High-Entropy Alloys(HEAs)exhibit significant potential across multiple domains due to their unique properties.However,conventional research methodologies face limitations in composition design,property prediction,and ...High-Entropy Alloys(HEAs)exhibit significant potential across multiple domains due to their unique properties.However,conventional research methodologies face limitations in composition design,property prediction,and process optimization,characterized by low efficiency and high costs.The integration of Artificial Intelligence(AI)technologies has provided innovative solutions for HEAs research.This review presented a detailed overview of recent advancements in AI applications for structural modeling and mechanical property prediction of HEAs.Furthermore,it discussed the advantages of big data analytics in facilitating alloy composition design and screening,quality control,and defect prediction,as well as the construction and sharing of specialized material databases.The paper also addressed the existing challenges in current AI-driven HEAs research,including issues related to data quality,model interpretability,and cross-domain knowledge integration.Additionally,it proposed prospects for the synergistic development of AI-enhanced computational materials science and experimental validation systems.展开更多
In this paper,we propose a neural network approach to learn the parameters of a class of stochastic Lotka-Volterra systems.Approximations of the mean and covariance matrix of the observational variables are obtained f...In this paper,we propose a neural network approach to learn the parameters of a class of stochastic Lotka-Volterra systems.Approximations of the mean and covariance matrix of the observational variables are obtained from the Euler-Maruyama discretization of the underlying stochastic differential equations(SDEs),based on which the loss function is built.The stochastic gradient descent method is applied in the neural network training.Numerical experiments demonstrate the effectiveness of our method.展开更多
Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To sa...Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To satisfy quality of service(QoS)requirements of various users,it is critical to research efficient routing strategies to fully utilize satellite resources.This paper proposes a multi-QoS information optimized routing algorithm based on reinforcement learning for LEO satellite networks,which guarantees high level assurance demand services to be prioritized under limited satellite resources while considering the load balancing performance of the satellite networks for low level assurance demand services to ensure the full and effective utilization of satellite resources.An auxiliary path search algorithm is proposed to accelerate the convergence of satellite routing algorithm.Simulation results show that the generated routing strategy can timely process and fully meet the QoS demands of high assurance services while effectively improving the load balancing performance of the link.展开更多
The anti-hair loss mechanism of Aquilaria sinensis leaf extract(ASE)has been studied by using metabolomics and network pharmacology.Metabolomics was utilized to comprehensively identify the active constituents of ASE,...The anti-hair loss mechanism of Aquilaria sinensis leaf extract(ASE)has been studied by using metabolomics and network pharmacology.Metabolomics was utilized to comprehensively identify the active constituents of ASE,and the network pharmacology was used to elucidate their anti-hair loss mechanism,which was verified by molecular docking technology.572 active compounds were identified from the ASE by metabolomics methods,where there are 1447 corresponding targets and 492 targets related to hair loss,totaling 88 targets.20 core active substances were identified by constructing a network between common targets and active substances,which include vanillic acid,chorionic acid,caffeic acid and apigenin.The five key targets of TNF,TP53,IL6,PPARG,and EGFR were screened out by the PPI network analysis on 88 common targets.The GO and KEGG pathway enrichment analysis showed that the inflammation,hormone balance,cell growth,proliferation,apoptosis,and oxidative stress are involved.Molecular docking studies have confirmed the high binding affinity between core active compounds and key targets.The drug similarity assessment on these core compounds suggested that they have the potential to be used as potential hair loss treatment drugs.This study elucidates the complex molecular mechanism of ASE in treating hair loss,and provides a reference for the future applications in hair care products.展开更多
Multi-agent systems often require good interoperability in the process of completing their assigned tasks.This paper first models the static structure and dynamic behavior of multiagent systems based on layered weight...Multi-agent systems often require good interoperability in the process of completing their assigned tasks.This paper first models the static structure and dynamic behavior of multiagent systems based on layered weighted scale-free community network and susceptible-infected-recovered(SIR)model.To solve the problem of difficulty in describing the changes in the structure and collaboration mode of the system under external factors,a two-dimensional Monte Carlo method and an improved dynamic Bayesian network are used to simulate the impact of external environmental factors on multi-agent systems.A collaborative information flow path optimization algorithm for agents under environmental factors is designed based on the Dijkstra algorithm.A method for evaluating system interoperability is designed based on simulation experiments,providing reference for the construction planning and optimization of organizational application of the system.Finally,the feasibility of the method is verified through case studies.展开更多
Realizing effective enhancement in the thermally conductive performance of polymer bonded explosives(PBXs) is vital for improving the resultant environmental adaptabilities of the PBXs composites. Herein, a kind of pr...Realizing effective enhancement in the thermally conductive performance of polymer bonded explosives(PBXs) is vital for improving the resultant environmental adaptabilities of the PBXs composites. Herein, a kind of primary-secondary thermally conductive network was designed by water-suspension granulation, surface coating, and hot-pressing procedures in the graphene-based PBXs composites to greatly increase the thermal conductive performance of the composites. The primary network with a threedimensional structure provided the heat-conducting skeleton, while the secondary network in the polymer matrix bridged the primary network to increase the network density. The enhancement efficiency in the thermally conductive performance of the composites reached the highest value of 59.70% at a primary-secondary network ratio of 3:1. Finite element analysis confirmed the synergistic enhancement effect of the primary and secondary thermally conductive networks. This study introduces an innovative approach to designing network structures for PBX composites, significantly enhancing their thermal conductivity.展开更多
Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,n...Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,neural oscillatory dynamics,and brain network reorganization remain unclear.This investigation seeks to systematically evaluate the therapeutic potential of rTMS as a non-invasive neuromodulatory intervention through a multimodal framework integrating clinical assessments,molecular profiling,and neurophysiological monitoring.Methods In this prospective double-blind trial,12 AD patients underwent a 14-day protocol of 20 Hz rTMS,with comprehensive multimodal assessments performed pre-and postintervention.Cognitive functioning was quantified using the mini-mental state examination(MMSE)and Montreal cognitive assessment(MOCA),while daily living capacities and neuropsychiatric profiles were respectively evaluated through the activities of daily living(ADL)scale and combined neuropsychiatric inventory(NPI)-Hamilton depression rating scale(HAMD).Peripheral blood biomarkers,specifically Aβ1-40 and phosphorylated tau(p-tau181),were analyzed to investigate the effects of rTMS on molecular metabolism.Spectral power analysis was employed to investigate rTMS-induced modulations of neural rhythms in AD patients,while brain network analyses incorporating topological properties were conducted to examine stimulus-driven network reorganization.Furthermore,systematic assessment of correlations between cognitive scale scores,blood biomarkers,and network characteristics was performed to elucidate cross-modal therapeutic associations.Results Clinically,MMSE and MOCA scores improved significantly(P<0.05).Biomarker showed that Aβ1-40 level increased(P<0.05),contrasting with p-tau181 reduction.Moreover,the levels of Aβ1-40 were positively correlated with MMSE and MOCA scores.Post-intervention analyses revealed significant modulations in oscillatory power,characterized by pronounced reductions in delta(P<0.05)and theta bands(P<0.05),while concurrent enhancements were observed in alpha,beta,and gamma band activities(all P<0.05).Network analysis revealed frequency-specific reorganization:clustering coefficients were significantly decreased in delta,theta,and alpha bands(P<0.05),while global efficiency improvement was exclusively detected in the delta band(P<0.05).The alpha band demonstrated concurrent increases in average nodal degree(P<0.05)and characteristic path length reduction(P<0.05).Further research findings indicate that the changes in the clinical scale HAMD scores before and after rTMS stimulation are negatively correlated with the changes in the blood biomarkers Aβ1-40 and p-tau181.Additionally,the changes in the clinical scales MMSE and MoCA scores were negatively correlated with the changes in the node degree of the alpha frequency band and negatively correlated with the clustering coefficient of the delta frequency band.However,the changes in MMSE scores are positively correlated with the changes in global efficiency of both the delta and alpha frequency bands.Conclusion 20 Hz rTMS targeting dorsolateral prefrontal cortex(DLPFC)significantly improves cognitive function and enhances the metabolic clearance ofβ-amyloid and tau proteins in AD patients.This neurotherapeutic effect is mechanistically associated with rTMS-mediated frequency-selective neuromodulation,which enhances the connectivity of oscillatory networks through improved neuronal synchronization and optimized topological organization of functional brain networks.These findings not only support the efficacy of rTMS as an adjunctive therapy for AD but also underscore the importance of employing multiple assessment methods—including clinical scales,blood biomarkers,and EEG——in understanding and monitoring the progression of AD.This research provides a significant theoretical foundation and empirical evidence for further exploration of rTMS applications in AD treatment.展开更多
For target tracking and localization in bearing-only sensor network,it is an essential and significant challenge to solve the problem of plug-and-play expansion while stably enhancing the accuracy of state estimation....For target tracking and localization in bearing-only sensor network,it is an essential and significant challenge to solve the problem of plug-and-play expansion while stably enhancing the accuracy of state estimation.This paper pro-poses a distributed state estimation method based on two-layer factor graph.Firstly,the measurement model of the bearing-only sensor network is constructed,and by investigating the observ-ability and the Cramer-Rao lower bound of the system model,the preconditions are analyzed.Subsequently,the location fac-tor graph and cubature information filtering algorithm of sensor node pairs are proposed for localized estimation.Building upon this foundation,the mechanism for propagating confidence mes-sages within the fusion factor graph is designed,and is extended to the entire sensor network to achieve global state estimation.Finally,groups of simulation experiments are con-ducted to compare and analyze the results,which verifies the rationality,effectiveness,and superiority of the proposed method.展开更多
Cutting off or controlling the enemy’s power supply at critical moments or strategic locations may result in a cascade failure,thus gaining an advantage in a war.However,the exist-ing cascading failure modeling analy...Cutting off or controlling the enemy’s power supply at critical moments or strategic locations may result in a cascade failure,thus gaining an advantage in a war.However,the exist-ing cascading failure modeling analysis of interdependent net-works is insufficient for describing the load characteristics and dependencies of subnetworks,and it is difficult to use for model-ing and failure analysis of power-combat(P-C)coupling net-works.This paper considers the physical characteristics of the two subnetworks and studies the mechanism of fault propaga-tion between subnetworks and across systems.Then the surviv-ability of the coupled network is evaluated.Firstly,an integrated modeling approach for the combat system and power system is predicted based on interdependent network theory.A heteroge-neous one-way interdependent network model based on proba-bility dependence is constructed.Secondly,using the operation loop theory,a load-capacity model based on combat-loop betweenness is proposed,and the cascade failure model of the P-C coupling system is investigated from three perspectives:ini-tial capacity,allocation strategy,and failure mechanism.Thirdly,survivability indexes based on load loss rate and network sur-vival rate are proposed.Finally,the P-C coupling system is con-structed based on the IEEE 118-bus system to demonstrate the proposed method.展开更多
Delay aware routing is now widely used to provide efficient network transmission. However, for newly developing or developed mobile communication networks(MCN), only limited delay data can be obtained. In such a netwo...Delay aware routing is now widely used to provide efficient network transmission. However, for newly developing or developed mobile communication networks(MCN), only limited delay data can be obtained. In such a network, the delay is with epistemic uncertainty, which makes the traditional routing scheme based on deterministic theory or probability theory not applicable. Motivated by this problem, the MCN with epistemic uncertainty is first summarized as a dynamic uncertain network based on uncertainty theory, which is widely applied to model epistemic uncertainties. Then by modeling the uncertain end-toend delay, a new delay bounded routing scheme is proposed to find the path with the maximum belief degree that satisfies the delay threshold for the dynamic uncertain network. Finally, a lowEarth-orbit satellite communication network(LEO-SCN) is used as a case to verify the effectiveness of our routing scheme. It is first modeled as a dynamic uncertain network, and then the delay bounded paths with the maximum belief degree are computed and compared under different delay thresholds.展开更多
