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遗传性凝血因子XI缺陷症家系调查及输血
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作者 韩雅馨 任颖 +2 位作者 赵蓉 屈爱春 杨志刚 《中国实验血液学杂志》 北大核心 2025年第4期1161-1167,共7页
目的:对一例遗传性凝血因子XI(FXI)缺陷症患者进行家系调查,明确其可能的遗传学病因,并对先证者出血风险进行分析,提供输血方案。方法:收集家系样本,检测先证者及其家系成员相关凝血指标。对先证者进行全外显子组测序寻找基因突变,应用S... 目的:对一例遗传性凝血因子XI(FXI)缺陷症患者进行家系调查,明确其可能的遗传学病因,并对先证者出血风险进行分析,提供输血方案。方法:收集家系样本,检测先证者及其家系成员相关凝血指标。对先证者进行全外显子组测序寻找基因突变,应用Sanger测序对该家系进行验证。用生物信息学软件分析氨基酸变异位点的保守性,分析变异对蛋白质功能的影响。根据美国医学遗传学与基因组学会(ACMG)遗传变异分类标准及指南对变异位点致病性进行分析。运用血栓弹力图(TEG)检测该家系成员凝血功能,并评估先证者的输血方案和疗效。结果:先证者活化部分凝血活酶时间(APTT)明显延长至96.7 s,FXI活性(FXI:C)和FXI抗原(FXI:Ag)分别降至1.3%和1%,均极度减低;先证者父亲的FXI:C也明显低于正常值。TEG结果显示,先证者凝血功能减低,其余家系成员凝血功能正常。先证者F11基因存在c.738G>A(p.Trp246*)和c.1288G>A(p.Ala430Thr)复合杂合变异。先证者父亲携带c.1288G>A(p.Ala430Thr)杂合错义变异,先证者母亲、大女儿和小女儿携带c.738G>A(p.Trp246*)杂合无义变异。根据ACMG遗传变异分类标准及指南,c.738G>A(p.Trp246*)变异判定为致病性变异(PVS1+PS3_Moderate+PP4),c.1288G>A(p.Ala430Thr)变异判定为可能致病(PS3_Moderate+PM1+PM3_Strong+PP4)。p.Trp246和p.Ala430在不同物种中均高度保守。Swiss-Pdb Viewer软件分析表明,p.Ala430Thr变异导致FXI蛋白氢键数量发生改变,影响蛋白质功能。TEG体外评估确定输血方案,选择术前24 h输新鲜冰冻血浆600 ml预防出血,手术过程中及术后无明显出血。结论:F11基因的c.738G>A(p.Trp246*)杂合无义变异和c.1288G>A(p.Ala430Thr)杂合错义变异是该遗传性FXI缺陷症家系的致病原因。 展开更多
关键词 遗传性Fxi缺陷症 F11基因 血栓弹力图 基因变异 输血
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杜梨LRR-XI-a亚家族的鉴定及调控腐烂病抗性的成员筛选 被引量:1
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作者 蔡敏蕊 田玉珍 +2 位作者 孙娥 郑艳 左存武 《核农学报》 CAS CSCD 北大核心 2024年第8期1425-1433,共9页
为探究LRR-XI-a基因家族在杜梨免疫系统中的作用机制,基于GDR数据库的杜梨基因组数据鉴定了杜梨LRR-XI-a家族成员,经进化特征、基因重复事件和表达模式分析筛选了响应腐烂病信号的成员,并结合果实瞬时表达和抗性基因表达分析对部分成员... 为探究LRR-XI-a基因家族在杜梨免疫系统中的作用机制,基于GDR数据库的杜梨基因组数据鉴定了杜梨LRR-XI-a家族成员,经进化特征、基因重复事件和表达模式分析筛选了响应腐烂病信号的成员,并结合果实瞬时表达和抗性基因表达分析对部分成员的功能进行了初步分析。结果表明,杜梨LRR-XI-a基因家族包含91个成员,进化上可分为6个亚组。基因重复分析结果表明,杜梨中GroupⅠ成员数的迅速增加可能由串联复制(TD)和全基因组复制(WGD)共同导致,而GroupⅥ成员的增加仅由WGD所致。顺式作用元件分析结果表明,杜梨LRR-XI-a亚组Ⅱ和Ⅵ可能主要参与杜梨对非生物逆境信号的响应,而其余4个亚组同时参与对生物和非生物逆境信号的响应。表达分析结果表明,LRR-XI-4和LRR-XI-5在腐烂病侵染后呈不同程度的上调表达,其中LRR-XI-5上调表达量可达对照的586倍以上。果实瞬时表达分析结果表明,过表达LRR-XI-4和LRR-XI-5降低了梨果实对腐烂病的抗性,抑制了JA信号通路基因的表达,但激活了超敏反应响应基因的表达。综上,基因重复导致杜梨LRR-XI-a家族成员发生迅速增加;LRR-XI-a家族成员响应不同的生物胁迫和非生物胁迫;LRR-XI-4和LRR-XI-5通过激活超敏反应(HR)相关基因的表达负调控腐烂病抗性,可作为后期腐烂病抗性研究的候选基因。本研究结果为后续开展梨抗病机理研究和分子育种奠定了基础。 展开更多
关键词 杜梨 LRR-xi-a 基因家族 基因重复 腐烂病
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牛凝血因子XI基因15bp插入突变的分子检测及基因频率分析 被引量:1
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作者 李强 张毅 +7 位作者 王雅春 吴蒙 徐仙洲 张智军 孙东晓 俞英 张胜利 张沅 《畜牧兽医学报》 CAS CSCD 北大核心 2013年第8期1213-1218,共6页
牛凝血因子XI基因第9外显子15bp插入突变是近年在日本和牛中发现的一种遗传缺陷,导致凝血因子活性降低。为了分析该缺陷基因在我国牛群中的携带频率,本研究开发了能灵敏检测该突变的2种新方法,即毛细管电泳法和等位基因特异性扩增法,并... 牛凝血因子XI基因第9外显子15bp插入突变是近年在日本和牛中发现的一种遗传缺陷,导致凝血因子活性降低。为了分析该缺陷基因在我国牛群中的携带频率,本研究开发了能灵敏检测该突变的2种新方法,即毛细管电泳法和等位基因特异性扩增法,并检测了我国引进的和牛种公牛、1个含和牛血液的杂交育种群和商品群、4个国内地方品种(鲁西牛、延边牛、蒙古牛、复州牛)、2个培育品种(中国荷斯坦牛、新疆褐牛)和6个国外品种(西门塔尔、夏洛来、利木赞、安格斯、蒙贝利亚、挪威红牛)样品共452头份。结果显示,在和牛、含和牛血液的杂交育种群及商品群中突变基因频率分别为0.182、0.389和0.242,在延边牛中发现1头携带者,而在其余群体中均未检出,推测该突变可能只存在于东北亚和我国东北地区牛群中。今后我国在引进和牛用于杂交改良以及本地牛选育中需要对该突变进行分子检测和逐步淘汰,从而降低不利等位基因的频率。 展开更多
关键词 凝血因子xi 遗传缺陷 和牛 毛细管电泳 等位基因特异性扩增
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Xi-3米曲霉菌株的保藏与复壮
