The latent membrane protein(LMP1)encoded by EBV is expressed in the majority of EBV-associated human malignancies,suggesting it is one of the major oncogenic factors in EBV-mediated carcinogenesis.In the previous stud...The latent membrane protein(LMP1)encoded by EBV is expressed in the majority of EBV-associated human malignancies,suggesting it is one of the major oncogenic factors in EBV-mediated carcinogenesis.In the previous studies we experimentally demonstrated that the DNAzymes targeting LMP1 could specifically down-regulate the expression of LMP1,leading to an increased radiosensitivity both in cells and in展开更多
文摘The latent membrane protein(LMP1)encoded by EBV is expressed in the majority of EBV-associated human malignancies,suggesting it is one of the major oncogenic factors in EBV-mediated carcinogenesis.In the previous studies we experimentally demonstrated that the DNAzymes targeting LMP1 could specifically down-regulate the expression of LMP1,leading to an increased radiosensitivity both in cells and in
