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Acute Inflammatory Pain Induces Sex-different Brain Alpha Activity in Anesthetized Rats Through Optically Pumped Magnetometer Magnetoencephalography
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作者 MIAO Meng-Meng REN Yu-Xuan +5 位作者 WU Wen-Wei ZHANG Yu PAN Chen LIN Xiang-Hong LIN Hui-Dan CHEN Xiao-Wei 《生物化学与生物物理进展》 北大核心 2025年第1期244-257,共14页
Objective Magnetoencephalography(MEG),a non-invasive neuroimaging technique,meticulously captures the magnetic fields emanating from brain electrical activity.Compared with MEG based on superconducting quantum interfe... Objective Magnetoencephalography(MEG),a non-invasive neuroimaging technique,meticulously captures the magnetic fields emanating from brain electrical activity.Compared with MEG based on superconducting quantum interference devices(SQUID),MEG based on optically pump magnetometer(OPM)has the advantages of higher sensitivity,better spatial resolution and lower cost.However,most of the current studies are clinical studies,and there is a lack of animal studies on MEG based on OPM technology.Pain,a multifaceted sensory and emotional phenomenon,induces intricate alterations in brain activity,exhibiting notable sex differences.Despite clinical revelations of pain-related neuronal activity through MEG,specific properties remain elusive,and comprehensive laboratory studies on pain-associated brain activity alterations are lacking.The aim of this study was to investigate the effects of inflammatory pain(induced by Complete Freund’s Adjuvant(CFA))on brain activity in a rat model using the MEG technique,to analysis changes in brain activity during pain perception,and to explore sex differences in pain-related MEG signaling.Methods This study utilized adult male and female Sprague-Dawley rats.Inflammatory pain was induced via intraplantar injection of CFA(100μl,50%in saline)in the left hind paw,with control groups receiving saline.Pain behavior was assessed using von Frey filaments at baseline and 1 h post-injection.For MEG recording,anesthetized rats had an OPM positioned on their head within a magnetic shield,undergoing two 15-minute sessions:a 5-minute baseline followed by a 10-minute mechanical stimulation phase.Data analysis included artifact removal and time-frequency analysis of spontaneous brain activity using accumulated spectrograms,generating spectrograms focused on the 4-30 Hz frequency range.Results MEG recordings in anesthetized rats during resting states and hind paw mechanical stimulation were compared,before and after saline/CFA injections.Mechanical stimulation elevated alpha activity in both male and female rats pre-and post-saline/CFA injections.Saline/CFA injections augmented average power in both sexes compared to pre-injection states.Remarkably,female rats exhibited higher average spectral power 1 h after CFA injection than after saline injection during resting states.Furthermore,despite comparable pain thresholds measured by classical pain behavioral tests post-CFA treatment,female rats displayed higher average power than males in the resting state after CFA injection.Conclusion These results imply an enhanced perception of inflammatory pain in female rats compared to their male counterparts.Our study exhibits sex differences in alpha activities following CFA injection,highlighting heightened brain alpha activity in female rats during acute inflammatory pain in the resting state.Our study provides a method for OPM-based MEG recordings to be used to study brain activity in anaesthetized animals.In addition,the findings of this study contribute to a deeper understanding of pain-related neural activity and pain sex differences. 展开更多
关键词 MAGNETOENCEPHALOGRAPHY PAIN sex differences alpha activity INFLAMMATION
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ICRP PUBLICATION 60 HOW MUCH SCIENCE, HOW MUCH JUDGEMENT? REFLECTIONS ON A FEW DIFFERENT ISSUES 被引量:2
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作者 Charles Meinhold(National Council on Radiation Protection and Measurements,USA) 《辐射防护》 CAS CSCD 北大核心 1998年第Z1期13-19,共7页
AnimportantobjectiveoftheCommisionistheprovisionofscientificalybasedrecommendationsthatmeritwidespreadacepta... AnimportantobjectiveoftheCommisionistheprovisionofscientificalybasedrecommendationsthatmeritwidespreadaceptance.Intodaysshri... 展开更多
关键词 ICRP PUBLICATION HOW MUCH ISSUES different FEW
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Relationship between the stoichiometric characteristics and leaf functional traits of Castanopsis hystrix in different ages 被引量:1
