In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the ...In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%.展开更多
In order to study the distribution of shale gas reservoir in the Babaoshan Basin of Eastern Kunlun,the wide-field electromagnetic(WFEM)survey was carried out to obtain the spatial distribution characteristics of the u...In order to study the distribution of shale gas reservoir in the Babaoshan Basin of Eastern Kunlun,the wide-field electromagnetic(WFEM)survey was carried out to obtain the spatial distribution characteristics of the underground electrical volume resistivity based on the delineation of the scope of the Babaoshan Basin by regional gravity data.The basic characteristics of the basement,basin framework,and extension,vertical change,burial depth of dark mud shale in this area were identified,and the electrical distribution of the Babaoshan mud shale horizon was revealed,which has been proved to be a good geological effect by drilling.The exploration results show that the WFEM has significant effects on the exploration of shale gas occurrence strata,which meets the needs of investigation and evaluation of multi-layered and large-scale shale gas,and plays a good demonstration role in the follow-up shale gas exploration.展开更多
A modeling tool for simulating three-dimensional land frequency-domain controlled-source electromagnetic surveys,based on a finite-element discretization of the Helmholtz equation for the electric fields,has been deve...A modeling tool for simulating three-dimensional land frequency-domain controlled-source electromagnetic surveys,based on a finite-element discretization of the Helmholtz equation for the electric fields,has been developed.The main difference between our modeling method and those previous works is edge finite-element approach applied to solving the three-dimensional land frequency-domain electromagnetic responses generated by horizontal electric dipole source.Firstly,the edge finite-element equation is formulated through the Galerkin method based on Helmholtz equation of the electric fields.Secondly,in order to check the validity of the modeling code,the numerical results are compared with the analytical solutions for a homogeneous half-space model.Finally,other three models are simulated with three-dimensional electromagnetic responses.The results indicate that the method can be applied for solving three-dimensional electromagnetic responses.The algorithm has been demonstrated,which can be effective to modeling the complex geo-electrical structures.This efficient algorithm will help to study the distribution laws of3-D land frequency-domain controlled-source electromagnetic responses and to setup basis for research of three-dimensional inversion.展开更多
Airborne electromagnetic transient method enjoys the advantages of high-efficiency and the high resolution of electromagnetic anomalies,especially suitable for mining detection around goaf areas and deep exploration o...Airborne electromagnetic transient method enjoys the advantages of high-efficiency and the high resolution of electromagnetic anomalies,especially suitable for mining detection around goaf areas and deep exploration of minerals.In this paper,we calculated the full-wave airborne transient electromagnetic data,according to the result of numerical research,the advantage of switch-off time response in electromagnetic detection was proofed via experiments.Firstly,based on the full-wave airborne transient electromagnetic system developed by Jilin University(JLU-ATEMI),we proposed a method to compute the full-waveform electromagnetic(EM)data of 3D model using the FDTD approach and convolution algorithm,and verify the calculation by the response of homogenous half-space.Then,through comparison of switch-off-time response and off-time response,we studied the effect of ramp time on anomaly detection.Finally,we arranged two experimental electromagnetic detection,the results indicated that the switch-off-time response can reveal the shallow target more effectively,and the full-waveform airborne electromagnetic system is an effective technique for shallow target detection.展开更多
In large loop transient electromagnetic method(TEM),the late time apparent resistivity formula cannot truly reflect the geoelectric model,thus it needs to define the all-time apparent resistivity with the position inf...In large loop transient electromagnetic method(TEM),the late time apparent resistivity formula cannot truly reflect the geoelectric model,thus it needs to define the all-time apparent resistivity with the position information of measuring point.Utilizing very fast simulated annealing(VFSA) to fit the theoretical electromagnetic force(EMF) and measured EMF could obtain the all-time apparent resistivity of the measuring points in rectangular transmitting loop.The selective cope of initial model of VFSA could be confirmed by taking the late time apparent resistivity of transient electromagnetic method as the prior information.For verifying the correctness,the all-time apparent resistivities of the geoelectric models were calculated by VFSA and dichotomy,respectively.The results indicate that the relative differences of apparent resistivities calculated by these two methods are within 3%.The change of measuring point position has little influence on the tracing pattern of all-time apparent resistivity.The first branch of the curve of all-time apparent resistivity is close to the resistivity of the first layer medium and the last branch is close to the resistivity of the last layer medium,which proves the correctness of the arithmetics proposed.展开更多