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作者 吕明霞 徐海燕 曹斌 《中国酿造》 CAS 北大核心 2005年第3期44-45,共2页
介绍了Xi-3米曲霉菌株的保藏与复壮的具体做法。采用麸皮保藏法可以使Xi-3米曲霉保藏18年之久且菌种优良性状不变;行之有效的复壮措施,提高了保藏菌株的优良性状和生产性能,为种质资源的可持续发展作出了贡献。
关键词 xi-3米曲霉 中性蛋白酶
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中国荷斯坦牛凝血因子XI缺陷症遗传分析 被引量:2
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作者 东天 谢岩 +5 位作者 孙东晓 张沅 张胜利 张毅 刘林 陈绍祜 《中国奶牛》 2011年第22期27-29,共3页
凝血因子XI缺陷症(Factor XI deficiency)是荷斯坦牛的一种常染色体单基因控制的隐性遗传缺陷。该病的遗传基础是由位于牛第27号染色体的凝血因子XI基因外显子12上发生的一段76bp序列插入。本研究采用PCR方法对我国13个主要公牛站的571... 凝血因子XI缺陷症(Factor XI deficiency)是荷斯坦牛的一种常染色体单基因控制的隐性遗传缺陷。该病的遗传基础是由位于牛第27号染色体的凝血因子XI基因外显子12上发生的一段76bp序列插入。本研究采用PCR方法对我国13个主要公牛站的571头荷斯坦公牛的凝血因子XI基因进行了全面检测,未发现隐性有害基因携带者和纯合个体。 展开更多
关键词 中国荷斯坦公牛 凝血因子xi缺陷症 分子诊断
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达芬奇Xi机器人在单侧腋窝入路免充气甲状腺手术中的临床应用分析 被引量:8
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作者 史荣亮 张婷婷 +10 位作者 王宇 倪兆娴 王慧 王玉龙 魏文俊 向俊 渠宁 卢忠武 范鹃 顾玮瑾 嵇庆海 《中国癌症杂志》 CAS CSCD 北大核心 2023年第11期1018-1025,共8页
背景和目的:2007年,Kang等第1次将机器人手术应用于甲状腺,之后机器人甲状腺手术在全球范围内开展。因安全性、肿瘤治疗的根治性和美容性不断得到验证,腋窝入路比例在国内正在快速增长。本研究通过对比分析使用达芬奇Xi机器人完成的95... 背景和目的:2007年,Kang等第1次将机器人手术应用于甲状腺,之后机器人甲状腺手术在全球范围内开展。因安全性、肿瘤治疗的根治性和美容性不断得到验证,腋窝入路比例在国内正在快速增长。本研究通过对比分析使用达芬奇Xi机器人完成的95例单侧腋窝入路免充气甲状腺手术与91例传统手术治疗cN0期甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)的临床疗效,探讨达芬奇Xi机器人单侧腋窝入路手术治疗PTMC的优势及临床应用价值。方法:回顾性分析2020年3月—2021年11月复旦大学附属肿瘤医院头颈外科收治的186例cN0期单侧单灶PTMC患者的临床数据,根据手术方式分为机器人组(95例)和开放组(91例),分析比较两组患者的一般临床资料、手术结果、术后并发症、切口满意度、学习曲线及手术费用等情况。结果:两组患者在性别、年龄、是否合并桥本甲状腺炎、肿瘤直径及病灶位置方面差异无统计学意义(P>0.05)。机器人组手术时间[(126.65±34.76)min]长于开放组[(60.99±21.12)min],在经历36例手术后手术时间可达稳定水平。手术费用[(47940.66±4404.30)元]高于开放组[(15807.73±2295.35)元]。在术中出血量[机器人组:(20.48±18.83)mL;开放组:(16.15±13.95)mL]、清扫淋巴结个数[机器人组:(2.61±2.77)枚;开放组:(2.97±2.20)枚]和检出阳性淋巴结个数[机器人组:(1.01±1.61)枚;开放组:(0.78±1.36)枚]方面差异无统计学意义(P>0.05)。机器人组术后暂时性声嘶(1.10%)低于开放组(2.20%),但差异无统计学意义(P>0.05)。机器人组术后切口满意度(非常满意87.4%,比较满意11.6%)高于开放组(非常满意71.4%,比较满意26.4%),差异有统计学意义(P<0.05)。结论:达芬奇Xi机器人单侧腋窝入路免充气甲状腺手术不仅具有良好的美容效果,较高的患者满意度,而且学习曲线短,术中出血量、淋巴结检测情况及术后并发症发生情况与传统手术相当。 展开更多
关键词 甲状腺微小乳头状癌 达芬奇xi机器人 传统开放手术 甲状腺切除术
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稻瘟病拮抗菌Xi-55菌株鉴定及其发酵条件 被引量:1
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作者 刘波微 彭化贤 +1 位作者 曹玉桃 席亚东 《中国生物防治》 CSCD 北大核心 2006年第S1期124-128,共5页
通过对采集样品中细菌的分离获得生防菌Xi-55,经纯化培养后观察形态特征和生理生化特征,经比较鉴定,确定生防菌Xi-55为枯草芽孢杆菌。通过田间试验测定,初步确定了枯草芽孢杆菌Xi-55菌株防治稻瘟病的效果为86%。对该菌株发酵条件进行了... 通过对采集样品中细菌的分离获得生防菌Xi-55,经纯化培养后观察形态特征和生理生化特征,经比较鉴定,确定生防菌Xi-55为枯草芽孢杆菌。通过田间试验测定,初步确定了枯草芽孢杆菌Xi-55菌株防治稻瘟病的效果为86%。对该菌株发酵条件进行了研究,确定出最佳发酵技术参数,为微生物农药的开发提供理论依据。 展开更多
关键词 稻瘟病 生防菌 发酵条件
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A Study of Xi Jinping Thought on Governing the Country Based on the Unity of “Party Spirit-People’s Nature”
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作者 Li Kai 《学术界》 CSSCI 北大核心 2019年第4期215-225,共11页