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作者 Zhang Zhongrui Qi Ye +5 位作者 Ding Xiaogang Yang Haiyan Wei Dan Zhang Geng Zhu Hangyong Chen Li 《林业与环境科学》 2020年第2期1-6,共6页
Both the stoichiometric characteristics and leaf functional traits can reflect the adaptability of plants to changes in the external living environment.In particular,for varying aged forest plants,the study of stoichi... Both the stoichiometric characteristics and leaf functional traits can reflect the adaptability of plants to changes in the external living environment.In particular,for varying aged forest plants,the study of stoichiometric characteristics and leaf functional traits can reflect the plant’s life history strategy and its resource investment and allocation methods.In this paper,the 1.5-year-old,5-year-old,15-year-old and 20-year-old Castanopsis hystrix were selected as the research objects to investigate the trends of stoichiometry and leaf functional traits,and their synergistic changes were verified.The results showed that with the increase of age,the stability of C.hystrix stoichiometry gradually increased,and the functional traits also tended to invest in security.However,there was no synergistic change between the two,which might be attributed to the different sensitivity of the C.hystrix leaf to the environment at the life history level of 1.5-year-old to 20-year-old. 展开更多
关键词 CASTANOPSIS HYSTRIX different age STOICHIOMETRY LEAF functional TRAITS
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Local Shear Stresses Elicit Different Mechanical Response and Gene Expression from Complex Stresses
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作者 Fuxiang Wei Cunyu Zhang +1 位作者 Yawen Liao Ning Wang 《医用生物力学》 EI CAS CSCD 北大核心 2019年第A01期147-147,共1页
It is well established that living cells and tissues respond to mechanical forces such as flow-related shear stresses in blood or interstitial space and complex tractional stresses at cell-matrix contacts and cell-cel... It is well established that living cells and tissues respond to mechanical forces such as flow-related shear stresses in blood or interstitial space and complex tractional stresses at cell-matrix contacts and cell-cell contacts.However,how different modes of forces impact mechanical and biological responses is elusive.Here we describe a strategy of using the three-dimensional magnetic twisting cytometry(3D MTC)technology to apply forces in any desired directions to the same living cell.We reveal that for a fixed stress amplitude and frequency,a live cell exhibits mechanical anisotropy and responds to a local shear stress differently from responding to a local complex stress by stretching chromatin and upregulating gene transcription to different levels,extending our previous finding on force-induced direct gene activation.This finding highlights the importance of force modes in impacting cellular mechanical and biological responses in living cells and tissues and may have implications in tissue patterning and embryonic development. 展开更多
关键词 LOCAL SHEAR Stresses Elicit different Mechanical Response GENE EXPRESSION Complex Stresses
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The study of the safety and efficacy of different antithrombotic therapy after left atrial appendage closure
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作者 Xia Yu Hao Zhang Pihua Fang 《中国循环杂志》 CSCD 北大核心 2018年第S01期156-156,共1页
Background It’s essential to prevent from thrombosis on device without increasing the risk of bleeding complications after successfully implanted left atrial appendage device.At present,no guidelines recommend about ... Background It’s essential to prevent from thrombosis on device without increasing the risk of bleeding complications after successfully implanted left atrial appendage device.At present,no guidelines recommend about postoperative antithrombotic therapy of left atrial appendage closure(LAAC).The purpose of this study is to investigate the safety and efficacy of different antithrombotic therapies after LAAC. 展开更多
关键词 different ANTITHROMBOTIC therapy LEFT ATRIAL appendage CLOSURE risk
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Perioperative outcomes of different temperature management in pediatric aortic arch surgery:a single center 8-year experience
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作者 Yuanyuan Tong Jinping Liu +1 位作者 Ruoning Lv Yu Jin 《中国循环杂志》 CSCD 北大核心 2018年第S01期171-171,共1页
Objective With the widespread application of regional low flow perfusion, deep hypothermia is non-essential for organ protection;therefore, there is a growing tendency to increase systemic temperature.
