The synthesis of a new reagent 1-azobenzene-3-(5-nitro-2-pyridyl)-triazene(ABNPDT) and its colour reaction with cadimum were reported. At pH=10.40, in the presence of Triton X-100, ABNPDT react with cadimum to form a ...The synthesis of a new reagent 1-azobenzene-3-(5-nitro-2-pyridyl)-triazene(ABNPDT) and its colour reaction with cadimum were reported. At pH=10.40, in the presence of Triton X-100, ABNPDT react with cadimum to form a red Complex. The maximum absorption of reagent and complex are at 430nm and 520NM respectively. The molar absorpitivity is 2.0710 5L·mol -1 ·cm -1 . Berr’s law can be applied in the rang of 0～12μg/25ml. This method was used to determine tarce cadmium in water with satisfactory results.展开更多
In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxi...In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxic Alternaric acid structure. The results displayed the information on modification of primary molecules and further synthesis of new bioactive compounds.展开更多
The first total synthesis of （+）-5α-hydroxy-isopterocarpolone （1）, an oxygenated eudesmane isolated from Chinese folk medicine Artemisia eriopoda, starting from （+）-dihydrocarvone（2） was described. Compound 4...The first total synthesis of （+）-5α-hydroxy-isopterocarpolone （1）, an oxygenated eudesmane isolated from Chinese folk medicine Artemisia eriopoda, starting from （+）-dihydrocarvone（2） was described. Compound 4 was stereoselectively prepared from compound 2 in three steps according to reference-. The treatment of tosylhydrazone 5, which was formed via the reaction of compound 4 and TsNHNH2 catalyzed by BF3-5Et2O, with an excess of n-butyllithium gave triene 6. Oxidation of triene 6 with singlet oxygen afforded the desired endo-peroxide 7 as a single product. Reductive cleavage of peroxide 7 with K2CO3 gave α-rotunol 3, a natural eudesmane firstly isolated in 1969. Hydrolysis of α-rotunol 3 with 10% sulfuric acid afforded （+）-5α-hydroxy-isopterocarpolone （1）. The structures of all the compounds were confirmed by IR, MS and NMR spectra.展开更多
文摘The synthesis of a new reagent 1-azobenzene-3-(5-nitro-2-pyridyl)-triazene(ABNPDT) and its colour reaction with cadimum were reported. At pH=10.40, in the presence of Triton X-100, ABNPDT react with cadimum to form a red Complex. The maximum absorption of reagent and complex are at 430nm and 520NM respectively. The molar absorpitivity is 2.0710 5L·mol -1 ·cm -1 . Berr’s law can be applied in the rang of 0～12μg/25ml. This method was used to determine tarce cadmium in water with satisfactory results.
文摘In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxic Alternaric acid structure. The results displayed the information on modification of primary molecules and further synthesis of new bioactive compounds.
文摘The first total synthesis of （+）-5α-hydroxy-isopterocarpolone （1）, an oxygenated eudesmane isolated from Chinese folk medicine Artemisia eriopoda, starting from （+）-dihydrocarvone（2） was described. Compound 4 was stereoselectively prepared from compound 2 in three steps according to reference-. The treatment of tosylhydrazone 5, which was formed via the reaction of compound 4 and TsNHNH2 catalyzed by BF3-5Et2O, with an excess of n-butyllithium gave triene 6. Oxidation of triene 6 with singlet oxygen afforded the desired endo-peroxide 7 as a single product. Reductive cleavage of peroxide 7 with K2CO3 gave α-rotunol 3, a natural eudesmane firstly isolated in 1969. Hydrolysis of α-rotunol 3 with 10% sulfuric acid afforded （+）-5α-hydroxy-isopterocarpolone （1）. The structures of all the compounds were confirmed by IR, MS and NMR spectra.