Hypersonic Glide Vehicles(HGVs)are advanced aircraft that can achieve extremely high speeds(generally over 5 Mach)and maneuverability within the Earth's atmosphere.HGV trajectory prediction is crucial for effectiv...Hypersonic Glide Vehicles(HGVs)are advanced aircraft that can achieve extremely high speeds(generally over 5 Mach)and maneuverability within the Earth's atmosphere.HGV trajectory prediction is crucial for effective defense planning and interception strategies.In recent years,HGV trajectory prediction methods based on deep learning have the great potential to significantly enhance prediction accuracy and efficiency.However,it's still challenging to strike a balance between improving prediction performance and reducing computation costs of the deep learning trajectory prediction models.To solve this problem,we propose a new deep learning framework(FECA-LSMN)for efficient HGV trajectory prediction.The model first uses a Frequency Enhanced Channel Attention(FECA)module to facilitate the fusion of different HGV trajectory features,and then subsequently employs a Light Sampling-oriented Multi-Layer Perceptron Network(LSMN)based on simple MLP-based structures to extract long/shortterm HGV trajectory features for accurate trajectory prediction.Also,we employ a new data normalization method called reversible instance normalization(RevIN)to enhance the prediction accuracy and training stability of the network.Compared to other popular trajectory prediction models based on LSTM,GRU and Transformer,our FECA-LSMN model achieves leading or comparable performance in terms of RMSE,MAE and MAPE metrics while demonstrating notably faster computation time.The ablation experiments show that the incorporation of the FECA module significantly improves the prediction performance of the network.The RevIN data normalization technique outperforms traditional min-max normalization as well.展开更多
To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based sim...To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based simulation(NNS)method with higher accuracy and better efficiency was proposed.The NNS method consisted of three main steps.First,the parameters of blast loads,including the peak pressures and impulses of cylindrical charges with different aspect ratios(L/D)at different stand-off distances and incident angles were obtained by two-dimensional numerical simulations.Subsequently,incident shape factors of cylindrical charges with arbitrary aspect ratios were predicted by a neural network.Finally,reflected shape factors were derived and implemented into the subroutine of the ABAQUS code to modify the CONWEP model,including modifications of impulse and overpressure.The reliability of the proposed NNS method was verified by related experimental results.Remarkable accuracy improvement was acquired by the proposed NNS method compared with the unmodified CONWEP model.Moreover,huge efficiency superiority was obtained by the proposed NNS method compared with the CEL method.The proposed NNS method showed good accuracy when the scaled distance was greater than 0.2 m/kg^(1/3).It should be noted that there is no need to generate a new dataset again since the blast loads satisfy the similarity law,and the proposed NNS method can be directly used to simulate the blast loads generated by different cylindrical charges.The proposed NNS method with high efficiency and accuracy can be used as an effective method to analyze the dynamic response of structures under blast loads,and it has significant application prospects in designing protective structures.展开更多
The ammunition loading system manipulator is susceptible to gear failure due to high-frequency,heavyload reciprocating motions and the absence of protective gear components.After a fault occurs,the distribution of fau...The ammunition loading system manipulator is susceptible to gear failure due to high-frequency,heavyload reciprocating motions and the absence of protective gear components.After a fault occurs,the distribution of fault characteristics under different loads is markedly inconsistent,and data is hard to label,which makes it difficult for the traditional diagnosis method based on single-condition training to generalize to different conditions.To address these issues,the paper proposes a novel transfer discriminant neural network(TDNN)for gear fault diagnosis.Specifically,an optimized joint distribution adaptive mechanism(OJDA)is designed to solve the distribution alignment problem between two domains.To improve the classification effect within the domain and the feature recognition capability for a few labeled data,metric learning is introduced to distinguish features from different fault categories.In addition,TDNN adopts a new pseudo-label training strategy to achieve label replacement by comparing the maximum probability of the pseudo-label with the test result.The proposed TDNN is verified in the experimental data set of the artillery manipulator device,and the diagnosis can achieve 99.5%,significantly outperforming other traditional adaptation methods.展开更多
Urban air pollution has brought great troubles to physical and mental health,economic development,environmental protection,and other aspects.Predicting the changes and trends of air pollution can provide a scientific ...Urban air pollution has brought great troubles to physical and mental health,economic development,environmental protection,and other aspects.Predicting the changes and trends of air pollution can provide a scientific basis for governance and prevention efforts.In this paper,we propose an interval prediction method that considers the spatio-temporal characteristic information of PM_(2.5)signals from multiple stations.K-nearest neighbor(KNN)algorithm interpolates the lost signals in the process of collection,transmission,and storage to ensure the continuity of data.Graph generative network(GGN)is used to process time-series meteorological data with complex structures.The graph U-Nets framework is introduced into the GGN model to enhance its controllability to the graph generation process,which is beneficial to improve the efficiency and robustness of the model.In addition,sparse Bayesian regression is incorporated to improve the dimensional disaster defect of traditional kernel density estimation(KDE)interval prediction.With the support of sparse strategy,sparse Bayesian regression kernel density estimation(SBR-KDE)is very efficient in processing high-dimensional large-scale data.The PM_(2.5)data of spring,summer,autumn,and winter from 34 air quality monitoring sites in Beijing verified the accuracy,generalization,and superiority of the proposed model in interval prediction.展开更多