关键词 different TEMPERATURE low flow PERFUSION INCREASE SYSTEMIC TEMPERATURE
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Weights of Different Multipole Interactions in Low Temperature Fast Reactions
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作者 Tan Xiaofeng Dong Feng Li XuechuState key laboratory of molecular dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, PRC 《原子与分子物理学报》 CAS CSCD 北大核心 1998年第S1期179-180,共2页
Studiesofdiatomdiatomfastreactionplayaveryimportantroleinunderstandingthenatureofchemicalreactions.Itisalsoa... Studiesofdiatomdiatomfastreactionplayaveryimportantroleinunderstandingthenatureofchemicalreactions.Itisalsoaveryactivefieldt... 展开更多
关键词 INTERACTIONS LOW WEIGHTS different
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Effects of Three Different Diluents on Quality of Boar Semen Stored at 17℃
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作者 Hu Shan Zhang Xiao-gang +4 位作者 Han Cong Wei Shuai-yi Xie Dong-qi Du Ren-rang Hu Jian-hong 《Journal of Northeast Agricultural University(English Edition)》 CAS 2015年第2期36-46,共11页
To investigate the effects of different diluents on the quality of the boar semen stored at 17℃, and assess the relationship between sperm motility and the relative levels of enzymes, three commercial diluents (Dilu... To investigate the effects of different diluents on the quality of the boar semen stored at 17℃, and assess the relationship between sperm motility and the relative levels of enzymes, three commercial diluents (Diluent I, Diluent II and Diluent III) and three boar breed semens (Yorkshire, Landrace and Duroc) were utilized. The sperm motility, effective survival time, survival index, catalase (CAT), the total anti-oxidative capacity (T-AOC) and malondialdehyde (MDA) levels were evaluated. The results showed that there were significant interaction effects between diluents and breeds on the boar sperm motility (P〈0.001), survival time (P〈0.001), CAT levels (P〈0.001) and T-AOC levels (P〈0.001), but neither effects nor interaction effects between diluents and breeds on survival index (P〉0.05). All of the parameters varied significantly with the increase of the storage time (P〈0.001). The survival time increased 12.9% in Yorkshire boar semen diluted with Diluent III than with Diluent II, while the survival time increased 6.6% in Landrace boar semen diluted with Diluent II than with Diluent III. Both CAT and T-AOC levels were significantly positive correlated with sperm motility in all the three boar breeds (P〈0.001), while MDA levels were significantly negative correlated with sperm motility (P〈0.001). These results indicated that Diluent III and Diluent II were the optimal commercial diluents for Yorkshire and Landrace boar semen stored at 17 ℃, respectively. 展开更多
关键词 boar semen STORAGE different diluents survival index enzyme activity
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Effect of Different Treatment Rapeseeds on Activity of Cellulose Enzyme in Sheep
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作者 JIN Long ZHANG Yonggen TAN Weizhuo LIU Wei 《Journal of Northeast Agricultural University(English Edition)》 CAS 2010年第1期57-61,共5页
The purpose of the experiment is to research the effect of different rapeseed treatments feeding on activity of cellulose enzyme in sheep. Eight male adults of semi-fine wool sheep breeds with the same weight and perm... The purpose of the experiment is to research the effect of different rapeseed treatments feeding on activity of cellulose enzyme in sheep. Eight male adults of semi-fine wool sheep breeds with the same weight and permanent rurnen cannulas were selected according to 4×4 Latin square design to determine the effect of different rapeseed treatment groups including crushed rapeseed, whole rapeseed, extruded rapeseed (dietary lipid content of =67 g·kg^-1) and control group (dietary lipid content of =30 g·kg^-1) on activity dynamic variation of ruminal celluolytic enzyme in sheep. The results showed that ruminal fluid pH matched up to the condition of fiber degradation and growth of cellulolytic bacterium when fed four diets; but there was significant difference (P〈0.05) for the activity of microcrystalline cellulose, glucanase, salicin enzyme involved in ruminal fiber degradation after fed 2, 4, 6 h. 展开更多
关键词 RAPESEED different treatments SHEEP cellulose enzyme
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Influence of the Different Level Ammonium on NRA and GSA in Sugar Beet(Vulgaris L.)
