Cognitive bias,stemming from electronic measurement error and variability in human perception,exists in cognitive electronic warfare and affects the outcomes of conflicts.In this paper,the dynamic game approach is emp...Cognitive bias,stemming from electronic measurement error and variability in human perception,exists in cognitive electronic warfare and affects the outcomes of conflicts.In this paper,the dynamic game approach is employed to develop a model for cognitive bias induced by incomplete information and measurement errors in cognitive radar countermeasures.The payoffs for both parties are calculated using the radar's anti-jamming strategy matrix A and the jammer's jamming strategy matrix B.With perfect Bayesian equilibrium,a dynamic radar countermeasure model is established,and the impact of cognitive bias is analyzed.Drawing inspiration from the cognitive bias analysis method used in stock market trading,a cognitive bias model for cognitive radar countermeasures is introduced,and its correctness is mathematically proved.A gaming scenario involving the AN/SPY-1 radar and a smart jammer is set up to analyze the influence of cognitive bias on game outcomes.Simulation results validate the effectiveness of the proposed method.展开更多
To solve the problem of the low interference success rate of air defense missile radio fuzes due to the unified interference form of the traditional fuze interference system,an interference decision method based Q-lea...To solve the problem of the low interference success rate of air defense missile radio fuzes due to the unified interference form of the traditional fuze interference system,an interference decision method based Q-learning algorithm is proposed.First,dividing the distance between the missile and the target into multiple states to increase the quantity of state spaces.Second,a multidimensional motion space is utilized,and the search range of which changes with the distance of the projectile,to select parameters and minimize the amount of ineffective interference parameters.The interference effect is determined by detecting whether the fuze signal disappears.Finally,a weighted reward function is used to determine the reward value based on the range state,output power,and parameter quantity information of the interference form.The effectiveness of the proposed method in selecting the range of motion space parameters and designing the discrimination degree of the reward function has been verified through offline experiments involving full-range missile rendezvous.The optimal interference form for each distance state has been obtained.Compared with the single-interference decision method,the proposed decision method can effectively improve the success rate of interference.展开更多
Objective:Inflammation in the central nervous system plays a crucial role in the occurrence and development of sepsis-associated encephalopathy.This study aims to explore the effects of maresin 1(MaR1),an anti-inflamm...Objective:Inflammation in the central nervous system plays a crucial role in the occurrence and development of sepsis-associated encephalopathy.This study aims to explore the effects of maresin 1(MaR1),an anti-inflammatory and pro-resolving lipid mediator,on sepsis-induced neuroinflammation and cognitive impairment.Methods:Mice were randomly assigned to 4 groups:A sham group(sham operation+vehicle),a cecal ligation and puncture(CLP)group(CLP operation+vehicle),a MaR1-LD group(CLP operation+1 ng MaR1),and a MaR1-HD group(CLP operation+10 ng MaR1).MaR1 or vehicle was intraperitoneally administered starting 1 h before CLP operation,then every other day for 7 days.Survival rates were monitored,and serum inflammatory cytokines[tumor necrosis factor alpha(TNF-α),interleukin(IL)-1β,and IL-6]were measured 24 h after operation using enzyme-linked immunosorbent assay(ELISA).Cognitive function was assessed 7 days after operation using the Morris water maze(MWM)test and novel object recognition(NOR)task.The mRNA expression of TNF-α,IL-1β,IL-6,inducible nitric oxide synthase(iNOS),IL-4,IL-10,and arginase 1(Arg1)in cortical and hippocampal tissues was determined by real-time reverse transcription PCR(RT-PCR).Western blotting was used to determine the protein expression of iNOS,Arg1,signal transducer and activator of transcription 6(STAT6),peroxisome proliferator-activated receptor gamma(PPARγ),and phosphorylated STAT6(p-STAT6)in hippocampal tissue.Microglia activation was visualized via immunofluorescence.Mice were also treated with the PPARγantagonist GW9662 to confirm the involvement of this pathway in MaR1’s effects.Results:CLP increased serum levels of TNF-α,IL-1β,and IL-6,and reduced body weight and survival rates(all P<0.05).Both 1 ng and 10 ng doses of MaR1 significantly reduced serum TNF-α,IL-1β,and IL-6 levels,improved body weight,and increased survival rates(all P<0.05).No significant difference in efficacy was observed between the 2 doses(all P>0.05).MWM test and NOR task indicated that CLP impaired spatial learning,which MaR1 mitigated.However,GW9662 partially reversed MaR1’s protective effects.Real-time RTPCR results demonstrated that,compared to the sham group,mRNA expression of TNF-α,IL-1β,and iNOS significantly increased in hippocampal tissues following CLP(all P<0.05),while IL-4,IL-10,and Arg1 showed a slight decrease,though the differences were not statistically significant(all P>0.05).Compared to the CLP group,both 1 ng and 10 ng MaR1 decreased TNF-α,IL-1β,and iNOS mRNA expression in hippocampal tissues and increased IL-4,IL-10,and Arg1 mRNA expression(all P<0.05).Immunofluorescence results indicated a significant increase in Iba1-positive microglia in the hippocampus after CLP compared to the sham group(P<0.05).Administration of 1 ng and 10 ng MaR1 reduced the percentage area of Iba1-positive cells in the hippocampus compared to the CLP group(both P<0.05).Western blotting results showed that,compared to the CLP group,both 1 ng and 10 ng MaR1 down-regulated the iNOS expression,while up-regulated the expression of Arg1,PPARγ,and p-STAT6(all P<0.05).However,the inclusion of GW9662 counteracted the MaR1-induced upregulation of Arg1 and PPARγcompared to the MaR1-LD group(all P<0.05).Conclusion:MaR1 inhibits the classical activation of hippocampal microglia,promotes alternative activation,reduces sepsis-induced neuroinflammation,and improves cognitive decline.展开更多
Objective Chronic stress can induce cognitive dysfunction,but the underlying mechanisms remain unknown.Studies have confirmed that the high mobility group box 1/Toll-like receptor 4(HMGB1/TLR4)pathway is closely assoc...Objective Chronic stress can induce cognitive dysfunction,but the underlying mechanisms remain unknown.Studies have confirmed that the high mobility group box 1/Toll-like receptor 4(HMGB1/TLR4)pathway is closely associated with cognitive impairment.Therefore,this research aimed to explore whether the HMGB1/TLR4 pathway involves in chronic stress-induced cognitive dysfunction.Methods The chronic unpredictable mild stress(CUMS)mouse model was established by randomly giving different types of stress every day for four consecutive weeks.Cognitive function was detected by novel object recognition test,Y-maze test,and Morris water maze test.The protein expressions of HMGB1,TLR4,B-cell lymphoma 2(BCL2),and BCL2 associated X(BAX)were determined by Western blot.The damage of neurons in the hippocampal CA1 region was observed by hematoxylin-eosin(HE)staining.Results The protein expressions of HMGB1 and TLR4 were significantly increased in the hippocampus of chronic stress mice.Furthermore,inhibition of the HMGB1/TLR4 pathway induced by ethyl pyruvate(EP,a specific inhibitor of HMGB1)and TAK242(a selective inhibitor of TLR4)treatment attenuated cognitive impairment in chronic stress mice,according to the novel object recognition test,Y-maze test,and Morris water maze test.In addition,administration of EP and TAK242 also mitigated the increase of apoptosis in the hippocampus of chronic stress mice.Conclusion These results indicate that the hippocampal HMGB1/TLR4 pathway contributes to chronic stress-induced apoptosis and cognitive dysfunction.展开更多
