Psoriasis is a chronic,refractory,inflammatory skin disease that occurs in young adults.The traditional animal model cannot simulate the skin characteristics of patients with psoriasis effectively,so it is difficult t...Psoriasis is a chronic,refractory,inflammatory skin disease that occurs in young adults.The traditional animal model cannot simulate the skin characteristics of patients with psoriasis effectively,so it is difficult to be used for in-depth study of psoriasis mechanism.Immortalized human epidermal cells(HaCaT) is a non-tumor,immortalized human epidermal cell which is widely used in the study of dermatosis.HaCaT cells are the best choice for the study of psoriasis mechanism because their immu.nological characteristics and reproductive ability are coincide with the pathological features of psoriasis.This article reviews the specific methods such as establishment of cell method,cytokine and chemo.kine analysisin the pathogenesis study of psoriasis based on HaCaT cells,hoping to provide some thoughts for drug′s pharmacological activity research.展开更多
Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,e Book ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.T...Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,e Book ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic guides readers through methods for the analyses of chromatin remodeling,transposable elements,展开更多
Epilepsy Towards the Next Decade(ISBN:978-3-319-12282-3,eBook ISBN:978-3-319-12283-0)was published by Springer International Publishing in 2015.The editor of this book is Pasquale Striano,Pediatric Neurology and Muscu...Epilepsy Towards the Next Decade(ISBN:978-3-319-12282-3,eBook ISBN:978-3-319-12283-0)was published by Springer International Publishing in 2015.The editor of this book is Pasquale Striano,Pediatric Neurology and Muscular Diseases Unit,University of Genoa.This volume is a comprehensive collection of the most recent knowledge on the biological bases of various kinds of展开更多
Association mapping(as opposed to population mapping) is becoming more important in establishing associations between a phenotype and a genotype.The major advantage of association mapping,
文摘Psoriasis is a chronic,refractory,inflammatory skin disease that occurs in young adults.The traditional animal model cannot simulate the skin characteristics of patients with psoriasis effectively,so it is difficult to be used for in-depth study of psoriasis mechanism.Immortalized human epidermal cells(HaCaT) is a non-tumor,immortalized human epidermal cell which is widely used in the study of dermatosis.HaCaT cells are the best choice for the study of psoriasis mechanism because their immu.nological characteristics and reproductive ability are coincide with the pathological features of psoriasis.This article reviews the specific methods such as establishment of cell method,cytokine and chemo.kine analysisin the pathogenesis study of psoriasis based on HaCaT cells,hoping to provide some thoughts for drug′s pharmacological activity research.
文摘Epigenetic Methods in Neuroscience Research(ISBN:978-1-4939-2753-1,e Book ISBN:978-1-4939-2754-8)was published by Springer in 2016.The editor of this book is Nina N.Karpova,Neuroscience Center,University of Helsinki.This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic guides readers through methods for the analyses of chromatin remodeling,transposable elements,
文摘Epilepsy Towards the Next Decade(ISBN:978-3-319-12282-3,eBook ISBN:978-3-319-12283-0)was published by Springer International Publishing in 2015.The editor of this book is Pasquale Striano,Pediatric Neurology and Muscular Diseases Unit,University of Genoa.This volume is a comprehensive collection of the most recent knowledge on the biological bases of various kinds of
文摘Association mapping(as opposed to population mapping) is becoming more important in establishing associations between a phenotype and a genotype.The major advantage of association mapping,