Background Cotton crop is infested by numerous arthropod pests from sowing to harvesting,causing substantial direct and indirect yield losses.Knowledge of seasonal population trends and the relative occurrence of pest...Background Cotton crop is infested by numerous arthropod pests from sowing to harvesting,causing substantial direct and indirect yield losses.Knowledge of seasonal population trends and the relative occurrence of pests and their natural enemies is required to minimize the pest population and yield losses.In the current study,analysis of the seasonal population trend of pests and natural enemies and their relative occurrence on cultivars of three cotton species in Central India has been carried out.Results A higher number and diversity of sucking pests were observed during the vegetative cotton growth stage(60 days after sowing),declining as the crop matured.With the exception of cotton jassid(Amrasca biguttula biguttula Ishida),which caused significant crop damage mainly from August to September;populations of other sucking insects seldom reached economic threshold levels(ETL)throughout the studied period.The bollworm complex populations were minimal,except for the pink bollworm(Pectinophora gossypiella Saunders),which re-emerged as a menace to cotton crops during the cotton cropping season 2017–2018 due to resistance development against Bt-cotton.A reasonably good number of predatory arthropods,including coccinellids,lacewings,and spiders,were found actively preying on the arthropod pest complex of the cotton crop during the early vegetative growth stage.Linear regression indicates a significant relationship between green boll infestations and pink bollworm moths in pheromone traps.Multiple linear regression analyse showed mean weekly weather at one-or two-week lag periods had a significant impact on sucking pest population(cotton aphid,cotton jassid,cotton whitefly,and onion thrips)fluctuation.Gossypium hirsutum cultivars RCH 2 and DCH 32,and G.barbadense cultivar Suvin were found susceptible to cotton jassid and onion thrips.Phule Dhanvantary,an G.arboreum cotton cultivar,demonstrated the highest tolerance among all evaluated cultivars against all sucking pests.Conclusion These findings have important implications for pest management in cotton crops.Susceptible cultivars warrant more attention for plant protection measures,making them more input-intensive.The choice of appropriate cultivars can help minimize input costs,thereby increasing net returns for cotton farmers.展开更多
Spores and pollen,as ubiquitous organisms found in nature,possess a remarkable core-shell structure and intricate surface morphology.These tiny particles are notable for their dimensional uniformity,sustainable utiliz...Spores and pollen,as ubiquitous organisms found in nature,possess a remarkable core-shell structure and intricate surface morphology.These tiny particles are notable for their dimensional uniformity,sustainable utilization,environmental friendliness,porosity,amphiphilicity,and strong adhesive properties.In addition,they display excellent biocompatibility and biodegradability,which significantly enhances the stability and targeting of drugs within the body.Spores and pollen can be extracted using methods such as acidic solutions,alkaline solutions,or enzyme treatments to obtain sporopollenin,which is an extremely resilient and chemically inert complex biopolymer.The sporopollenin extracted through this process removes the original bioactive substances,such as cell nuclei,enzymes,and DNA,providing greater drug loading capacity and containing no potential allergens or immunogens,thus further enhancing its drug loading capacity and improving safety in therapeutic applications.Due to these beneficial attributes,spores,pollen and sporopollenin have gained widespread use in a variety of drug delivery systems,such as targeted delivery,sustained drug delivery,toxicity mitigation,flavor masking,vaccine delivery,delivery of labile substances,and other applications.This review introduces the types of natural spores and pollen commonly used in drug delivery systems,including their main components,common effects,and uses in drug delivery systems,and so on.It subsequently summarizes novel optimization methods in their processing,such as physical treatment,surface modification,and chemical modification,which enable higher drug loading efficiency,stability,and targeting,among other benefits.Additionally,this paper reviews the research progress and applications of natural spores,pollen,and sporopollenin in drug delivery systems,while also touching on some innovative research content,such as novel nanomotor microcarriers developed based on pollen.Based on these research findings,we further elaborate on the advantages of spores,pollen,and sporopollenin in drug delivery systems.For example,they have high stability and drug loading capacity,good adhesion,excellent targeting,and are easy to modify functionally.Currently,they show promising prospects in the fields of targeted drug delivery,sustained-release drug delivery,as well as the delivery of drugs that are effective but slightly toxic,and are often used in research on the treatment of diseases such as cancer and inflammation.We have also highlighted the challenges they face in various applications and identified some issues that need to be addressed,including difficulties in largescale production,the need to improve extraction and purification processes,and the existence of a low but still noteworthy risk of allergies,in order to fully leverage their potential in drug delivery applications.According to current research,although spores,pollen,and sporopollenin face some unresolved issues in clinical drug delivery,they still have great potential overall and are expected to become a new generation of green drug delivery platforms.In the future,further research into their unique physical and chemical properties and structural characteristics will help develop more efficient and stable drug delivery systems to meet diverse treatment needs.We believe that continued exploration of natural spores,pollen,and sporopollenin will drive this emerging field to achieve continuous breakthroughs and progress,ultimately making an important contribution to the cause of human health.展开更多