The wide-field electromagnetic method is widely used in hydrocarbon exploration,mineral deposit detection,and geological disaster prediction.However,apparent resistivity and normalized field amplitude exceeding 2048 H...The wide-field electromagnetic method is widely used in hydrocarbon exploration,mineral deposit detection,and geological disaster prediction.However,apparent resistivity and normalized field amplitude exceeding 2048 Hz often exhibit upward warping in data,making geophysical inversion and interpretation challenging.The cumulative error of the crystal oscillator in signal transmission and acquisition contributes to an upturned apparent resistivity curve.To address this,a high-frequency information extraction method is proposed based on time-domain signal reconstruction,which helps to record a complete current data sequence;moreover,it helps estimate the crystal oscillator error for the transmitted signal.Considering the recorded error,a received signal was corrected using a set of reconstruction algorithms.After processing,the high-frequency component of the wide-field electromagnetic data was not upturned,while accurate high-frequency information was extracted from the signal.Therefore,the proposed method helped effectively extract high-frequency components of all wide-field electromagnetic data.展开更多
A fixed artificial source(greater than 200 kW) was used and the source location was selected at a high resistivity region to ensure high emission efficiency. Some publications used the "earth-ionosphere" mod...A fixed artificial source(greater than 200 kW) was used and the source location was selected at a high resistivity region to ensure high emission efficiency. Some publications used the "earth-ionosphere" mode in modeling the electromagnetic(EM) fields with the offset up to a thousand kilometer, and such EM fields still have a signal/noise ratio of 10-20 dB. This means that a new EM method with fixed source is feasible, but in their calculation, the displacement in air was neglected. In this work, some three-layer modeling results were presented to illustrate the basic EM fields' characteristics in the near, far and waveguide areas under "earth-ionosphere" mode, and a standard is given to distinguish the boundary of near, far and waveguide areas. Due to the influence of the ionosphere and displacement current in the air, the "earth-ionosphere" mode EM fields have an extra waveguide zone, where the fields' behavior is very different from that of the far field zone.展开更多
The construction of waste rock dumps on existing tailing ponds has been put into practice in China to save precious land resources. This work focuses on the safety assessment of the Daheishan molybdenum mine waste roc...The construction of waste rock dumps on existing tailing ponds has been put into practice in China to save precious land resources. This work focuses on the safety assessment of the Daheishan molybdenum mine waste rock dump under construction on two adjoining tailings ponds. The consolidation of the tailings foundation and the filling quality of the waste rock are investigated by the transient electromagnetic method through detecting water-rich areas and loose packing areas, from which, the depth of phreatic line is also estimated. With such information and the material parameters, the numerical method based on shear strength reduction is applied to analyzing the overall stability of the waste rock dump and the tailings ponds over a number of typical cross sections under both current and designed conditions, where the complex geological profiles exposed by site investigation are considered. Through numerical experiments, the influence of soft lenses in the tailings and possible loose packing areas in the waste rock is examined. Although large displacements may develop due to the soft tailings foundation, the results show that the waste rock dump satisfies the safety requirements under both present and designed conditions.展开更多