The unity of “party spirit-people’s nature” is the basic proposition of Xi Jinping’s governance.Deng Xiaoping summarized the experience and lessons in the early days of reform and opening up,and put forward the ba... The unity of “party spirit-people’s nature” is the basic proposition of Xi Jinping’s governance.Deng Xiaoping summarized the experience and lessons in the early days of reform and opening up,and put forward the basic line of the “leadership and unity” of the party in the early stage of socialism around “one center,two basic points”;Xi Jinping’s so-called “unification”,which is based on the the basic line of Deng Xiaoping’s initial stage of building a socialist country that is “rich,strong,democratic,civilized,harmonious and beautiful”,has further established the importance of “people as the center” and “party’s leadership”.Therefore,the “people-centered” and “the party’s overall leadership” are unified and become the basic idea of General Secretary Xi Jinping’s governance of the country.Xi Jinping has put forward the unity of “party spirit-people’s nature”,the “consistency” between governing the country and politics,and the “integration” between the people’s interests and the party’s leadership,thus forming “persistence”,“comprehensive”,“confidence”,“maintenance” and other assertions. 展开更多
关键词 the UNITY of party spirit-people's NATURE governing the COUNTRY xi Jinping THOUGHT
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The Scientific System of Xi Jinping Thought on Socialist Culture with Chinese Characteristics for a New Era
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作者 Ma Dekun 《学术界》 CSSCI 北大核心 2018年第10期248-260,共13页
Since the 18 th CPC National Congress,the Party Central Committee,with Comrade Xi Jinping as the core,has formed Xi Jinping Thought on Socialism with Chinese Characteristics( Xi's TSCC) for a New Era in the proces... Since the 18 th CPC National Congress,the Party Central Committee,with Comrade Xi Jinping as the core,has formed Xi Jinping Thought on Socialism with Chinese Characteristics( Xi's TSCC) for a New Era in the process of upholding and developing the great practice of Socialism with Chinese Characteristics( SCC). As an important part of Xi's TSCC for a new era, cultural thought takes the persistence of cultural confidence as its basic foundation,t he promotion of outstanding traditional culture as its important measure,the enhancement of cultural soft power as its strategic goal,t he cultivation &practice of core socialist values as its guide, and the improvement of clean government culture as its fundamental significance,t hus constituting a scientific system with complete structure, rich content and rigorous exposition. This important thought provides a powerful theoretical and practical guide to the work of building a socialist culture with Chinese characteristics in the new era. 展开更多
关键词 xi Jinping NEW ERA CULTURAL THOUGHT SCIENTIFIC system
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Dialectical Unity of Xi Jinping’s Thought on Diplomacy
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作者 Zhao Yongchen 《国际问题研究》 CSSCI 北大核心 2018年第3期143-164,共22页
关键词 DIALECTICAL UNITY of xi Jinping's THOUGHT DIPLOMACY
