Down-regulation of EBV-LMP1 radio-sensitizes nasopharyngeal carcinoma via NF-κB regulated ATM expression
Down-regulation of EBV-LMP1 radio-sensitizes nasopharyngeal carcinoma via NF-κB regulated ATM expression
摘要
The latent membrane protein(LMP1)encoded by EBV is expressed in the majority of EBV-associated human malignancies,suggesting it is one of the major oncogenic factors in EBV-mediated carcinogenesis.In the previous studies we experimentally demonstrated that the DNAzymes targeting LMP1 could specifically down-regulate the expression of LMP1,leading to an increased radiosensitivity both in cells and in
作者
MA Xiao-qian,YANG Li-fang,XIAO Lan-bo,TANG Min,DENG Meng-yao,LI Zi-jian,SUN Lun-quan,CAO Ya(Cancer Research Institute,Xiangya School of Medicine,Central South University,Changsha 410078,China)
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2010年第A10期2006-2006,共1页
Chinese Journal of Pathophysiology
-
1齐宗利,赵彤,周新华,韩西群,黄宏宇,柳刚,朱梅刚.免疫组化、原位杂交及PCR法检测霍奇金淋巴瘤石蜡组织中EB病毒[J].中华血液学杂志,2003,24(4):203-204. 被引量：7
-
2王艳,王晓枚,成志强,王鹰,刘汉勇,余树林,沈丽红,赵利容.鼻咽癌患者外周血及肿瘤原发部位的病毒检测及意义[J].国际肿瘤学杂志,2014,41(5):393-395. 被引量：3
-
3李燕飞,梅玉屏,朱卫平.RNA干扰LMP1阻滞淋巴瘤细胞于G0/G1期并提高细胞对顺铂的敏感性[J].热带医学杂志,2009,9(9):988-990.
-
4王燕,陈莉.LMP-1、NET-1、VEGF在非角化性鼻咽癌中的表达及其临床意义[J].中国肿瘤生物治疗杂志,2008,15(6):575-580. 被引量：1
-
5韩纪良,徐勤.鼻咽癌侵袭和转移相关分子标志物研究进展[J].中文科技期刊数据库(文摘版)医药卫生,2016(3):00277-00278.
-
6袁轶群,孙振柱.霍奇金淋巴瘤与EB病毒感染的相关性研究[J].农垦医学,2011,33(5):434-437. 被引量：1
-
7饶慧兰,侯景辉,黄奕莉,郝亚萍,张惠忠,邵建永,林汉良.涎腺恶性淋巴上皮病变临床病理特征及其与EB病毒的相关性[J].癌症,2001,20(3):270-273. 被引量：2
-
8吴名耀,梁英锐,吴贤英.EXPRESSION OF EBV LATENT MEMBRANE PROTEIN IN ESOPHAGEAL CARCINOMA AND PARA-CANCEROUS MUCOSA[J].Chinese Journal of Cancer Research,1997,9(3):78-79.
-
9明萌,王大斌,易建华,邹典定,姚俊霞.Survivin在中线T细胞淋巴瘤中的表达及其与EB病毒感染的关系[J].中国实验血液学杂志,2005,13(5):815-818. 被引量：2
-
10姚运红,孙宁,唐慰萍,李飞虹.鼻咽癌中EB病毒的原位杂交检测[J].广东医学院学报,1998,16(1):10-11.
