Nitrophenyl ferulate was synthesized in one step without the protection of the hydroxyl of ferulic acid in the presence of 1,3 dicyclohexylcarbodiimide(DCC) as the catalyst. Thus, 15 20 g of ferulic acid reacted with ...Nitrophenyl ferulate was synthesized in one step without the protection of the hydroxyl of ferulic acid in the presence of 1,3 dicyclohexylcarbodiimide(DCC) as the catalyst. Thus, 15 20 g of ferulic acid reacted with 18 07 g of 4 nitrophenol for 24 h at room temperature in the presence of 22 44 g of DCC. The crude product was recrystallized from CHCl 3 to give 16 00 g of 4 nitrophenyl ferulate and the yield was 82 5%. Elemental analysis, IR and 1H NMR techniques were used to prove the structure of the product.展开更多
以D-氨基葡萄糖盐酸盐、间硝基苯甲酸和对甲基苯甲酸为原料,先将氨基葡萄糖的羟基加以保护,然后以N,N-二环已基碳二亚胺(DCC)为脱水剂,合成N-硝基苯甲酰基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖.产品结构经傅里叶变换红外光谱(FT...以D-氨基葡萄糖盐酸盐、间硝基苯甲酸和对甲基苯甲酸为原料,先将氨基葡萄糖的羟基加以保护,然后以N,N-二环已基碳二亚胺(DCC)为脱水剂,合成N-硝基苯甲酰基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖.产品结构经傅里叶变换红外光谱(FT-IR)及核磁共振氢谱(1 H NMR)表征确认.研究表明:1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖、DCC和间硝基苯甲酸/对甲基苯甲酸的摩尔比为1∶1.5∶1.5,反应温度为40℃,反应时间为4h为最佳反应条件.展开更多
2-Thioxo-3-alkyl-5-phenylmethylidene-4-imidazolidinones 5 were synthesized via tandem aza-Wittig reaction with three component of vinyliminophosphorane 3,alkyl isocyanates and Na2S/HOAc.The reaction condition and the ...2-Thioxo-3-alkyl-5-phenylmethylidene-4-imidazolidinones 5 were synthesized via tandem aza-Wittig reaction with three component of vinyliminophosphorane 3,alkyl isocyanates and Na2S/HOAc.The reaction condition and the spectral properties of cyclized compounds were researched.All the structures of cyclized products were confirmed by elemental analysis,IR,1H NMR and MS.展开更多
The title compound was obtained as a by product in a contraction reaction by using DIC as a coupling reagent. X ray diffraction shows the title compound is a pyrrolinenitroxide radical urea. Two crystallographically i...The title compound was obtained as a by product in a contraction reaction by using DIC as a coupling reagent. X ray diffraction shows the title compound is a pyrrolinenitroxide radical urea. Two crystallographically independent molecules possess different conformations but the identical bond distances and angles. Based on the molecular structure a possible reaction mechanism is proposed for the reaction of DIC and carboxylic acid.展开更多
文摘Nitrophenyl ferulate was synthesized in one step without the protection of the hydroxyl of ferulic acid in the presence of 1,3 dicyclohexylcarbodiimide(DCC) as the catalyst. Thus, 15 20 g of ferulic acid reacted with 18 07 g of 4 nitrophenol for 24 h at room temperature in the presence of 22 44 g of DCC. The crude product was recrystallized from CHCl 3 to give 16 00 g of 4 nitrophenyl ferulate and the yield was 82 5%. Elemental analysis, IR and 1H NMR techniques were used to prove the structure of the product.
文摘以D-氨基葡萄糖盐酸盐、间硝基苯甲酸和对甲基苯甲酸为原料,先将氨基葡萄糖的羟基加以保护,然后以N,N-二环已基碳二亚胺(DCC)为脱水剂,合成N-硝基苯甲酰基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖.产品结构经傅里叶变换红外光谱(FT-IR)及核磁共振氢谱(1 H NMR)表征确认.研究表明:1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖、DCC和间硝基苯甲酸/对甲基苯甲酸的摩尔比为1∶1.5∶1.5,反应温度为40℃,反应时间为4h为最佳反应条件.
文摘2-Thioxo-3-alkyl-5-phenylmethylidene-4-imidazolidinones 5 were synthesized via tandem aza-Wittig reaction with three component of vinyliminophosphorane 3,alkyl isocyanates and Na2S/HOAc.The reaction condition and the spectral properties of cyclized compounds were researched.All the structures of cyclized products were confirmed by elemental analysis,IR,1H NMR and MS.
文摘The title compound was obtained as a by product in a contraction reaction by using DIC as a coupling reagent. X ray diffraction shows the title compound is a pyrrolinenitroxide radical urea. Two crystallographically independent molecules possess different conformations but the identical bond distances and angles. Based on the molecular structure a possible reaction mechanism is proposed for the reaction of DIC and carboxylic acid.