In the view of the disadvantages of complex method (CM) and electromagnetism-like algorithm (EM), complex electromagnetism-like hybrid algorithm (CEM) was proposed by embedding complex method into electromagnetism-lik...In the view of the disadvantages of complex method (CM) and electromagnetism-like algorithm (EM), complex electromagnetism-like hybrid algorithm (CEM) was proposed by embedding complex method into electromagnetism-like algorithm as local optimization algorithm. CEM was adopted to search the minimum safety factor in slope stability analysis and the results show that CEM holds advantages over EM and CM. It combines the merits of two and is more stable and efficient. For further improvement, two CEM hybrid algorithms based on predatory search (PS) strategies were proposed, both of which consist of modified algorithms and the search area of which is dynamically adjusted by changing restriction. The CEM-PS1 adopts theoretical framework of original predatory search strategy. The CEM-PS2 employs the idea of area-restricted search learned from predatory search strategy, but the algorithm structure is simpler. Both the CEM-PS1 and CEM-PS2 have been demonstrated more effective and efficient than the others. As for complex method which locates in hybrid algorithm, the optimization can be achieved at a convergence precision of 1×10-3, which is recommended to use.展开更多
A finite element algorithm combined with divergence condition was presented for computing three-dimensional(3D) magnetotelluric forward modeling. The finite element equation of three-dimensional magnetotelluric forwar...A finite element algorithm combined with divergence condition was presented for computing three-dimensional(3D) magnetotelluric forward modeling. The finite element equation of three-dimensional magnetotelluric forward modeling was derived from Maxwell's equations using general variation principle. The divergence condition was added forcedly to the electric field boundary value problem, which made the solution correct. The system of equation of the finite element algorithm was a large sparse, banded, symmetric, ill-conditioned, non-Hermitian complex matrix equation, which can be solved using the Bi-CGSTAB method. In order to prove correctness of the three-dimensional magnetotelluric forward algorithm, the computed results and analytic results of one-dimensional geo-electrical model were compared. In addition, the three-dimensional magnetotelluric forward algorithm is given a further evaluation by computing COMMEMI model. The forward modeling results show that the algorithm is very efficient, and it has a lot of advantages, such as the high precision, the canonical process of solving problem, meeting the internal boundary condition automatically and adapting to all kinds of distribution of multi-substances.展开更多
Permanent magnet tubular linear motors(TLMs) arranged in multiple rows and multiple columns used for a radiotherapy machine were studied. Due to severe volumetric and thermal constraints, the TLMs were at high risk of...Permanent magnet tubular linear motors(TLMs) arranged in multiple rows and multiple columns used for a radiotherapy machine were studied. Due to severe volumetric and thermal constraints, the TLMs were at high risk of overheating. To predict the performance of the TLMs accurately, a multi-physics analysis approach was proposed. Specifically, it considered the coupling effects amongst the electromagnetic and the thermal models of the TLMs, as well as the fluid model of the surrounding air. To reduce computation cost, both the electromagnetic and the thermal models were based on lumped-parameter methods. Only a minimum set of numerical computation(computational fluid dynamics, CFD) was performed to model the complex fluid behavior. With the proposed approach, both steady state and transient state temperature distributions, thermal rating and permissible load can be predicted. The validity of this approach is verified through the experiment.展开更多
To evaluate the feasibility of using magnetic iron oxide nanoparticle as wild PTEN gene carrier for transfection in vitro to reverse cisplatin-resistance of A549/CDDP cells, A549/CDDP cells were transfected with the w...To evaluate the feasibility of using magnetic iron oxide nanoparticle as wild PTEN gene carrier for transfection in vitro to reverse cisplatin-resistance of A549/CDDP cells, A549/CDDP cells were transfected with the wild PTEN gene expression plasmid (pGFP-PTEN) by magnetic iron nanoparticle and lipo2000. The transfection efficiency was detected by fluorescence microscope and flow cytometer. The expression levels of PTEN mRNA and protein were detected by reverse transcription polymerase chain reaction (RT-PCR) and immunocytochemistry analysis. The effect of PTEN transfection on cell cycle enhances the sensitivity of A549/CDDP to cisplatin and nanoparticle-mediated transfection has a higher efficiency than that of the liposome-mediated group. The apoptosis level was up-regulated in PTEN transfection group. The magnetic iron oxide nanoparticle could be used as one of the ideal gene carriers for PTEN gene delivery in vitro. PTEN can be an effective target for reversing cisplatin-resistance in lung cancer.展开更多