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Xi Jinping’s Analysis of “A Common Future for Humanity”:Its Relation to Marx’s Das Kapital
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作者 John Ross 《学术界》 CSSCI 北大核心 2019年第4期185-189,共5页
President Xi Jinping’s analysis of “a common future for humanity” is one of the most important and original features of China’s foreign policy and of “Xi Jinping’s Thought on Socialism with Chinese Characteristi... President Xi Jinping’s analysis of “a common future for humanity” is one of the most important and original features of China’s foreign policy and of “Xi Jinping’s Thought on Socialism with Chinese Characteristics for a New Era”.This concept is comprehensible not only in classical Chinese but in Western philosophical thought.Therefore,it is a creative development of Marxism whose accurate relation to economic reality,provides an exceptionally firm basis for China’s foreign policy and that of other countries. 展开更多
关键词 xi Jinping a COMMON FUTURE for HUMANITY Marx CLASSICAL Chinese THOUGHT Western THOUGHT
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On the Four Dimensions of Xi Jinping’s Ecological View
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作者 Zhang Fengfan Li Dongsong 《学术界》 CSSCI 北大核心 2019年第7期196-207,共12页
Since the 18th CPC National Congress,the Party Central Committee with General Secretary Xi Jinping as the core has been committed to the construction of ecological civilization,scientific and in-depth understanding of... Since the 18th CPC National Congress,the Party Central Committee with General Secretary Xi Jinping as the core has been committed to the construction of ecological civilization,scientific and in-depth understanding of the law of human and economic and social development,creatively proposed a series of new strategies,and has formed a comprehensive and systematic Xi Jinping’s ecological view.The basic connotation is:adhering to the ecological economic view of green development,focusing on the domestic and international ecological political view,constructing an ecological cultural view in harmony between man and nature,and an ecological social view unifying environmental protection and people’s happinesses.Xi Jinping’s ecological view is the inheritance and development of Marxist ecological theory,the enrichment and perfection of theoretical system of socialism with Chinese characteristics (SCC),the new understanding of the laws governing the development of human civilization,the important content for the Chinese dream,and an action to build a beautiful China,thus contributing Chinese wisdom to global ecological governance. 展开更多
关键词 xi Jinping ECOLOGICAL VIEW FOUR DIMENSIONS
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The Organic Unity of Purposiveness and Regularity:Dialectical Thinking on President Xi Jinping’s Economic Work
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作者 ZHANG Liang 《河海大学学报(哲学社会科学版)》 CSSCI 2016年第1期89-92,共4页
