Projective synchronization problems of a drive system and a particular response network were investigated,where the drive system is an arbitrary system with n+1 dimensions;it may be a linear or nonlinear system,and ev...Projective synchronization problems of a drive system and a particular response network were investigated,where the drive system is an arbitrary system with n+1 dimensions;it may be a linear or nonlinear system,and even a chaotic or hyperchaotic system,the response network is complex system coupled by N nodes,and every node is showed by the approximately linear part of the drive system.Only controlling any one node of the response network by designed controller can achieve the projective synchronization.Some numerical examples were employed to verify the effectiveness and correctness of the designed controller.展开更多
The work takes a new liquid-cooling plate in a power battery with pin fins inside the channel as the object.A mathematical model is established via the central composite design of the response surface to study the rel...The work takes a new liquid-cooling plate in a power battery with pin fins inside the channel as the object.A mathematical model is established via the central composite design of the response surface to study the relationships among the length,width,height,and spacing of pin fins;the maximum temperature and temperature difference of the battery module;and the pressure drop of the liquid-cooling plate.Model accuracy is verified via variance analysis.The new liquid-cooling plate enables the power battery to work within an optimal temperature range.Appropriately increasing the length,width,and height and reducing the spacing of pin fins could reduce the temperature of the power battery module and improve the temperature uniformity.However,the pressure drop of the liquid-cooling plate increases.The structural parameters of the pin fins are optimized to minimize the maximum temperature and the temperature difference of the battery module as well as the pressure drop of the liquid-cooling plate.The errors between the values predicted and actual by the simulation test are 0.58%,4%,and 0.48%,respectively,which further verifies the model accuracy.The results reveal the influence of the structural parameters of the pin fins inside the liquid-cooling plate on its heat dissipation performance and pressure drop characteristics.A theoretical basis is provided for the design of liquid-cooling plates in power batteries and the optimization of structural parameters.展开更多
Public emergencies are generally sudden with huge real or potential danger to the whole society.The COVID-19 pandemic is a typical public emergency with a long duration involving a wide range of people,and has extreme...Public emergencies are generally sudden with huge real or potential danger to the whole society.The COVID-19 pandemic is a typical public emergency with a long duration involving a wide range of people,and has extremely bad social impact.The pandemic can be classified into four stages:initial stage,outbreak stage,durative stage and post-pandemic stage.The focus of mass media varied according to the characteristics of different stages.Based on different stages,mass media should change their roles timely and always be aware of the mainstream ideological construction in public opinions to firmly control the direction of public opinion by using the theory and method of communication.展开更多
Objective To investigate whether 2,3,5,4'-tetrahydroxystilbene-2-O-β-glucoside(TSG)ameliorated polycystic ovary syndrome(PCOS)-like characteristics by inhibiting inflammation.Methods PCOS models were established ...Objective To investigate whether 2,3,5,4'-tetrahydroxystilbene-2-O-β-glucoside(TSG)ameliorated polycystic ovary syndrome(PCOS)-like characteristics by inhibiting inflammation.Methods PCOS models were established by injecting subcutaneously with dehydroepiandrosterone into female Sprague-Dawley rats,followed by receiving intraperitoneal injection of TSG.The granular cells(GCs)KGN were transfected with small interfering RNAs(si-NC and si-CYP19A1).The cells were preincubated with lipopolysaccharide(LPS)and then treated with or without TSG.The estrous cycle was monitored using vaginal exfoliated cells.The morphology of ovarian follicles was analyzed by H&E staining.ELISA was used to analyze estradiol(E2),testosterone(T),follicle stimulating hormone(FSH),luteinizing hormone(LH),IL-6,TNF-α,AGEs,CRP and Omentin-1 levels in serum.Immunohistochemistry was performed to analyze PCNA and CYP19A1 expressions in the GCs of ovaries.Tunel staining was executed to detect the apoptosis of GCs.Quantitative polymerase chain reaction(qPCR)and Western blot were implemented to measure the expression of CYP19A1 in the ovaries and transfected cells.qPCR was used to analyze the expression of IL-6 and TNF-αin the transfected cells treated with LPS and TSG.Results The estrous cycles were restored in TSG group.Compared with model group,the sinus follicles were reduced and corpus luteums were increased in TSG group.TSG group showed increased E2,and decreased T and LH,compared with model group.Pro-inflammatory factors(IL-6,TNF-α,CRP and AGEs)were decreased,and anti-inflammatory factor(Omentin-1)was increased in TSG group compared with those in model group.TSG could partially inhibit decrease of PNCA-positive GCs and increase of Tunel-positive GCs caused by PCOS.The CYP19A1 expression of GCs in TSG group was upregulated compared with model group.The expressions of IL-6 and TNFαin si-CYP19A1 cells were increased compared with si-NC cells.Compared with cells(si-NC and si-CYP19A1)treated without LPS,the expressions of IL-6 and TNF-αcells were increased,and the expression of CYP19A1 was downregulated in LPS-preincubated cells.Compared with cells treated with LPS,the expression of IL-6 and TNF-αwere decreased,and the expression of CYP19A1 was increased in cells treated with LPS and TSG.Compared with si-NC cells treated with LPS and TSG,the expressions of IL-6 and TNF-αcells were increased in the si-CYP19A1 cells treated with LPS and TSG.Conclusion TSG could alleviate PCOS-like characteristics by increasing the expression of CYP19A1 in GCs to inhibit inflammatory response.展开更多
The use of ultra-high molecular weight polyethylene(UHMWPE)composite in the design of lightweight protective equipment,has gained a lot of interest.However,there is an urgent need to understand the ballistic response ...The use of ultra-high molecular weight polyethylene(UHMWPE)composite in the design of lightweight protective equipment,has gained a lot of interest.However,there is an urgent need to understand the ballistic response mechanism and theoretical prediction model of performance.This paper explores the ballistic response mechanism of UHMWPE composite through experimental and simulation analyses.Then,a resistance-driven modeling method was proposed to establish a theoretical model for predicting the bulletproof performance.The ballistic response mechanism of UHMWPE composite encompassed three fundamental modes:local response,structural response,and coupled response.The occurrence ratio of these fundamental response modes during impact was dependent on the projectile velocity and laminate thickness.The bulletproof performance of laminate under different response modes was assessed based on the penetration depth of the projectile,the bulging height on the rear face of the laminate,the thickness of remaining sub-laminate,and residual velocity of the projectile.The absolute deviations of bulletproof performance indicator between theoretical value and experimental value were well within 11.13%,demonstrating that the established evaluation model possessed high degree of prediction accuracy.展开更多