A simple and rapid strategy to construct laccase biosensor for determination of catechol was investigated. Magnetic multiwalled carbon nanotubes (MMCNT) which possess excellent capability of electron transfer were pre...A simple and rapid strategy to construct laccase biosensor for determination of catechol was investigated. Magnetic multiwalled carbon nanotubes (MMCNT) which possess excellent capability of electron transfer were prepared by chemical coprecipitation method. Scanning electron microscope (SEM) and vibrating sample magnetometer (VSM) were used to identify its surfacetopography and magnetization, respectively. Laccase was immobilized on the MMCNT modified magnetic carbon paste electrode by the aid of chitosan/silica (CS) hybrid membrane. Using current-time detection method, the biosensor shows a linear response related to the concentration of catechol in the range from 10-7 to 0.165×10-3 mol/L. The corresponding detection limit is 3.34×10-8 mol/L based on signal-to-noise ratios (S/N) ≥3 under the optimized conditions. In addition, its response current retains 90% of the original after being stored for 45 d. The results indicate that this proposed strategy can be expected to develop other enzyme-based biosensors.展开更多
The vector control algorithm based on vector space decomposition （VSD） transformation method has a more flexible control freedom, which can control the fundamental and harmonic subspace separately. To this end, a cu...The vector control algorithm based on vector space decomposition （VSD） transformation method has a more flexible control freedom, which can control the fundamental and harmonic subspace separately. To this end, a current vector decoupling control algorithm for six-phase permanent magnet synchronous motor （PMSM） is designed. Using the proposed synchronous rotating coordinate transformation matrix, the fundamental and harmonic components in d-q subspace are changed into direct current （DC） component, only using the traditional proportional integral （PI） controller can meet the non-static difference adjustment, and the controller parameter design method is given by employing intemal model principle. In addition, in order to remove the 5th and 7th harmonic components of stator current, the current PI controller parallel with resonant controller is employed in x-y subspace to realize the specific harmonic component compensation. Simulation results verify the effectiveness of current decoupling vector controller.展开更多
基金Supported by the Beijing Municipal Science&Technology Commission(Z211100004421012),the Key Reaserch and Development Pro⁃gram of China(2022YFF0605902)。
文摘In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%.
基金Project(2019-SF-141)supported by Science and Technology Program of Qinghai Province,ChinaProjects(2017042105kc055,2017042014ky014)supported by Geological Exploration Foundation of Qinghai Province,China。
文摘In order to study the distribution of shale gas reservoir in the Babaoshan Basin of Eastern Kunlun,the wide-field electromagnetic(WFEM)survey was carried out to obtain the spatial distribution characteristics of the underground electrical volume resistivity based on the delineation of the scope of the Babaoshan Basin by regional gravity data.The basic characteristics of the basement,basin framework,and extension,vertical change,burial depth of dark mud shale in this area were identified,and the electrical distribution of the Babaoshan mud shale horizon was revealed,which has been proved to be a good geological effect by drilling.The exploration results show that the WFEM has significant effects on the exploration of shale gas occurrence strata,which meets the needs of investigation and evaluation of multi-layered and large-scale shale gas,and plays a good demonstration role in the follow-up shale gas exploration.
基金Projects(41674080,41674079)supported by the National Natural Science Foundation of China
文摘A modeling tool for simulating three-dimensional land frequency-domain controlled-source electromagnetic surveys,based on a finite-element discretization of the Helmholtz equation for the electric fields,has been developed.The main difference between our modeling method and those previous works is edge finite-element approach applied to solving the three-dimensional land frequency-domain electromagnetic responses generated by horizontal electric dipole source.Firstly,the edge finite-element equation is formulated through the Galerkin method based on Helmholtz equation of the electric fields.Secondly,in order to check the validity of the modeling code,the numerical results are compared with the analytical solutions for a homogeneous half-space model.Finally,other three models are simulated with three-dimensional electromagnetic responses.The results indicate that the method can be applied for solving three-dimensional electromagnetic responses.The algorithm has been demonstrated,which can be effective to modeling the complex geo-electrical structures.This efficient algorithm will help to study the distribution laws of3-D land frequency-domain controlled-source electromagnetic responses and to setup basis for research of three-dimensional inversion.