Objective To observe the value of self-supervised deep learning artificial intelligence(AI)noise reduction technology based on the nearest adjacent layer applicated in ultra-low dose CT(ULDCT)for urinary calculi.Metho...Objective To observe the value of self-supervised deep learning artificial intelligence(AI)noise reduction technology based on the nearest adjacent layer applicated in ultra-low dose CT(ULDCT)for urinary calculi.Methods Eighty-eight urinary calculi patients were prospectively enrolled.Low dose CT(LDCT)and ULDCT scanning were performed,and the effective dose(ED)of each scanning protocol were calculated.The patients were then randomly divided into training set(n=75)and test set(n=13),and a self-supervised deep learning AI noise reduction system based on the nearest adjacent layer constructed with ULDCT images in training set was used for reducing noise of ULDCT images in test set.In test set,the quality of ULDCT images before and after AI noise reduction were compared with LDCT images,i.e.Blind/Referenceless Image Spatial Quality Evaluator(BRISQUE)scores,image noise(SD ROI)and signal-to-noise ratio(SNR).Results The tube current,the volume CT dose index and the dose length product of abdominal ULDCT scanning protocol were all lower compared with those of LDCT scanning protocol(all P<0.05),with a decrease of ED for approximately 82.66%.For 13 patients with urinary calculi in test set,BRISQUE score showed that the quality level of ULDCT images before AI noise reduction reached 54.42%level but raised to 95.76%level of LDCT images after AI noise reduction.Both ULDCT images after AI noise reduction and LDCT images had lower SD ROI and higher SNR than ULDCT images before AI noise reduction(all adjusted P<0.05),whereas no significant difference was found between the former two(both adjusted P>0.05).Conclusion Self-supervised learning AI noise reduction technology based on the nearest adjacent layer could effectively reduce noise and improve image quality of urinary calculi ULDCT images,being conducive for clinical application of ULDCT.展开更多
To address the shortcomings of single-step decision making in the existing deep reinforcement learning based unmanned aerial vehicle(UAV)real-time path planning problem,a real-time UAV path planning algorithm based on...To address the shortcomings of single-step decision making in the existing deep reinforcement learning based unmanned aerial vehicle(UAV)real-time path planning problem,a real-time UAV path planning algorithm based on long shortterm memory(RPP-LSTM)network is proposed,which combines the memory characteristics of recurrent neural network(RNN)and the deep reinforcement learning algorithm.LSTM networks are used in this algorithm as Q-value networks for the deep Q network(DQN)algorithm,which makes the decision of the Q-value network has some memory.Thanks to LSTM network,the Q-value network can use the previous environmental information and action information which effectively avoids the problem of single-step decision considering only the current environment.Besides,the algorithm proposes a hierarchical reward and punishment function for the specific problem of UAV real-time path planning,so that the UAV can more reasonably perform path planning.Simulation verification shows that compared with the traditional feed-forward neural network(FNN)based UAV autonomous path planning algorithm,the RPP-LSTM proposed in this paper can adapt to more complex environments and has significantly improved robustness and accuracy when performing UAV real-time path planning.展开更多
Artificial intelligence(AI)technology has been increasingly used in medical field with its rapid developments.Echocardiography is one of the best imaging methods for clinical diagnosis of heart diseases,and combining ...Artificial intelligence(AI)technology has been increasingly used in medical field with its rapid developments.Echocardiography is one of the best imaging methods for clinical diagnosis of heart diseases,and combining with AI could further improve its diagnostic efficiency.Though the applications of AI in echocardiography remained at a relatively early stage,a variety of automated quantitative and analytical techniques were rapidly emerging and initially entered clinical practice.The status of clinical applications of AI in echocardiography were reviewed in this article.展开更多
Objective To observe the value of artificial intelligence(AI)models based on non-contrast chest CT for measuring bone mineral density(BMD).Methods Totally 380 subjects who underwent both non-contrast chest CT and quan...Objective To observe the value of artificial intelligence(AI)models based on non-contrast chest CT for measuring bone mineral density(BMD).Methods Totally 380 subjects who underwent both non-contrast chest CT and quantitative CT(QCT)BMD examination were retrospectively enrolled and divided into training set(n=304)and test set(n=76)at a ratio of 8∶2.The mean BMD of L1—L3 vertebrae were measured based on QCT.Spongy bones of T5—T10 vertebrae were segmented as ROI,radiomics(Rad)features were extracted,and machine learning(ML),Rad and deep learning(DL)models were constructed for classification of osteoporosis(OP)and evaluating BMD,respectively.Receiver operating characteristic curves were drawn,and area under the curves(AUC)were calculated to evaluate the efficacy of each model for classification of OP.Bland-Altman analysis and Pearson correlation analysis were performed to explore the consistency and correlation of each model with QCT for measuring BMD.Results Among ML and Rad models,ML Bagging-OP and Rad Bagging-OP had the best performances for classification of OP.In test set,AUC of ML Bagging-OP,Rad Bagging-OP and DL OP for classification of OP was 0.943,0.944 and 0.947,respectively,with no significant difference(all P>0.05).BMD obtained with all the above models had good consistency with those measured with QCT(most of the differences were within the range of Ax-G±1.96 s),which were highly positively correlated(r=0.910—0.974,all P<0.001).Conclusion AI models based on non-contrast chest CT had high efficacy for classification of OP,and good consistency of BMD measurements were found between AI models and QCT.展开更多
文摘High-Entropy Alloys(HEAs)exhibit significant potential across multiple domains due to their unique properties.However,conventional research methodologies face limitations in composition design,property prediction,and process optimization,characterized by low efficiency and high costs.The integration of Artificial Intelligence(AI)technologies has provided innovative solutions for HEAs research.This review presented a detailed overview of recent advancements in AI applications for structural modeling and mechanical property prediction of HEAs.Furthermore,it discussed the advantages of big data analytics in facilitating alloy composition design and screening,quality control,and defect prediction,as well as the construction and sharing of specialized material databases.The paper also addressed the existing challenges in current AI-driven HEAs research,including issues related to data quality,model interpretability,and cross-domain knowledge integration.Additionally,it proposed prospects for the synergistic development of AI-enhanced computational materials science and experimental validation systems.