Alzheimer's disease(AD)is a prevalent neurodegenerative disease characterized by cognitive decline in the early stage.Mild cognitive impairment(MCI)is considered as an intermediate stage between normal aging and A...Alzheimer's disease(AD)is a prevalent neurodegenerative disease characterized by cognitive decline in the early stage.Mild cognitive impairment(MCI)is considered as an intermediate stage between normal aging and AD.In recent years,studies related to resting-state functional MRI(rs-fMRI)indicated that the occurrence and development process of MCI and AD might be closely linked to spontaneous brain activity and alterations in functional connectivity among brain regions,and rs-fMRI could provide important reference for specific diagnosis and early treatment of MCI and AD.The research progresses of rs-fMRI for MCI and AD were reviewed in this article.展开更多
A novel distributed cognitive radio multichannel medium access protocol without common control channel was proposed.The protocol divided a transmission interval into two parts for exchanging control information and da...A novel distributed cognitive radio multichannel medium access protocol without common control channel was proposed.The protocol divided a transmission interval into two parts for exchanging control information and data,respectively.In addition to evaluating system saturation throughput of the proposed protocol,a three-dimensional multi channel Markov chain model to describe the sate of the cognitive users (CUs) in dynamic spectrum access was presented.The proposed analysis was applied to the packet transmission schemes employed by the basic,RTS/CTS access mechanism adopted in the normal IEEE 802.11.Analyzing the advantage of the two methods,a hybrid access mechanism was proposed to improve the system throughput.The simulation results show that the experiment results are close to the value computed by the model (less than 5%),and the proposed protocol significantly improves the performance of the system throughput by borrowing the licensed spectrum.By analyzing the dependence of throughput on system parameters,hybrid mechanism dynamically selecting access mechanism can maintain high throughput.展开更多
In order to make full use of the driver’s long-term driving experience in the process of perception, interaction and vehicle control of road traffic information, a driving behavior rule extraction algorithm based on ...In order to make full use of the driver’s long-term driving experience in the process of perception, interaction and vehicle control of road traffic information, a driving behavior rule extraction algorithm based on artificial neural network interface(ANNI) and its integration is proposed. Firstly, based on the cognitive learning theory, the cognitive driving behavior model is established, and then the cognitive driving behavior is described and analyzed. Next, based on ANNI, the model and the rule extraction algorithm(ANNI-REA) are designed to explain not only the driving behavior but also the non-sequence. Rules have high fidelity and safety during driving without discretizing continuous input variables. The experimental results on the UCI standard data set and on the self-built driving behavior data set, show that the method is about 0.4% more accurate and about 10% less complex than the common C4.5-REA, Neuro-Rule and REFNE. Further, simulation experiments verify the correctness of the extracted driving rules and the effectiveness of the extraction based on cognitive driving behavior rules. In general, the several driving rules extracted fully reflect the execution mechanism of sequential activity of driving comprehensive cognition, which is of great significance for the traffic of mixed traffic flow under the network of vehicles and future research on unmanned driving.展开更多
The command and control（C2） is a decision-making process based on human cognition,which contains operational,physical,and human characteristics,so it takes on uncertainty and complexity.As a decision support approac...The command and control（C2） is a decision-making process based on human cognition,which contains operational,physical,and human characteristics,so it takes on uncertainty and complexity.As a decision support approach,Bayesian networks（BNs） provide a framework in which a decision is made by combining the experts＇ knowledge and the specific data.In addition,an expert system represented by human cognitive framework is adopted to express the real-time decision-making process of the decision maker.The combination of the Bayesian decision support and human cognitive framework in the C2 of a specific application field is modeled and executed by colored Petri nets（CPNs）,and the consequences of execution manifest such combination can perfectly present the decision-making process in C2.展开更多
In order to avoid the system performance deterioration caused by the wireless fading channel and imperfect channel estimation in cognitive radio networks, the spectrum sharing problem with the consideration of feedbac...In order to avoid the system performance deterioration caused by the wireless fading channel and imperfect channel estimation in cognitive radio networks, the spectrum sharing problem with the consideration of feedback control information from the primary user is analyzed. An improved spectrum sharing algorithm based on the combination of the feedback control information and the optimization algorithm is proposed. The relaxation method is used to achieve the approximate spectrum sharing model, and the spectrum sharing strategy that satisfies the individual outage probability constraints can be obtained iteratively with the observed outage probability. Simulation results show that the proposed spectrum sharing algorithm can achieve the spectrum sharing strategy that satisfies the outage probability constraints and reduce the average outage probability without causing maximum transmission rate reduction of the secondary user.展开更多
