(Dept. of Urban and Environment, Peking Univ., Beijing 100871,China) 《地学前缘》 EI CAS CSCD 2000年第S1期247-247,共1页
The Menyuan Basin is a structural basin located inside the Qilianshan Mountains, the northern edge of Qinghai—Tibet Plateau, the surface of which is about 3000m ASL. To the south of this basin is the Dabanshan Mounta... The Menyuan Basin is a structural basin located inside the Qilianshan Mountains, the northern edge of Qinghai—Tibet Plateau, the surface of which is about 3000m ASL. To the south of this basin is the Dabanshan Mountain and to the north, the Lenglongling Mountain, which are 4000m ASL.. The neotectonic movement within this area is intense and can be divided into 6 stages.1 The basic data for identifying the stages of the neotectonic movement (1) Deformation of Tertiary deposit: Of the Tertiary system, only Baiyanghe Formation exists in the studied area, distributing at the boundary and under the bottom of the basin with Quaternary deposits discontinuously overlying it. Baiyanghe Formation has been intensely offset and folded, the folding dose not appear in Quaternary deposits. Its exact age remains unknown.(2) Deformation of Quaternary deposits: Most of Quaternary deposits belong to glacial and fluvial deposits, which have been offset and uplifted or sunk by neotectonic movement.(3) Deformation of the geomorphic surfaces: In the studied area exist many types and many orders of geomorphic surfaces, including 2 orders of planation surfaces, 3 orders of glacial platforms, 3 orders of river terraces and 2 orders of alluvial fans. Their ages are dated or comparatively estimated. All of them have been offset and uplifted or subsided by neotectonic movement. They are the time scales for dividing the stages of neotectonic movement. 展开更多
关键词 the Menyuan BASIN the STAGES of the NEOTECTONIC movement BAI yanghe Formation QUATERNARY deposits geomorphic surfaces STAGES of FAULTING
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A Theoretic Interpretation of Movement of the Cusp Equatorward Boundary 被引量:2
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作者 J. B. Cao A. Leonovich +3 位作者 G. C. Zhou Z. X. Liu H. Reme I. Dandouras 《空间科学学报》 CAS CSCD 北大核心 2005年第5期412-418,共7页
A preliminary model is proposed to describe quantitatively the position and movement of cusp equatorward boundary. This integrated model, consisting of an empirical model of the magnetopause and a compressed dipolar m... A preliminary model is proposed to describe quantitatively the position and movement of cusp equatorward boundary. This integrated model, consisting of an empirical model of the magnetopause and a compressed dipolar model of Open/Closed field line, connects quantitatively the solar wind conditions, subsolar magnetopause and cusp equatorward boundary. It is shown that the increasing solar wind dynamic pressure and the increasing southward Interplanetary Magnetic Field (IMF) component drive the magnetopause to move inward and the cusp equatorward. This model is adopted to interpret quantitatively the cusp movement of August 14, 2001 observed by Cluster. The results show that the subsolar magnetopause moved earthward from 10.7 Re to 9.0Re during the period of 002300-002800 UT, and correspondingly the cusp equatorward boundary shifted equatorward. The observations of Cluster C1 and C4 show the cusp equatorward boundary that Cluster C1 and C4 were crossing during same interval moved equatorward by 4.6°. The cusp equatorward boundary velocity computed in the theoretical model (10.7 km/s) is in good agreement with the observed value(9.4km/s) calculated from the data of CIS of Cluster C4 and C1. 展开更多
关键词 太阳风 赤道 边界线 磁场
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Chemogenetic activation of sublaterodorsal tegmental glutamatergic neurons alleviates rapid eye movement sleep behavior disorder symptoms in a chronic rat model of Parkinson disease
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作者 DU Li-da XU Lin-hao +3 位作者 LIANg Tuo Yun-Kwok WING KE Ya Wing-Ho YUNG 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2016年第10期1031-1031,共1页
Rapid eye movement(REM)sleep behavior disorder(RBD)is a parasomnia that is featured by elevated motor behaviors and dream enactments during REM sleep.Clinical observations show that RBD bears significant relevance wit... Rapid eye movement(REM)sleep behavior disorder(RBD)is a parasomnia that is featured by elevated motor behaviors and dream enactments during REM sleep.Clinical observations show that RBD bears significant relevance with several synucleinopathies such as Lewy body dementia and Parkinson disease(PD),and often develops prior to their diagnosis.Being a potential biomarker of PD,investigating the relationship of RBD symptoms and their emergence in developing PD would provide insight intoits pathogenesis.Here,in a chronic model of PD,rats with daily rotenone treatment exhibited key RBD features,including elevated sleep muscle tone,sleep fragmentation and EEG slowing at different time points.Based on detectedearly alpha synuclein aggregation and neural apoptosis in the sublaterodorsal tegmental nucleus(SLD),an area known to promote REM sleep and maintain sleep muscle atonia,the possible involvement of SLD glutamatergic neurons was interrogated.Via chemogenetic activation of SLD glutamatergic neurons,key RBD symptoms and EEG slowing in REM sleep were alleviated.These results are consistent with a progressive degeneration in REM sleep promoting pathways.Our findings provide a foundation for further studies into RBD and its relationship to neurodegenerative diseases. 展开更多
关键词 sublaterodorsal tegmental glutamatergic neurons rapid eye movement sleep behavior disorder
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Theoretical Computation of Nonlinear System Equations of Heavier Pellets Movements for Two Phase Flow
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作者 Guo Jinji and Zhan ShengDept. of Applied Mechanics and Engineering, Zhongshan University, Guangzhou 510275, P.RChina 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 1992年第3期59-68,共10页
This paper presents nonlinear ordinary differential equations (ODES) of the heavier pellets movement for two phase flow, which actually represent a system of equations. The usual methods of solution such as Runge -Kut... This paper presents nonlinear ordinary differential equations (ODES) of the heavier pellets movement for two phase flow, which actually represent a system of equations. The usual methods of solution such as Runge -Kutta method and it's datum results are discussed. This paper solves ODES of general form using variable mesh-length, linearizing the nonlinear terms by finite analysis method, fuilding an iteration sequence, and amending the nonlinear terms by iteration . The conditions of convergent operation of iteration solution is checked. The movement orbit and velocity of the pellets are calculated. Analysis of research results and it's application examples are illustrated. 展开更多
关键词 Heavier pellets movement Two phase flow Nonlinear system equations Finite analysis method Iteration approach solutions.