Missile-borne short-range infrared detection(SIRD)technology is commonly used in military ground target detection.In complex battlefield environments,achieving precise strike on ground target is a challenging task.How...Missile-borne short-range infrared detection(SIRD)technology is commonly used in military ground target detection.In complex battlefield environments,achieving precise strike on ground target is a challenging task.However,real battlefield data is limited,and equivalent experiments are costly.Currently,there is a lack of comprehensive physical modeling and numerical simulation methods for SIRD.To this end,this study proposes a SIRD simulation framework incorporating full-link physical response,which is integrated through the radiative transfer layer,the sensor response layer,and the model-driven layer.In the radiative transfer layer,a coupled dynamic detection model is established to describe the external optical channel response of the SIRD system by combining the infrared radiation model and the geometric measurement model.In the sensor response layer,considering photoelectric conversion and signal processing,the internal signal response model of the SIRD system is established by a hybrid mode of parametric modeling and analog circuit analysis.In the model-driven layer,a cosimulation application based on a three-dimensional virtual environment is proposed to drive the full-link physical model,and a parallel ray tracing method is employed for real-time synchronous simulation.The proposed simulation framework can provide pixel-level signal output and is verified by the measured data.The evaluation results of the root mean square error(RMSE)and the Pearson correlation coefficient(PCC)show that the simulated data and the measured data achieve good consistency,and the evaluation results of the waveform eigenvalues indicate that the simulated signals exhibit low errors compared to the measured signals.The proposed simulation framework has the potential to acquire large sample datasets of SIRD under various complex battlefield environments and can provide an effective data source for SIRD application research.展开更多
To investigate the explosion load characteristics and structural response law in a water mist environment in a cabin,explosion experiments are carried out.The weakening rates of the initial peak overpressure,quasistat...To investigate the explosion load characteristics and structural response law in a water mist environment in a cabin,explosion experiments are carried out.The weakening rates of the initial peak overpressure,quasistatic pressure and structural residual deflection increase with increasing working pressure of the water mist nozzle.Specifically,the weakening rate of the initial peak overpressure ranges from 7.8%to 31.0%,the quasistatic pressure weakening rate ranges from 29.2%to 41.0%,and the weakening rate of the center of the plate residual deflection ranges from 10.8%to 34.4%under the various working pressures of the nozzles.To further explore the effect of water mist explosion suppression,a method for three-dimensional numerical simulations of water mist weakening the explosion shock wave is established to explore the explosion load characteristics of the compartment and the bulkhead response law.On the basis of the dimension analysis method,empirical formulas are derived to predict the residual deflection thickness in the center of the bulkheads.These findings provide the fundamental basis for the appli-cation of water mist in anti-explosive protection.展开更多
In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heati...In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heating time,microwave power,microwave heating time on the center temperature,moisture content,the chroma(C*),the total color difference(ΔE*),shape fidelity,hardness,and the total anthocyanin content of 3D printed raspberry preserves were analyzed by response surface method(RSM).The results showed that under combining with the two methods,infrared heating improved the fidelity and quality degradation of printed products,while microwave heating enhanced the efficiency of infrared heating.Infrared-microwave combination cooking could maintain relatively stable color appearance and shape of 3D printed raspberry preserves.The AHP–CRITIC hybrid weighting method combined with the response surface test to determine the comprehensive weights of the evaluation indicators optimized the process parameters,and the optimal process parameters were obtained:infrared heating temperature of 190℃,infrared heating time of 10 min and 30 s,microwave power of 300 W,and microwave heating time of 2 min and 6 s.The 3D printed raspberry cooking methods obtained under the optimal conditions seldom had color variation,porous structure,uniform texture,and high shape fidelity,which retained the characteristics of personalized manufacturing by 3D printing.This study could provide a reference for the postprocessing and quality control of 3D cooking methods.展开更多
This study designs four types of liquid-filled cylindrical shell structures to investigate their protection characteristics against explosive shock waves and high-speed fragments.Bare charge and charge-driven prefabri...This study designs four types of liquid-filled cylindrical shell structures to investigate their protection characteristics against explosive shock waves and high-speed fragments.Bare charge and charge-driven prefabricated fragments are employed to examine the damage under blast shock waves and combined blast and fragments loading on various liquid-filled cylindrical shell structures.The test results are compared to numerical calculations and theoretical analysis for the structure's deformation,the liquid medium's movement,and the pressure waves'propagation characteristics under different liquid-filling methods.The results showed that the filling method influences the blast protection and the struc-ture's energy absorption performance.The external filling method reduces the structural deformation,and the internal filling method increases the damage effect.The gapped internal filling method improves the structure's energy absorption efficiency.The pressure wave loading on the liquid-filled cylindrical shell structure differs depending on filling methods.Explosive shock waves and high-speed fragments show a damage enhancement effect on the liquid-filled cylindrical shell structure,depending on the thickness of the internal liquid container layer.The specific impulse on the inner surface of the cylindrical shell positively correlates to the radial deformation of the cylindrical shell structure,and the external liquid layer limits the radial structural deformation.展开更多