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作者 ZHAOYue WEIZi-min +1 位作者 MAFeng-ming WANGLian-jun 《Journal of Northeast Agricultural University(English Edition)》 CAS 2003年第1期88-91,共4页
Ammonium nitrogen inhibited NR activity in sugar beet,NR activity was lower in endogenous substrate after ammonium nitrogen was used,and the correlation between NR activity and ammonium nitrogen levels was negative.Bu... Ammonium nitrogen inhibited NR activity in sugar beet,NR activity was lower in endogenous substrate after ammonium nitrogen was used,and the correlation between NR activity and ammonium nitrogen levels was negative.But NR activity raised with the ammonium nitrogen levels raising in exogenous.Ammonium nitrogen prompted GS activity:the correlation between GS activity and ammonium nitrogen was positive,GS activity raised with ammonium nitrogen levels raising,GS activity of roots and leaves had same change trend in sugar beet in the whole growth duration after ammonium nitrogen was used,but GS activity in roots was higher than that in leaves. 展开更多
关键词 sugar beet different level ammonium NRA GSA
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Effect of Different Roughages on Milk Protein and Milk Fat Synthesis in Dairy Cows
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作者 Sha Shan-shan Zhang Na Li Qing-zhang 《Journal of Northeast Agricultural University(English Edition)》 CAS 2016年第4期40-46,共7页
The main purpose of this study was to determine the effect of a corn straw or mixed diet on milk production, milk composition and the expression of genes associated with lactation in mid-lactation Chinese Holstein cow... The main purpose of this study was to determine the effect of a corn straw or mixed diet on milk production, milk composition and the expression of genes associated with lactation in mid-lactation Chinese Holstein cows. In this study, 10 healthy Chinese Holstein cows were randomly assigned to two groups and fed with different diets respectively, corn straw (CS) or mixed forage (MF) diet. CS group was fed roughage consisting of 53.8% corn straw only and the forge to concentrate (F : C) ratio [dry matter (DM)] was about 40: 60. MF group was fed roughage consisting of 3.7% Chinese wildrye and 23.4% alfalfa hay, the forge to concentrate (F : C) ratio (DM) was 70: 30. All the cows were fed 8 weeks and body weight, dry matter intake, body condition score, fat, protein, lactose, milk yield, total solid and somatic cell count (SCC) were recorded. Quantitative real-time PCR (qRT-PCR) was used to analyze cow mammary gland samples representing two different diets. The results suggested that different diet types had significant effects on milk yield, lactose, milk fat, milk protein, dry matter intake and somatic cell count in dairy cows, and cows fed MF diet improved milk production and lactation performance clearly (P〈0.05). In addition, mRNA expression of genes ACC, roTOR, STATS, CSN2, PPAR),, FABP3 and PTEN in MF group was extremely significantly higher than that in CS group (P〈0.05). mRNA expression ofAKT1, FAS, SCD and SREBPlc in MF group was significantly higher than that in CS group (P〈0.01). In summary, the milk yield and composition in mixed forage group were significantly improved than those in corn straw group. 展开更多
关键词 dairy cow different roughages milk production milk composition
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Development of Bovine Embryos from Two Different Activated-time Oocytes for Parthenogenesis and Two Kinds of Nucleus Donors for Cloning
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《Journal of Northeast Agricultural University(English Edition)》 CAS 1999年第1期79-79,共1页
TheaimofExperiment1wastocomparetheefectoftwodiferentactivatingtimeonparthenogeneticembryonicdevelopment.Oocy... TheaimofExperiment1wastocomparetheefectoftwodiferentactivatingtimeonparthenogeneticembryonicdevelopment.Oocyteswhichwereaspir... 展开更多
关键词 Activated-time different OOCYTES