President Xi Jinping has constantly taken theeconomic development as the central work from theperspective of historical materialism and dialecticalmaterialism.He corresponds to the law of economicdevelopment,and accur... President Xi Jinping has constantly taken theeconomic development as the central work from theperspective of historical materialism and dialecticalmaterialism.He corresponds to the law of economicdevelopment,and accurately masters the important logicrelations between economy and politics,government andmarket.Meanwhile,he proposes that China should useoverall planning to deal with the difficulty of urban-ruralintegration so as to thoroughly solve the three agriculture-related issues.Then,it is possible to achieve the organicunity of purposiveness and regularity. 展开更多
关键词 xi Jinping ECONOMIC work purposiveness REGULARITY urban?rural integration
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The Historical Leap of Marxism of the New Era in China
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作者 YUAN Fang-jiang 《学习与探索》 CSSCI 北大核心 2017年第11期191-192,共2页
At the beginning ol the report made by general secretary Xi Jinping on behalf ol the eighteenth Cen-tral Committee ol the party to the 19th CPC National Congress,the significant political judgment was raised-Socialism... At the beginning ol the report made by general secretary Xi Jinping on behalf ol the eighteenth Cen-tral Committee ol the party to the 19th CPC National Congress,the significant political judgment was raised-Socialism with Chinese characteristics has entered a new era.This major political judgment has a epoch-mak-ing significance,lor it not only determines the new historical position ol China’s development,but also inau-gurates a new historical process in the construction ol socialism with Chinese characteristics.Entering the new era means that the Communist Party ol China has realized the third great revolution,and the Chinese nation has brought about a great leap lrom standing up,becoming well-oll to getting stronger;means that with great vitality,the scientilic socialism in China in twenty-lirst Century has been served as a powerlul support and im-petus to the cause ol socialism in the world;means that the socialist road,theory,system and culture with Chinese characteristics have been developing continuously,and made a great contribution to solve the problem ol human beings by Chinese wisdom and China program.The most important political,theoretical,historical and practical signilicance ol socialism with Chinese characteristics in the new era relies on the lact that the Ma-rx doctrine has achieved a new historical leap in China. 展开更多
关键词 the 19th CPC National Congress xi Jinping the New Era Socialism with Chinese Characteristics
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Journal of Xi'an Jiaotong University (Medical Sciences) Guide to Authors
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《西安交通大学学报(医学版)》 CAS CSCD 北大核心 2005年第2期F003-F004,共2页
关键词 Guide to Authors Journal of xi’an Jiaotong University
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The First IEEE International Symposium On Industrial Electronics Held in Xi'an