The afterburning of TNT and structural constraints in confined spaces significantly amplify the blast load,leading to severe structural damage. This study investigates the mechanisms underlying the enhanced dynamic re...The afterburning of TNT and structural constraints in confined spaces significantly amplify the blast load,leading to severe structural damage. This study investigates the mechanisms underlying the enhanced dynamic response of reinforced concrete blast doors with four-sided restraints in confined space. Explosion tests with TNT charges ranging from 0.15 kg to 0.4 kg were conducted in a confined space,capturing overpressure loads and the dynamic response of the blast door. An internal explosion model incorporating the afterburning effect was developed using LS-DYNA software and validated against experimental data. The results reveal that the TNT afterburning effect amplifies both the initial peak overpressure and the quasi-static overpressure, resulting in increased deformation of the blast door.Within the 0.15-0.4 kg charge range, the initial overpressure peak and quasi-static overpressure increased by an average of 1.79 times and 2.21 times, respectively. Additionally, the afterburning effect enhanced the blast door's deflection by 177%. Compared to open-space scenarios, the cumulative deflection of the blast door due to repeated shock wave impacts is significantly greater in confined spaces. Furthermore, the quasi-static pressure arising from the structural constraints sustains the blast door's deflection at a high level.展开更多
To investigate the mechanical response during failure and the impact tendency characteristics of gangue-coal combined structure,uniaxial compression tests were conducted on nine groups of combined structures,each with...To investigate the mechanical response during failure and the impact tendency characteristics of gangue-coal combined structure,uniaxial compression tests were conducted on nine groups of combined structures,each with varying gangue thicknesses and positions.The response patterns of compressive strength,elastic modulus,pre-peak accumulated energy,elastic energy index,and impact energy index were systematically analyzed.Furthermore,a new index for evaluating the impact tendency of gangue-containing coal was proposed,and its effectiveness was verified.The findings are as follows:(1)As the gangue thickness increases,both the compressive strength and the pre-peak energy of the combined structure decrease,whereas the elastic modulus increases accordingly.When the gangue is located in the lower middle position,the combined structure exhibits the lowest compressive strength and elastic modulus but the highest pre peak energy.(2)As the gangue shifts toward the middle position of the combined structure,the failure mode gradually transitions from comple te“crushing”failure to an incomplete“point-type”failure.As gangue thickness further increases,the failure region evolves from overall failure to localized failure,with the degree of failure shifting from complete to incomplete.The K_(crc)value corresponding to“crushing”complete failure is higher and has a stronger impact tendency compared to“point-type”incomplete failure.(3)The proposed comprehensive impact instability evaluation index K_(crc)for the gangue-coal combined structure has shown a significant positive correlation with compressive strength(R_(c))and impact energy index(K_(E)),further verifyi ng its rationality in comprehensively assessing the impact tendency of gangue-containing coal bodies.Applying this index to the evaluation of gangue-containing coal seams provides a more accurate reflection of their impact tendency compared with the residual energy index,which has a wide range of potential applications and practical significance.展开更多
Against the backdrop of the knowledge economy, global economy is goingthrough a major transformation. How to alleviate the pressure of resources and the environ-ment and to achieve the sustainable development of the e...Against the backdrop of the knowledge economy, global economy is goingthrough a major transformation. How to alleviate the pressure of resources and the environ-ment and to achieve the sustainable development of the economy has become a global agenda.China＇ s economy growth has been rapid for decades since the reform and opening up policy,but this has also been a great drain on China＇ s resources and the environment, which is an ur-gent problem to tackle. In recently years, the Chinese government has launched many environ-mental policies in the hope of encouraging technological innovation to guarantee the sustain-able development of the economy. However, research suggested that technological innovationis negatively correlated with environmental policies in most scenarios. In some cases, the num-ber of technological innovation decreases after policies take effect and increases after a whilelike a U - curve. In order to solve this problem, I decided to analyze the panel data from 80provinces in China between 2008 and 2014 and conclude that local governance can implementenvironmental regulations while having a positive impact on the technological innovation inenterprises. In the conclusion, suggestions are given to local governments on how to better en-force environmental policies.展开更多
The inter-agency government information sharing(IAGIS)plays an important role in improving service and efficiency of government agencies.Currently,there is still no effective and secure way for data-driven IAGIS to fu...The inter-agency government information sharing(IAGIS)plays an important role in improving service and efficiency of government agencies.Currently,there is still no effective and secure way for data-driven IAGIS to fulfill dynamic demands of information sharing between government agencies.Motivated by blockchain and data mining,a data-driven framework is proposed for IAGIS in this paper.Firstly,the blockchain is used as the core to design the whole framework for monitoring and preventing leakage and abuse of government information,in order to guarantee information security.Secondly,a four-layer architecture is designed for implementing the proposed framework.Thirdly,the classical data mining algorithms PageRank and Apriori are applied to dynamically design smart contracts for information sharing,for the purposed of flexibly adjusting the information sharing strategies according to the practical demands of government agencies for public management and public service.Finally,a case study is presented to illustrate the operation of the proposed framework.展开更多