Research on dual-fuel(DF)engines has become increasingly important as engine manufacturers seek to reduce carbon dioxide emissions.There are significant advantages of using diesel pilot-ignited natural gas engines as ...Research on dual-fuel(DF)engines has become increasingly important as engine manufacturers seek to reduce carbon dioxide emissions.There are significant advantages of using diesel pilot-ignited natural gas engines as DF engines.However,different combustion modes exist due to variations in the formation of the mixture.This research used a simulation model and numerical simulations to explore the combustion characteristics of high-pressure direct injection(HPDI),partially premixed compression ignition(PPCI),and double pilot injection premixed compression ignition(DPPCI)combustion modes under a low-medium load.The results revealed that the DPPCI combustion mode provides higher gross indicated thermal efficiency and more acceptable total hydrocarbon(THC)emission levels than the other modes.Due to its relatively good performance,an experimental study was conducted on the DPPCI mode engine to evaluate the impact of the diesel dual-injection strategy on the combustion process.In the DPPCI mode,a delay in the second pilot ignition injection time increased THC emissions(a maximum value of 4.27g/(kW·h)),decreased the emission of nitrogen oxides(a maximum value of 7.64 g/(kW·h)),increased and then subsequently decreased the gross indicated thermal efficiency values,which reached 50.4%under low-medium loads.展开更多
Interest in the possibility of storing and transporting natural gas in the form of clathrate hydrates has been increasing in recent years, particularly in some gas-importing and exporting countries.The technologies ne...Interest in the possibility of storing and transporting natural gas in the form of clathrate hydrates has been increasing in recent years, particularly in some gas-importing and exporting countries.The technologies necessary for realizing this possibility may be classified into those relevant to the four serial processes (a) the formation of a hydrate, (b) the processing (dewatering, pelletizing, etc. ) of the formed hydrate, (c) the storage and transportation of the processed hydrate, and (d) the regasification (dissociation) of the hydrate. The technological development of any of these processes is still at an early stage. For hydrate formation, for example, various rival operations have been proposed. However,many of them have never been subjected to actual tests for practical use. More efforts are required for examining the different hydrate-formation technologies and for rating them by comparison. The general design of the processing of the formed hydrate inevitably depends on both the hydrate-formation process and the storage/transportation process, hence it has a wide variability. The major uncertainty in the storage-process design lies in the as-yet unclarified utility of the "self-preservation" effect of the naturalgas hydrates. The process design as well as the relevant cost evaluation should strongly depend on whether the hydrates are well preserved at atmospheric pressure in large-scale storage facilities. The regasification process has been studied less extensively than the former processes. The state of the art of the technological development in each of the serial processes is reviewed, placing emphasis on the hydrate formation process.展开更多
Non-pneumatic tire appears to have advantages over traditional pneumatic tire in terms of flat proof and maintenance free.A mechanical elastic wheel(MEW) with a non-pneumatic elastic outer ring which functions as air ...Non-pneumatic tire appears to have advantages over traditional pneumatic tire in terms of flat proof and maintenance free.A mechanical elastic wheel(MEW) with a non-pneumatic elastic outer ring which functions as air of pneumatic tire was presented.The structure of MEW was non-inflatable integrated configuration and the effect of hinges was accounted for only in tension. To establish finite element model of MEW, various nonlinear factors, such as geometrical nonlinearity, material nonlinearity and contact nonlinearity, were considered. Load characteristic test was conducted by tyre dynamic test-bed to obtain force-deflection curve. And the finite element model was validated through load characteristic test. Natural dynamic characteristics of the MEW and its influencing factors were investigated based on the finite element model. Simulation results show that the finite element model closely matched experimental wheel. The results also show that natural frequency is related to ground constraints, material properties, loads and torques. Influencing factors as above obviously affect the amplitude of mode of vibration, but have little effect on mode of vibration shape. The results can provide guidance for experiment research, structural optimization of MEW.展开更多
Natural gas hydrates are a kind of nonpolluting and high quality energy resources for future, the reserves of which are about twice of the carbon of the current fossil energy (petroleum, natural gas and coal) on the e...Natural gas hydrates are a kind of nonpolluting and high quality energy resources for future, the reserves of which are about twice of the carbon of the current fossil energy (petroleum, natural gas and coal) on the earth. And it will be the most important energy for the 21st century. The energy balance and numerical simulation are applied to study the schemes of the natural gas hydrates production in this paper,and it is considered that both depressurization and thermal stimulation are effective methods for exploiting natural gas hydrates, and that the gas production of the thermal stimulation is higher than that of the depressurization. But thermal stimulation is non-economic because it requires large amounts of energy.Therefore the combination of the two methods is a preferable method for the current development of the natural gas hydrates. The main factors which influence the production of natural gas hydrates are: the temperature of injected water, the injection rate, the initial saturation of the hydrates and the initial temperature of the reservoir which is the most important factor.展开更多
The kinetics of the thermal decomposition for a naturally ageing ammonium perchlorate(AP) and hydroxyl-terminated-polybutadiene(HTPB) base bleed composite propellant were investigated using a differential scanning cal...The kinetics of the thermal decomposition for a naturally ageing ammonium perchlorate(AP) and hydroxyl-terminated-polybutadiene(HTPB) base bleed composite propellant were investigated using a differential scanning calorimetry(DSC). The naturally ageing AP/HTPB base bleed propellant samples have been stored in a sealed plastic bag at room temperature(5-25 ℃) for more than 20 years. The experimental DSC results were obtained by placing samples(each about 1.5 mg) in a sealed pan under non-isothermal condition under different heating rates, 5.0, 10.0, 15.0, 20.0 and 30.0 ℃·min^(-1). The activation energy and pre-exponential factor were estimated based on the relationship between the exothermic peak temperature and the heating rate by Ozawa and Kissinger methods, respectively. The decomposition kinetic parameters is lower the values under laboratorial aging condition.展开更多
