In ethanol, the copper(II) complex with the 2′-(2-thienylidene)-h ydroxybenzoylhydrazide, Cu(C12H10N2O2S)2, was synthesized, and it′s structure was characterized by IR, UV and elemental analysis. The single crystal ...In ethanol, the copper(II) complex with the 2′-(2-thienylidene)-h ydroxybenzoylhydrazide, Cu(C12H10N2O2S)2, was synthesized, and it′s structure was characterized by IR, UV and elemental analysis. The single crystal structure has been determined by X-ray diffraction analysis. The crystal belongs to monoclinic system, space group C2/c with cell constants, a=2.273 6(4) nm, b=0.592 12(9) nm, c=1.828 1(3) nm, β=109.735(5)°, V=2.316 4(7) nm3, Z=4, μ=1.164 mm-1, Dc=1.595 g·cm-3, F(000)=1 140, R=0.048 6, wR=0.101 6. In the compound copper(II) atom is four-coordinated with two nitrogen atoms from amide and two oxygen atoms from keto group. Their biological activities have been measused. The results show that the anti-bacterial activity of the coordination compound is much better that of the ligand. CCDC: 272938.展开更多
A new binuclear copper ?complex with 1,10-phen and fluoroquinolone ligands, [Cu2(cfc)2(phen)2(pip)](NO3)2(CO)2,was synthesized and its crystal structure was solved.The formula of the complex is C28H24ClCuFN5O7, <IM...A new binuclear copper ?complex with 1,10-phen and fluoroquinolone ligands, [Cu2(cfc)2(phen)2(pip)](NO3)2(CO)2,was synthesized and its crystal structure was solved.The formula of the complex is C28H24ClCuFN5O7, <IMG SRC="IMAGE/09150030. JPG" HEIGHT=11 WIDTH=12>and the crystallography data are as follows, triclinic, space group , a=0.80372(6)nm, b=0.94712 (7)nm, c=1.67826(13)nm, α=88.5650(10)° , β=80.9920(10)°, γ=70.2780(10)°, V=1.18722(6)nm3, Z=2, D=1.848g·cm-3, F(0 00)=676. R1=0.0627 and wR2=0.1684 (I >2σ(I)). The copper atom is five-coordina te with square-based pyramidal geometry and involves two nitrogen atoms from ph en, two oxygen atoms from cfc and one nitrogen atom from pip anion. The stacking effect between cfc and phen ligands from two neighboring molecules was observed . FT-IR spectrum of the complex was also discussed. Both ligand and complex wer e assayed against gram-positive and gram-negative bacteria by doubling dilutio ns method; the complex shows the same minimal inhibitory concentration (MIC) as the corresponding ligand against S. Aureus, E. Coli and M. Lutens bacteria. The inhibitory effect of the ligand and complex on leukemia HL-60 cell line and liv er cancer BEL-7402 cell line have been measured by using MTT (Methyl-Thiazol- Tetrozolium) and SRB (Sulphurhodamin B) assay methods, respectively. The results indicated that the complex has strong inhibitory effect on HL-60 and BEL-7402 cell line. CCDC: 203964.展开更多
The novel dinuclear copper(Ⅱ) complex with with N (2,4 dihydroxybenzalidene) o aminobenzoic acid ligand, [Cu(C14H9NO4)]2· 2H2O, has been synthesized and characterized by elemental analysis, IR, UV Vis and therma...The novel dinuclear copper(Ⅱ) complex with with N (2,4 dihydroxybenzalidene) o aminobenzoic acid ligand, [Cu(C14H9NO4)]2· 2H2O, has been synthesized and characterized by elemental analysis, IR, UV Vis and thermal analysis. Its crystal structure was determined by single crystal X ray diffraction techniques. The crystal belongs to monoclinic with space group P21/c. The cell parameters are: a=0.82510(11)nm, b=0.68870(9)nm, c=2.3007(3)nm, β =100.847(2)° , V=1.2840(3)nm3, Z=2, Dc=1.742Mg· m- 3, μ (MoKα )=1.723mm- 1, F(000)=684. The structure was refined to final R1=0.0267, wR2=0.0735. The complex molecule structure has dinuclear centrosymmetric dimeric structure in which a planar Cu2O2 core features. The ligand N (2,4 dihydroxybenzalidene) o aminobenzoic acid dianion is μ 2 tridentate, chelating one copper? ion via one nitrogen, one hydroxy oxygen atom and one carboxylate oxygen atom, and the hydroxy oxygen atom simultaneously coordinates to the other copper? ion of the dimer. In the structure the copper? ion rendered four coordination in a distorted square planar geometry structure. CCDC: 212695.展开更多
A new complex hexaaquamagnesium(Ⅱ) bis [2-(thiosemicarbazonomethyl)-benzoato],has been prepared and characterized by elemental analysis,IR spectra,molar conductivity and single-crystal X-ray diffraction. The results ...A new complex hexaaquamagnesium(Ⅱ) bis [2-(thiosemicarbazonomethyl)-benzoato],has been prepared and characterized by elemental analysis,IR spectra,molar conductivity and single-crystal X-ray diffraction. The results of crystal structure show that each Mg(Ⅱ) ion is coordinated with six oxygen atoms from water molecules and the complex formed two dimensional layered structure through intramolecule and intermolecule hydrogen bonds. The antibacterial assay of the magnesium(Ⅱ) complex and the ligand were tested using a modified version of the 2-fold serial dilution method,the results show that the complex show considerable antibacterial activity against escherichia coli,bacillus subtilis and staphylococcus white,and the ligand did not show antibacterial activity.展开更多
文摘In ethanol, the copper(II) complex with the 2′-(2-thienylidene)-h ydroxybenzoylhydrazide, Cu(C12H10N2O2S)2, was synthesized, and it′s structure was characterized by IR, UV and elemental analysis. The single crystal structure has been determined by X-ray diffraction analysis. The crystal belongs to monoclinic system, space group C2/c with cell constants, a=2.273 6(4) nm, b=0.592 12(9) nm, c=1.828 1(3) nm, β=109.735(5)°, V=2.316 4(7) nm3, Z=4, μ=1.164 mm-1, Dc=1.595 g·cm-3, F(000)=1 140, R=0.048 6, wR=0.101 6. In the compound copper(II) atom is four-coordinated with two nitrogen atoms from amide and two oxygen atoms from keto group. Their biological activities have been measused. The results show that the anti-bacterial activity of the coordination compound is much better that of the ligand. CCDC: 272938.