This paper discusses methods for governing the global good. It holds that justice for both people and non-human creatures requires a change at the foundations of our view of life. What is needed is not only a few more...This paper discusses methods for governing the global good. It holds that justice for both people and non-human creatures requires a change at the foundations of our view of life. What is needed is not only a few more government regulations or a little more international cooperation based on the unquestioned presupposition of the priority of national sovereignty and economic growth,but also a different perspective on our responsibilities for the wellbeing of the commons, recognizing that increasingly the environmental commons is global in scope and requires some transnational means of governance. It also holds that a"responsibilities"approach calls for the greening of all kinds of responsibility and not only those of national governments and international organizations.展开更多
Since the 18th National Congress of the Communist Party of China,General Secretary Xi Jinping,with a long-term vision,has discussed social governance on different occasions in the face of contemporary issues,forming a...Since the 18th National Congress of the Communist Party of China,General Secretary Xi Jinping,with a long-term vision,has discussed social governance on different occasions in the face of contemporary issues,forming an ideological system with complete structure,rich content,rigorous exposition,and profound thinking.From the perspective of theoretical analysis,these expositions insist on people-centeredness in the value dimension,implement multiple subject participation in the practical dimension,consider promoting the legalization of social governance in the target dimension,draw on the essence of traditional cultural governance in the historical dimension,and focus on diversified governance measures in the method dimension.The important exposition of General Secretary Xi Jinping on social governance is the new development of Chinese Marxist social governance ideas,which will help the steady progress of socialist social governance with Chinese characteristics and the further improvement of socialist governance system with Chinese characteristics.展开更多
In recent years,problems such as cyber warfares,cyber espionages and cyber crimes have become global public nuisances and always challenge the authority of the sovereign states. Therefore,the governance of the derivat...In recent years,problems such as cyber warfares,cyber espionages and cyber crimes have become global public nuisances and always challenge the authority of the sovereign states. Therefore,the governance of the derivative problems concerning the global cyberspace has become an issue of importance in the international law. To overcome these challenges,sovereign states begin to get involved in cyberspace and seek international cooperation,so as to promote the evolution of the international rule of law in cyberspace. Currently,the cyberspace is filled with contradictions and conflicts. The cyber hegemonic states monopolize basic resources for cyberspaces,and their liberalism of double standards is the best tool to maintain their centralized and dominant situations. Moreover,the differences on governance problems between different camps leads to the significant institutional supply shortage. Accordingly,as a responsible power,China should advocate the Chinese solution and wisdom so as to create the reform of global cyberspace governance system. Possible specific measures include clarifying the governance structure of sovereign state-orientation,adhering to the model of shared governance with multilateral approach and multi-party participation.展开更多
With China’s reform and development entering a critical period,the interweaving of various interest relations and the superimposing of the old and new contradictions have intensified social risks.Based on the concept...With China’s reform and development entering a critical period,the interweaving of various interest relations and the superimposing of the old and new contradictions have intensified social risks.Based on the concept of“pluralism,sharing,participation,cooperation and tolerance”,social stability can be maintained by the balanced protection of civil rights and the full realization of the development strategy.In addition,with the guidance of comprehensive legal thinking and core socialist values,the legal regulation of administrative behavior and rights-protection behavior is strengthened.In this way,the win-win of maintaining rights and stability can be realized in the positive-sum game that will help resolve social risks and achieve high-quality social stability.展开更多
In this paper,to study the mechanical responses of a solid propellant subjected to ultrahigh acceleration overload during the gun-launch process,specifically designed projectile flight tests with an onboard measuremen...In this paper,to study the mechanical responses of a solid propellant subjected to ultrahigh acceleration overload during the gun-launch process,specifically designed projectile flight tests with an onboard measurement system were performed.Two projectiles containing dummy HTPB propellant grains were successfully recovered after the flight tests with an ultrahigh acceleration overload value of 8100 g.The onboard-measured time-resolved axial displacement,contact stress and overload values were successfully obtained and analysed.Uniaxial compression tests of the dummy HTPB propellant used in the gunlaunched tests were carried out at low and intermediate strain rates to characterize the propellant's dynamic properties.A linear viscoelastic constitutive model was employed and applied in finite-element simulations of the projectile-launching process.During the launch process,the dummy propellant grain exhibited large deformation due to the high acceleration overload,possibly leading to friction between the motor case and propellant grain.The calculated contact stress showed good agreement with the experimental results,though discrepancies in the overall displacement of the dummy propellant grain were observed.The dynamic mechanical response process of the dummy propellant grain was analysed in detail.The results can be used to estimate the structural integrity of the analysed dummy propellant grain during the gun-launch process.展开更多
基金Supported by the National Natural Science Foundation of China (11161027)。
文摘Projective synchronization problems of a drive system and a particular response network were investigated,where the drive system is an arbitrary system with n+1 dimensions;it may be a linear or nonlinear system,and even a chaotic or hyperchaotic system,the response network is complex system coupled by N nodes,and every node is showed by the approximately linear part of the drive system.Only controlling any one node of the response network by designed controller can achieve the projective synchronization.Some numerical examples were employed to verify the effectiveness and correctness of the designed controller.