The paper presents the investigation of the effect of alkaline treatment of sodium hydroxide(NaOH) on physical and dynamic mechanical analysis(DMA) viscoelastic properties of kenaf fibre filled natural rubber(NR)/ther...The paper presents the investigation of the effect of alkaline treatment of sodium hydroxide(NaOH) on physical and dynamic mechanical analysis(DMA) viscoelastic properties of kenaf fibre filled natural rubber(NR)/thermoplastic polyurethane(TPU) composites.The treated kenaf fiber,NR and TPU were weighed and proportioned according to the required compositions and were blended using hot mixed Brabender machine.The polymer composites were then fabricated using the hot press to form a sample board.The sample was cut and prepared and water absorption,density,thickness swelling and DMA tests were performed.As far as physical properties are concerned,composites with the highest NR amount of shows the best results,which indicates good fiber bonding adhesion.The polymer composites with the highest amount of TPU shows the highest damping properties at high temperature.展开更多
The effect of diluted solution's magnetization on induction time and growth period of natural gas hydrate (NGH) has been investigated in quiescent reaction system at pressure of 4. 5 MPa and temperature of 274 K w...The effect of diluted solution's magnetization on induction time and growth period of natural gas hydrate (NGH) has been investigated in quiescent reaction system at pressure of 4. 5 MPa and temperature of 274 K with SDS as surfactant, by using volume fixed and pressure falling method. Experimental results show that magnetization will have effect on the induction time of NGH. After magnetization with magnetic field intensity of 0.33 T, the induction time of NGH has been reduced to 47 min (average) from 99 min (average) in which there is no magnetization. On the other hand, the induction time has been prolonged after magnetization of the diluted solution with magnetic field intensity of 0.05 T, 0. 11 T, 0.22 T, 0.44T. Especially with magnetic field intensity of 0.11 T, the induction time had even been prolonged to 431min (average). The effect of magnetization on the growth period of NGH has not been found at the experimental condition.展开更多
Natural convection heat transfer from annular finned tubes was studied numerically. Effects of fin spacing, temperature difference and tube diameter on flow pathlines and local heat transfer were also studied. It was ...Natural convection heat transfer from annular finned tubes was studied numerically. Effects of fin spacing, temperature difference and tube diameter on flow pathlines and local heat transfer were also studied. It was shown that pathlines remain mostly circular for different geometries. Moreover, the contributions of fin periphery, fin side and bare tube to heat transfer were specified. It was shown that the heat transfer per unit area of fin periphery can be several times that of other parts. Moreover, in higher finspacing, the heat transfer from the bare tube can be more important than fin sides.展开更多
The processes involved in the major steps of successful revegetation of bauxite residues are examined.The first phase is the natural physical,chemical and microbial ripening of the profile.This involves allowing the p...The processes involved in the major steps of successful revegetation of bauxite residues are examined.The first phase is the natural physical,chemical and microbial ripening of the profile.This involves allowing the profile to drain,dry,shrink and crack to depth,leaching of soluble salts,alkalinity and Na down out of the surface layers,acidification by direct carbonation and natural seeding of tolerant vegetation with an accumulation of organic matter near the surface and an attendant development of an active microbial community.Following ripening,the surface layer can be tilled and gypsum and organic matter(e.g.manures,composts,biosolids)incorporated.These amendments result in a further decrease in pH,increase in Ca and other exchangeable cations,increased leaching of Na(with a reduction in exchangeable Na and ESP),improved physical properties,particularly aggregation,and a large increase in microbial activity.Other important considerations include the choice of suitable plant species tolerant to salinity/sodicity and local environmental conditions and the addition of balanced fertilizer applications.展开更多
Energy consumption of block-cutting machines represents a major cost item in the processing of travertines and other natural stones. Therefore, determining the optimum sawing conditions for a particular stone is of ma...Energy consumption of block-cutting machines represents a major cost item in the processing of travertines and other natural stones. Therefore, determining the optimum sawing conditions for a particular stone is of major importance in the natural stone-processing industry. An experimental study was carried out utilizing a fully instrumented block-cutter to investigate the sawing performances of five different types of travertine blocks during cutting with a circular diamond saw. The sawing tests were performed in the down-cutting mode. Performance measurements were determined by measuring the cutting speed and energy consumption. Then, specific energy was determined. The one main cutting parameter, cutting speed, was varied in the investigation of optimum cutting performance. Furthermore, some physico-mechanical properties of file travertine blocks were determined in the laboratory. As a result, it is found that the energy consumption （specific energy） of block cutting machines is highly affected by cutting speed. It is determined that specific energy value usually decreases when cutting speed increases. When the cutting speed is higher than the determined value, the diamond saw can become stuck in the travertine block; this situation can be a problem for the block-cutting machine. As a result, the optimum cutting speed obtained for the travertine mines examined is approximately 1.5-2.0 m/min.展开更多
Natural minerals receive growing attention as inexpensive, green, and efficient catalysts for degradation of organic pollutants. Mechanical activation of natural chalcopyrite was conducted for improving the catalytic ...Natural minerals receive growing attention as inexpensive, green, and efficient catalysts for degradation of organic pollutants. Mechanical activation of natural chalcopyrite was conducted for improving the catalytic performance.Tetracycline degradation was evaluated in the presence of hydrogen peroxide and mechanically activated chalcopyrite.Tetracycline degradation at 100 min is 55.52%(Chp10), 68.97%(Chp30), 77.79%(Chp60), and 86.43%(Chp120),respectively, and the rate constant of pseudo-first-order kinetics is 0.0079, 0.0109, 0.0137 and 0.0192 min^(-1), respectively.Chalcopyrite samples were examined by multiple characterizations. Mechanical activation of natural chalcopyrite induces the decline of particle size and slight increase of surface area, smaller grain size, lattice strain, and partial sulfur oxidation. The relationship between catalytic activity and property change manifests that the improved catalytic ability is mainly ascribed to the increase of surface area and surface oxidation induced by mechanical activation. This work provides novel insights into the improvement of catalytic performance of natural minerals by mechanical activation.展开更多