In order to solve discrete multi-objective optimization problems, a non-dominated sorting quantum particle swarm optimization (NSQPSO) based on non-dominated sorting and quantum particle swarm optimization is proposed...In order to solve discrete multi-objective optimization problems, a non-dominated sorting quantum particle swarm optimization (NSQPSO) based on non-dominated sorting and quantum particle swarm optimization is proposed, and the performance of the NSQPSO is evaluated through five classical benchmark functions. The quantum particle swarm optimization (QPSO) applies the quantum computing theory to particle swarm optimization, and thus has the advantages of both quantum computing theory and particle swarm optimization, so it has a faster convergence rate and a more accurate convergence value. Therefore, QPSO is used as the evolutionary method of the proposed NSQPSO. Also NSQPSO is used to solve cognitive radio spectrum allocation problem. The methods to complete spectrum allocation in previous literature only consider one objective, i.e. network utilization or fairness, but the proposed NSQPSO method, can consider both network utilization and fairness simultaneously through obtaining Pareto front solutions. Cognitive radio systems can select one solution from the Pareto front solutions according to the weight of network reward and fairness. If one weight is unit and the other is zero, then it becomes single objective optimization, so the proposed NSQPSO method has a much wider application range. The experimental research results show that the NSQPS can obtain the same non-dominated solutions as exhaustive search but takes much less time in small dimensions; while in large dimensions, where the problem cannot be solved by exhaustive search, the NSQPSO can still solve the problem, which proves the effectiveness of NSQPSO.展开更多
The status of an operator’s situation awareness is one of the critical factors that influence the quality of the missions.Thus the measurement method of the situation awareness status is an important topic to researc...The status of an operator’s situation awareness is one of the critical factors that influence the quality of the missions.Thus the measurement method of the situation awareness status is an important topic to research.So far,there are lots of methods designed for the measurement of situation awareness status,but there is no model that can measure it accurately in real-time,so this work is conducted to deal with such a gap.Firstly,collect the relevant physiological data of operators while they are performing a specific mission,simultaneously,measure their status of situation awareness by using the situation awareness global assessment technique(SAGAT),which is known for accuracy but cannot be used in real-time.And then,after the preprocessing of the raw data,use the physiological data as features,the SAGAT’s results as a label to train a fuzzy cognitive map(FCM),which is an explainable and powerful intelligent model.Also,a hybrid learning algorithm of particle swarm optimization(PSO)and gradient descent is proposed for the FCM training.The final results show that the learned FCM can assess the status of situation awareness accurately in real-time,and the proposed hybrid learning algorithm has better efficiency and accuracy.展开更多
In this paper,a blind multiband spectrum sensing(BMSS)method requiring no knowledge of noise power,primary signal and wireless channel is proposed based on the K-means clustering(KMC).In this approach,the KMC algorith...In this paper,a blind multiband spectrum sensing(BMSS)method requiring no knowledge of noise power,primary signal and wireless channel is proposed based on the K-means clustering(KMC).In this approach,the KMC algorithm is used to identify the occupied subband set(OSS)and the idle subband set(ISS),and then the location and number information of the occupied channels are obtained according to the elements in the OSS.Compared with the classical BMSS methods based on the information theoretic criteria(ITC),the new method shows more excellent performance especially in the low signal-to-noise ratio(SNR)and the small sampling number scenarios,and more robust detection performance in noise uncertainty or unequal noise variance applications.Meanwhile,the new method performs more stablely than the ITC-based methods when the occupied subband number increases or the primary signals suffer multi-path fading.Simulation result verifies the effectiveness of the proposed method.展开更多
Cognitive radio（CR） technology is considered to be an effective solution to allocate spectrum resources,whereas the primary users of a network do not fully utilize available frequency bands.Spectrum auction framewor...Cognitive radio（CR） technology is considered to be an effective solution to allocate spectrum resources,whereas the primary users of a network do not fully utilize available frequency bands.Spectrum auction framework has been recognized as an effective way to achieve dynamic spectrum access.From the perspective of spectrum auction,multi-band multi-user auction provides a new challenge for spectrum management.This paper proposes an auction framework based on location information for multi-band multi-user spectrum allocation.The performance of the proposed framework is compared with that of traditional auction framework based on a binary interference model as a benchmark.Simulation results show that primary users will obtain more total system revenue by selling their idle frequency bands to secondary users and the spectrum utilization of the proposed framework is more effective and fairer.展开更多
In cognitive radio network(CRN), a secondary user(SU) may utilize the spectrum resource of the primary user(PU) and avoid causing harmful interference to the primary network(PN) via spectrum sensing. In the traditiona...In cognitive radio network(CRN), a secondary user(SU) may utilize the spectrum resource of the primary user(PU) and avoid causing harmful interference to the primary network(PN) via spectrum sensing. In the traditional time spectrum sensing, the SU cannot detect the PU's presence during its transmission, thus increasing interference to the PN. In this work, a novel weighed cooperative bandwidth spectrum sensing method is proposed, which allows multiple SUs to use part of the bandwidth to perform cooperative spectrum sensing throughout the whole frame in order to detect the PU's reappearance in time. The SU's spectrum efficiency is maximized by jointly optimizing sensing bandwidth proportion, number of cooperative SUs and detection probability, subject to the constraints on the SU's interference and the false alarm probability. Simulation results show significant decrease on the interference and improvement on the spectrum efficiency using the proposed weighed cooperative bandwidth spectrum sensing method.展开更多
A multi-objective optimization based robust beamforming(BF)scheme is proposed to realize secure transmission in a cognitive satellite and unmanned aerial vehicle(UAV)network.Since the satellite network coexists with t...A multi-objective optimization based robust beamforming(BF)scheme is proposed to realize secure transmission in a cognitive satellite and unmanned aerial vehicle(UAV)network.Since the satellite network coexists with the UAV network,we first consider both achievable secrecy rate maximization and total transmit power minimization,and formulate a multi-objective optimization problem(MOOP)using the weighted Tchebycheff approach.Then,by supposing that only imperfect channel state information based on the angular information is available,we propose a method combining angular discretization with Taylor approximation to transform the non-convex objective function and constraints to the convex ones.Next,we adopt semi-definite programming together with randomization technology to solve the original MOOP and obtain the BF weight vector.Finally,simulation results illustrate that the Pareto optimal trade-off can be achieved,and the superiority of our proposed scheme is confirmed by comparing with the existing BF schemes.展开更多
