目的 探讨结合DTI的短回波反转恢复各向同性变换角度RF激发3DT2TSE序列（SPACE：Sampling Perfection with Application optimized Contrasts using different flip angle evolutions）在腰骶丛病变成像中的应用价值。方法10例健康志愿...目的 探讨结合DTI的短回波反转恢复各向同性变换角度RF激发3DT2TSE序列（SPACE：Sampling Perfection with Application optimized Contrasts using different flip angle evolutions）在腰骶丛病变成像中的应用价值。方法10例健康志愿者和32例腰骶丛神经病变患者行常规扫描序列、3DSPACE STIR序列和DTI序列扫描。结果 10名健康自愿者,L1~S1腰骶神经根3DSPCACE STIR序列均得到清晰显示。32例腰骶丛神经病变中,神经根受推压移位27例,受侵犯5例。椎间盘突出所致神经根受损的FA值降低（P〈0.05）,而ADC值升高（P〈0.05）。结论 3DSPACE STIR序列具有较好的组织对比,图像可被作为测量DTI数据的FA值及ADC值的高分辨率蒙片,两者结合可以很好评估腰骶神经丛的神经压迫位置和神经受侵犯的范围和程度。展开更多
目的:用弥散张量成像(DTI)和P300技术评价通督调神针刺法对非痴呆性血管性认知功能障碍(vascular cognitive impairment with no dementia,VCIND)的治疗作用,为临床治疗提供借鉴。方法:将40例VCIND患者随机分为治疗组20例和对照组20例...目的:用弥散张量成像(DTI)和P300技术评价通督调神针刺法对非痴呆性血管性认知功能障碍(vascular cognitive impairment with no dementia,VCIND)的治疗作用,为临床治疗提供借鉴。方法:将40例VCIND患者随机分为治疗组20例和对照组20例。对照组予口服尼莫地平片,治疗组予通督调神针刺治疗,观察两组患者治疗前和治疗8周后的量表评分、事件相关电位P300潜伏期、弥散张量成像(DTI技术)FA值、ADC值的变化。结果:治疗后治疗组数值改变程度明显大于对照组,差值有统计学意义(P<0.05)。组间有效率有显著差异性(P<0.05)。结论:通督调神针刺法对VCIND患者认知功能的改善,疗效明显优于单纯西药组,值得临床推广及运用。展开更多
To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, a modified algorithm is proposed for calculating these parameters. Magnetic resonance （MR） diffusion tensor images...To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, a modified algorithm is proposed for calculating these parameters. Magnetic resonance （MR） diffusion tensor images of five healthy volunteers are collected. The diffusion sensitive gradient magnetic fields are applied along 25 directions and the diffusion weighting value is 1 000 s/mm^2. Many positive-indefinite diffusion tensors can be found in the white matter area, such as the genu and the splenium of corpus callosum. Due to the positive-indefinite matrix, the mean diffusivity （MD） and the fractional anisotropy （FA） are under-estimated and over-estimated by using the conventional algorithm. Thus, the conventional algorithm is modified by using the absolute values of all eigenvalues. Results show that both the robustness and the reliability for deriving these parameters are improved by the modified algorithm.展开更多
文摘目的:用弥散张量成像(DTI)和P300技术评价通督调神针刺法对非痴呆性血管性认知功能障碍(vascular cognitive impairment with no dementia,VCIND)的治疗作用,为临床治疗提供借鉴。方法:将40例VCIND患者随机分为治疗组20例和对照组20例。对照组予口服尼莫地平片,治疗组予通督调神针刺治疗,观察两组患者治疗前和治疗8周后的量表评分、事件相关电位P300潜伏期、弥散张量成像(DTI技术)FA值、ADC值的变化。结果:治疗后治疗组数值改变程度明显大于对照组,差值有统计学意义(P<0.05)。组间有效率有显著差异性(P<0.05)。结论:通督调神针刺法对VCIND患者认知功能的改善,疗效明显优于单纯西药组,值得临床推广及运用。
基金Supported by the Research Project of Dongguan Higher Education (200910815252)the Beijing Natural Science Foundation(7102102)the Scientific Research Key Program of Beijing Municipal Commission of Ed-ucation(KZ200810025011)~~
文摘To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, a modified algorithm is proposed for calculating these parameters. Magnetic resonance （MR） diffusion tensor images of five healthy volunteers are collected. The diffusion sensitive gradient magnetic fields are applied along 25 directions and the diffusion weighting value is 1 000 s/mm^2. Many positive-indefinite diffusion tensors can be found in the white matter area, such as the genu and the splenium of corpus callosum. Due to the positive-indefinite matrix, the mean diffusivity （MD） and the fractional anisotropy （FA） are under-estimated and over-estimated by using the conventional algorithm. Thus, the conventional algorithm is modified by using the absolute values of all eigenvalues. Results show that both the robustness and the reliability for deriving these parameters are improved by the modified algorithm.