Kunming,a city in southwest China,has a climate that is different from most of the other places in the world because of its unique geographical characteristics.Due to its temperate climate,most of the residential buil...Kunming,a city in southwest China,has a climate that is different from most of the other places in the world because of its unique geographical characteristics.Due to its temperate climate,most of the residential buildings in this region are naturally ventilated.Accordingly,a winter thermal comfort study was conducted in Kunming to reveal the thermal response of residents.Indoor and outdoor environmental parameters were measured,and participants were investigated about their clothing,thermal sensations,thermal preferences,and thermal acceptance using online questionnaires.Data from 162 valid questionnaires were collected in the survey.Although the climate is referred to as“mild”,the survey showed that the indoor temperature during winter was lower than the typical comfort range.Nevertheless,the participants responded that most of them felt neutral and comfortable.The neutral temperature of participants living in Kunming was determined to be 16.96℃.The acceptable thermal sensation vote(TSV)range of the residents is-0.72 to 1.52.The acceptable indoor air temperature range is 15.03℃to 19.55℃,and the optimum indoor air temperature is 17.2℃.According to this study,the existing thermal comfort evaluation models can hardly predict residents’thermal responses in Kunming well.展开更多
Natural ventilation is driven by either buoyancy forces or wind pressure forces or their combinations that inherit stochastic variation into ventilation rates. Since the ventilation rate is a nonlinear function of mul...Natural ventilation is driven by either buoyancy forces or wind pressure forces or their combinations that inherit stochastic variation into ventilation rates. Since the ventilation rate is a nonlinear function of multiple variable factors including wind speed, wind direction, internal heat source and building structural thermal mass, the conventional methods for quantifying ventilation rate simply using dominant wind direction and average wind speed may not accurately describe the characteristic performance of natural ventilation. From a new point of view, the natural ventilation performance of a single room building under fluctuating wind speed condition using the Monte-Carlo simulation approach was investigated by incorporating building facade thermal mass effect. Given a same hourly turbulence intensity distribution, the wind speeds with 1 rain frequency fluctuations were generated using a stochastic model, the modified GARCH model. Comparisons of natural ventilation profiles, effective ventilation rates, and air conditioning electricity use for a three-month period show statistically significant differences （for 80% confidence interval） between the new calculations and the traditional methods based on hourly average wind speed.展开更多
In order to assess the differences between the human body thermal sensation in naturally ventilated space and that in air-conditioned space,the fuzzy evaluation model was adopted in the research of thermal sensation i...In order to assess the differences between the human body thermal sensation in naturally ventilated space and that in air-conditioned space,the fuzzy evaluation model was adopted in the research of thermal sensation in naturally ventilated space.Based on the questionnaires and field measurements,the membership functions were presented by the statistic of the covering frequency to the fuzzy subset.Dry-bulb temperature was taken as the only independent variable for membership functions.The maximum values of membership grades are all at 0.5 or so,which is a distinction character on thermal comfort of naturally ventilated space.By the calculating results of membership grades value to different fuzzy evaluation subsets,the Predicted Mean Vote(PMV)was obtained.Furthermore,energy coefficient(Ea)was introduced to calculate the energy consumption,and the prediction methods of residential building energy consumption were also discussed.Finally,the importance of evaluation model of thermal sense is shown through the energy consumption prediction in a specific residential building.展开更多
The effects of urban remnant natural evergreen broad-leaved forest (EBLF) on the restoration of artificial pine forests surrounding it were studied with reference to species composition,biodiversity,dominant species a...The effects of urban remnant natural evergreen broad-leaved forest (EBLF) on the restoration of artificial pine forests surrounding it were studied with reference to species composition,biodiversity,dominant species and stand structure on Mt. Tieshanping in Chongqing metropolis,Southwest China. The seeds from the remnant EBLF naturally facilitate the restoration process of artificial Pinus massoniana forests near it. The similarity of species composition between the artificial Pinus massoniana forests and the remnant EBLF and biodiversity index of the artificial Pinus massoniana forests decrease as the distance from the remnant EBLF increases. Castanopsis carlesii var. spinusa is the dominant species in the ground vegetation,shrub layer and sub-tree layer of the Pinus massoniana forests near the remnant EBLF. However,the natural restoration processes of those farther away from the remnant EBLF are restricted for the absence of seed source of the inherent components of the remnant EBLF,and the anthropogenic measures should be taken to facilitate the restoration process.展开更多
The large scale development of high natural gamma sandstones has been discovered in the Chang 73 Submember of the Triassic Yanchang Formation in the Ordos Basin, China. High natural gamma sandstones consist of terrige...The large scale development of high natural gamma sandstones has been discovered in the Chang 73 Submember of the Triassic Yanchang Formation in the Ordos Basin, China. High natural gamma sandstones consist of terrigenous detrital rocks with particle sizes ranging from silt to sand. They represent turbidite deposits characterized by high gamma ray values that are more than 180 American Petroleum Institute (API) units on a natural gamma ray log profile. For a long time, very high natural gamma sandstones had been identified as high-quality source rocks, such as oil shales, from conventional well log profiles, such as natural gamma ray well logs. Therefore, predicting the distribution of high natural gamma sandstones was studied. The sedimentary, lithological, and well log characteristics, as well as the genesis of the high radioactivity of high natural gamma sandstones were analyzed in the Chang 73 Submember. Thorium (Th), uranium (U) and other radioactive elements were found, carried by deep hydrothermal activity, and probably resulted in the formation of a relatively high radioactive zone in the cross-section, where high natural gamma sandstones usually develop in large quantities. This caused many turbidite sand bodies, which should have a continuous distribution in the cross-section, to appear to have a discontinuous distribution, when using conventional well log profiles, such as natural gamma ray well logs. From the above mentioned apparent discontinuous distribution of turbidite sand bodies in the cross-section, a continuous distribution can be predicted. It is obvious that the prediction of areas of continuous turbidite sand bodies in the cross-section usually corresponds with areas where high natural gamma sandstones are developed in large quantities. Exploration and development practice demonstrated that the developed method is fast and effective in predicting high natural gamma sandstones in the Chang 73 Submember.展开更多