Interference suppression is a challenge for radar researchers, especially when mainlobe and sidelobe interference coexist. We present a comprehensive anti-interference approach based on a cognitive bistatic airborne r...Interference suppression is a challenge for radar researchers, especially when mainlobe and sidelobe interference coexist. We present a comprehensive anti-interference approach based on a cognitive bistatic airborne radar. The risk of interception is reduced by lowering the launch energy of the radar transmitting terminal in the direction of interference;main lobe and sidelobe interferences are suppressed via cooperation between the two radars. The interference received by a single radar is extracted from the overall radar signal using multiple signal classification(MUSIC), and the interference is cross-located using two different azimuthal angles. Neural networks allowing good, non-linear nonparametric approximations are used to predict the location of interference, and this information is then used to preset the transmitting notch antenna to reduce the likelihood of interception. To simultaneously suppress mainlobe and sidelobe interferences, a blocking matrix is used to mask mainlobe interference based on azimuthal information, and an adaptive process is used to suppress sidelobe interference. Mainlobe interference is eliminated using the data received by the two radars. Simulation verifies the performance of the model.展开更多
This paper investigates the jamming sensing performance of the simultaneous transmit and receive based cognitive anti-jamming(SCAJ) receiver impaired by phase noise in local oscillators(LO) over fading channels. First...This paper investigates the jamming sensing performance of the simultaneous transmit and receive based cognitive anti-jamming(SCAJ) receiver impaired by phase noise in local oscillators(LO) over fading channels. Firstly, energy detection(ED)based on the jamming to noise ratio(JNR) of the high frequency bands SCAJ receiver with phase noise under different channels is analyzed. Then, the probabilities of jamming detection and false alarm in closed-form for the SCAJ receiver are derived. Finally,the modified Bayesian Cramer-Rao bound(BCRB) of jamming sensing for the SCAJ receiver is presented. Simulation results show that the performance degradation of the SCAJ system due to phase noise is more severe than that due to the channel fading in the circumstances where the signal bandwidth(BW) is kept a constant. Moreover, the signal BW has an effect on the phase noise in LO, and the jamming detection probability of the wideband SCAJ receiver with lower phase noise outperforms that of the narrowband receiver using the same center frequency. Furthermore,an accurate phase noise estimation and compensation scheme can improve the jamming detection capability of the SCAJ receiver in high frequency bands and approach to the upper bound.展开更多
For acquiring high energy efficiency and the maximal throughput, a new time slot structure is designed for energy harvesting(EH) cognitive radio(CR). Considering the CR system with EH and cooperative relay, a best coo...For acquiring high energy efficiency and the maximal throughput, a new time slot structure is designed for energy harvesting(EH) cognitive radio(CR). Considering the CR system with EH and cooperative relay, a best cooperative mechanism(BCM)is proposed for CR with EH. To get the optimal estimation performance, a quantum fireworks algorithm(QFA) is designed to resolve the difficulties of maximal throughput and EH, and the proposed cooperative mechanism is called as QFA-BCM. The proposed QFA combines the advantages of quantum computation theory with the fireworks algorithm(FA). Thus the QFA is able to obtain the optimal solution and its convergence performance is proved. By using the new cooperation mechanism and computing algorithm, the proposed QFA-BCM method can achieve comparable maximal throughput in the new timeslot structure. Simulation results have proved that the QFA-BCM method is superior to previous non-cooperative and cooperative mechanisms.展开更多
An approach for modeling a human cognitive framework in time-stressed decision making is presented. The recognitive and metacognitive processes that represent the cognitive framework are modeled by the colored Petri n...An approach for modeling a human cognitive framework in time-stressed decision making is presented. The recognitive and metacognitive processes that represent the cognitive framework are modeled by the colored Petri nets （CPNs）. A structural and behavioral analysis method is adopted to obtain the static and dynamic property used to verify the CPNs model of the cognitive framework. Finally, an example from the command and control radar recognition system is used to evaluate the feasibility and availability of the CPNs model adopted in practical systems.展开更多
Based on the cognitive radar concept and the basic connotation of cognitive skywave over-the-horizon radar（SWOTHR）, the system structure and information processingmechanism about cognitive SWOTHR are researched. Amo...Based on the cognitive radar concept and the basic connotation of cognitive skywave over-the-horizon radar（SWOTHR）, the system structure and information processingmechanism about cognitive SWOTHR are researched. Amongthem, the hybrid network system architecture which is thedistributed configuration combining with the centralized cognition and its soft/hardware framework with the sense-detectionintegration are proposed, and the information processing framebased on the lens principle and its information processing flowwith receive-transmit joint adaption are designed, which buildand parse the work law for cognition and its self feedback adjustment with the lens focus model and five stages informationprocessing sequence. After that, the system simulation andthe performance analysis and comparison are provided, whichinitially proves the rationality and advantages of the proposedideas. Finally, four important development ideas of futureSWOTHR toward ＂high frequency intelligence information processing system＂ are discussed, which are scene information fusion, dynamic reconfigurable system, hierarchical and modulardesign, and sustainable development. Then the conclusion thatthe cognitive SWOTHR can cause the performance improvement is gotten.展开更多
文摘Cognitive bias,stemming from electronic measurement error and variability in human perception,exists in cognitive electronic warfare and affects the outcomes of conflicts.In this paper,the dynamic game approach is employed to develop a model for cognitive bias induced by incomplete information and measurement errors in cognitive radar countermeasures.The payoffs for both parties are calculated using the radar's anti-jamming strategy matrix A and the jammer's jamming strategy matrix B.With perfect Bayesian equilibrium,a dynamic radar countermeasure model is established,and the impact of cognitive bias is analyzed.Drawing inspiration from the cognitive bias analysis method used in stock market trading,a cognitive bias model for cognitive radar countermeasures is introduced,and its correctness is mathematically proved.A gaming scenario involving the AN/SPY-1 radar and a smart jammer is set up to analyze the influence of cognitive bias on game outcomes.Simulation results validate the effectiveness of the proposed method.