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External Root Resorption During Standardised Orthodontic Tooth Movement In Young And Adult Rats 被引量:2
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作者 RENYi-jin JC.Maltha AMKuijpers-Jagtman 《口腔医学研究》 CAS CSCD 2004年第3期282-285,共4页
目的 :比较研究幼鼠和成年鼠正畸牙齿移动过程中的牙根吸收。方法 :本研究包括两组大鼠 ,其中幼鼠 30只 (年龄约 6周 ) ,成年鼠 30只 (年龄约 912个月 )。大鼠上颌牙一侧用于实验侧 ,另一侧用于对照。实验侧的三颗磨牙用结扎丝颌粘接剂... 目的 :比较研究幼鼠和成年鼠正畸牙齿移动过程中的牙根吸收。方法 :本研究包括两组大鼠 ,其中幼鼠 30只 (年龄约 6周 ) ,成年鼠 30只 (年龄约 912个月 )。大鼠上颌牙一侧用于实验侧 ,另一侧用于对照。实验侧的三颗磨牙用结扎丝颌粘接剂固为一个整体 ,在超弹性拉簧作用下 (力值为 0 .1牛顿 )向切牙侧移动。 1,2 ,4 ,8和 12周时给予大鼠过量麻醉剂 ,材料用于组织学研究。上颌第一磨牙的近中颊侧根为根吸收研究对象。压力侧和张力侧的牙根吸收程度在显微镜下进行长度测量。实验侧与对照侧 ,压力侧与张力侧 ,幼鼠与成年鼠之间的牙根吸收程度分别以实验时间为参照 ,在统计学手段下进行了组间和组内分析和比较 ,以探讨牙齿移动时间和年龄因素对于牙根吸收的影响。结果 :实验侧的牙根吸收在幼鼠与成年鼠之间在 1,2 ,4 ,8周时均没有统计学差异。而在第 12周时 ,成年鼠实验侧牙根吸收大于幼鼠 (P <0 .0 5 )。成年鼠实验组压力侧的牙根吸收明显大于对照组压力侧 ,而在幼鼠组没有发现这一差异。两组年龄幼鼠的实验组其压力侧和张力侧的牙根吸收均高度相关。结论 :相对于对照侧 ,正畸牙齿移动并没有在幼鼠的实验侧诱发更多的牙根吸收。在成年鼠 ,长期的正畸作用力倾向于诱发更多的牙根吸收。这些研究结果表明对于正? 展开更多
关键词 年龄 牙齿移动 牙根吸收 正畸力
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Engineering The Neck Hinge Reshapes The Processive Movement of Kinesin-3
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作者 LI Dong REN Jin-Qi +2 位作者 SONG Yin-Long LIANG Xin FENG Wei 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2024年第10期2730-2740,共11页
Objective In kinesin-3,the neck coil correlates with the following segments to form an extended neck that contains a characteristic hinge diverse from a proline in KIF13B to a long flexible linker in KIF1A.The functio... Objective In kinesin-3,the neck coil correlates with the following segments to form an extended neck that contains a characteristic hinge diverse from a proline in KIF13B to a long flexible linker in KIF1A.The function of this neck hinge for controlling processive movement,however,remains unclear.Methods We made a series of modifications to the neck hinges of KIF13B and KIF1A and tested their movement using a single-molecule motility assay.Results In KIF13B,the insertion of flexible residues before or after the proline differentially impacts the processivity or velocity,while the removal of this proline increases the both.In KIF1A,the deletion of entire flexible neck hinge merely enhances the processivity.The engineering of these hinge-truncated necks of kinesin-3 into kinesin-1 similarly boosts the processive movement of kinesin-1.Conclusion The neck hinge in kinesin-3 controls its processive movement and proper modifications tune the motor motility,which provides a novel strategy to reshape the processive movement of kinesin motors. 展开更多
关键词 intracellular transport molecular motor kinesin-3 neck hinge processive movement
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