基金supported by the Education and Teaching Research Project of Universities in Fujian Province(FBJY20230167).
文摘The work takes a new liquid-cooling plate in a power battery with pin fins inside the channel as the object.A mathematical model is established via the central composite design of the response surface to study the relationships among the length,width,height,and spacing of pin fins;the maximum temperature and temperature difference of the battery module;and the pressure drop of the liquid-cooling plate.Model accuracy is verified via variance analysis.The new liquid-cooling plate enables the power battery to work within an optimal temperature range.Appropriately increasing the length,width,and height and reducing the spacing of pin fins could reduce the temperature of the power battery module and improve the temperature uniformity.However,the pressure drop of the liquid-cooling plate increases.The structural parameters of the pin fins are optimized to minimize the maximum temperature and the temperature difference of the battery module as well as the pressure drop of the liquid-cooling plate.The errors between the values predicted and actual by the simulation test are 0.58%,4%,and 0.48%,respectively,which further verifies the model accuracy.The results reveal the influence of the structural parameters of the pin fins inside the liquid-cooling plate on its heat dissipation performance and pressure drop characteristics.A theoretical basis is provided for the design of liquid-cooling plates in power batteries and the optimization of structural parameters.
基金This paper is a milestone of“Research on Effectively Guiding the Mental Health Education of Special College Students In Jilin University”,a scientific research project planned by Jilin Provincial Education Department(Project No.:JJKH20200590SK).
文摘Public emergencies are generally sudden with huge real or potential danger to the whole society.The COVID-19 pandemic is a typical public emergency with a long duration involving a wide range of people,and has extremely bad social impact.The pandemic can be classified into four stages:initial stage,outbreak stage,durative stage and post-pandemic stage.The focus of mass media varied according to the characteristics of different stages.Based on different stages,mass media should change their roles timely and always be aware of the mainstream ideological construction in public opinions to firmly control the direction of public opinion by using the theory and method of communication.
文摘Objective To investigate whether 2,3,5,4'-tetrahydroxystilbene-2-O-β-glucoside(TSG)ameliorated polycystic ovary syndrome(PCOS)-like characteristics by inhibiting inflammation.Methods PCOS models were established by injecting subcutaneously with dehydroepiandrosterone into female Sprague-Dawley rats,followed by receiving intraperitoneal injection of TSG.The granular cells(GCs)KGN were transfected with small interfering RNAs(si-NC and si-CYP19A1).The cells were preincubated with lipopolysaccharide(LPS)and then treated with or without TSG.The estrous cycle was monitored using vaginal exfoliated cells.The morphology of ovarian follicles was analyzed by H&E staining.ELISA was used to analyze estradiol(E2),testosterone(T),follicle stimulating hormone(FSH),luteinizing hormone(LH),IL-6,TNF-α,AGEs,CRP and Omentin-1 levels in serum.Immunohistochemistry was performed to analyze PCNA and CYP19A1 expressions in the GCs of ovaries.Tunel staining was executed to detect the apoptosis of GCs.Quantitative polymerase chain reaction(qPCR)and Western blot were implemented to measure the expression of CYP19A1 in the ovaries and transfected cells.qPCR was used to analyze the expression of IL-6 and TNF-αin the transfected cells treated with LPS and TSG.Results The estrous cycles were restored in TSG group.Compared with model group,the sinus follicles were reduced and corpus luteums were increased in TSG group.TSG group showed increased E2,and decreased T and LH,compared with model group.Pro-inflammatory factors(IL-6,TNF-α,CRP and AGEs)were decreased,and anti-inflammatory factor(Omentin-1)was increased in TSG group compared with those in model group.TSG could partially inhibit decrease of PNCA-positive GCs and increase of Tunel-positive GCs caused by PCOS.The CYP19A1 expression of GCs in TSG group was upregulated compared with model group.The expressions of IL-6 and TNFαin si-CYP19A1 cells were increased compared with si-NC cells.Compared with cells(si-NC and si-CYP19A1)treated without LPS,the expressions of IL-6 and TNF-αcells were increased,and the expression of CYP19A1 was downregulated in LPS-preincubated cells.Compared with cells treated with LPS,the expression of IL-6 and TNF-αwere decreased,and the expression of CYP19A1 was increased in cells treated with LPS and TSG.Compared with si-NC cells treated with LPS and TSG,the expressions of IL-6 and TNF-αcells were increased in the si-CYP19A1 cells treated with LPS and TSG.Conclusion TSG could alleviate PCOS-like characteristics by increasing the expression of CYP19A1 in GCs to inhibit inflammatory response.