基金National Natural Science Foundation of China(61973037)National 173 Program Project(2019-JCJQ-ZD-324).
文摘To solve the problem of the low interference success rate of air defense missile radio fuzes due to the unified interference form of the traditional fuze interference system,an interference decision method based Q-learning algorithm is proposed.First,dividing the distance between the missile and the target into multiple states to increase the quantity of state spaces.Second,a multidimensional motion space is utilized,and the search range of which changes with the distance of the projectile,to select parameters and minimize the amount of ineffective interference parameters.The interference effect is determined by detecting whether the fuze signal disappears.Finally,a weighted reward function is used to determine the reward value based on the range state,output power,and parameter quantity information of the interference form.The effectiveness of the proposed method in selecting the range of motion space parameters and designing the discrimination degree of the reward function has been verified through offline experiments involving full-range missile rendezvous.The optimal interference form for each distance state has been obtained.Compared with the single-interference decision method,the proposed decision method can effectively improve the success rate of interference.
基金supported by the National Natural Science Foundation (81601728,31500726)the Natural Science Foundation of Hunan Province (2021JJ41002),China。
文摘Objective:Inflammation in the central nervous system plays a crucial role in the occurrence and development of sepsis-associated encephalopathy.This study aims to explore the effects of maresin 1(MaR1),an anti-inflammatory and pro-resolving lipid mediator,on sepsis-induced neuroinflammation and cognitive impairment.Methods:Mice were randomly assigned to 4 groups:A sham group(sham operation+vehicle),a cecal ligation and puncture(CLP)group(CLP operation+vehicle),a MaR1-LD group(CLP operation+1 ng MaR1),and a MaR1-HD group(CLP operation+10 ng MaR1).MaR1 or vehicle was intraperitoneally administered starting 1 h before CLP operation,then every other day for 7 days.Survival rates were monitored,and serum inflammatory cytokines[tumor necrosis factor alpha(TNF-α),interleukin(IL)-1β,and IL-6]were measured 24 h after operation using enzyme-linked immunosorbent assay(ELISA).Cognitive function was assessed 7 days after operation using the Morris water maze(MWM)test and novel object recognition(NOR)task.The mRNA expression of TNF-α,IL-1β,IL-6,inducible nitric oxide synthase(iNOS),IL-4,IL-10,and arginase 1(Arg1)in cortical and hippocampal tissues was determined by real-time reverse transcription PCR(RT-PCR).Western blotting was used to determine the protein expression of iNOS,Arg1,signal transducer and activator of transcription 6(STAT6),peroxisome proliferator-activated receptor gamma(PPARγ),and phosphorylated STAT6(p-STAT6)in hippocampal tissue.Microglia activation was visualized via immunofluorescence.Mice were also treated with the PPARγantagonist GW9662 to confirm the involvement of this pathway in MaR1’s effects.Results:CLP increased serum levels of TNF-α,IL-1β,and IL-6,and reduced body weight and survival rates(all P<0.05).Both 1 ng and 10 ng doses of MaR1 significantly reduced serum TNF-α,IL-1β,and IL-6 levels,improved body weight,and increased survival rates(all P<0.05).No significant difference in efficacy was observed between the 2 doses(all P>0.05).MWM test and NOR task indicated that CLP impaired spatial learning,which MaR1 mitigated.However,GW9662 partially reversed MaR1’s protective effects.Real-time RTPCR results demonstrated that,compared to the sham group,mRNA expression of TNF-α,IL-1β,and iNOS significantly increased in hippocampal tissues following CLP(all P<0.05),while IL-4,IL-10,and Arg1 showed a slight decrease,though the differences were not statistically significant(all P>0.05).Compared to the CLP group,both 1 ng and 10 ng MaR1 decreased TNF-α,IL-1β,and iNOS mRNA expression in hippocampal tissues and increased IL-4,IL-10,and Arg1 mRNA expression(all P<0.05).Immunofluorescence results indicated a significant increase in Iba1-positive microglia in the hippocampus after CLP compared to the sham group(P<0.05).Administration of 1 ng and 10 ng MaR1 reduced the percentage area of Iba1-positive cells in the hippocampus compared to the CLP group(both P<0.05).Western blotting results showed that,compared to the CLP group,both 1 ng and 10 ng MaR1 down-regulated the iNOS expression,while up-regulated the expression of Arg1,PPARγ,and p-STAT6(all P<0.05).However,the inclusion of GW9662 counteracted the MaR1-induced upregulation of Arg1 and PPARγcompared to the MaR1-LD group(all P<0.05).Conclusion:MaR1 inhibits the classical activation of hippocampal microglia,promotes alternative activation,reduces sepsis-induced neuroinflammation,and improves cognitive decline.