基金Funding support for the Crop Pest Surveillance and Advisory Project(CROPSAP)。
文摘Background Cotton crop is infested by numerous arthropod pests from sowing to harvesting,causing substantial direct and indirect yield losses.Knowledge of seasonal population trends and the relative occurrence of pests and their natural enemies is required to minimize the pest population and yield losses.In the current study,analysis of the seasonal population trend of pests and natural enemies and their relative occurrence on cultivars of three cotton species in Central India has been carried out.Results A higher number and diversity of sucking pests were observed during the vegetative cotton growth stage(60 days after sowing),declining as the crop matured.With the exception of cotton jassid(Amrasca biguttula biguttula Ishida),which caused significant crop damage mainly from August to September;populations of other sucking insects seldom reached economic threshold levels(ETL)throughout the studied period.The bollworm complex populations were minimal,except for the pink bollworm(Pectinophora gossypiella Saunders),which re-emerged as a menace to cotton crops during the cotton cropping season 2017–2018 due to resistance development against Bt-cotton.A reasonably good number of predatory arthropods,including coccinellids,lacewings,and spiders,were found actively preying on the arthropod pest complex of the cotton crop during the early vegetative growth stage.Linear regression indicates a significant relationship between green boll infestations and pink bollworm moths in pheromone traps.Multiple linear regression analyse showed mean weekly weather at one-or two-week lag periods had a significant impact on sucking pest population(cotton aphid,cotton jassid,cotton whitefly,and onion thrips)fluctuation.Gossypium hirsutum cultivars RCH 2 and DCH 32,and G.barbadense cultivar Suvin were found susceptible to cotton jassid and onion thrips.Phule Dhanvantary,an G.arboreum cotton cultivar,demonstrated the highest tolerance among all evaluated cultivars against all sucking pests.Conclusion These findings have important implications for pest management in cotton crops.Susceptible cultivars warrant more attention for plant protection measures,making them more input-intensive.The choice of appropriate cultivars can help minimize input costs,thereby increasing net returns for cotton farmers.
基金supported by a grant from The National Natural Science Foundation of China(32000997)。
文摘Spores and pollen,as ubiquitous organisms found in nature,possess a remarkable core-shell structure and intricate surface morphology.These tiny particles are notable for their dimensional uniformity,sustainable utilization,environmental friendliness,porosity,amphiphilicity,and strong adhesive properties.In addition,they display excellent biocompatibility and biodegradability,which significantly enhances the stability and targeting of drugs within the body.Spores and pollen can be extracted using methods such as acidic solutions,alkaline solutions,or enzyme treatments to obtain sporopollenin,which is an extremely resilient and chemically inert complex biopolymer.The sporopollenin extracted through this process removes the original bioactive substances,such as cell nuclei,enzymes,and DNA,providing greater drug loading capacity and containing no potential allergens or immunogens,thus further enhancing its drug loading capacity and improving safety in therapeutic applications.Due to these beneficial attributes,spores,pollen and sporopollenin have gained widespread use in a variety of drug delivery systems,such as targeted delivery,sustained drug delivery,toxicity mitigation,flavor masking,vaccine delivery,delivery of labile substances,and other applications.This review introduces the types of natural spores and pollen commonly used in drug delivery systems,including their main components,common effects,and uses in drug delivery systems,and so on.It subsequently summarizes novel optimization methods in their processing,such as physical treatment,surface modification,and chemical modification,which enable higher drug loading efficiency,stability,and targeting,among other benefits.Additionally,this paper reviews the research progress and applications of natural spores,pollen,and sporopollenin in drug delivery systems,while also touching on some innovative research content,such as novel nanomotor microcarriers developed based on pollen.Based on these research findings,we further elaborate on the advantages of spores,pollen,and sporopollenin in drug delivery systems.For example,they have high stability and drug loading capacity,good adhesion,excellent targeting,and are easy to modify functionally.Currently,they show promising prospects in the fields of targeted drug delivery,sustained-release drug delivery,as well as the delivery of drugs that are effective but slightly toxic,and are often used in research on the treatment of diseases such as cancer and inflammation.We have also highlighted the challenges they face in various applications and identified some issues that need to be addressed,including difficulties in largescale production,the need to improve extraction and purification processes,and the existence of a low but still noteworthy risk of allergies,in order to fully leverage their potential in drug delivery applications.According to current research,although spores,pollen,and sporopollenin face some unresolved issues in clinical drug delivery,they still have great potential overall and are expected to become a new generation of green drug delivery platforms.In the future,further research into their unique physical and chemical properties and structural characteristics will help develop more efficient and stable drug delivery systems to meet diverse treatment needs.We believe that continued exploration of natural spores,pollen,and sporopollenin will drive this emerging field to achieve continuous breakthroughs and progress,ultimately making an important contribution to the cause of human health.