基金supported by the National Key Research and Development of China(Grant No.2022YFB4601901)the National Natural Science Foundation of China(Grant No.12122202)。
文摘The use of ultra-high molecular weight polyethylene(UHMWPE)composite in the design of lightweight protective equipment,has gained a lot of interest.However,there is an urgent need to understand the ballistic response mechanism and theoretical prediction model of performance.This paper explores the ballistic response mechanism of UHMWPE composite through experimental and simulation analyses.Then,a resistance-driven modeling method was proposed to establish a theoretical model for predicting the bulletproof performance.The ballistic response mechanism of UHMWPE composite encompassed three fundamental modes:local response,structural response,and coupled response.The occurrence ratio of these fundamental response modes during impact was dependent on the projectile velocity and laminate thickness.The bulletproof performance of laminate under different response modes was assessed based on the penetration depth of the projectile,the bulging height on the rear face of the laminate,the thickness of remaining sub-laminate,and residual velocity of the projectile.The absolute deviations of bulletproof performance indicator between theoretical value and experimental value were well within 11.13%,demonstrating that the established evaluation model possessed high degree of prediction accuracy.
基金supported by the Foundation of Equipment Preresearch Area(Grant No.80919010303).
文摘Missile-borne short-range infrared detection(SIRD)technology is commonly used in military ground target detection.In complex battlefield environments,achieving precise strike on ground target is a challenging task.However,real battlefield data is limited,and equivalent experiments are costly.Currently,there is a lack of comprehensive physical modeling and numerical simulation methods for SIRD.To this end,this study proposes a SIRD simulation framework incorporating full-link physical response,which is integrated through the radiative transfer layer,the sensor response layer,and the model-driven layer.In the radiative transfer layer,a coupled dynamic detection model is established to describe the external optical channel response of the SIRD system by combining the infrared radiation model and the geometric measurement model.In the sensor response layer,considering photoelectric conversion and signal processing,the internal signal response model of the SIRD system is established by a hybrid mode of parametric modeling and analog circuit analysis.In the model-driven layer,a cosimulation application based on a three-dimensional virtual environment is proposed to drive the full-link physical model,and a parallel ray tracing method is employed for real-time synchronous simulation.The proposed simulation framework can provide pixel-level signal output and is verified by the measured data.The evaluation results of the root mean square error(RMSE)and the Pearson correlation coefficient(PCC)show that the simulated data and the measured data achieve good consistency,and the evaluation results of the waveform eigenvalues indicate that the simulated signals exhibit low errors compared to the measured signals.The proposed simulation framework has the potential to acquire large sample datasets of SIRD under various complex battlefield environments and can provide an effective data source for SIRD application research.
基金supported by the National Natural Science Foundation of China(grant numbers:52201334)sup-ported by National Key Laboratory of Ship Structural Safety(grant numbers:Naklas2024-KF015-s).
文摘To investigate the explosion load characteristics and structural response law in a water mist environment in a cabin,explosion experiments are carried out.The weakening rates of the initial peak overpressure,quasistatic pressure and structural residual deflection increase with increasing working pressure of the water mist nozzle.Specifically,the weakening rate of the initial peak overpressure ranges from 7.8%to 31.0%,the quasistatic pressure weakening rate ranges from 29.2%to 41.0%,and the weakening rate of the center of the plate residual deflection ranges from 10.8%to 34.4%under the various working pressures of the nozzles.To further explore the effect of water mist explosion suppression,a method for three-dimensional numerical simulations of water mist weakening the explosion shock wave is established to explore the explosion load characteristics of the compartment and the bulkhead response law.On the basis of the dimension analysis method,empirical formulas are derived to predict the residual deflection thickness in the center of the bulkheads.These findings provide the fundamental basis for the appli-cation of water mist in anti-explosive protection.
基金Supported by the National Natural Science Foundation of China(32072352)。
文摘In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heating time,microwave power,microwave heating time on the center temperature,moisture content,the chroma(C*),the total color difference(ΔE*),shape fidelity,hardness,and the total anthocyanin content of 3D printed raspberry preserves were analyzed by response surface method(RSM).The results showed that under combining with the two methods,infrared heating improved the fidelity and quality degradation of printed products,while microwave heating enhanced the efficiency of infrared heating.Infrared-microwave combination cooking could maintain relatively stable color appearance and shape of 3D printed raspberry preserves.The AHP–CRITIC hybrid weighting method combined with the response surface test to determine the comprehensive weights of the evaluation indicators optimized the process parameters,and the optimal process parameters were obtained:infrared heating temperature of 190℃,infrared heating time of 10 min and 30 s,microwave power of 300 W,and microwave heating time of 2 min and 6 s.The 3D printed raspberry cooking methods obtained under the optimal conditions seldom had color variation,porous structure,uniform texture,and high shape fidelity,which retained the characteristics of personalized manufacturing by 3D printing.This study could provide a reference for the postprocessing and quality control of 3D cooking methods.
基金the National Natural Science Foundation of China(Grant Nos.52371342,52271338,52101378 and 51979277)。
文摘This study designs four types of liquid-filled cylindrical shell structures to investigate their protection characteristics against explosive shock waves and high-speed fragments.Bare charge and charge-driven prefabricated fragments are employed to examine the damage under blast shock waves and combined blast and fragments loading on various liquid-filled cylindrical shell structures.The test results are compared to numerical calculations and theoretical analysis for the structure's deformation,the liquid medium's movement,and the pressure waves'propagation characteristics under different liquid-filling methods.The results showed that the filling method influences the blast protection and the struc-ture's energy absorption performance.The external filling method reduces the structural deformation,and the internal filling method increases the damage effect.The gapped internal filling method improves the structure's energy absorption efficiency.The pressure wave loading on the liquid-filled cylindrical shell structure differs depending on filling methods.Explosive shock waves and high-speed fragments show a damage enhancement effect on the liquid-filled cylindrical shell structure,depending on the thickness of the internal liquid container layer.The specific impulse on the inner surface of the cylindrical shell positively correlates to the radial deformation of the cylindrical shell structure,and the external liquid layer limits the radial structural deformation.