文摘Objective Chronic stress can induce cognitive dysfunction,but the underlying mechanisms remain unknown.Studies have confirmed that the high mobility group box 1/Toll-like receptor 4(HMGB1/TLR4)pathway is closely associated with cognitive impairment.Therefore,this research aimed to explore whether the HMGB1/TLR4 pathway involves in chronic stress-induced cognitive dysfunction.Methods The chronic unpredictable mild stress(CUMS)mouse model was established by randomly giving different types of stress every day for four consecutive weeks.Cognitive function was detected by novel object recognition test,Y-maze test,and Morris water maze test.The protein expressions of HMGB1,TLR4,B-cell lymphoma 2(BCL2),and BCL2 associated X(BAX)were determined by Western blot.The damage of neurons in the hippocampal CA1 region was observed by hematoxylin-eosin(HE)staining.Results The protein expressions of HMGB1 and TLR4 were significantly increased in the hippocampus of chronic stress mice.Furthermore,inhibition of the HMGB1/TLR4 pathway induced by ethyl pyruvate(EP,a specific inhibitor of HMGB1)and TAK242(a selective inhibitor of TLR4)treatment attenuated cognitive impairment in chronic stress mice,according to the novel object recognition test,Y-maze test,and Morris water maze test.In addition,administration of EP and TAK242 also mitigated the increase of apoptosis in the hippocampus of chronic stress mice.Conclusion These results indicate that the hippocampal HMGB1/TLR4 pathway contributes to chronic stress-induced apoptosis and cognitive dysfunction.
文摘Alzheimer's disease(AD)is a prevalent neurodegenerative disease characterized by cognitive decline in the early stage.Mild cognitive impairment(MCI)is considered as an intermediate stage between normal aging and AD.In recent years,studies related to resting-state functional MRI(rs-fMRI)indicated that the occurrence and development process of MCI and AD might be closely linked to spontaneous brain activity and alterations in functional connectivity among brain regions,and rs-fMRI could provide important reference for specific diagnosis and early treatment of MCI and AD.The research progresses of rs-fMRI for MCI and AD were reviewed in this article.
基金Project(61071104) supported by the National Natural Science Foundation of China
文摘A novel distributed cognitive radio multichannel medium access protocol without common control channel was proposed.The protocol divided a transmission interval into two parts for exchanging control information and data,respectively.In addition to evaluating system saturation throughput of the proposed protocol,a three-dimensional multi channel Markov chain model to describe the sate of the cognitive users (CUs) in dynamic spectrum access was presented.The proposed analysis was applied to the packet transmission schemes employed by the basic,RTS/CTS access mechanism adopted in the normal IEEE 802.11.Analyzing the advantage of the two methods,a hybrid access mechanism was proposed to improve the system throughput.The simulation results show that the experiment results are close to the value computed by the model (less than 5%),and the proposed protocol significantly improves the performance of the system throughput by borrowing the licensed spectrum.By analyzing the dependence of throughput on system parameters,hybrid mechanism dynamically selecting access mechanism can maintain high throughput.
基金Project(2017YFB0102503)supported by the National Key Research and Development Program of ChinaProjects(U1664258,51875255,61601203)supported by the National Natural Science Foundation of China+1 种基金Projects(DZXX-048,2018-TD-GDZB-022)supported by the Jiangsu Province’s Six Talent Peak,ChinaProject(18KJA580002)supported by Major Natural Science Research Project of Higher Learning in Jiangsu Province,China
文摘In order to make full use of the driver’s long-term driving experience in the process of perception, interaction and vehicle control of road traffic information, a driving behavior rule extraction algorithm based on artificial neural network interface(ANNI) and its integration is proposed. Firstly, based on the cognitive learning theory, the cognitive driving behavior model is established, and then the cognitive driving behavior is described and analyzed. Next, based on ANNI, the model and the rule extraction algorithm(ANNI-REA) are designed to explain not only the driving behavior but also the non-sequence. Rules have high fidelity and safety during driving without discretizing continuous input variables. The experimental results on the UCI standard data set and on the self-built driving behavior data set, show that the method is about 0.4% more accurate and about 10% less complex than the common C4.5-REA, Neuro-Rule and REFNE. Further, simulation experiments verify the correctness of the extracted driving rules and the effectiveness of the extraction based on cognitive driving behavior rules. In general, the several driving rules extracted fully reflect the execution mechanism of sequential activity of driving comprehensive cognition, which is of great significance for the traffic of mixed traffic flow under the network of vehicles and future research on unmanned driving.
基金supported by the National Natural Science Foundation of China (60874068)
文摘The command and control（C2） is a decision-making process based on human cognition,which contains operational,physical,and human characteristics,so it takes on uncertainty and complexity.As a decision support approach,Bayesian networks（BNs） provide a framework in which a decision is made by combining the experts＇ knowledge and the specific data.In addition,an expert system represented by human cognitive framework is adopted to express the real-time decision-making process of the decision maker.The combination of the Bayesian decision support and human cognitive framework in the C2 of a specific application field is modeled and executed by colored Petri nets（CPNs）,and the consequences of execution manifest such combination can perfectly present the decision-making process in C2.
基金supported by the National Natural Science Foundation of China (61073183)the Natural Science Foundation for the Youth of Heilongjiang Province (QC2012C070)
文摘In order to avoid the system performance deterioration caused by the wireless fading channel and imperfect channel estimation in cognitive radio networks, the spectrum sharing problem with the consideration of feedback control information from the primary user is analyzed. An improved spectrum sharing algorithm based on the combination of the feedback control information and the optimization algorithm is proposed. The relaxation method is used to achieve the approximate spectrum sharing model, and the spectrum sharing strategy that satisfies the individual outage probability constraints can be obtained iteratively with the observed outage probability. Simulation results show that the proposed spectrum sharing algorithm can achieve the spectrum sharing strategy that satisfies the outage probability constraints and reduce the average outage probability without causing maximum transmission rate reduction of the secondary user.