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Genotypic Resistance of F_1 Cotton Hybrids by Inoculation with Different Virulent Isolates of the Fungus Verticillium Dahliae Klebahn
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作者 AMANTURDIEV Alisher KIM Robert 《棉花学报》 CSCD 北大核心 2008年第S1期107-,共1页
The plant pathogen Verticillium dahliae causes severe cotton losses in Uzbekistan. To create cotton varieties that are resistant to the more virulent races of V.dahliae we wanted to determine
关键词 Genotypic Resistance of F1 Cotton Hybrids by Inoculation with different Virulent Isolates of the Fungus Verticillium Dahliae Klebahn
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美国《保健物理》(Health Physics)杂志英文摘要(2025年128卷第6期)
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《辐射防护》 北大核心 2025年第5期539-544,共6页
Evaluation of Gamma Index Analysis for Detecting Errors in Patient-specific Quality Assurance in Intensity Modulated Radiotherapy Taylan Tugrul1(1.Department of Radiation Oncology,Medicine Faculty of Van Yüzü... Evaluation of Gamma Index Analysis for Detecting Errors in Patient-specific Quality Assurance in Intensity Modulated Radiotherapy Taylan Tugrul1(1.Department of Radiation Oncology,Medicine Faculty of Van YüzüncüYıl University,Van,Turkey)Abstract:Quality assurance practices performed before treatment are believed to identify various potential errors.In this study,2-dimensional(2D)dosimetric results were analyzed by making some intentional mistakes in six different treatment plans.In this way,the detectability of errors was investigated.In all segments of all treatment plans,one of the multileaf collimators was kept fixed at different positions on the central axis.In addition to multileaf collimators error,gantry error was also examined in the study.The dose distribution results obtained by Treatment Planning System(TPS)were compared with those obtained by the 2D array device,both as local calculation and global calculation methods,using the gamma analysis method.When the results are examined in the case where the Multi-leaf collimators(MLC)is fixed at the 1 cm position. 展开更多
关键词 making some intentional mistakes six different treatment plansin multileaf collimators patient specific quality assurance gantry error intensity modulated radiotherapy assurance practices gamma index analysis
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薏苡种仁主要脂质组分分类及特征分子筛选
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作者 李祥栋 陆秀娟 +7 位作者 潘虹 魏心元 曾涛 郭超 陆平 周美亮 高爱农 石明 《中国粮油学报》 北大核心 2025年第4期41-48,共8页
脂质是薏苡的重要营养和功能组分,也是薏苡天然产物开发的重要物质基础。研究以代谢组学方法剖析薏苡种仁脂类物质的分类和组成特征,为薏苡生理活性物质的挖掘利用提供科学支撑。以6份薏苡品种资源为实验材料,采用液相色谱和串联质谱(LC... 脂质是薏苡的重要营养和功能组分,也是薏苡天然产物开发的重要物质基础。研究以代谢组学方法剖析薏苡种仁脂类物质的分类和组成特征,为薏苡生理活性物质的挖掘利用提供科学支撑。以6份薏苡品种资源为实验材料,采用液相色谱和串联质谱(LC-MS/MS)技术对薏苡种仁的脂质组分进行全面检测。研究结果显示,6份薏苡种仁中共检测到552个脂质分子,所有脂质分子根据结构特征分为5个大类和28个亚类。甘油二酯(DG)、甘油三脂(TG)和游离脂肪酸(FFA)为薏苡脂质的主要组成亚类,三者占全部脂质含量的99.69%,以长链和不饱和脂质为主,而且栽培型薏苡的总脂质和主要脂质组分含量均优于野生资源。差异分析结果显示,共有87个脂质分子含量在不同品种类型之间存在显著差异,其中油酸(十八烯酸)、棕榈酸(十六烷酸)、二糖甘油二酯、甘油二酯、单甘油酯和溶血磷脂酰胆碱等9个差异分子在不同品种中含量相对较高,可作为薏苡种仁脂质组分的重要标记分子和功能组分的开发利用。 展开更多
关键词 脂质组 组成差异 功能分子 薏苡
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基于DEMATEL和TOPSIS的低空安防系统方案多属性评价方法 被引量:1
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作者 施玮 吴坚 《科学技术与工程》 北大核心 2025年第14期6109-6117,共9页
针对低空经济发展涉及的安全管理问题,在总结低空经济相关技术路线原理及落地方案的运行经验,分析低空安防普适性的4个建设方案:雷达与通感一体技术融合方案、广播式自动相关监视技术方案、远程识别技术方案和基于TDOA(time difference ... 针对低空经济发展涉及的安全管理问题,在总结低空经济相关技术路线原理及落地方案的运行经验,分析低空安防普适性的4个建设方案:雷达与通感一体技术融合方案、广播式自动相关监视技术方案、远程识别技术方案和基于TDOA(time difference of arrival)无线电技术的多源融合方案的基础上,构建无人飞行器探测技术评价指标体系,并建立了一种基于决策试验评估实验室(decision-making trial and evaluation laboratory, DEMATEL)和优劣解距离法(technique for order preference by similarity to an ideal solution, TOPSIS)的多属性评价方法。结果发现,以TDOA为基础的多源融合方案是构建城市低空安防体系的有效路径和普适性方案。研究表明,低空安防体系的建设是一个系统性工程,需要政府、企业和社会各方的共同努力,在技术、数据、运营等多个层面进行整合,以适应未来低空经济的发展需求。 展开更多
关键词 低空经济 低空安防系统 多属性评价方法 TDOA(time difference of arrival)技术 无人机管控
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Analysis of the effect of vibration on the homogeneity of the kinematic mechanism of an angular mirror translational interferometer