基金Project(2017YFE0102800)supported by the National Key R&D Program of ChinaProject(19JCYBJC21200)supported by the Tianjin Natural Science Foundation,China。
文摘Research on dual-fuel(DF)engines has become increasingly important as engine manufacturers seek to reduce carbon dioxide emissions.There are significant advantages of using diesel pilot-ignited natural gas engines as DF engines.However,different combustion modes exist due to variations in the formation of the mixture.This research used a simulation model and numerical simulations to explore the combustion characteristics of high-pressure direct injection(HPDI),partially premixed compression ignition(PPCI),and double pilot injection premixed compression ignition(DPPCI)combustion modes under a low-medium load.The results revealed that the DPPCI combustion mode provides higher gross indicated thermal efficiency and more acceptable total hydrocarbon(THC)emission levels than the other modes.Due to its relatively good performance,an experimental study was conducted on the DPPCI mode engine to evaluate the impact of the diesel dual-injection strategy on the combustion process.In the DPPCI mode,a delay in the second pilot ignition injection time increased THC emissions(a maximum value of 4.27g/(kW·h)),decreased the emission of nitrogen oxides(a maximum value of 7.64 g/(kW·h)),increased and then subsequently decreased the gross indicated thermal efficiency values,which reached 50.4%under low-medium loads.
文摘Interest in the possibility of storing and transporting natural gas in the form of clathrate hydrates has been increasing in recent years, particularly in some gas-importing and exporting countries.The technologies necessary for realizing this possibility may be classified into those relevant to the four serial processes (a) the formation of a hydrate, (b) the processing (dewatering, pelletizing, etc. ) of the formed hydrate, (c) the storage and transportation of the processed hydrate, and (d) the regasification (dissociation) of the hydrate. The technological development of any of these processes is still at an early stage. For hydrate formation, for example, various rival operations have been proposed. However,many of them have never been subjected to actual tests for practical use. More efforts are required for examining the different hydrate-formation technologies and for rating them by comparison. The general design of the processing of the formed hydrate inevitably depends on both the hydrate-formation process and the storage/transportation process, hence it has a wide variability. The major uncertainty in the storage-process design lies in the as-yet unclarified utility of the "self-preservation" effect of the naturalgas hydrates. The process design as well as the relevant cost evaluation should strongly depend on whether the hydrates are well preserved at atmospheric pressure in large-scale storage facilities. The regasification process has been studied less extensively than the former processes. The state of the art of the technological development in each of the serial processes is reviewed, placing emphasis on the hydrate formation process.
基金Project(NHA13002)supported by Explore Research Project of the General Armament Department,ChinaProject(11072106)supported by the National Natural Science Foundation of China
文摘Non-pneumatic tire appears to have advantages over traditional pneumatic tire in terms of flat proof and maintenance free.A mechanical elastic wheel(MEW) with a non-pneumatic elastic outer ring which functions as air of pneumatic tire was presented.The structure of MEW was non-inflatable integrated configuration and the effect of hinges was accounted for only in tension. To establish finite element model of MEW, various nonlinear factors, such as geometrical nonlinearity, material nonlinearity and contact nonlinearity, were considered. Load characteristic test was conducted by tyre dynamic test-bed to obtain force-deflection curve. And the finite element model was validated through load characteristic test. Natural dynamic characteristics of the MEW and its influencing factors were investigated based on the finite element model. Simulation results show that the finite element model closely matched experimental wheel. The results also show that natural frequency is related to ground constraints, material properties, loads and torques. Influencing factors as above obviously affect the amplitude of mode of vibration, but have little effect on mode of vibration shape. The results can provide guidance for experiment research, structural optimization of MEW.
文摘Natural gas hydrates are a kind of nonpolluting and high quality energy resources for future, the reserves of which are about twice of the carbon of the current fossil energy (petroleum, natural gas and coal) on the earth. And it will be the most important energy for the 21st century. The energy balance and numerical simulation are applied to study the schemes of the natural gas hydrates production in this paper,and it is considered that both depressurization and thermal stimulation are effective methods for exploiting natural gas hydrates, and that the gas production of the thermal stimulation is higher than that of the depressurization. But thermal stimulation is non-economic because it requires large amounts of energy.Therefore the combination of the two methods is a preferable method for the current development of the natural gas hydrates. The main factors which influence the production of natural gas hydrates are: the temperature of injected water, the injection rate, the initial saturation of the hydrates and the initial temperature of the reservoir which is the most important factor.
文摘The kinetics of the thermal decomposition for a naturally ageing ammonium perchlorate(AP) and hydroxyl-terminated-polybutadiene(HTPB) base bleed composite propellant were investigated using a differential scanning calorimetry(DSC). The naturally ageing AP/HTPB base bleed propellant samples have been stored in a sealed plastic bag at room temperature(5-25 ℃) for more than 20 years. The experimental DSC results were obtained by placing samples(each about 1.5 mg) in a sealed pan under non-isothermal condition under different heating rates, 5.0, 10.0, 15.0, 20.0 and 30.0 ℃·min^(-1). The activation energy and pre-exponential factor were estimated based on the relationship between the exothermic peak temperature and the heating rate by Ozawa and Kissinger methods, respectively. The decomposition kinetic parameters is lower the values under laboratorial aging condition.
基金Universiti Kuala Lumpur(UniKL)the Ministry of Education Malaysia for providing the scholarship award+1 种基金financially support through UniKL Grant Scheme(STRG 15144)to the principal author in this projectHiCOE grant(6369107)from the Ministry of Education,Malaysia。
文摘The paper presents the investigation of the effect of alkaline treatment of sodium hydroxide(NaOH) on physical and dynamic mechanical analysis(DMA) viscoelastic properties of kenaf fibre filled natural rubber(NR)/thermoplastic polyurethane(TPU) composites.The treated kenaf fiber,NR and TPU were weighed and proportioned according to the required compositions and were blended using hot mixed Brabender machine.The polymer composites were then fabricated using the hot press to form a sample board.The sample was cut and prepared and water absorption,density,thickness swelling and DMA tests were performed.As far as physical properties are concerned,composites with the highest NR amount of shows the best results,which indicates good fiber bonding adhesion.The polymer composites with the highest amount of TPU shows the highest damping properties at high temperature.