基金Project(41674109) supported by the National Natural Science Foundation of China
文摘Airborne electromagnetic transient method enjoys the advantages of high-efficiency and the high resolution of electromagnetic anomalies,especially suitable for mining detection around goaf areas and deep exploration of minerals.In this paper,we calculated the full-wave airborne transient electromagnetic data,according to the result of numerical research,the advantage of switch-off time response in electromagnetic detection was proofed via experiments.Firstly,based on the full-wave airborne transient electromagnetic system developed by Jilin University(JLU-ATEMI),we proposed a method to compute the full-waveform electromagnetic(EM)data of 3D model using the FDTD approach and convolution algorithm,and verify the calculation by the response of homogenous half-space.Then,through comparison of switch-off-time response and off-time response,we studied the effect of ramp time on anomaly detection.Finally,we arranged two experimental electromagnetic detection,the results indicated that the switch-off-time response can reveal the shallow target more effectively,and the full-waveform airborne electromagnetic system is an effective technique for shallow target detection.
基金Projects(40804027,41074085) supported by the National Natural Science Foundation of ChinaProject(09JJ3048) supported by the Natural Science Foundation of Hunan Province,ChinaProject(200805331082) supported by the Research Fund for the Doctoral Program of Higher Education,China
文摘In large loop transient electromagnetic method(TEM),the late time apparent resistivity formula cannot truly reflect the geoelectric model,thus it needs to define the all-time apparent resistivity with the position information of measuring point.Utilizing very fast simulated annealing(VFSA) to fit the theoretical electromagnetic force(EMF) and measured EMF could obtain the all-time apparent resistivity of the measuring points in rectangular transmitting loop.The selective cope of initial model of VFSA could be confirmed by taking the late time apparent resistivity of transient electromagnetic method as the prior information.For verifying the correctness,the all-time apparent resistivities of the geoelectric models were calculated by VFSA and dichotomy,respectively.The results indicate that the relative differences of apparent resistivities calculated by these two methods are within 3%.The change of measuring point position has little influence on the tracing pattern of all-time apparent resistivity.The first branch of the curve of all-time apparent resistivity is close to the resistivity of the first layer medium and the last branch is close to the resistivity of the last layer medium,which proves the correctness of the arithmetics proposed.
基金Project(42004056)supported by the National Natural Science Foundation of ChinaProject(ZR2020QD052)supported by the Natural Science Foundation of Shandong Province,ChinaProject(2019YFC0604902)supported by the National Key Research and Development Program of China。
文摘The wide-field electromagnetic method is widely used in hydrocarbon exploration,mineral deposit detection,and geological disaster prediction.However,apparent resistivity and normalized field amplitude exceeding 2048 Hz often exhibit upward warping in data,making geophysical inversion and interpretation challenging.The cumulative error of the crystal oscillator in signal transmission and acquisition contributes to an upturned apparent resistivity curve.To address this,a high-frequency information extraction method is proposed based on time-domain signal reconstruction,which helps to record a complete current data sequence;moreover,it helps estimate the crystal oscillator error for the transmitted signal.Considering the recorded error,a received signal was corrected using a set of reconstruction algorithms.After processing,the high-frequency component of the wide-field electromagnetic data was not upturned,while accurate high-frequency information was extracted from the signal.Therefore,the proposed method helped effectively extract high-frequency components of all wide-field electromagnetic data.
基金Projects(41204054,41541036,41604111)supported by the National Natural Science Foundation of China
文摘A fixed artificial source(greater than 200 kW) was used and the source location was selected at a high resistivity region to ensure high emission efficiency. Some publications used the "earth-ionosphere" mode in modeling the electromagnetic(EM) fields with the offset up to a thousand kilometer, and such EM fields still have a signal/noise ratio of 10-20 dB. This means that a new EM method with fixed source is feasible, but in their calculation, the displacement in air was neglected. In this work, some three-layer modeling results were presented to illustrate the basic EM fields' characteristics in the near, far and waveguide areas under "earth-ionosphere" mode, and a standard is given to distinguish the boundary of near, far and waveguide areas. Due to the influence of the ionosphere and displacement current in the air, the "earth-ionosphere" mode EM fields have an extra waveguide zone, where the fields' behavior is very different from that of the far field zone.