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作者 XU Xue-Rong PENG Yi-Tian +1 位作者 GU Ming-Jian JIANG Teng-teng 《红外与毫米波学报》 北大核心 2025年第3期425-430,共6页
The effect of external vibration on the velocity uniformity of the moving mechanism of the angular mir⁃ror translational Fourier transform interferometer(hereinafter referred to as interferometer)can be quantitatively... The effect of external vibration on the velocity uniformity of the moving mechanism of the angular mir⁃ror translational Fourier transform interferometer(hereinafter referred to as interferometer)can be quantitatively analysed by the interferometer optical range difference velocity stability.The article proposes a more comprehen⁃sive method of analysing the optical range difference velocity uniformity for the reliability of the interferometer ki⁃nematic mechanism under the influence of on-orbit microvibration in the process of space spectroscopy detection.The method incorporates the structural response of the interferometer caused by external excitation into the stabili⁃ty analysis as one of the influencing factors,so as to reflect the reliability of the interferometer in orbit more realis⁃tically,and judge the microvibration criticality that the interferometer can withstand more accurately.At the same time,an optical surface model of the interferometer is established to further theoretically characterise the effect of microvibration on the homogeneity of the interferometric mechanism.The method discussed in the article pro⁃vides a way of thinking for the judgement of the reliability of the mechanism movement under the external excita⁃tion perturbation as well as the research on the optimisation of the mechanism control. 展开更多
关键词 Fourier-interferometer optical range difference velocity stability TREMOR space spectroscopy detection
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Study on Color Difference of Color Reproduction of 3D Objects
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作者 GU Chong DENG Yi-qiang 《印刷与数字媒体技术研究》 北大核心 2025年第4期33-38,69,共7页
To investigate the applicability of four commonly used color difference formulas(CIELAB,CIE94,CMC(1:1),and CIEDE2000)in the printing field on 3D objects,as well as the impact of four standard light sources(D65,D50,A,a... To investigate the applicability of four commonly used color difference formulas(CIELAB,CIE94,CMC(1:1),and CIEDE2000)in the printing field on 3D objects,as well as the impact of four standard light sources(D65,D50,A,and TL84)on 3D color difference evaluations,50 glossy spheres with a diameter of 2cm based on the Sailner J4003D color printing device were created.These spheres were centered around the five recommended colors(gray,red,yellow,green,and blue)by CIE.Color difference was calculated according to the four formulas,and 111 pairs of experimental samples meeting the CIELAB gray scale color difference requirements(1.0-14.0)were selected.Ten observers,aged between 22 and 27 with normal color vision,were participated in this study,using the gray scale method from psychophysical experiments to conduct color difference evaluations under the four light sources,with repeated experiments for each observer.The results indicated that the overall effect of the D65 light source on 3D objects color difference was minimal.In contrast,D50 and A light sources had a significant impact within the small color difference range,while the TL84 light source influenced both large and small color difference considerably.Among the four color difference formulas,CIEDE2000 demonstrated the best predictive performance for color difference in 3D objects,followed by CMC(1:1),CIE94,and CIELAB. 展开更多
关键词 Color difference formula 3D objects Light source Gray scale Normalized residual sum of squares
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Gender differences in the burden of near vision loss in China:An analysis based on GBD 2021 data
