Based on salient visual regions for mobile robot navigation in unknown environments, a new place recognition system was presented. The system uses monocular camera to acquire omni-directional images of the environment...Based on salient visual regions for mobile robot navigation in unknown environments, a new place recognition system was presented. The system uses monocular camera to acquire omni-directional images of the environment where the robot locates. Salient local regions are detected from these images using center-surround difference method, which computes opponencies of color and texture among multi-scale image spaces. And then they are organized using hidden Markov model (HMM) to form the vertex of topological map. So localization, that is place recognition in our system, can be converted to evaluation of HMM. Experimental results show that the saliency detection is immune to the changes of scale, 2D rotation and viewpoint etc. The created topological map has smaller size and a higher ratio of recognition is obtained.展开更多
OBJECTIVE To investigate the effects of heat shock protein 70(Hsp70)in the development as well as expression of morphine induced conditioned place preference(CPP)in rats using Hsp70 inhibitors.METHODS The unbi⁃ased pr...OBJECTIVE To investigate the effects of heat shock protein 70(Hsp70)in the development as well as expression of morphine induced conditioned place preference(CPP)in rats using Hsp70 inhibitors.METHODS The unbi⁃ased procedures of CPP lasted for 7 d and included three phases:preconditioning(D1-D3),conditioning(D4-D6,6 sessions)and test(D7).Here,morphine 5 mg·kg-1 injected in a subcuta⁃neous(sc)manner can induce significant place preference.Inhibitors of Hsp70 were injected into the right lateral ventricle during either the condi⁃tioning phase or the test phase separately.Fur⁃thermore,the expression of Hsp70 in certain areas of the mesocorticolimbic system was also studied following the intervention of N-formyl-3,4-methylenedioxybenzylidine-γ-butyrolactam(KNK437),a transcriptional inhibitor of Hsp70.RESULTS Pifithrin-μ(PES),a selective functional inhibitor acting on the substrate binding domain(SBD)of Hsp70,dose-dependently suppressed both the acquisition and expression of morphine-induced CPP.Similar function was observed after the intracerebroventricular injection(icv)of KNK437.The other functional inhibitor methy⁃lene blue,targeting the nucleotide-binding area,showed a significant tendency of inhibitory phar⁃macological effect on the expressional and devel⁃opment phases of morphine-induced CPP.Following the interventions of KNK437,we found that the level of Hsp70 was significantly decreased in the NAcs both in the acquisition and expres⁃sion of morphine induced CPP.CONCLUSION Hsp70 in NAcs plays a critical role in mediating the psychological dependence induced by morphine.展开更多
The compositions, technical principles and construction equipments of a new piling method used for ground improvement plastic tube cast-in-place concrete pile were introduced. The results from static load tests on sin...The compositions, technical principles and construction equipments of a new piling method used for ground improvement plastic tube cast-in-place concrete pile were introduced. The results from static load tests on single piles with different forms of pile shoes and on their composite foundations were analyzed. The distribution patterns of axial force, shaft friction and toe resistance were studied based on the measurements taken from buried strain gauges. From the point of engineering application, the pile has merits in convenient quality control, high bearing capacity and reliable quality, showing higher reasonability, advancement and suitability than other ground improvement methods. The pile can be adopted properly to take place of ordinary ground improvement method, achieving greater economical and social benefits.展开更多
Australian women writers have taken active roles in the literary field under the influence of the Feminist Movement around the world since the latter half of the 20 th century. Kate Grenville rose to fame for her earl...Australian women writers have taken active roles in the literary field under the influence of the Feminist Movement around the world since the latter half of the 20 th century. Kate Grenville rose to fame for her early novel Lillian's Story representative of radical feminism. Ten years later in 1994,on reflection,she wrote Dark Places as a complementary work in the point viewof the very man,father and rapist,Albion,who appeared in the earlier novel. By reading the dark places,the inner heart of a patriarchal man and the undercurrent of misogyny in Albion's social world,the author sympathizes with and seeks to understand the inner nature of men,indicating her change in vision from initial radicalism to post- feminism which advocates understanding and harmony between men and women.展开更多
基金Projects(60234030 ,60404021) supported by the National Natural Science Foundation of China
文摘Based on salient visual regions for mobile robot navigation in unknown environments, a new place recognition system was presented. The system uses monocular camera to acquire omni-directional images of the environment where the robot locates. Salient local regions are detected from these images using center-surround difference method, which computes opponencies of color and texture among multi-scale image spaces. And then they are organized using hidden Markov model (HMM) to form the vertex of topological map. So localization, that is place recognition in our system, can be converted to evaluation of HMM. Experimental results show that the saliency detection is immune to the changes of scale, 2D rotation and viewpoint etc. The created topological map has smaller size and a higher ratio of recognition is obtained.