基金financially supported by the National Natural Science Foundation of China (Grant No. 52278504)the Natural Science Foundation of Jiangsu Province (Grant No. BK20220141)。
文摘The afterburning of TNT and structural constraints in confined spaces significantly amplify the blast load,leading to severe structural damage. This study investigates the mechanisms underlying the enhanced dynamic response of reinforced concrete blast doors with four-sided restraints in confined space. Explosion tests with TNT charges ranging from 0.15 kg to 0.4 kg were conducted in a confined space,capturing overpressure loads and the dynamic response of the blast door. An internal explosion model incorporating the afterburning effect was developed using LS-DYNA software and validated against experimental data. The results reveal that the TNT afterburning effect amplifies both the initial peak overpressure and the quasi-static overpressure, resulting in increased deformation of the blast door.Within the 0.15-0.4 kg charge range, the initial overpressure peak and quasi-static overpressure increased by an average of 1.79 times and 2.21 times, respectively. Additionally, the afterburning effect enhanced the blast door's deflection by 177%. Compared to open-space scenarios, the cumulative deflection of the blast door due to repeated shock wave impacts is significantly greater in confined spaces. Furthermore, the quasi-static pressure arising from the structural constraints sustains the blast door's deflection at a high level.
基金Project(52274130)supported by the National Natural Science Foundation of ChinaProject(ZR2024ZD22)supported by the Major Basic Research Project of the Shandong Provincial Natural Science Foundation,China+1 种基金Project(2023375)supported by the Guizhou University Research and Innovation Team,ChinaProject(LH[2024]-026)supported by the Guizhou Science and Technology Plan Project,China。
文摘To investigate the mechanical response during failure and the impact tendency characteristics of gangue-coal combined structure,uniaxial compression tests were conducted on nine groups of combined structures,each with varying gangue thicknesses and positions.The response patterns of compressive strength,elastic modulus,pre-peak accumulated energy,elastic energy index,and impact energy index were systematically analyzed.Furthermore,a new index for evaluating the impact tendency of gangue-containing coal was proposed,and its effectiveness was verified.The findings are as follows:(1)As the gangue thickness increases,both the compressive strength and the pre-peak energy of the combined structure decrease,whereas the elastic modulus increases accordingly.When the gangue is located in the lower middle position,the combined structure exhibits the lowest compressive strength and elastic modulus but the highest pre peak energy.(2)As the gangue shifts toward the middle position of the combined structure,the failure mode gradually transitions from comple te“crushing”failure to an incomplete“point-type”failure.As gangue thickness further increases,the failure region evolves from overall failure to localized failure,with the degree of failure shifting from complete to incomplete.The K_(crc)value corresponding to“crushing”complete failure is higher and has a stronger impact tendency compared to“point-type”incomplete failure.(3)The proposed comprehensive impact instability evaluation index K_(crc)for the gangue-coal combined structure has shown a significant positive correlation with compressive strength(R_(c))and impact energy index(K_(E)),further verifyi ng its rationality in comprehensively assessing the impact tendency of gangue-containing coal bodies.Applying this index to the evaluation of gangue-containing coal seams provides a more accurate reflection of their impact tendency compared with the residual energy index,which has a wide range of potential applications and practical significance.
文摘Against the backdrop of the knowledge economy, global economy is goingthrough a major transformation. How to alleviate the pressure of resources and the environ-ment and to achieve the sustainable development of the economy has become a global agenda.China＇ s economy growth has been rapid for decades since the reform and opening up policy,but this has also been a great drain on China＇ s resources and the environment, which is an ur-gent problem to tackle. In recently years, the Chinese government has launched many environ-mental policies in the hope of encouraging technological innovation to guarantee the sustain-able development of the economy. However, research suggested that technological innovationis negatively correlated with environmental policies in most scenarios. In some cases, the num-ber of technological innovation decreases after policies take effect and increases after a whilelike a U - curve. In order to solve this problem, I decided to analyze the panel data from 80provinces in China between 2008 and 2014 and conclude that local governance can implementenvironmental regulations while having a positive impact on the technological innovation inenterprises. In the conclusion, suggestions are given to local governments on how to better en-force environmental policies.
基金Supported by the Project of Guangdong Science and Technology Department(2020B010166005)the Post-Doctoral Research Project(Z000158)+2 种基金the Ministry of Education Social Science Fund(22YJ630167)the Fund project of Department of Science and Technology of Guangdong Province(GDK TP2021032500)the Guangdong Philosophy and Social Science(GD22YYJ15).