基金Foundation item： Projects（61102106, 61102105） supported by the National Natural Science Foundation of China Project（2013M530148） supported by China Postdoctoral Science Foundation Project（HEUCF120806） supported by the Fundamental Research Funds for the Central Universities of China
文摘In order to solve discrete multi-objective optimization problems, a non-dominated sorting quantum particle swarm optimization (NSQPSO) based on non-dominated sorting and quantum particle swarm optimization is proposed, and the performance of the NSQPSO is evaluated through five classical benchmark functions. The quantum particle swarm optimization (QPSO) applies the quantum computing theory to particle swarm optimization, and thus has the advantages of both quantum computing theory and particle swarm optimization, so it has a faster convergence rate and a more accurate convergence value. Therefore, QPSO is used as the evolutionary method of the proposed NSQPSO. Also NSQPSO is used to solve cognitive radio spectrum allocation problem. The methods to complete spectrum allocation in previous literature only consider one objective, i.e. network utilization or fairness, but the proposed NSQPSO method, can consider both network utilization and fairness simultaneously through obtaining Pareto front solutions. Cognitive radio systems can select one solution from the Pareto front solutions according to the weight of network reward and fairness. If one weight is unit and the other is zero, then it becomes single objective optimization, so the proposed NSQPSO method has a much wider application range. The experimental research results show that the NSQPS can obtain the same non-dominated solutions as exhaustive search but takes much less time in small dimensions; while in large dimensions, where the problem cannot be solved by exhaustive search, the NSQPSO can still solve the problem, which proves the effectiveness of NSQPSO.
基金supported by the National Natural Science Foundation of China(61305133)the Aeronautical Science Foundation of China grant number 2020Z023053002.
文摘The status of an operator’s situation awareness is one of the critical factors that influence the quality of the missions.Thus the measurement method of the situation awareness status is an important topic to research.So far,there are lots of methods designed for the measurement of situation awareness status,but there is no model that can measure it accurately in real-time,so this work is conducted to deal with such a gap.Firstly,collect the relevant physiological data of operators while they are performing a specific mission,simultaneously,measure their status of situation awareness by using the situation awareness global assessment technique(SAGAT),which is known for accuracy but cannot be used in real-time.And then,after the preprocessing of the raw data,use the physiological data as features,the SAGAT’s results as a label to train a fuzzy cognitive map(FCM),which is an explainable and powerful intelligent model.Also,a hybrid learning algorithm of particle swarm optimization(PSO)and gradient descent is proposed for the FCM training.The final results show that the learned FCM can assess the status of situation awareness accurately in real-time,and the proposed hybrid learning algorithm has better efficiency and accuracy.
基金Projects(61362018,61861019)supported by the National Natural Science Foundation of ChinaProject(1402041B)supported by the Jiangsu Province Postdoctoral Scientific Research Project,China+1 种基金Project(16A174)supported by the Scientific Research Fund of Hunan Provincial Education Department,ChinaProject([2016]283)supported by the Research Study and Innovative Experiment Project of College Students,China
文摘In this paper,a blind multiband spectrum sensing(BMSS)method requiring no knowledge of noise power,primary signal and wireless channel is proposed based on the K-means clustering(KMC).In this approach,the KMC algorithm is used to identify the occupied subband set(OSS)and the idle subband set(ISS),and then the location and number information of the occupied channels are obtained according to the elements in the OSS.Compared with the classical BMSS methods based on the information theoretic criteria(ITC),the new method shows more excellent performance especially in the low signal-to-noise ratio(SNR)and the small sampling number scenarios,and more robust detection performance in noise uncertainty or unequal noise variance applications.Meanwhile,the new method performs more stablely than the ITC-based methods when the occupied subband number increases or the primary signals suffer multi-path fading.Simulation result verifies the effectiveness of the proposed method.
基金supported by the Beijing Natural Science Foundation of China (4102050)
文摘Cognitive radio（CR） technology is considered to be an effective solution to allocate spectrum resources,whereas the primary users of a network do not fully utilize available frequency bands.Spectrum auction framework has been recognized as an effective way to achieve dynamic spectrum access.From the perspective of spectrum auction,multi-band multi-user auction provides a new challenge for spectrum management.This paper proposes an auction framework based on location information for multi-band multi-user spectrum allocation.The performance of the proposed framework is compared with that of traditional auction framework based on a binary interference model as a benchmark.Simulation results show that primary users will obtain more total system revenue by selling their idle frequency bands to secondary users and the spectrum utilization of the proposed framework is more effective and fairer.
基金Project(61471194)supported by the National Natural Science Foundation of ChinaProject(BK20140828)supported by the Natural Science Foundation of Jiangsu Province,ChinaProjects(NS2015088,DUT16RC(3)045)supported by the Fundamental Research Funds for the Central Universities,China
文摘In cognitive radio network(CRN), a secondary user(SU) may utilize the spectrum resource of the primary user(PU) and avoid causing harmful interference to the primary network(PN) via spectrum sensing. In the traditional time spectrum sensing, the SU cannot detect the PU's presence during its transmission, thus increasing interference to the PN. In this work, a novel weighed cooperative bandwidth spectrum sensing method is proposed, which allows multiple SUs to use part of the bandwidth to perform cooperative spectrum sensing throughout the whole frame in order to detect the PU's reappearance in time. The SU's spectrum efficiency is maximized by jointly optimizing sensing bandwidth proportion, number of cooperative SUs and detection probability, subject to the constraints on the SU's interference and the false alarm probability. Simulation results show significant decrease on the interference and improvement on the spectrum efficiency using the proposed weighed cooperative bandwidth spectrum sensing method.