基金supported by the National Natural Science Foundation of China (No. 50176051)the State Key Development Program for Basic Research of China (No. 2000026306).
文摘The effect of diluted solution's magnetization on induction time and growth period of natural gas hydrate (NGH) has been investigated in quiescent reaction system at pressure of 4. 5 MPa and temperature of 274 K with SDS as surfactant, by using volume fixed and pressure falling method. Experimental results show that magnetization will have effect on the induction time of NGH. After magnetization with magnetic field intensity of 0.33 T, the induction time of NGH has been reduced to 47 min (average) from 99 min (average) in which there is no magnetization. On the other hand, the induction time has been prolonged after magnetization of the diluted solution with magnetic field intensity of 0.05 T, 0. 11 T, 0.22 T, 0.44T. Especially with magnetic field intensity of 0.11 T, the induction time had even been prolonged to 431min (average). The effect of magnetization on the growth period of NGH has not been found at the experimental condition.
文摘Natural convection heat transfer from annular finned tubes was studied numerically. Effects of fin spacing, temperature difference and tube diameter on flow pathlines and local heat transfer were also studied. It was shown that pathlines remain mostly circular for different geometries. Moreover, the contributions of fin periphery, fin side and bare tube to heat transfer were specified. It was shown that the heat transfer per unit area of fin periphery can be several times that of other parts. Moreover, in higher finspacing, the heat transfer from the bare tube can be more important than fin sides.
文摘The processes involved in the major steps of successful revegetation of bauxite residues are examined.The first phase is the natural physical,chemical and microbial ripening of the profile.This involves allowing the profile to drain,dry,shrink and crack to depth,leaching of soluble salts,alkalinity and Na down out of the surface layers,acidification by direct carbonation and natural seeding of tolerant vegetation with an accumulation of organic matter near the surface and an attendant development of an active microbial community.Following ripening,the surface layer can be tilled and gypsum and organic matter(e.g.manures,composts,biosolids)incorporated.These amendments result in a further decrease in pH,increase in Ca and other exchangeable cations,increased leaching of Na(with a reduction in exchangeable Na and ESP),improved physical properties,particularly aggregation,and a large increase in microbial activity.Other important considerations include the choice of suitable plant species tolerant to salinity/sodicity and local environmental conditions and the addition of balanced fertilizer applications.
文摘Energy consumption of block-cutting machines represents a major cost item in the processing of travertines and other natural stones. Therefore, determining the optimum sawing conditions for a particular stone is of major importance in the natural stone-processing industry. An experimental study was carried out utilizing a fully instrumented block-cutter to investigate the sawing performances of five different types of travertine blocks during cutting with a circular diamond saw. The sawing tests were performed in the down-cutting mode. Performance measurements were determined by measuring the cutting speed and energy consumption. Then, specific energy was determined. The one main cutting parameter, cutting speed, was varied in the investigation of optimum cutting performance. Furthermore, some physico-mechanical properties of file travertine blocks were determined in the laboratory. As a result, it is found that the energy consumption （specific energy） of block cutting machines is highly affected by cutting speed. It is determined that specific energy value usually decreases when cutting speed increases. When the cutting speed is higher than the determined value, the diamond saw can become stuck in the travertine block; this situation can be a problem for the block-cutting machine. As a result, the optimum cutting speed obtained for the travertine mines examined is approximately 1.5-2.0 m/min.
基金Project(2020YFC1908802) supported by the National Key Research and Development Project of China。
文摘Natural minerals receive growing attention as inexpensive, green, and efficient catalysts for degradation of organic pollutants. Mechanical activation of natural chalcopyrite was conducted for improving the catalytic performance.Tetracycline degradation was evaluated in the presence of hydrogen peroxide and mechanically activated chalcopyrite.Tetracycline degradation at 100 min is 55.52%(Chp10), 68.97%(Chp30), 77.79%(Chp60), and 86.43%(Chp120),respectively, and the rate constant of pseudo-first-order kinetics is 0.0079, 0.0109, 0.0137 and 0.0192 min^(-1), respectively.Chalcopyrite samples were examined by multiple characterizations. Mechanical activation of natural chalcopyrite induces the decline of particle size and slight increase of surface area, smaller grain size, lattice strain, and partial sulfur oxidation. The relationship between catalytic activity and property change manifests that the improved catalytic ability is mainly ascribed to the increase of surface area and surface oxidation induced by mechanical activation. This work provides novel insights into the improvement of catalytic performance of natural minerals by mechanical activation.
基金Project(2018YFC0704500)supported by the National Key R&D Program of ChinaProjects(51838007,52130803)supported by the National Natural Science Foundation of China。
文摘Kunming,a city in southwest China,has a climate that is different from most of the other places in the world because of its unique geographical characteristics.Due to its temperate climate,most of the residential buildings in this region are naturally ventilated.Accordingly,a winter thermal comfort study was conducted in Kunming to reveal the thermal response of residents.Indoor and outdoor environmental parameters were measured,and participants were investigated about their clothing,thermal sensations,thermal preferences,and thermal acceptance using online questionnaires.Data from 162 valid questionnaires were collected in the survey.Although the climate is referred to as“mild”,the survey showed that the indoor temperature during winter was lower than the typical comfort range.Nevertheless,the participants responded that most of them felt neutral and comfortable.The neutral temperature of participants living in Kunming was determined to be 16.96℃.The acceptable thermal sensation vote(TSV)range of the residents is-0.72 to 1.52.The acceptable indoor air temperature range is 15.03℃to 19.55℃,and the optimum indoor air temperature is 17.2℃.According to this study,the existing thermal comfort evaluation models can hardly predict residents’thermal responses in Kunming well.
