A strategy for the green synthesis of heterocyclicβ-ketosulfides via nucleophilic substitution ofα-halogenated ketone with het-eroaryl thiols in water media is presented.Compared with the available literature report...A strategy for the green synthesis of heterocyclicβ-ketosulfides via nucleophilic substitution ofα-halogenated ketone with het-eroaryl thiols in water media is presented.Compared with the available literature reports,this new method had the advantages of base-free,additives-free,simple operation,mild condition,greenness,high efficiency,tolerance of a broad scope of substrates.Furth-more,the reaction could easily be scaled up in gram scale and the products also could easily transformed to other useful organic compounds.Mechanism investigation indicated that the tautomerism of pyrimidine-2-thiol to pyrimidine-2(1H)-thione and the hy-drogen bonds played important roles in the reaction.展开更多
颗粒调剖堵水是提高原油采收率的重要途径。了解颗粒在多孔介质中的运移沉积特性,便于颗粒制备的优化,提高颗粒与地层孔喉配伍性和封堵效率。综述了颗粒浓度值、粒径、多孔介质结构、粒径比、介质内流体参数等因素对运移沉积的影响,总...颗粒调剖堵水是提高原油采收率的重要途径。了解颗粒在多孔介质中的运移沉积特性,便于颗粒制备的优化,提高颗粒与地层孔喉配伍性和封堵效率。综述了颗粒浓度值、粒径、多孔介质结构、粒径比、介质内流体参数等因素对运移沉积的影响,总结了简化几何、介观模拟、LB-DEM(lattice Boltzmann method-discrete element method)、CFD-DEM(computational fluid dynamics-discrete element method)等模拟方法研究结果。分析表明,粒径比的临界值影响多孔介质的沉积位置和堵塞程度,粒径不同、所受力差异较大,大颗粒受水动力、重力、流体流速影响显著。多孔介质内流体流动模型尚未完全统一,Brinkman-Forchheimer-Darcy模型适用性较强,CFD-DEM方法从微观角度对介质内运移沉积流固耦合进行了验证,为非均质储层的调剖方案提供了依据。展开更多
文摘A strategy for the green synthesis of heterocyclicβ-ketosulfides via nucleophilic substitution ofα-halogenated ketone with het-eroaryl thiols in water media is presented.Compared with the available literature reports,this new method had the advantages of base-free,additives-free,simple operation,mild condition,greenness,high efficiency,tolerance of a broad scope of substrates.Furth-more,the reaction could easily be scaled up in gram scale and the products also could easily transformed to other useful organic compounds.Mechanism investigation indicated that the tautomerism of pyrimidine-2-thiol to pyrimidine-2(1H)-thione and the hy-drogen bonds played important roles in the reaction.
文摘颗粒调剖堵水是提高原油采收率的重要途径。了解颗粒在多孔介质中的运移沉积特性,便于颗粒制备的优化,提高颗粒与地层孔喉配伍性和封堵效率。综述了颗粒浓度值、粒径、多孔介质结构、粒径比、介质内流体参数等因素对运移沉积的影响,总结了简化几何、介观模拟、LB-DEM(lattice Boltzmann method-discrete element method)、CFD-DEM(computational fluid dynamics-discrete element method)等模拟方法研究结果。分析表明,粒径比的临界值影响多孔介质的沉积位置和堵塞程度,粒径不同、所受力差异较大,大颗粒受水动力、重力、流体流速影响显著。多孔介质内流体流动模型尚未完全统一,Brinkman-Forchheimer-Darcy模型适用性较强,CFD-DEM方法从微观角度对介质内运移沉积流固耦合进行了验证,为非均质储层的调剖方案提供了依据。