文摘The inter-agency government information sharing(IAGIS)plays an important role in improving service and efficiency of government agencies.Currently,there is still no effective and secure way for data-driven IAGIS to fulfill dynamic demands of information sharing between government agencies.Motivated by blockchain and data mining,a data-driven framework is proposed for IAGIS in this paper.Firstly,the blockchain is used as the core to design the whole framework for monitoring and preventing leakage and abuse of government information,in order to guarantee information security.Secondly,a four-layer architecture is designed for implementing the proposed framework.Thirdly,the classical data mining algorithms PageRank and Apriori are applied to dynamically design smart contracts for information sharing,for the purposed of flexibly adjusting the information sharing strategies according to the practical demands of government agencies for public management and public service.Finally,a case study is presented to illustrate the operation of the proposed framework.
文摘This paper discusses methods for governing the global good. It holds that justice for both people and non-human creatures requires a change at the foundations of our view of life. What is needed is not only a few more government regulations or a little more international cooperation based on the unquestioned presupposition of the priority of national sovereignty and economic growth,but also a different perspective on our responsibilities for the wellbeing of the commons, recognizing that increasingly the environmental commons is global in scope and requires some transnational means of governance. It also holds that a"responsibilities"approach calls for the greening of all kinds of responsibility and not only those of national governments and international organizations.
基金funded by the Shandong Social Science Planning Project“A study of the Innovation and Development of Xi Jinping’s Thought on Social Governance in the New Era”(18CXSXJ08)Shandong Humanities and Social Sciences Project in 2019“A study of the Important Exposition of General Secretary Xi Jinping on Collaborative+1 种基金Participatory and Sharing Social Governance”(19-ZX-XS-10)Shandong Province’s Project of Science and Technology Support Plan for Young Innovation in Colleges and Universities“A study of the Internal Logic in Xi Jinping’s Thought on Socialism with Chinese Characteristics in the New Era”(2019RWB016)。
文摘Since the 18th National Congress of the Communist Party of China,General Secretary Xi Jinping,with a long-term vision,has discussed social governance on different occasions in the face of contemporary issues,forming an ideological system with complete structure,rich content,rigorous exposition,and profound thinking.From the perspective of theoretical analysis,these expositions insist on people-centeredness in the value dimension,implement multiple subject participation in the practical dimension,consider promoting the legalization of social governance in the target dimension,draw on the essence of traditional cultural governance in the historical dimension,and focus on diversified governance measures in the method dimension.The important exposition of General Secretary Xi Jinping on social governance is the new development of Chinese Marxist social governance ideas,which will help the steady progress of socialist social governance with Chinese characteristics and the further improvement of socialist governance system with Chinese characteristics.
基金funded by the Ministry of Education’s Humanities and Social Sciences Research Youth Fund Project“Research on Legal Issues in China Promoting the Construction of Cyberspace Global Governance System”(18YJC820060)Chongqing Municipal Education Commission’s Humanities and Social Sciences Research Project “Research on International Legal Institutionalization of Cyberspace Destiny Community”(20SKGH067)a phased achievement of interpretation and collaborative innovation team for the Research on Chongqing Municipal Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era。
文摘In recent years,problems such as cyber warfares,cyber espionages and cyber crimes have become global public nuisances and always challenge the authority of the sovereign states. Therefore,the governance of the derivative problems concerning the global cyberspace has become an issue of importance in the international law. To overcome these challenges,sovereign states begin to get involved in cyberspace and seek international cooperation,so as to promote the evolution of the international rule of law in cyberspace. Currently,the cyberspace is filled with contradictions and conflicts. The cyber hegemonic states monopolize basic resources for cyberspaces,and their liberalism of double standards is the best tool to maintain their centralized and dominant situations. Moreover,the differences on governance problems between different camps leads to the significant institutional supply shortage. Accordingly,as a responsible power,China should advocate the Chinese solution and wisdom so as to create the reform of global cyberspace governance system. Possible specific measures include clarifying the governance structure of sovereign state-orientation,adhering to the model of shared governance with multilateral approach and multi-party participation.
文摘With China’s reform and development entering a critical period,the interweaving of various interest relations and the superimposing of the old and new contradictions have intensified social risks.Based on the concept of“pluralism,sharing,participation,cooperation and tolerance”,social stability can be maintained by the balanced protection of civil rights and the full realization of the development strategy.In addition,with the guidance of comprehensive legal thinking and core socialist values,the legal regulation of administrative behavior and rights-protection behavior is strengthened.In this way,the win-win of maintaining rights and stability can be realized in the positive-sum game that will help resolve social risks and achieve high-quality social stability.
文摘In this paper,to study the mechanical responses of a solid propellant subjected to ultrahigh acceleration overload during the gun-launch process,specifically designed projectile flight tests with an onboard measurement system were performed.Two projectiles containing dummy HTPB propellant grains were successfully recovered after the flight tests with an ultrahigh acceleration overload value of 8100 g.The onboard-measured time-resolved axial displacement,contact stress and overload values were successfully obtained and analysed.Uniaxial compression tests of the dummy HTPB propellant used in the gunlaunched tests were carried out at low and intermediate strain rates to characterize the propellant's dynamic properties.A linear viscoelastic constitutive model was employed and applied in finite-element simulations of the projectile-launching process.During the launch process,the dummy propellant grain exhibited large deformation due to the high acceleration overload,possibly leading to friction between the motor case and propellant grain.The calculated contact stress showed good agreement with the experimental results,though discrepancies in the overall displacement of the dummy propellant grain were observed.The dynamic mechanical response process of the dummy propellant grain was analysed in detail.The results can be used to estimate the structural integrity of the analysed dummy propellant grain during the gun-launch process.