基金Projects(51209118,71373245)supported by the National Natural Science Foundation of ChinaProject(2014JBKY01)supported by the Fundamental Research Funds for CASST,China
文摘The construction of waste rock dumps on existing tailing ponds has been put into practice in China to save precious land resources. This work focuses on the safety assessment of the Daheishan molybdenum mine waste rock dump under construction on two adjoining tailings ponds. The consolidation of the tailings foundation and the filling quality of the waste rock are investigated by the transient electromagnetic method through detecting water-rich areas and loose packing areas, from which, the depth of phreatic line is also estimated. With such information and the material parameters, the numerical method based on shear strength reduction is applied to analyzing the overall stability of the waste rock dump and the tailings ponds over a number of typical cross sections under both current and designed conditions, where the complex geological profiles exposed by site investigation are considered. Through numerical experiments, the influence of soft lenses in the tailings and possible loose packing areas in the waste rock is examined. Although large displacements may develop due to the soft tailings foundation, the results show that the waste rock dump satisfies the safety requirements under both present and designed conditions.
基金Project(10972238) supported by the National Natural Science Foundation of ChinaProject(2010ssxt237) supported by Graduate Student Innovation Foundation of Central South University, ChinaProject supported by Excellent Doctoral Thesis Support Program of Central South University, China
文摘In the view of the disadvantages of complex method (CM) and electromagnetism-like algorithm (EM), complex electromagnetism-like hybrid algorithm (CEM) was proposed by embedding complex method into electromagnetism-like algorithm as local optimization algorithm. CEM was adopted to search the minimum safety factor in slope stability analysis and the results show that CEM holds advantages over EM and CM. It combines the merits of two and is more stable and efficient. For further improvement, two CEM hybrid algorithms based on predatory search (PS) strategies were proposed, both of which consist of modified algorithms and the search area of which is dynamically adjusted by changing restriction. The CEM-PS1 adopts theoretical framework of original predatory search strategy. The CEM-PS2 employs the idea of area-restricted search learned from predatory search strategy, but the algorithm structure is simpler. Both the CEM-PS1 and CEM-PS2 have been demonstrated more effective and efficient than the others. As for complex method which locates in hybrid algorithm, the optimization can be achieved at a convergence precision of 1×10-3, which is recommended to use.
基金Project(60672042) supported by the National Natural Science Foundation of China
文摘A finite element algorithm combined with divergence condition was presented for computing three-dimensional(3D) magnetotelluric forward modeling. The finite element equation of three-dimensional magnetotelluric forward modeling was derived from Maxwell's equations using general variation principle. The divergence condition was added forcedly to the electric field boundary value problem, which made the solution correct. The system of equation of the finite element algorithm was a large sparse, banded, symmetric, ill-conditioned, non-Hermitian complex matrix equation, which can be solved using the Bi-CGSTAB method. In order to prove correctness of the three-dimensional magnetotelluric forward algorithm, the computed results and analytic results of one-dimensional geo-electrical model were compared. In addition, the three-dimensional magnetotelluric forward algorithm is given a further evaluation by computing COMMEMI model. The forward modeling results show that the algorithm is very efficient, and it has a lot of advantages, such as the high precision, the canonical process of solving problem, meeting the internal boundary condition automatically and adapting to all kinds of distribution of multi-substances.
