S trobilurin类杀菌剂是在具有杀菌活性的天然β-甲氧基丙烯酸酯衍生物的基础上研发出来的,具有广谱、高效、安全的特点。主要以粘噻唑为例综述了该类杀菌剂作用靶标及作用位点的研究过程及最新进展。生化作用机理的研究明确了粘噻唑作...S trobilurin类杀菌剂是在具有杀菌活性的天然β-甲氧基丙烯酸酯衍生物的基础上研发出来的,具有广谱、高效、安全的特点。主要以粘噻唑为例综述了该类杀菌剂作用靶标及作用位点的研究过程及最新进展。生化作用机理的研究明确了粘噻唑作用于线粒体呼吸链bc1复合物中的细胞色素b及铁硫蛋白,阻止了从细胞色素b到细胞色素c1的电子传递,从而抑制线粒体的呼吸作用;蛋白质晶体学研究明确了粘噻唑的作用位点(Qo位点)是通过氢键与铁硫蛋白及细胞色素b的残基结合的。其他strobilurin类杀菌剂和粘噻唑具有相同的靶标,但由于各化合物之间存在一定的结构差异,其具体作用位点亦有一定的差别。展开更多
The intensity distribution of depolarized field in the focal region of a high numerical-aperture optical system was investigated and found that the depolarization effect is tunable by the plate. The depolarization eff...The intensity distribution of depolarized field in the focal region of a high numerical-aperture optical system was investigated and found that the depolarization effect is tunable by the plate. The depolarization effect gains with the increase of the inner convergence angle of the phase plate, goes through a dramatic descent when the angle is larger than 30°, and begins to come back when the angle reaches a threshold of respectively 60°and 65° for the orthogonal diffractive field and the longitudinal diffractive fields. This reveals two convergence points where the depolarization effect is the strongest and weakest, respectively, suggesting that the pure phase plate can be a promising method for altering depolarization diffractive fields and constructing optical instruments.展开更多
基金Funded by the Natural Science Foundation of China under the Grant No. 60608009.
文摘The intensity distribution of depolarized field in the focal region of a high numerical-aperture optical system was investigated and found that the depolarization effect is tunable by the plate. The depolarization effect gains with the increase of the inner convergence angle of the phase plate, goes through a dramatic descent when the angle is larger than 30°, and begins to come back when the angle reaches a threshold of respectively 60°and 65° for the orthogonal diffractive field and the longitudinal diffractive fields. This reveals two convergence points where the depolarization effect is the strongest and weakest, respectively, suggesting that the pure phase plate can be a promising method for altering depolarization diffractive fields and constructing optical instruments.
