We combined the similar simulation with numerical simulation to analyze the movement and deforma- tion features of overlying strata caused by paste backfill mining, study the movement and deformation laws of the overl...We combined the similar simulation with numerical simulation to analyze the movement and deforma- tion features of overlying strata caused by paste backfill mining, study the movement and deformation laws of the overlying strata in paste backfill mining, structural movement of the stope strata as well as the stope stress distribution laws. Furthermore, authors also explored the key factors to the movement and deformation of the overlying strata in paste backfill mining. The results indicate that a caving zone existed in the bending zone only in the overlying strata of the paste backfill mining. Compared with the roof caving mining, the degree of stress concentration and area of influence in the paste filling stope were apparently smaller. And the degree of destruction and area of the overlying strata decreased prominently. Also, there was no apparent strata behavior in the working face. Lastly, the filling ratio was the key to control the movement and deformation of the overlying strata. Combined with a specific engineering example, the author proved the reliability of the simulation results and provided a theoretical basis for the further extension of the paste backfill mining.展开更多
以牡丹籽壳为原料,利用大孔树脂和C18反相键合硅胶柱(C18柱)联合分离短叶松素,回收率为(98.33±0.64)%。用70%(体积分数)乙醇提取牡丹籽壳粗黄酮(Mu Dan Ke Flavonoids,MDKF),得率最高为(10.54±0.13)%;比较了6种大孔树脂(AB-8...以牡丹籽壳为原料,利用大孔树脂和C18反相键合硅胶柱(C18柱)联合分离短叶松素,回收率为(98.33±0.64)%。用70%(体积分数)乙醇提取牡丹籽壳粗黄酮(Mu Dan Ke Flavonoids,MDKF),得率最高为(10.54±0.13)%;比较了6种大孔树脂(AB-8、S-8、DM301、HPD600、HPD100和D101)的吸附率和解析率,发现S-8大孔树脂的吸附率和解析率最佳,分别为83.47%和84.46%;优化S-8大孔树脂分离MDKF的最佳条件为:上样液质量浓度1.6 mg/mL,上样液流速2.0 mL/min,洗脱剂乙醇体积分数60%,洗脱液流速1.5 mL/min,洗脱液体积100 mL;对经过C18柱分离后的组分进行LC-MS分析得到短叶松素,回收率为(98.33±0.64)%;分离前后抗氧化能力比较:C18纯化物>S-8大孔树脂纯化物>MDKF粗提物;分子对接实验表明,短叶松素与超氧化物歧化酶、过氧化氢酶、过氧化物酶、谷胱甘肽过氧化物酶均有结合能力,过氧化氢酶的结合能力最强为-9.1 kcal/mol。实验表明,短叶松素具有较好的抗氧化能力,可作为食品、药品或化妆品等抗氧化剂的添加,应用前景非常广泛,对牡丹籽壳的进一步开发利用提供理论支持。展开更多
基金supported by the National Natural Science Foundation of China (No. 50774077)the Special Funds of Universities Outstanding Doctoral Dissertation (No. 200760)+1 种基金the Independent Research Funding of the State Key Laboratory of Coal Resources and Mine Safety (No. SKLCRSM10X02)the Fundamental Research Funds for the Central Universities (Nos. 2010QNA31 and2010QNA32)
文摘We combined the similar simulation with numerical simulation to analyze the movement and deforma- tion features of overlying strata caused by paste backfill mining, study the movement and deformation laws of the overlying strata in paste backfill mining, structural movement of the stope strata as well as the stope stress distribution laws. Furthermore, authors also explored the key factors to the movement and deformation of the overlying strata in paste backfill mining. The results indicate that a caving zone existed in the bending zone only in the overlying strata of the paste backfill mining. Compared with the roof caving mining, the degree of stress concentration and area of influence in the paste filling stope were apparently smaller. And the degree of destruction and area of the overlying strata decreased prominently. Also, there was no apparent strata behavior in the working face. Lastly, the filling ratio was the key to control the movement and deformation of the overlying strata. Combined with a specific engineering example, the author proved the reliability of the simulation results and provided a theoretical basis for the further extension of the paste backfill mining.
文摘以牡丹籽壳为原料,利用大孔树脂和C18反相键合硅胶柱(C18柱)联合分离短叶松素,回收率为(98.33±0.64)%。用70%(体积分数)乙醇提取牡丹籽壳粗黄酮(Mu Dan Ke Flavonoids,MDKF),得率最高为(10.54±0.13)%;比较了6种大孔树脂(AB-8、S-8、DM301、HPD600、HPD100和D101)的吸附率和解析率,发现S-8大孔树脂的吸附率和解析率最佳,分别为83.47%和84.46%;优化S-8大孔树脂分离MDKF的最佳条件为:上样液质量浓度1.6 mg/mL,上样液流速2.0 mL/min,洗脱剂乙醇体积分数60%,洗脱液流速1.5 mL/min,洗脱液体积100 mL;对经过C18柱分离后的组分进行LC-MS分析得到短叶松素,回收率为(98.33±0.64)%;分离前后抗氧化能力比较:C18纯化物>S-8大孔树脂纯化物>MDKF粗提物;分子对接实验表明,短叶松素与超氧化物歧化酶、过氧化氢酶、过氧化物酶、谷胱甘肽过氧化物酶均有结合能力,过氧化氢酶的结合能力最强为-9.1 kcal/mol。实验表明,短叶松素具有较好的抗氧化能力,可作为食品、药品或化妆品等抗氧化剂的添加,应用前景非常广泛,对牡丹籽壳的进一步开发利用提供理论支持。