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作者 CoChairman, Technical Program Committee The First IEEE International Symposium on Industrial Electronics June 7,1992 《西北工业大学学报》 EI CAS CSCD 北大核心 1992年第3期293-,共1页
The First IEEE International symposium on Industrial Electronics (ISIE) was held at Holiday Inn,xian, P.R.China on May 25-29,1992. The symposium was jointly sponsored by the IEEE Industrial Electronics Society(IES), t... The First IEEE International symposium on Industrial Electronics (ISIE) was held at Holiday Inn,xian, P.R.China on May 25-29,1992. The symposium was jointly sponsored by the IEEE Industrial Electronics Society(IES), the IEEE Beijing Section, the Society of Instrument and Control Engineers((?)pan), and the Shaanxi Provincial science and Technology Commission, in cooperation with Northwestern Polytechnieal University(NPU), Xian Jiaotong University and Xidian University. 展开更多
关键词 IEEE The First IEEE International Symposium On Industrial Electronics Held in xi’an
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On the Global Significance of XI Jin-ping Thought on Socialism with Chinese Characteristics for a New Era
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作者 CHEN Jin-long 《华东师范大学学报(哲学社会科学版)》 CSSCI 北大核心 2018年第3期173-177,共5页
XI Jin-ping thought on socialism with Chinese characteristics for a new era contains Chinese wisdom for the development of socialism in the world,Chinese experience of realizing modernization in adeveloping country,an... XI Jin-ping thought on socialism with Chinese characteristics for a new era contains Chinese wisdom for the development of socialism in the world,Chinese experience of realizing modernization in adeveloping country,and Chinese solution to the global governing.It clarifies the theoretical puzzlement of"theend of history","the clash of civilizations"and"Western centrism",so that it plays an important role inhuman intellectual history.Therefore,one should adopt an international vision and a global perspective tounderstand and evaluate the theoretical significance and practical value of XI Jin-ping thought on socialism with Chinese characteristics for a new era. 展开更多
关键词 xi Jin-ping thought on socialism with Chinese characteristics for a new era Chinese wisdom global significance
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How to Develop into An International Metropolis in the Context of the Silk Road Economic Belt —— A Case Study of Xi'an 被引量:1
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作者 Chen Weifeng Qian Xiaoping 《学术界》 CSSCI 北大核心 2015年第4期318-322,共5页
For Xi'an,the central city of the Silk Road Economic Belt,it is both the theoretical and practical problem to develop into an international metropolis,so how to develop into an international metropolis becomes the... For Xi'an,the central city of the Silk Road Economic Belt,it is both the theoretical and practical problem to develop into an international metropolis,so how to develop into an international metropolis becomes the research focus. This paper firstly