基金Supported by the National Natural Science Foundation of China(11971458,11471310)。
文摘In this paper,we propose a neural network approach to learn the parameters of a class of stochastic Lotka-Volterra systems.Approximations of the mean and covariance matrix of the observational variables are obtained from the Euler-Maruyama discretization of the underlying stochastic differential equations(SDEs),based on which the loss function is built.The stochastic gradient descent method is applied in the neural network training.Numerical experiments demonstrate the effectiveness of our method.
基金National Key Research and Development Program(2021YFB2900604)。
文摘Low Earth orbit(LEO)satellite networks exhibit distinct characteristics,e.g.,limited resources of individual satellite nodes and dynamic network topology,which have brought many challenges for routing algorithms.To satisfy quality of service(QoS)requirements of various users,it is critical to research efficient routing strategies to fully utilize satellite resources.This paper proposes a multi-QoS information optimized routing algorithm based on reinforcement learning for LEO satellite networks,which guarantees high level assurance demand services to be prioritized under limited satellite resources while considering the load balancing performance of the satellite networks for low level assurance demand services to ensure the full and effective utilization of satellite resources.An auxiliary path search algorithm is proposed to accelerate the convergence of satellite routing algorithm.Simulation results show that the generated routing strategy can timely process and fully meet the QoS demands of high assurance services while effectively improving the load balancing performance of the link.
文摘The anti-hair loss mechanism of Aquilaria sinensis leaf extract(ASE)has been studied by using metabolomics and network pharmacology.Metabolomics was utilized to comprehensively identify the active constituents of ASE,and the network pharmacology was used to elucidate their anti-hair loss mechanism,which was verified by molecular docking technology.572 active compounds were identified from the ASE by metabolomics methods,where there are 1447 corresponding targets and 492 targets related to hair loss,totaling 88 targets.20 core active substances were identified by constructing a network between common targets and active substances,which include vanillic acid,chorionic acid,caffeic acid and apigenin.The five key targets of TNF,TP53,IL6,PPARG,and EGFR were screened out by the PPI network analysis on 88 common targets.The GO and KEGG pathway enrichment analysis showed that the inflammation,hormone balance,cell growth,proliferation,apoptosis,and oxidative stress are involved.Molecular docking studies have confirmed the high binding affinity between core active compounds and key targets.The drug similarity assessment on these core compounds suggested that they have the potential to be used as potential hair loss treatment drugs.This study elucidates the complex molecular mechanism of ASE in treating hair loss,and provides a reference for the future applications in hair care products.
基金supported by the Key R&D Projects in Jiangsu Province(BE2021729)the Key Primary Research Project of Primary Strengthening Program(KYZYJKKCJC23001).
文摘Multi-agent systems often require good interoperability in the process of completing their assigned tasks.This paper first models the static structure and dynamic behavior of multiagent systems based on layered weighted scale-free community network and susceptible-infected-recovered(SIR)model.To solve the problem of difficulty in describing the changes in the structure and collaboration mode of the system under external factors,a two-dimensional Monte Carlo method and an improved dynamic Bayesian network are used to simulate the impact of external environmental factors on multi-agent systems.A collaborative information flow path optimization algorithm for agents under environmental factors is designed based on the Dijkstra algorithm.A method for evaluating system interoperability is designed based on simulation experiments,providing reference for the construction planning and optimization of organizational application of the system.Finally,the feasibility of the method is verified through case studies.
基金supported by the National Natural Science Foundation of China (Grant Nos. 22475179 and 22275173)。
文摘Realizing effective enhancement in the thermally conductive performance of polymer bonded explosives(PBXs) is vital for improving the resultant environmental adaptabilities of the PBXs composites. Herein, a kind of primary-secondary thermally conductive network was designed by water-suspension granulation, surface coating, and hot-pressing procedures in the graphene-based PBXs composites to greatly increase the thermal conductive performance of the composites. The primary network with a threedimensional structure provided the heat-conducting skeleton, while the secondary network in the polymer matrix bridged the primary network to increase the network density. The enhancement efficiency in the thermally conductive performance of the composites reached the highest value of 59.70% at a primary-secondary network ratio of 3:1. Finite element analysis confirmed the synergistic enhancement effect of the primary and secondary thermally conductive networks. This study introduces an innovative approach to designing network structures for PBX composites, significantly enhancing their thermal conductivity.
