Brain, spinal cord, lung, heart and liver of mouse infected by VSV was studied using immunohistochemistry method and HE staining. The results showed that VSV can infect mouse, in earlier period of infection, lesions l...Brain, spinal cord, lung, heart and liver of mouse infected by VSV was studied using immunohistochemistry method and HE staining. The results showed that VSV can infect mouse, in earlier period of infection, lesions located mainly in lung, in anaphase of infection, lesions located mainly in brain and spinal cord. Positive cells were found in lung, brain and spinal cord. The positive rate in brain was higher. Results showed that duplication of VSV occured mainly in lung and brain,and cause corresponding pathogenicity.展开更多
动物水泡性口炎病毒(VSV)引起动物水泡性疾病。VSV有两个主要抗原群是核酸蛋白和G蛋白抗原。G蛋白因为能产生中和性抗体被认为是在发动抑制病毒感染方面起主要作用。已经证实VSV 的New Jersey 株中产生独立的中和性单克隆抗体的抗原决...动物水泡性口炎病毒(VSV)引起动物水泡性疾病。VSV有两个主要抗原群是核酸蛋白和G蛋白抗原。G蛋白因为能产生中和性抗体被认为是在发动抑制病毒感染方面起主要作用。已经证实VSV 的New Jersey 株中产生独立的中和性单克隆抗体的抗原决定蔟分布在G 蛋白的193～289氨基酸之间。展开更多
文摘Brain, spinal cord, lung, heart and liver of mouse infected by VSV was studied using immunohistochemistry method and HE staining. The results showed that VSV can infect mouse, in earlier period of infection, lesions located mainly in lung, in anaphase of infection, lesions located mainly in brain and spinal cord. Positive cells were found in lung, brain and spinal cord. The positive rate in brain was higher. Results showed that duplication of VSV occured mainly in lung and brain,and cause corresponding pathogenicity.