introduces the necessity,the current situation and the evaluation index system of the construction of the city Xi'an in the context of the Silk Road Economic Belt; then it analyzes the econom ic developm ent of the three old districts,the three new districts,the three suburban districts and the four counties; and finally it puts forward the development path for Xi'an in the context of the Silk Road Economic Belt — the development pattern of "five districts,one international harbor area and two bases""nine-grid-pattern "economic development and the function-oriented coordinated development of the regional economy. 展开更多
关键词 国际化大都市 丝绸之路 经济带 西安 语境 评价指标体系 中心城市 经济发展
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An Outline of Zhu Xi's Dual Personality
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作者 Fu Changzhen 《学术界》 CSSCI 北大核心 2013年第5期241-248,共8页
Zhu Xi is a comprehensive synthesizer of Neo - Confucianism that developed during early Song Dynasty. Follow ing the meticulous spiritual direction of Cheng Yi,he has expanded the moral rationalism in the Song dynasty... Zhu Xi is a comprehensive synthesizer of Neo - Confucianism that developed during early Song Dynasty. Follow ing the meticulous spiritual direction of Cheng Yi,he has expanded the moral rationalism in the Song dynasty to the utmost. His strong group orientation leads him to attaching priority to normative rules and operative convenience,but his individual orientation leads him to seeking for the unrestrained poetic w ay of life. His pursuits of both the moral ideal of rationalism and the poetic life of romanticism result in his dual personality. He devoted all his life to the efforts to solve the conflict and tension betw een his dual pursuits,w hich provide an important clue for the profound understanding of the complexity of his philosophy. 展开更多
关键词 朱熹 人格 理性主义 发达国家 浪漫主义 宋代 道德 取向
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基于SAM2多任务学习的山区地块模糊边界提取 被引量:1
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作者 黄启厅 凌玉荣 +6 位作者 谢国雪 杨绍锷 杨颖频 李海亮 梁存穗 何新洁 谢意 《南方农业学报》 北大核心 2025年第1期18-28,F0002,共12页
【目的】构建多任务模糊边界提取深度学习模型,解决模糊边界难提取及伪边界难消除的问题,为地块破碎地区的地块边界提取提供参考依据。【方法】以广西河池市宜州区为研究区,通过解译典型山区破碎遥感影像,建立模糊边界提取数据集,引入S... 【目的】构建多任务模糊边界提取深度学习模型,解决模糊边界难提取及伪边界难消除的问题,为地块破碎地区的地块边界提取提供参考依据。【方法】以广西河池市宜州区为研究区,通过解译典型山区破碎遥感影像,建立模糊边界提取数据集,引入SAM2视觉大模型及采用适配器Adapter微调优化其编码器,设计地块属性提取辅助任务,构建多任务模糊边界提取深度学习模型SAM2Xi,并通过对比试验证实该模型在山区地块破碎环境下的模糊边界提取效果。【结果】SAM2Xi模型在全局最佳阈值(ODS)和单图最佳阈值(OIS)上表现最佳,分别为0.663和0.672,显示出最高的边缘检测精度和适应性,但50%精度召回率(R50)略低于DexiNed模型。SAM2Xi模型结合语义信息与边缘特征,增强了模糊边界识别能力,在复杂场景下表现尤为出色;SAM2Xi模型在低对比度和复杂背景下仍然保持高精度,模糊边界区域的细节保留、连贯性和噪声抑制均优于其他模型;此外,SAM2Xi模型在伪边界清除任务中表现最佳,其先进特征提取和优化机制几乎完全消除了伪边界干扰,在各类场景下保持高精度边缘检测,具有更高的鲁棒性和准确性。SAM2Xi模型能成功提取研究区的地块信息(地块图斑数1587597个,总面积145696.646 ha),且提取的地块分布与实际情况高度吻合,具体表现为:(1)在大片耕地范围内可准确划分各地块;(2)可提取建筑物中的零星耕地或园地;(3)可提取林地中能被单独分割的地块(人工林),但自然林基本不会被误识。【结论】基于SAM2多任务学习构建的SAM2Xi模型实现了模糊边界识别与伪边界清除的双重突破,在复杂地形适应性、边界连贯性保持及噪声抑制方面具有明显优势,为我国西南山区复杂地形下地块边界提取及山区农业资源精准管理提供了技术支撑。 展开更多
关键词 地块边界提取 SAM2 多任务学习 遥感影像 SAM2xi模型
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