文摘Objective Repetitive transcranial magnetic stimulation(rTMS)has demonstrated efficacy in enhancing neurocognitive performance in Alzheimer’s disease(AD),but the neurobiological mechanisms linking synaptic pathology,neural oscillatory dynamics,and brain network reorganization remain unclear.This investigation seeks to systematically evaluate the therapeutic potential of rTMS as a non-invasive neuromodulatory intervention through a multimodal framework integrating clinical assessments,molecular profiling,and neurophysiological monitoring.Methods In this prospective double-blind trial,12 AD patients underwent a 14-day protocol of 20 Hz rTMS,with comprehensive multimodal assessments performed pre-and postintervention.Cognitive functioning was quantified using the mini-mental state examination(MMSE)and Montreal cognitive assessment(MOCA),while daily living capacities and neuropsychiatric profiles were respectively evaluated through the activities of daily living(ADL)scale and combined neuropsychiatric inventory(NPI)-Hamilton depression rating scale(HAMD).Peripheral blood biomarkers,specifically Aβ1-40 and phosphorylated tau(p-tau181),were analyzed to investigate the effects of rTMS on molecular metabolism.Spectral power analysis was employed to investigate rTMS-induced modulations of neural rhythms in AD patients,while brain network analyses incorporating topological properties were conducted to examine stimulus-driven network reorganization.Furthermore,systematic assessment of correlations between cognitive scale scores,blood biomarkers,and network characteristics was performed to elucidate cross-modal therapeutic associations.Results Clinically,MMSE and MOCA scores improved significantly(P<0.05).Biomarker showed that Aβ1-40 level increased(P<0.05),contrasting with p-tau181 reduction.Moreover,the levels of Aβ1-40 were positively correlated with MMSE and MOCA scores.Post-intervention analyses revealed significant modulations in oscillatory power,characterized by pronounced reductions in delta(P<0.05)and theta bands(P<0.05),while concurrent enhancements were observed in alpha,beta,and gamma band activities(all P<0.05).Network analysis revealed frequency-specific reorganization:clustering coefficients were significantly decreased in delta,theta,and alpha bands(P<0.05),while global efficiency improvement was exclusively detected in the delta band(P<0.05).The alpha band demonstrated concurrent increases in average nodal degree(P<0.05)and characteristic path length reduction(P<0.05).Further research findings indicate that the changes in the clinical scale HAMD scores before and after rTMS stimulation are negatively correlated with the changes in the blood biomarkers Aβ1-40 and p-tau181.Additionally,the changes in the clinical scales MMSE and MoCA scores were negatively correlated with the changes in the node degree of the alpha frequency band and negatively correlated with the clustering coefficient of the delta frequency band.However,the changes in MMSE scores are positively correlated with the changes in global efficiency of both the delta and alpha frequency bands.Conclusion 20 Hz rTMS targeting dorsolateral prefrontal cortex(DLPFC)significantly improves cognitive function and enhances the metabolic clearance ofβ-amyloid and tau proteins in AD patients.This neurotherapeutic effect is mechanistically associated with rTMS-mediated frequency-selective neuromodulation,which enhances the connectivity of oscillatory networks through improved neuronal synchronization and optimized topological organization of functional brain networks.These findings not only support the efficacy of rTMS as an adjunctive therapy for AD but also underscore the importance of employing multiple assessment methods—including clinical scales,blood biomarkers,and EEG——in understanding and monitoring the progression of AD.This research provides a significant theoretical foundation and empirical evidence for further exploration of rTMS applications in AD treatment.
基金supported by the National Natural Science Foundation of China(62176214).
文摘For target tracking and localization in bearing-only sensor network,it is an essential and significant challenge to solve the problem of plug-and-play expansion while stably enhancing the accuracy of state estimation.This paper pro-poses a distributed state estimation method based on two-layer factor graph.Firstly,the measurement model of the bearing-only sensor network is constructed,and by investigating the observ-ability and the Cramer-Rao lower bound of the system model,the preconditions are analyzed.Subsequently,the location fac-tor graph and cubature information filtering algorithm of sensor node pairs are proposed for localized estimation.Building upon this foundation,the mechanism for propagating confidence mes-sages within the fusion factor graph is designed,and is extended to the entire sensor network to achieve global state estimation.Finally,groups of simulation experiments are con-ducted to compare and analyze the results,which verifies the rationality,effectiveness,and superiority of the proposed method.
基金supported by the National Natural Science Foundation of China(72271242)Hunan Provincial Natural Science Foundation of China for Excellent Young Scholars(2022JJ20046).
文摘Cutting off or controlling the enemy’s power supply at critical moments or strategic locations may result in a cascade failure,thus gaining an advantage in a war.However,the exist-ing cascading failure modeling analysis of interdependent net-works is insufficient for describing the load characteristics and dependencies of subnetworks,and it is difficult to use for model-ing and failure analysis of power-combat(P-C)coupling net-works.This paper considers the physical characteristics of the two subnetworks and studies the mechanism of fault propaga-tion between subnetworks and across systems.Then the surviv-ability of the coupled network is evaluated.Firstly,an integrated modeling approach for the combat system and power system is predicted based on interdependent network theory.A heteroge-neous one-way interdependent network model based on proba-bility dependence is constructed.Secondly,using the operation loop theory,a load-capacity model based on combat-loop betweenness is proposed,and the cascade failure model of the P-C coupling system is investigated from three perspectives:ini-tial capacity,allocation strategy,and failure mechanism.Thirdly,survivability indexes based on load loss rate and network sur-vival rate are proposed.Finally,the P-C coupling system is con-structed based on the IEEE 118-bus system to demonstrate the proposed method.