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作者 LIU Yu ZHU Liping +4 位作者 LIN Yanhui WANG Yanbing XIONG Kun LI Xuhong YAN Wenguang 《中南大学学报(医学版)》 北大核心 2025年第6期1030-1041,共12页
Objective:Near vision loss(NVL)is one of the leading causes of visual impairment worldwide,exerting a profound impact on individual quality of life and socio-economic development.This study aims to analyze the burden ... Objective:Near vision loss(NVL)is one of the leading causes of visual impairment worldwide,exerting a profound impact on individual quality of life and socio-economic development.This study aims to analyze the burden of NVL in China by sex and age groups from 1990 to 2021 and to project trends over the next 15 years.Methods:Using data from the Global Burden of Disease(GBD)2021 database,we conducted descriptive analyses of NVL prevalence in China,calculated age-standardized prevalence rates(ASPR)and age-standardized disability-adjusted life years rates(ASDR)to compare burden differences between sexes and age groups,and applied an autoregressive integrated moving average(ARIMA)model to predict NVL trends for the next 15 years.The model selection was based on best-fit criteria to ensure reliable projections.Results:From 1990 to 2021,China’s ASPR of NVL rose from 10096.24/100000 to 15624.54/100000,and ASDR increased from 101.75/100000 to 158.75/100000.In 2021,ASPR(16551.70/100000)and ASDR(167.69/100000)were higher among females than males(14686.21/100000 and 149.76/100000,respectively).China ranked highest globally in both NVL cases and disability-adjusted life years(DALYs),with female burden significantly exceeding male burden.Projections indicated this trend and sex gap will persist until 2036.Compared with 1990,the prevalence cases and DALYs increased by 239.20%and 238.82%,respectively in 2021,with the highest burden among females and the 55−59 age group.The ARIMA model predicted continued increases in prevalence and DALYs by 2036,with females maintaining a higher burden than males.Conclusion:This study reveals a marked increase in the NVL burden in China and predicts continued growth in the coming years.Public health policies should prioritize NVL prevention and control,with special attention to women and middle-aged populations to mitigate long-term societal and health impacts. 展开更多
关键词 China near vision loss Global Burden of Disease database autoregressive integrated moving average model gender differences
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A Fast Algorithm for Solving the Poisson Equations Based on the Discrete Cosine/Sine Transforms in the Finite Difference Method
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作者 LI Congcong WANG Danxia +1 位作者 JIA Hongen ZHANG Chenhui 《应用数学》 北大核心 2025年第3期651-669,共19页
To enhance the computational efficiency of spatio-temporally discretized phase-field models,we present a high-speed solver specifically designed for the Poisson equations,a component frequently used in the numerical c... To enhance the computational efficiency of spatio-temporally discretized phase-field models,we present a high-speed solver specifically designed for the Poisson equations,a component frequently used in the numerical computation of such models.This efficient solver employs algorithms based on discrete cosine transformations(DCT)or discrete sine transformations(DST)and is not restricted by any spatio-temporal schemes.Our proposed methodology is appropriate for a variety of phase-field models and is especially efficient when combined with flow field systems.Meanwhile,this study has conducted an extensive numerical comparison and found that employing DCT and DST techniques not only yields results comparable to those obtained via the Multigrid(MG)method,a conventional approach used in the resolution of the Poisson equations,but also enhances computational efficiency by over 90%. 展开更多
关键词 Phase-field model Finite difference method Fast Poisson solver(DC-T/DST) Explicit invariant energy quadratization Unconditional energy stability
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