基金Project(2015BAI03B00)supported by the National Key Technology R&D Program of ChinaProject(Z141100000514015)supported by Science and Technology Planning Program of Beijing,ChinaProject(SKLT12A03)supported by Tribology Science Fund of State Key Laboratory of Tribology,China
文摘Permanent magnet tubular linear motors(TLMs) arranged in multiple rows and multiple columns used for a radiotherapy machine were studied. Due to severe volumetric and thermal constraints, the TLMs were at high risk of overheating. To predict the performance of the TLMs accurately, a multi-physics analysis approach was proposed. Specifically, it considered the coupling effects amongst the electromagnetic and the thermal models of the TLMs, as well as the fluid model of the surrounding air. To reduce computation cost, both the electromagnetic and the thermal models were based on lumped-parameter methods. Only a minimum set of numerical computation(computational fluid dynamics, CFD) was performed to model the complex fluid behavior. With the proposed approach, both steady state and transient state temperature distributions, thermal rating and permissible load can be predicted. The validity of this approach is verified through the experiment.
基金Project(07JJ3055)supported by the Natural Science Foundation of Hunan Province,China
文摘To evaluate the feasibility of using magnetic iron oxide nanoparticle as wild PTEN gene carrier for transfection in vitro to reverse cisplatin-resistance of A549/CDDP cells, A549/CDDP cells were transfected with the wild PTEN gene expression plasmid (pGFP-PTEN) by magnetic iron nanoparticle and lipo2000. The transfection efficiency was detected by fluorescence microscope and flow cytometer. The expression levels of PTEN mRNA and protein were detected by reverse transcription polymerase chain reaction (RT-PCR) and immunocytochemistry analysis. The effect of PTEN transfection on cell cycle enhances the sensitivity of A549/CDDP to cisplatin and nanoparticle-mediated transfection has a higher efficiency than that of the liposome-mediated group. The apoptosis level was up-regulated in PTEN transfection group. The magnetic iron oxide nanoparticle could be used as one of the ideal gene carriers for PTEN gene delivery in vitro. PTEN can be an effective target for reversing cisplatin-resistance in lung cancer.
基金Project(IRT0719) supported by the Program for Changjiang Scholars and Innovative Research Team in University, ChinaProjects (50978088, 51039001) supported by the National Natural Science Foundation of China+3 种基金Project(2009FJ1010) supported by the Hunan Key Scientific Research Program, ChinaProject(10JJ7005) supported by the Natural Science Foundation of Hunan Province, ChinaProjects(CX2009B080, CX2010B157) supported by the Hunan Provincial Innovation Foundation For PostgraduateProject supported by the Fundamental Research Funds for the Central Universities, Hunan University, China
文摘A simple and rapid strategy to construct laccase biosensor for determination of catechol was investigated. Magnetic multiwalled carbon nanotubes (MMCNT) which possess excellent capability of electron transfer were prepared by chemical coprecipitation method. Scanning electron microscope (SEM) and vibrating sample magnetometer (VSM) were used to identify its surfacetopography and magnetization, respectively. Laccase was immobilized on the MMCNT modified magnetic carbon paste electrode by the aid of chitosan/silica (CS) hybrid membrane. Using current-time detection method, the biosensor shows a linear response related to the concentration of catechol in the range from 10-7 to 0.165×10-3 mol/L. The corresponding detection limit is 3.34×10-8 mol/L based on signal-to-noise ratios (S/N) ≥3 under the optimized conditions. In addition, its response current retains 90% of the original after being stored for 45 d. The results indicate that this proposed strategy can be expected to develop other enzyme-based biosensors.
基金Project(51507188)supported by the National Natural Science Foundation of China
文摘The vector control algorithm based on vector space decomposition （VSD） transformation method has a more flexible control freedom, which can control the fundamental and harmonic subspace separately. To this end, a current vector decoupling control algorithm for six-phase permanent magnet synchronous motor （PMSM） is designed. Using the proposed synchronous rotating coordinate transformation matrix, the fundamental and harmonic components in d-q subspace are changed into direct current （DC） component, only using the traditional proportional integral （PI） controller can meet the non-static difference adjustment, and the controller parameter design method is given by employing intemal model principle. In addition, in order to remove the 5th and 7th harmonic components of stator current, the current PI controller parallel with resonant controller is employed in x-y subspace to realize the specific harmonic component compensation. Simulation results verify the effectiveness of current decoupling vector controller.
