使用核磁技术分析复杂化合物结构,需采集多个二维核磁共振(2D NMR)图谱,通常实验耗时较长,不稳定且易分解的化合物可能因此发生结构变化,影响结构解析的准确性。为解决上述问题,该文探讨了基于NOAH(NMR by ordered acquisition using 1H...使用核磁技术分析复杂化合物结构,需采集多个二维核磁共振(2D NMR)图谱,通常实验耗时较长,不稳定且易分解的化合物可能因此发生结构变化,影响结构解析的准确性。为解决上述问题,该文探讨了基于NOAH(NMR by ordered acquisition using 1H-detection)快速采集2D NMR的实验技术。实验结果表明,该技术通过共享恢复时间,不仅节省了约60%的数据采集时间,同时提升了实验谱图的信噪比和分辨率,为化合物结构的快速鉴定和谱仪共享提供了有效方案。展开更多
In this paper,we studied the structure of fosthiazate by kinds of spectral techniques.The absorption in the UV spectrum coincides with the structure of fosthiazate.The main characteristic adsorption bands in the IR sp...In this paper,we studied the structure of fosthiazate by kinds of spectral techniques.The absorption in the UV spectrum coincides with the structure of fosthiazate.The main characteristic adsorption bands in the IR spectrum and fragment ions in the mass spectrum could be assigned rationally according to the structure of fosthiazate.In addition,several kinds of two-dimensional NMR techniques（1H-1H COSY,HMBC and HMQC）which could provide valuable information were used for the assignment of 1H NMR and （）13C NMR signals.Combining all above techniques with the element analysis,we verified the structure of fosthiazate.展开更多
文摘使用核磁技术分析复杂化合物结构,需采集多个二维核磁共振(2D NMR)图谱,通常实验耗时较长,不稳定且易分解的化合物可能因此发生结构变化,影响结构解析的准确性。为解决上述问题,该文探讨了基于NOAH(NMR by ordered acquisition using 1H-detection)快速采集2D NMR的实验技术。实验结果表明,该技术通过共享恢复时间,不仅节省了约60%的数据采集时间,同时提升了实验谱图的信噪比和分辨率,为化合物结构的快速鉴定和谱仪共享提供了有效方案。
文摘In this paper,we studied the structure of fosthiazate by kinds of spectral techniques.The absorption in the UV spectrum coincides with the structure of fosthiazate.The main characteristic adsorption bands in the IR spectrum and fragment ions in the mass spectrum could be assigned rationally according to the structure of fosthiazate.In addition,several kinds of two-dimensional NMR techniques（1H-1H COSY,HMBC and HMQC）which could provide valuable information were used for the assignment of 1H NMR and （）13C NMR signals.Combining all above techniques with the element analysis,we verified the structure of fosthiazate.