基金supported by the Key International Cooperation Research Project(61720106003)the National Natural Science Foundation of China(62001517)+2 种基金the Shanghai Aerospace Science and Technology Innovation Foundation(SAST2019-095)the NUPTSF(NY220111)the Foundational Research Project of Complex Electronic System Simulation Laboratory(DXZT-JC-ZZ-2019-009,DXZTJC-ZZ-2019-005).
文摘A multi-objective optimization based robust beamforming(BF)scheme is proposed to realize secure transmission in a cognitive satellite and unmanned aerial vehicle(UAV)network.Since the satellite network coexists with the UAV network,we first consider both achievable secrecy rate maximization and total transmit power minimization,and formulate a multi-objective optimization problem(MOOP)using the weighted Tchebycheff approach.Then,by supposing that only imperfect channel state information based on the angular information is available,we propose a method combining angular discretization with Taylor approximation to transform the non-convex objective function and constraints to the convex ones.Next,we adopt semi-definite programming together with randomization technology to solve the original MOOP and obtain the BF weight vector.Finally,simulation results illustrate that the Pareto optimal trade-off can be achieved,and the superiority of our proposed scheme is confirmed by comparing with the existing BF schemes.
文摘Interference suppression is a challenge for radar researchers, especially when mainlobe and sidelobe interference coexist. We present a comprehensive anti-interference approach based on a cognitive bistatic airborne radar. The risk of interception is reduced by lowering the launch energy of the radar transmitting terminal in the direction of interference;main lobe and sidelobe interferences are suppressed via cooperation between the two radars. The interference received by a single radar is extracted from the overall radar signal using multiple signal classification(MUSIC), and the interference is cross-located using two different azimuthal angles. Neural networks allowing good, non-linear nonparametric approximations are used to predict the location of interference, and this information is then used to preset the transmitting notch antenna to reduce the likelihood of interception. To simultaneously suppress mainlobe and sidelobe interferences, a blocking matrix is used to mask mainlobe interference based on azimuthal information, and an adaptive process is used to suppress sidelobe interference. Mainlobe interference is eliminated using the data received by the two radars. Simulation verifies the performance of the model.
基金supported by the Program of the Aeronautical Science Foundation of China(2013ZC15003)
文摘This paper investigates the jamming sensing performance of the simultaneous transmit and receive based cognitive anti-jamming(SCAJ) receiver impaired by phase noise in local oscillators(LO) over fading channels. Firstly, energy detection(ED)based on the jamming to noise ratio(JNR) of the high frequency bands SCAJ receiver with phase noise under different channels is analyzed. Then, the probabilities of jamming detection and false alarm in closed-form for the SCAJ receiver are derived. Finally,the modified Bayesian Cramer-Rao bound(BCRB) of jamming sensing for the SCAJ receiver is presented. Simulation results show that the performance degradation of the SCAJ system due to phase noise is more severe than that due to the channel fading in the circumstances where the signal bandwidth(BW) is kept a constant. Moreover, the signal BW has an effect on the phase noise in LO, and the jamming detection probability of the wideband SCAJ receiver with lower phase noise outperforms that of the narrowband receiver using the same center frequency. Furthermore,an accurate phase noise estimation and compensation scheme can improve the jamming detection capability of the SCAJ receiver in high frequency bands and approach to the upper bound.
基金supported by the National Natural Science Foundation of China(61571149)the Special China Postdoctoral Science Foundation(2015T80325)+2 种基金the Heilongjiang Postdoctoral Fund(LBH-Z13054)the China Scholarship Council and the Fundamental Research Funds for the Central Universities(HEUCFP201772HEUCF160808)
文摘For acquiring high energy efficiency and the maximal throughput, a new time slot structure is designed for energy harvesting(EH) cognitive radio(CR). Considering the CR system with EH and cooperative relay, a best cooperative mechanism(BCM)is proposed for CR with EH. To get the optimal estimation performance, a quantum fireworks algorithm(QFA) is designed to resolve the difficulties of maximal throughput and EH, and the proposed cooperative mechanism is called as QFA-BCM. The proposed QFA combines the advantages of quantum computation theory with the fireworks algorithm(FA). Thus the QFA is able to obtain the optimal solution and its convergence performance is proved. By using the new cooperation mechanism and computing algorithm, the proposed QFA-BCM method can achieve comparable maximal throughput in the new timeslot structure. Simulation results have proved that the QFA-BCM method is superior to previous non-cooperative and cooperative mechanisms.
基金supported by the National Natural Science Foundation of China(60874068).
文摘An approach for modeling a human cognitive framework in time-stressed decision making is presented. The recognitive and metacognitive processes that represent the cognitive framework are modeled by the colored Petri nets （CPNs）. A structural and behavioral analysis method is adopted to obtain the static and dynamic property used to verify the CPNs model of the cognitive framework. Finally, an example from the command and control radar recognition system is used to evaluate the feasibility and availability of the CPNs model adopted in practical systems.
基金supported by the National Natural Science Foundation of China(61471391)the China Postdoctoral Science Foundation(2013M542541)
文摘Based on the cognitive radar concept and the basic connotation of cognitive skywave over-the-horizon radar（SWOTHR）, the system structure and information processingmechanism about cognitive SWOTHR are researched. Amongthem, the hybrid network system architecture which is thedistributed configuration combining with the centralized cognition and its soft/hardware framework with the sense-detectionintegration are proposed, and the information processing framebased on the lens principle and its information processing flowwith receive-transmit joint adaption are designed, which buildand parse the work law for cognition and its self feedback adjustment with the lens focus model and five stages informationprocessing sequence. After that, the system simulation andthe performance analysis and comparison are provided, whichinitially proves the rationality and advantages of the proposedideas. Finally, four important development ideas of futureSWOTHR toward ＂high frequency intelligence information processing system＂ are discussed, which are scene information fusion, dynamic reconfigurable system, hierarchical and modulardesign, and sustainable development. Then the conclusion thatthe cognitive SWOTHR can cause the performance improvement is gotten.