文摘A new binuclear copper ?complex with 1,10-phen and fluoroquinolone ligands, [Cu2(cfc)2(phen)2(pip)](NO3)2(CO)2,was synthesized and its crystal structure was solved.The formula of the complex is C28H24ClCuFN5O7, <IMG SRC="IMAGE/09150030. JPG" HEIGHT=11 WIDTH=12>and the crystallography data are as follows, triclinic, space group , a=0.80372(6)nm, b=0.94712 (7)nm, c=1.67826(13)nm, α=88.5650(10)° , β=80.9920(10)°, γ=70.2780(10)°, V=1.18722(6)nm3, Z=2, D=1.848g·cm-3, F(0 00)=676. R1=0.0627 and wR2=0.1684 (I >2σ(I)). The copper atom is five-coordina te with square-based pyramidal geometry and involves two nitrogen atoms from ph en, two oxygen atoms from cfc and one nitrogen atom from pip anion. The stacking effect between cfc and phen ligands from two neighboring molecules was observed . FT-IR spectrum of the complex was also discussed. Both ligand and complex wer e assayed against gram-positive and gram-negative bacteria by doubling dilutio ns method; the complex shows the same minimal inhibitory concentration (MIC) as the corresponding ligand against S. Aureus, E. Coli and M. Lutens bacteria. The inhibitory effect of the ligand and complex on leukemia HL-60 cell line and liv er cancer BEL-7402 cell line have been measured by using MTT (Methyl-Thiazol- Tetrozolium) and SRB (Sulphurhodamin B) assay methods, respectively. The results indicated that the complex has strong inhibitory effect on HL-60 and BEL-7402 cell line. CCDC: 203964.
文摘The novel dinuclear copper(Ⅱ) complex with with N (2,4 dihydroxybenzalidene) o aminobenzoic acid ligand, [Cu(C14H9NO4)]2· 2H2O, has been synthesized and characterized by elemental analysis, IR, UV Vis and thermal analysis. Its crystal structure was determined by single crystal X ray diffraction techniques. The crystal belongs to monoclinic with space group P21/c. The cell parameters are: a=0.82510(11)nm, b=0.68870(9)nm, c=2.3007(3)nm, β =100.847(2)° , V=1.2840(3)nm3, Z=2, Dc=1.742Mg· m- 3, μ (MoKα )=1.723mm- 1, F(000)=684. The structure was refined to final R1=0.0267, wR2=0.0735. The complex molecule structure has dinuclear centrosymmetric dimeric structure in which a planar Cu2O2 core features. The ligand N (2,4 dihydroxybenzalidene) o aminobenzoic acid dianion is μ 2 tridentate, chelating one copper? ion via one nitrogen, one hydroxy oxygen atom and one carboxylate oxygen atom, and the hydroxy oxygen atom simultaneously coordinates to the other copper? ion of the dimer. In the structure the copper? ion rendered four coordination in a distorted square planar geometry structure. CCDC: 212695.
文摘A new complex hexaaquamagnesium(Ⅱ) bis [2-(thiosemicarbazonomethyl)-benzoato],has been prepared and characterized by elemental analysis,IR spectra,molar conductivity and single-crystal X-ray diffraction. The results of crystal structure show that each Mg(Ⅱ) ion is coordinated with six oxygen atoms from water molecules and the complex formed two dimensional layered structure through intramolecule and intermolecule hydrogen bonds. The antibacterial assay of the magnesium(Ⅱ) complex and the ligand were tested using a modified version of the 2-fold serial dilution method,the results show that the complex show considerable antibacterial activity against escherichia coli,bacillus subtilis and staphylococcus white,and the ligand did not show antibacterial activity.