基金National Natural Science Foundation of China(81773705)。
文摘OBJECTIVE To investigate the effects of heat shock protein 70(Hsp70)in the development as well as expression of morphine induced conditioned place preference(CPP)in rats using Hsp70 inhibitors.METHODS The unbi⁃ased procedures of CPP lasted for 7 d and included three phases:preconditioning(D1-D3),conditioning(D4-D6,6 sessions)and test(D7).Here,morphine 5 mg·kg-1 injected in a subcuta⁃neous(sc)manner can induce significant place preference.Inhibitors of Hsp70 were injected into the right lateral ventricle during either the condi⁃tioning phase or the test phase separately.Fur⁃thermore,the expression of Hsp70 in certain areas of the mesocorticolimbic system was also studied following the intervention of N-formyl-3,4-methylenedioxybenzylidine-γ-butyrolactam(KNK437),a transcriptional inhibitor of Hsp70.RESULTS Pifithrin-μ(PES),a selective functional inhibitor acting on the substrate binding domain(SBD)of Hsp70,dose-dependently suppressed both the acquisition and expression of morphine-induced CPP.Similar function was observed after the intracerebroventricular injection(icv)of KNK437.The other functional inhibitor methy⁃lene blue,targeting the nucleotide-binding area,showed a significant tendency of inhibitory phar⁃macological effect on the expressional and devel⁃opment phases of morphine-induced CPP.Following the interventions of KNK437,we found that the level of Hsp70 was significantly decreased in the NAcs both in the acquisition and expres⁃sion of morphine induced CPP.CONCLUSION Hsp70 in NAcs plays a critical role in mediating the psychological dependence induced by morphine.
基金Project (2007H03) supported by Communications Department of Zhejiang Province
文摘The compositions, technical principles and construction equipments of a new piling method used for ground improvement plastic tube cast-in-place concrete pile were introduced. The results from static load tests on single piles with different forms of pile shoes and on their composite foundations were analyzed. The distribution patterns of axial force, shaft friction and toe resistance were studied based on the measurements taken from buried strain gauges. From the point of engineering application, the pile has merits in convenient quality control, high bearing capacity and reliable quality, showing higher reasonability, advancement and suitability than other ground improvement methods. The pile can be adopted properly to take place of ordinary ground improvement method, achieving greater economical and social benefits.
基金Humanities and Social Sciences Research Planning Fund Key Project of Anhui Provinceunder Grant No.:SK2014A364namely“The Self in a Postmodernist Context:A Critical Study of Kate Grenville’s Fiction”
文摘Australian women writers have taken active roles in the literary field under the influence of the Feminist Movement around the world since the latter half of the 20 th century. Kate Grenville rose to fame for her early novel Lillian's Story representative of radical feminism. Ten years later in 1994,on reflection,she wrote Dark Places as a complementary work in the point viewof the very man,father and rapist,Albion,who appeared in the earlier novel. By reading the dark places,the inner heart of a patriarchal man and the undercurrent of misogyny in Albion's social world,the author sympathizes with and seeks to understand the inner nature of men,indicating her change in vision from initial radicalism to post- feminism which advocates understanding and harmony between men and women.