基金National Natural Science Foundation of China (61773044,62073009)National key Laboratory of Science and Technology on Reliability and Environmental Engineering(WDZC2019601A301)。
文摘Delay aware routing is now widely used to provide efficient network transmission. However, for newly developing or developed mobile communication networks(MCN), only limited delay data can be obtained. In such a network, the delay is with epistemic uncertainty, which makes the traditional routing scheme based on deterministic theory or probability theory not applicable. Motivated by this problem, the MCN with epistemic uncertainty is first summarized as a dynamic uncertain network based on uncertainty theory, which is widely applied to model epistemic uncertainties. Then by modeling the uncertain end-toend delay, a new delay bounded routing scheme is proposed to find the path with the maximum belief degree that satisfies the delay threshold for the dynamic uncertain network. Finally, a lowEarth-orbit satellite communication network(LEO-SCN) is used as a case to verify the effectiveness of our routing scheme. It is first modeled as a dynamic uncertain network, and then the delay bounded paths with the maximum belief degree are computed and compared under different delay thresholds.
文摘Hypersonic Glide Vehicles(HGVs)are advanced aircraft that can achieve extremely high speeds(generally over 5 Mach)and maneuverability within the Earth's atmosphere.HGV trajectory prediction is crucial for effective defense planning and interception strategies.In recent years,HGV trajectory prediction methods based on deep learning have the great potential to significantly enhance prediction accuracy and efficiency.However,it's still challenging to strike a balance between improving prediction performance and reducing computation costs of the deep learning trajectory prediction models.To solve this problem,we propose a new deep learning framework(FECA-LSMN)for efficient HGV trajectory prediction.The model first uses a Frequency Enhanced Channel Attention(FECA)module to facilitate the fusion of different HGV trajectory features,and then subsequently employs a Light Sampling-oriented Multi-Layer Perceptron Network(LSMN)based on simple MLP-based structures to extract long/shortterm HGV trajectory features for accurate trajectory prediction.Also,we employ a new data normalization method called reversible instance normalization(RevIN)to enhance the prediction accuracy and training stability of the network.Compared to other popular trajectory prediction models based on LSTM,GRU and Transformer,our FECA-LSMN model achieves leading or comparable performance in terms of RMSE,MAE and MAPE metrics while demonstrating notably faster computation time.The ablation experiments show that the incorporation of the FECA module significantly improves the prediction performance of the network.The RevIN data normalization technique outperforms traditional min-max normalization as well.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.52271317 and 52071149)the Fundamental Research Funds for the Central Universities(HUST:2019kfy XJJS007)。
文摘To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian(CEL)method in predicting close-range air blast loads of cylindrical charges,a neural network-based simulation(NNS)method with higher accuracy and better efficiency was proposed.The NNS method consisted of three main steps.First,the parameters of blast loads,including the peak pressures and impulses of cylindrical charges with different aspect ratios(L/D)at different stand-off distances and incident angles were obtained by two-dimensional numerical simulations.Subsequently,incident shape factors of cylindrical charges with arbitrary aspect ratios were predicted by a neural network.Finally,reflected shape factors were derived and implemented into the subroutine of the ABAQUS code to modify the CONWEP model,including modifications of impulse and overpressure.The reliability of the proposed NNS method was verified by related experimental results.Remarkable accuracy improvement was acquired by the proposed NNS method compared with the unmodified CONWEP model.Moreover,huge efficiency superiority was obtained by the proposed NNS method compared with the CEL method.The proposed NNS method showed good accuracy when the scaled distance was greater than 0.2 m/kg^(1/3).It should be noted that there is no need to generate a new dataset again since the blast loads satisfy the similarity law,and the proposed NNS method can be directly used to simulate the blast loads generated by different cylindrical charges.The proposed NNS method with high efficiency and accuracy can be used as an effective method to analyze the dynamic response of structures under blast loads,and it has significant application prospects in designing protective structures.
文摘The ammunition loading system manipulator is susceptible to gear failure due to high-frequency,heavyload reciprocating motions and the absence of protective gear components.After a fault occurs,the distribution of fault characteristics under different loads is markedly inconsistent,and data is hard to label,which makes it difficult for the traditional diagnosis method based on single-condition training to generalize to different conditions.To address these issues,the paper proposes a novel transfer discriminant neural network(TDNN)for gear fault diagnosis.Specifically,an optimized joint distribution adaptive mechanism(OJDA)is designed to solve the distribution alignment problem between two domains.To improve the classification effect within the domain and the feature recognition capability for a few labeled data,metric learning is introduced to distinguish features from different fault categories.In addition,TDNN adopts a new pseudo-label training strategy to achieve label replacement by comparing the maximum probability of the pseudo-label with the test result.The proposed TDNN is verified in the experimental data set of the artillery manipulator device,and the diagnosis can achieve 99.5%,significantly outperforming other traditional adaptation methods.