文摘Natural ventilation is driven by either buoyancy forces or wind pressure forces or their combinations that inherit stochastic variation into ventilation rates. Since the ventilation rate is a nonlinear function of multiple variable factors including wind speed, wind direction, internal heat source and building structural thermal mass, the conventional methods for quantifying ventilation rate simply using dominant wind direction and average wind speed may not accurately describe the characteristic performance of natural ventilation. From a new point of view, the natural ventilation performance of a single room building under fluctuating wind speed condition using the Monte-Carlo simulation approach was investigated by incorporating building facade thermal mass effect. Given a same hourly turbulence intensity distribution, the wind speeds with 1 rain frequency fluctuations were generated using a stochastic model, the modified GARCH model. Comparisons of natural ventilation profiles, effective ventilation rates, and air conditioning electricity use for a three-month period show statistically significant differences （for 80% confidence interval） between the new calculations and the traditional methods based on hourly average wind speed.
基金Supported by National Natural Science Foundation of China(50508035)the National Science Foundation for Post-doctoral Scientists of China(20070411121)
文摘In order to assess the differences between the human body thermal sensation in naturally ventilated space and that in air-conditioned space,the fuzzy evaluation model was adopted in the research of thermal sensation in naturally ventilated space.Based on the questionnaires and field measurements,the membership functions were presented by the statistic of the covering frequency to the fuzzy subset.Dry-bulb temperature was taken as the only independent variable for membership functions.The maximum values of membership grades are all at 0.5 or so,which is a distinction character on thermal comfort of naturally ventilated space.By the calculating results of membership grades value to different fuzzy evaluation subsets,the Predicted Mean Vote(PMV)was obtained.Furthermore,energy coefficient(Ea)was introduced to calculate the energy consumption,and the prediction methods of residential building energy consumption were also discussed.Finally,the importance of evaluation model of thermal sense is shown through the energy consumption prediction in a specific residential building.
基金Project(30700094) supported by the National Natural Science Foundation of ChinaProject (CSTC, 2008BB7187) supported by the Natural Science Foundation of CQ CSTC, China+2 种基金Project (20092x07104-003-02)supported by the National Science and Technology MinistrySubsidy from the Pro Natural Fund of Japan for 2007Research project for a sustainable development of economic and social structure dependent on the environment of the eastern coast of Asia from Tokyo University of Information
文摘The effects of urban remnant natural evergreen broad-leaved forest (EBLF) on the restoration of artificial pine forests surrounding it were studied with reference to species composition,biodiversity,dominant species and stand structure on Mt. Tieshanping in Chongqing metropolis,Southwest China. The seeds from the remnant EBLF naturally facilitate the restoration process of artificial Pinus massoniana forests near it. The similarity of species composition between the artificial Pinus massoniana forests and the remnant EBLF and biodiversity index of the artificial Pinus massoniana forests decrease as the distance from the remnant EBLF increases. Castanopsis carlesii var. spinusa is the dominant species in the ground vegetation,shrub layer and sub-tree layer of the Pinus massoniana forests near the remnant EBLF. However,the natural restoration processes of those farther away from the remnant EBLF are restricted for the absence of seed source of the inherent components of the remnant EBLF,and the anthropogenic measures should be taken to facilitate the restoration process.
基金Project(18GK28)supported by the Doctoral Scientific Research Starting Foundation for the Yulin University,ChinaProject(20106101110020)supported by the University Research Fund of Science and Technology Development Center of Ministry of Education,ChinaProject(BJ08133-3)supported by the Key Fund Project of Continental Dynamics National Key Laboratory of Northwest University,China
文摘The large scale development of high natural gamma sandstones has been discovered in the Chang 73 Submember of the Triassic Yanchang Formation in the Ordos Basin, China. High natural gamma sandstones consist of terrigenous detrital rocks with particle sizes ranging from silt to sand. They represent turbidite deposits characterized by high gamma ray values that are more than 180 American Petroleum Institute (API) units on a natural gamma ray log profile. For a long time, very high natural gamma sandstones had been identified as high-quality source rocks, such as oil shales, from conventional well log profiles, such as natural gamma ray well logs. Therefore, predicting the distribution of high natural gamma sandstones was studied. The sedimentary, lithological, and well log characteristics, as well as the genesis of the high radioactivity of high natural gamma sandstones were analyzed in the Chang 73 Submember. Thorium (Th), uranium (U) and other radioactive elements were found, carried by deep hydrothermal activity, and probably resulted in the formation of a relatively high radioactive zone in the cross-section, where high natural gamma sandstones usually develop in large quantities. This caused many turbidite sand bodies, which should have a continuous distribution in the cross-section, to appear to have a discontinuous distribution, when using conventional well log profiles, such as natural gamma ray well logs. From the above mentioned apparent discontinuous distribution of turbidite sand bodies in the cross-section, a continuous distribution can be predicted. It is obvious that the prediction of areas of continuous turbidite sand bodies in the cross-section usually corresponds with areas where high natural gamma sandstones are developed in large quantities. Exploration and development practice demonstrated that the developed method is fast and effective in predicting high natural gamma sandstones in the Chang 73 Submember.