基金Project(2020YFC2008605)supported by the National Key Research and Development Project of ChinaProject(52072412)supported by the National Natural Science Foundation of ChinaProject(2021JJ30359)supported by the Natural Science Foundation of Hunan Province,China。
文摘Urban air pollution has brought great troubles to physical and mental health,economic development,environmental protection,and other aspects.Predicting the changes and trends of air pollution can provide a scientific basis for governance and prevention efforts.In this paper,we propose an interval prediction method that considers the spatio-temporal characteristic information of PM_(2.5)signals from multiple stations.K-nearest neighbor(KNN)algorithm interpolates the lost signals in the process of collection,transmission,and storage to ensure the continuity of data.Graph generative network(GGN)is used to process time-series meteorological data with complex structures.The graph U-Nets framework is introduced into the GGN model to enhance its controllability to the graph generation process,which is beneficial to improve the efficiency and robustness of the model.In addition,sparse Bayesian regression is incorporated to improve the dimensional disaster defect of traditional kernel density estimation(KDE)interval prediction.With the support of sparse strategy,sparse Bayesian regression kernel density estimation(SBR-KDE)is very efficient in processing high-dimensional large-scale data.The PM_(2.5)data of spring,summer,autumn,and winter from 34 air quality monitoring sites in Beijing verified the accuracy,generalization,and superiority of the proposed model in interval prediction.
文摘Objective To observe the value of self-supervised deep learning artificial intelligence(AI)noise reduction technology based on the nearest adjacent layer applicated in ultra-low dose CT(ULDCT)for urinary calculi.Methods Eighty-eight urinary calculi patients were prospectively enrolled.Low dose CT(LDCT)and ULDCT scanning were performed,and the effective dose(ED)of each scanning protocol were calculated.The patients were then randomly divided into training set(n=75)and test set(n=13),and a self-supervised deep learning AI noise reduction system based on the nearest adjacent layer constructed with ULDCT images in training set was used for reducing noise of ULDCT images in test set.In test set,the quality of ULDCT images before and after AI noise reduction were compared with LDCT images,i.e.Blind/Referenceless Image Spatial Quality Evaluator(BRISQUE)scores,image noise(SD ROI)and signal-to-noise ratio(SNR).Results The tube current,the volume CT dose index and the dose length product of abdominal ULDCT scanning protocol were all lower compared with those of LDCT scanning protocol(all P<0.05),with a decrease of ED for approximately 82.66%.For 13 patients with urinary calculi in test set,BRISQUE score showed that the quality level of ULDCT images before AI noise reduction reached 54.42%level but raised to 95.76%level of LDCT images after AI noise reduction.Both ULDCT images after AI noise reduction and LDCT images had lower SD ROI and higher SNR than ULDCT images before AI noise reduction(all adjusted P<0.05),whereas no significant difference was found between the former two(both adjusted P>0.05).Conclusion Self-supervised learning AI noise reduction technology based on the nearest adjacent layer could effectively reduce noise and improve image quality of urinary calculi ULDCT images,being conducive for clinical application of ULDCT.
基金supported by the Natural Science Basic Research Prog ram of Shaanxi(2022JQ-593)。
文摘To address the shortcomings of single-step decision making in the existing deep reinforcement learning based unmanned aerial vehicle(UAV)real-time path planning problem,a real-time UAV path planning algorithm based on long shortterm memory(RPP-LSTM)network is proposed,which combines the memory characteristics of recurrent neural network(RNN)and the deep reinforcement learning algorithm.LSTM networks are used in this algorithm as Q-value networks for the deep Q network(DQN)algorithm,which makes the decision of the Q-value network has some memory.Thanks to LSTM network,the Q-value network can use the previous environmental information and action information which effectively avoids the problem of single-step decision considering only the current environment.Besides,the algorithm proposes a hierarchical reward and punishment function for the specific problem of UAV real-time path planning,so that the UAV can more reasonably perform path planning.Simulation verification shows that compared with the traditional feed-forward neural network(FNN)based UAV autonomous path planning algorithm,the RPP-LSTM proposed in this paper can adapt to more complex environments and has significantly improved robustness and accuracy when performing UAV real-time path planning.
文摘Artificial intelligence(AI)technology has been increasingly used in medical field with its rapid developments.Echocardiography is one of the best imaging methods for clinical diagnosis of heart diseases,and combining with AI could further improve its diagnostic efficiency.Though the applications of AI in echocardiography remained at a relatively early stage,a variety of automated quantitative and analytical techniques were rapidly emerging and initially entered clinical practice.The status of clinical applications of AI in echocardiography were reviewed in this article.
文摘Objective To observe the value of artificial intelligence(AI)models based on non-contrast chest CT for measuring bone mineral density(BMD).Methods Totally 380 subjects who underwent both non-contrast chest CT and quantitative CT(QCT)BMD examination were retrospectively enrolled and divided into training set(n=304)and test set(n=76)at a ratio of 8∶2.The mean BMD of L1—L3 vertebrae were measured based on QCT.Spongy bones of T5—T10 vertebrae were segmented as ROI,radiomics(Rad)features were extracted,and machine learning(ML),Rad and deep learning(DL)models were constructed for classification of osteoporosis(OP)and evaluating BMD,respectively.Receiver operating characteristic curves were drawn,and area under the curves(AUC)were calculated to evaluate the efficacy of each model for classification of OP.Bland-Altman analysis and Pearson correlation analysis were performed to explore the consistency and correlation of each model with QCT for measuring BMD.Results Among ML and Rad models,ML Bagging-OP and Rad Bagging-OP had the best performances for classification of OP.In test set,AUC of ML Bagging-OP,Rad Bagging-OP and DL OP for classification of OP was 0.943,0.944 and 0.947,respectively,with no significant difference(all P>0.05).BMD obtained with all the above models had good consistency with those measured with QCT(most of the differences were within the range of Ax-G±1.96 s),which were highly positively correlated(r=0.910—0.974,all P<0.001).Conclusion AI models based on non-contrast chest CT had high efficacy for classification of OP,and good consistency of BMD measurements were found between AI models and QCT.
